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Search Results for " lpg "

Targets Recommended: GPR

14

抑制剂 & 化合物

8

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T15388	GLPG0974 GLPG-0974	GPR	Endocrinology/Hormones; GPCR/G Protein
	GLPG0974 是 FFA2/GPR43 的拮抗剂，IC50 为 9 nM。
T7083	GLPG1837 ABBV-974	CFTR; Autophagy	Autophagy; Membrane transporter/Ion channel
	GLPG1837 (ABBV-974) 是一种有效的 CFTR 增强剂，对其 F508del 和 G551D 的 EC50 分别为 3 nM 和 339 nM。
T75113	GLPG2534 GLPG-2534	IRAK	Immunology/Inflammation; NF-κB
	GLPG2534 是一种具有口服活性、选择性和有效性的 IRAK4 抑制剂，具有抗炎活性。GLPG2534 对人和小鼠 IRAK4 具有抑制作用，可用于研究银屑病和特应性皮炎。
T11411	GLPG1205	GPR; Others	Endocrinology/Hormones; GPCR/G Protein; Others
	GLPG1205是一种有效的、具有口服活性的 GPR84（G 蛋白偶联受体）拮抗剂，具有抗炎活性。GLPG1205显示出良好的PK/PD 特征，可用于研究肺纤维化。
T11410L	GLPG0492	Androgen Receptor	Endocrinology/Hormones
	GLPG0492 是一种非甾体选择性雄激素受体 (androgen receptor) 调节剂。GLPG0492 在肌肉骨骼疾病如肌萎缩和恶病质的研究方面具有潜在的潜力。
T4259	GLPG0187	Integrin	Cytoskeletal Signaling
	GLPG0187是整联蛋白受体的广谱拮抗剂，抑制αvβ1-integrin 的IC50值为1.3 nM，具有抗肿瘤活性。
T3076	GLPG0634 analog GLPG0634 analogue	Tyrosine Kinases; JAK	Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
	GLPG0634 analog (GLPG0634 analogue) 是一种 JAK 广谱性抑制剂，对 JAK1/JAK2/JAK3 的 IC50值为 50 到 200 nM 之间。
T73384	GLPG3970
	GLPG3970 是一类首创的 SIK2/SIK3抑制剂。GLPG3970 可用于炎症和自身免疫性疾病的研究。
T9199	GLPG2938 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea	S1P Receptor; LPL Receptor	GPCR/G Protein
	GLPG2938 (1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea) 是一种选择性 S1P2拮抗剂，可用于特发性肺纤维化的研究。
T27416	GLPG0259 GLPG-0259,GLPG 0259
	GLPG-0259 is an inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5).
T11410	GLPG0492 (R enantiomer) GLPG0492 R enantiomer	Others	Others
	GLPG0492 R enantiomer is the R enantiomer of GLPG-0492, a novel selective androgen receptor modulator.
T71274	GLPG0259 A
	GLPG0259 A is a small-molecule inhibitor of mitogen-activated protein kinase-activated protein kinase 5 (MAPKAPK5), a kinase enzyme that plays a role in important inflammatory pathways.
T13705	GLPG2451	Cysteine Protease	Proteases/Proteasome
	GLPG2451 is a cystic fibrosis transmembrane conductance regulator (CFTR) potentiator. It effectively potentiates low temperature rescued F508del CFTR (EC50: 11.1 nM).
T13704	GLPG-3221	Others	Others
	GLPG-3221 can be uesd for the treatment of cystic fibrosis.GLPG-3221 is a potent, orally active corrector of CFTR (cystic fibrosis transmembrane conductance regulator), with an EC50 of 105 nM.

化合物

Cat.No: T15388

Synonym: GLPG-0974

Target: GPR

Cat.No: T7083

Synonym: ABBV-974

Target: CFTR, Autophagy

Cat.No: T75113

Synonym: GLPG-2534

Target: IRAK

Cat.No: T11411

Target: GPR, Others

Cat.No: T11410L

Target: Androgen Receptor

Cat.No: T4259

Target: Integrin

GLPG0634 analog

Cat.No: T3076

Synonym: GLPG0634 analogue

Target: Tyrosine Kinases, JAK

Cat.No: T73384

Cat.No: T9199

Synonym: 1-(2-Ethoxy-6-(trifluoromethyl)pyridin-4-yl)-3-((5-methyl-6-(1-methyl-3-(trifluoromethyl)-1H-pyrazol-4-yl)pyridazin-3-yl)methyl)urea

Target: S1P Receptor, LPL Receptor

Cat.No: T27416

Synonym: GLPG-0259,GLPG 0259

GLPG0492 (R enantiomer)

Cat.No: T11410

Synonym: GLPG0492 R enantiomer

Target: Others

Cat.No: T71274

Cat.No: T13705

Target: Cysteine Protease

Cat.No: T13704

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-05297	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) LPG,apolipoprotein E,ApoE4,APO-E,LDLCQ5,AD2	Human	E. coli
	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx) is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.
TMPY-05528	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated APO-E,LDLCQ5,LPG,ApoE4,AD2,apolipoprotein E	Human	E. coli
	Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated is expressed in E. coli expression system with His and Trx tag. The predicted molecular weight is 51.3 kDa and the accession number is P02649.
TMPK-00639	Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) GCAP,ALP-1,Alkaline Phosphatase,ALPPL2,PLAP-like,ALPPL,A...	Rat	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His) is expressed in HEK293...
TMPK-00804	Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) GCAP,Alkaline Phosphatase,PLAP-like,Alkaline phosphatase, pl...	Human	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc) is expressed in HEK2...
TMPK-00855	Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) Alkaline Phosphatase,Alppl2,Akp5,Alpg,Alkaline phos...	Mouse	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His) is expressed in HEK2...
TMPK-00802	Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) GCAP,ALPPL,Alkaline phosphatase, placental-like,Alkaline Pho...	Human	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc) is expressed in HEK2...
TMPK-00801	Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated ALPPL2,PLAP-like,GCAP,ALPG,Alkaline phosphatase, pl...	Human	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated ...
TMPK-00803	Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) ALPG,ALPPL,Alkaline phosphatase, placental-like,Alk...	Human	HEK293 Cells
	Alkaline phosphatase can be considered "our favorite enzyme" for reasons apparent to those who diagnose and treat metabolic bone diseases or who study skeletal biology. Few might know, however, that alkaline phosphatase likely represents the most frequently assayed enzyme in all of medicine. Elevated activity in the circulation is universally recognized as a marker for skeletal or hepatobiliary disease. Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His) is expressed in HEK2...

重组蛋白

Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx)

Cat.No: TMPY-05297

Species: Human

Expression System: E. coli

Apolipoprotein E/APOE3 Protein, Human, Recombinant (His & Trx), Biotinylated

Cat.No: TMPY-05528

Species: Human

Expression System: E. coli

Alkaline Phosphatase (Germ type) /ALPG Protein, Rat, Recombinant (His)

Cat.No: TMPK-00639

Species: Rat

Expression System: HEK293 Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (mFc)

Cat.No: TMPK-00804

Species: Human

Expression System: HEK293 Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Mouse, Recombinant (His)

Cat.No: TMPK-00855

Species: Mouse

Expression System: HEK293 Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (hFc)

Cat.No: TMPK-00802

Species: Human

Expression System: HEK293 Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00801

Species: Human

Expression System: HEK293 Cells

Alkaline Phosphatase (Germ type) /ALPG Protein, Human, Recombinant (His)

Cat.No: TMPK-00803

Species: Human

Expression System: HEK293 Cells

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