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51

抑制剂 & 化合物

14

天然产物

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Cat. No. Product Name Target Signaling Pathways
T20365 Monopotassium glutamate

L-谷氨酸钾盐,Potassium glutamate,Potassium L-glutamate

Others Others
Monopotassium glutamate (Potassium glutamate) 可在食品中用作增味剂。
T72460 Dimethyl L-glutamate

Dimethyl glutamate

Dimethyl L-glutamate (Dimethyl glutamate), 一种可透膜的谷氨酸类似物,可刺激葡萄糖诱导的胰岛素 (insulin) 释放。Dimethyl L-glutamate 抑制KATP 通道的活性。Dimethyl L-glutamate 抑制E. gracilis 生长并导致细胞异常分裂。Dimethyl L-glutamate 可用于糖尿病、葡萄糖转运、磷酸化和进一步代谢的研究。
T21053 L-Lysine L-glutamate

L-Lysine L-glutamate is a bioactive chemical.
T33911 PENB-L-Glutamate

PENB-L-Glutamate is a caged glutamate.
T40973 MDNI-caged-L-glutamate

MDNI-caged-L-glutamate,MDNI-glu

MDNI-glu is a photosensitive derivative of L-glutamate, a major excitatory amino acid, that is biologically inert. It demonstrates improved utilization of incident light.
T35369 L(+)-Monosodium glutamate monohydrate

L(+)-Monosodium glutamate monohydrate,MSG monohydrate,L-Glutamic acid monosodium salt monohydrate,Monosodium L-glutamate monohydrate

Others Others
L(+)-Monosodium glutamate monohydrate (MSG monohydrate, L-Glutamic acid monosodium salt monohydrate, Monosodium L-glutamate monohydrate, Monosodium L-glutamate monohydrate)是一种广泛使用的营养添加剂和调味剂。L(+)-Monosodium glutamate monohydrate 可导致氧化应激介导的 DNA 损伤和细胞凋亡。
T23013 MNI-caged-L-glutamate

Others Others
rapidly and efficiently releases glutamate
T20362 Glutamyl-glutamic acid

Glu-glu,Dipotassium glutamyl-glutamate,N-L-alpha-Glutamyl-L-glutamic acid

Amino Acids and Derivatives Metabolism
Glutamyl-glutamic acid (Glu-glu) 是一些微球菌和节杆菌属菌的胞壁中的肽桥。
T41301 L-Cysteinesulfinic acid monohydrate

GluR Neuroscience
L-Cysteinesulfinic acid monohydrate 是代谢型谷氨酸受体 (mGluRs) 的有效激动剂,可以作用于 mGluR1,mGluR2,mGluR5,mGluR4,mGluR6 和 mGluR8,pEC50分别为 3.92,3.9,4.6,2.7,4.0,和 3.94。
T6022 LY404039

pomaglumetad

Glucocorticoid Receptor; GluR Endocrinology/Hormones; Neuroscience
LY404039 (pomaglumetad) 是可口服的mGluR2和mGluR3选择性激动剂,有抗精神病和抗焦虑的作用。它对重组人mGluR2和mGluR3的Ki 分别为 149 和 92 nM,比对其他受体/转运蛋白的抑制性高 100 倍以上。
T40376 L-Phenylalanine-15N

L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N

Calcium Channel Membrane transporter/Ion channel; Metabolism
L-Phenylalanine-15N ((S)-2-Amino-3-phenylpropionic acid-15N) 是 15N 标记的 L-Phenylalanine。L-Phenylalanine 是从大肠杆菌中分离出来的一种必需氨基酸。 L-Phenylalanine 广泛用于食品香精和药物的生产。
T1909 L-701324

7-氯-4-羟基-3-(3-苯氧基)苯基-2(1H)-喹啉,L701324

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
L-701324 是一种 NMDA 受体,对甘氨酸位点具有高亲和力和选择性,用作口服活性和长效抗惊厥药。
T34677 Sodium palmitoyl glutamate

Sodium N-palmitoyl-L-glutamate,Monosodium N-palmitoyl-L-glutamate

Sodium palmitoyl glutamate is a amino acid.
T16801 (RS)-(Tetrazol-5-yl)glycine

LY 285265,D,L-(tetrazol-5-yl)glycine

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
(RS)-(Tetrazol-5-yl)glycine (LY 285265) 是一种高效且选择性的 N-甲基-D-天冬氨酸 (NMDA) 受体激动剂。它能够诱导小鼠癫痫发作反应和 Fos。它对 GluN1/GluN2D 和 GluN1/GluN2A 的EC50分别为 99 nM,1.7 μM。
T2A2497L Glutamic acid diethyl ester

L-Glutamate diethylester,Diethyl glutamate,Glutamyl diethyl ester

Glutamic acid diethyl ester is a glutamic acid antagonist.
T66113 1-Methyl L-Glutamate

1-Methyl L-Glutamate 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66113,CAS号为 6384-08-3。
T20264 Ala-Glu-OH

L-Glutamic acid, N-L-alanyl-,Alanine glutamate,Alanylglutamic acid

Alanine glutamate is an agent of the dipeptide.
T30691 Calcium diglutamate

Calcium di-L-glutamate,Glutamic acid, calcium salt (2:1), L-

Calcium diglutamate(CDG), calcium acid salt of glutamic acid. As a soluble source of calcium ions, this chemical is used as a first-aid treatment for exposure to hydrofluoric acid.
T60112 H-Glu(OEt)-OEt.HCl

Diethyl L-glutamate hydrochloride,(S)-Diethyl 2-aminopentanedioate hydrochloride,L-谷氨酸二乙酯盐酸盐,Diethyl glutamate hydrochloride

Amino Acids and Derivatives Metabolism
H-Glu(OEt)-OEt.HCl (Diethyl L-glutamate hydrochloride) 是一种谷氨酸衍生物。
T31518 Dipinacoline glutamate

L-Glutamic acid dipinacoline ester,DiPG

Dipinacoline glutamate is a bioactive chemical.
T31497 Dineopentyl glutamate

L-Glutamic acid bis(2,2-dimethylpropyl) ester,DNPE

Dineopentyl glutamate is a bioactive chemical.
T34676 Sodium oleoyl glutamate

N-Oleoyl-L-glutamic acid monosodium salt,Acylglutamate OS-11

Sodium oleoyl glutamate is a sodium salt oleoyl glutamate.
T15684 L-689560

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
L-689560 是 N-甲基-D-天冬氨酸受体(NMDA)的有效拮抗剂,抑制 NMDA 甘氨酸结合位点。它用于研究 NMDA 受体在正常神经系统过程以及疾病中的作用,也广泛用作结合研究中的放射性标记配体,也。
T16800 (RS)-AMPA

(±)-AMPA

iGluR Membrane transporter/Ion channel; Neuroscience
(RS)-AMPA ((±)-AMPA) 是谷氨酸的一种类似物,对兴奋性神经递质 L-谷氨酸有激动作用。它不会干扰海藻酸或 NMDA 受体的结合位点。
T31742 Factor 390 A

F390-A,F390A,P-5-(S)-N-(N-(1-Oxo-2-(phosphonooxy)propyl)-L-gamma-glutamyl)-L-glutamate,F390 A

Factor 390 A is a phosphodiester between AMP & methanogen factor 420.
T74875 1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate

1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate 是脂质化合物,主要用于提高磷脂囊泡包封蛋白质的效率。
T7507 γ-L-Glutamyl-L-alanine

Others; Endogenous Metabolite Metabolism; Others
γ-L-Glutamyl-L-alanine 由γ-谷氨酸和丙氨酸组成,是CRF21(γ-谷氨酰环转移酶,GGCT)的底物。
TN7044 S-(4-Hydroxybenzyl)glutathione

GluR Neuroscience
L-γ-Glutamyl-S-[(4-hydroxyphenyl)methyl] 是一种谷胱甘肽衍生物,能够抑制红藻氨酸与脑谷氨酸受体的体外结合(IC50:2 μM)。
T0313 Evans blue

Direct Blue 53,C.I. 23860,伊文思蓝

GluR Neuroscience
Evans blue (C.I. 23860) 是一种突触泡谷氨酸吸收的有效抑制剂,同时也是一种AMPA/kainate 受体拮抗剂。
T9085 JFD01307SC

[(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]

Antibacterial Microbiology/Virology
JFD01307SC ([(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]) 是一种谷氨酰胺合成酶抑制剂。 它是抗结核剂,可作为 L-谷氨酸盐的模拟物,靶向参与谷氨酰胺生物合成的酶。
T22043 BCATc Inhibitor 2

Others Others
BCATc Inhibitor 2 是选择性分支链氨基转移酶抑制剂,可用于神经退行性疾病的研究。能够抑制 rBCATc (IC50:0.2 μM),hBCATc (IC50:0.8 μM)、 rBCATm (IC50:3.0 μM)。其中BCATc 也称为 BCAT1,存在于细胞质基质中的亚型。
T37190 L-Allylglycine

Dehydrogenase; GABA Receptor Membrane transporter/Ion channel; Metabolism; Neuroscience
L-Allylglycine 是 GABA 合成酶(谷氨酸脱羧酶)的有效抑制剂。
T22722 Dihydrokainic acid

Others Others
EAAT2(GLT1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
T12118 MSOP

GluR Neuroscience
MSOP is a selective antagonist of group III metabotropic glutamate receptor (KD of 51 μM for the L-AP4-sensitive presynaptic mGluR).
T60645 Glutamate-5-kinase-IN-2

Glutamate-5-kinase-IN-2 (compound 54) 通过促进 L-谷氨酸结合位点的构象变化,从而抑制 G5K 活性,它是谷氨酸 5-激酶 (G5K)的有效抑制剂,MIC 为 4.2 μM。Glutamate-5-kinase-IN-2 具有用于抗结核药物研究的潜力。
T39830 L-AP3

3-Phosphono-L-alanine,L-AP3

L-AP3 is a potent antagonist of metabotropic glutamate receptor (mGluR), demonstrating inhibitory effects on D-phosphoserine and L-phosphoserine with IC50 values of 368 μM and 2087 μM, respectively.
T78350 Glutamate dehydrogenase

Glutamate dehydrogenase为存在于原核生物与真核生物线粒体中的酶类,适用于氨、α-酮戊二酸、L-谷氨酸及脲酶的酶促反应检测。
T23930 Cysteic acid, L-

NSC254030,L-Cysteic acid,Cysteinic acid,NSC 254030,NSC-254030

L-Cysteic acid is a useful agonist at several rat metabotropic glutamate receptors. L-Cysteic acid is an analogue of cysteine sulfinic acid, may be used in studies of excitatory amino acids in the brain.
T78364 Alanine aminotransferase

Endogenous Metabolite Metabolism
Alanine aminotransferase是一种酶,能促进L-丙氨酸与2-氧代谷氨酸之间可逆的转化为丙酮酸和L-谷氨酸。
T39565 L-Glutamic acid-15N

L-Glutamic acid-15N is the 15N-labeled version of L-Glutamic acid, an excitatory neurotransmitter and an agonist at metabotropic, kainate, NMDA, and AMPA glutamate receptor subtypes. It directly activates the release of dopamine (DA) from dopaminergic terminals.
T24917 UBP684

UBP-684,UBP 684

UBP684 is an NMDAR pan-PAM. UBP684 increases the maximal l-glutamate/glycine response while having minor subunit-specific effects on agonist potency. It robustly potentiates responses at all GluN1/GluN2 subtypes and at neuronal NMDARs.
T25717 L-Ibotenic acid

Ibotenic acid, L-

L-Ibotenic acid is a chemical compound and psychoactive drug which occurs naturally in Amanita muscaria and related species of mushrooms typically found in the temperate and boreal regions of the northern hemisphere. It is a conformationally-restricted an
T60344 L-Cytidine

L-Cytidine 是Cytidine 的 L-构型形式。L-Cytidine 是一种嘧啶核苷,是RNA 的组成部分。Cytidine 可控制神经胶质谷氨酸循环,影响脑磷脂代谢,儿茶酚胺的合成和线粒体功能。
T60242 (RS)-AMPA monohydrate

(RS)-AMPA ((±)-AMPA) monohydrate 是谷氨酸的一种类似物,对兴奋性神经递质 L-谷氨酸 (L-glutamic acid) 有激动作用。(RS)-AMPA monohydrate 不会干扰海藻酸或 NMDA 受体的结合位点。
T3011L Kynurenine sulfate monohydrate

L-Kynurenine sulfate monohydrate

Kynurenine sulfate monohydrate is a precursor of kynurenic acid which is the only recognized endogenous excitatory amino acid receptor antagonist agent in the central nervous system. L-Kyn is known to be a pigment generating component in animals. In mamma
T7720 CGP 37849

CGP-37849,CGP37849

NMDAR; iGluR Membrane transporter/Ion channel; Neuroscience
CGP 37849 是一种竞争性口服活性 N-甲基-D-天冬氨酸 (NMDA) 受体拮抗剂((Ki = 35 nM)),具有有效性。CGP 37849 是啮齿动物的抗惊厥药,也具有抗抑郁和抗焦虑的特性。
T71305 Clofibric Acid-d4

Clofibric acid-d4 is intended for use as an internal standard for the quantification of clofibric acid by GC- or LC-MS. Clofibric acid is a peroxisome proliferator-activated receptor α (PPARα) agonist (EC50 = 50 µM in a transactivation assay) and the active metabolite of clofibrate. It is formed from clofibrate by tissue and serum esterases. Dietary administration of clofibric acid (0.067-0.22%) reduces serum cholesterol, phospholipid, and triglyceride levels in rats. It decreases glutamate oxal...
T37127 L-AP4 monohydrate

L-AP4 monohydrate

L-AP4 (L-APB) monohydrate is a potent and specific agonist for the group III mGluRs, with EC50s of 0.13, 0.29, 1.0, 249 μM for mGlu4, mGlu8, mGlu6 and mGlu7 receptors, respectively[1][2]. L-AP4 (5-30 μg, intrathecal inhection 4-5 days) significantly increases the paw withdrawal threshold in response to application of von Frey filaments in eight nerve-ligated rats in a dose-dependent manner. Intrathecal administration of different doses of L-AP4 is not associated with any evident motor dysfunctio...
T77217 Saccharopine hydrochloride

Saccharopine hydrochloride(L-Saccharopine hydrochloride)是赖氨酸降解的中间体,兼具线粒体毒性。该化合物由赖氨酸-酮戊二酸还原酶催化赖氨酸与α-酮戊二酸生成。继而,糖精脱氢酶作用于Saccharopine hydrochloride,生成α-氨基己酸酯半醛和谷氨酸。其通过干扰线粒体的稳态平衡,对生物体的发育造成损害。
T75793 ω-Agatoxin IVA TFA

ω-Agatoxin IVA TFA 是一种高效的针对P/Q型Ca2+(Cav2.1)通道的选择性阻滞剂,IC50对P型为2 nM,对Q型为90 nM。此化合物能够抑制高钾条件下的谷氨酸释放和钙流入,IC50在30-225 nM范围。同时,ω-Agatoxin IVA TFA阻断高钾诱发的5-羟色胺及去甲肾上腺素释放,但不影响L型或N型Ca2+通道。

化合物

Monopotassium glutamate
Cat.No: T20365
Synonym: L-谷氨酸钾盐,Potassium glutamate,Potassium L-glutamate
Target: Others
Dimethyl L-glutamate
Cat.No: T72460
Synonym: Dimethyl glutamate
Target:
L-Lysine L-glutamate
Cat.No: T21053
Synonym:
Target:
PENB-L-Glutamate
Cat.No: T33911
Synonym:
Target:
MDNI-caged-L-glutamate
Cat.No: T40973
Synonym: MDNI-caged-L-glutamate,MDNI-glu
Target:
L(+)-Monosodium glutamate monohydrate
Cat.No: T35369
Synonym: L(+)-Monosodium glutamate monohydrate,MSG monohydrate,L-Glutamic acid monosodium salt monohydrate,Monosodium L-glutamate monohydrate
Target: Others
MNI-caged-L-glutamate
Cat.No: T23013
Synonym:
Target: Others
Glutamyl-glutamic acid
Cat.No: T20362
Synonym: Glu-glu,Dipotassium glutamyl-glutamate,N-L-alpha-Glutamyl-L-glutamic acid
Target: Amino Acids and Derivatives
L-Cysteinesulfinic acid monohydrate
Cat.No: T41301
Synonym:
Target: GluR
LY404039
Cat.No: T6022
Synonym: pomaglumetad
Target: Glucocorticoid Receptor, GluR
L-Phenylalanine-15N
Cat.No: T40376
Synonym: L-苯丙氨酸 15N,(S)-2-Amino-3-phenylpropionic acid-15N,L-Phenylalanine-15N
Target: Calcium Channel
L-701324
Cat.No: T1909
Synonym: 7-氯-4-羟基-3-(3-苯氧基)苯基-2(1H)-喹啉,L701324
Target: NMDAR, iGluR
Sodium palmitoyl glutamate
Cat.No: T34677
Synonym: Sodium N-palmitoyl-L-glutamate,Monosodium N-palmitoyl-L-glutamate
Target:
(RS)-(Tetrazol-5-yl)glycine
Cat.No: T16801
Synonym: LY 285265,D,L-(tetrazol-5-yl)glycine
Target: NMDAR, iGluR
Glutamic acid diethyl ester
Cat.No: T2A2497L
Synonym: L-Glutamate diethylester,Diethyl glutamate,Glutamyl diethyl ester
Target:
1-Methyl L-Glutamate
Cat.No: T66113
Synonym:
Target:
Ala-Glu-OH
Cat.No: T20264
Synonym: L-Glutamic acid, N-L-alanyl-,Alanine glutamate,Alanylglutamic acid
Target:
Calcium diglutamate
Cat.No: T30691
Synonym: Calcium di-L-glutamate,Glutamic acid, calcium salt (2:1), L-
Target:
H-Glu(OEt)-OEt.HCl
Cat.No: T60112
Synonym: Diethyl L-glutamate hydrochloride,(S)-Diethyl 2-aminopentanedioate hydrochloride,L-谷氨酸二乙酯盐酸盐,Diethyl glutamate hydrochloride
Target: Amino Acids and Derivatives
Dipinacoline glutamate
Cat.No: T31518
Synonym: L-Glutamic acid dipinacoline ester,DiPG
Target:
Dineopentyl glutamate
Cat.No: T31497
Synonym: L-Glutamic acid bis(2,2-dimethylpropyl) ester,DNPE
Target:
Sodium oleoyl glutamate
Cat.No: T34676
Synonym: N-Oleoyl-L-glutamic acid monosodium salt,Acylglutamate OS-11
Target:
L-689560
Cat.No: T15684
Synonym:
Target: NMDAR, iGluR
(RS)-AMPA
Cat.No: T16800
Synonym: (±)-AMPA
Target: iGluR
Factor 390 A
Cat.No: T31742
Synonym: F390-A,F390A,P-5-(S)-N-(N-(1-Oxo-2-(phosphonooxy)propyl)-L-gamma-glutamyl)-L-glutamate,F390 A
Target:
1,5-Dihexadecyl N-(3-carboxy-1-oxopropyl)-L-glutamate
Cat.No: T74875
Synonym:
Target:
γ-L-Glutamyl-L-alanine
Cat.No: T7507
Synonym:
Target: Others, Endogenous Metabolite
S-(4-Hydroxybenzyl)glutathione
Cat.No: TN7044
Synonym:
Target: GluR
Evans blue
Cat.No: T0313
Synonym: Direct Blue 53,C.I. 23860,伊文思蓝
Target: GluR
JFD01307SC
Cat.No: T9085
Synonym: [(1,1-DIOXIDOTETRAHYDROTHIEN-3-YL)AMINO]
Target: Antibacterial
BCATc Inhibitor 2
Cat.No: T22043
Synonym:
Target: Others
L-Allylglycine
Cat.No: T37190
Synonym:
Target: Dehydrogenase, GABA Receptor
Dihydrokainic acid
Cat.No: T22722
Synonym:
Target: Others
MSOP
Cat.No: T12118
Synonym:
Target: GluR
Glutamate-5-kinase-IN-2
Cat.No: T60645
Synonym:
Target:
L-AP3
Cat.No: T39830
Synonym: 3-Phosphono-L-alanine,L-AP3
Target:
Glutamate dehydrogenase
Cat.No: T78350
Synonym:
Target:
Cysteic acid, L-
Cat.No: T23930
Synonym: NSC254030,L-Cysteic acid,Cysteinic acid,NSC 254030,NSC-254030
Target:
Alanine aminotransferase
Cat.No: T78364
Synonym:
Target: Endogenous Metabolite
L-Glutamic acid-15N
Cat.No: T39565
Synonym:
Target:
UBP684
Cat.No: T24917
Synonym: UBP-684,UBP 684
Target:
L-Ibotenic acid
Cat.No: T25717
Synonym: Ibotenic acid, L-
Target:
L-Cytidine
Cat.No: T60344
Synonym:
Target:
(RS)-AMPA monohydrate
Cat.No: T60242
Synonym:
Target:
Kynurenine sulfate monohydrate
Cat.No: T3011L
Synonym: L-Kynurenine sulfate monohydrate
Target:
CGP 37849
Cat.No: T7720
Synonym: CGP-37849,CGP37849
Target: NMDAR, iGluR
Clofibric Acid-d4
Cat.No: T71305
Synonym:
Target:
L-AP4 monohydrate
Cat.No: T37127
Synonym: L-AP4 monohydrate
Target:
Saccharopine hydrochloride
Cat.No: T77217
Synonym:
Target:
ω-Agatoxin IVA TFA
Cat.No: T75793
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T6871 L-Glutamic acid monosodium salt

Monosodium glutamate,谷氨酸单钠盐,Glutacyl,Glutavene,L-谷氨酸单钠盐,Ajinomoto,MSG

Apoptosis; Ferroptosis; GluR; iGluR Apoptosis; Membrane transporter/Ion channel; Neuroscience
L-Glutamic acid monosodium salt (MSG) 作为兴奋性氨基酸神经递质,是谷氨酸盐受体所有亚型的激动剂,对多巴胺从神经末梢释放的过程有激动作用。
T0326L L-Glutamine

L-Glutamic acid 5-amide,L-谷氨酰胺

Ferroptosis; Endogenous Metabolite; GluR Apoptosis; Metabolism; Neuroscience
L-Glutamine (L-Glutamic acid 5-amide) 是在人体中大量存在的一种非必需氨基酸,由谷氨酸和氨合成。它为某些细胞中的氧化提供了碳源。
T20191 (-)-Camphoric acid

(-)-樟脑酸,L-Camphoric acid,Camphoric acid, (-)-

GluR Neuroscience
(-)-Camphoric acid (L-Camphoric acid) 是一种活性较低的樟脑酸对映异构体,樟脑酸可诱导 GluR 表达。
T1324 O-Phospho-L-serine

L-Serine O-phosphate,磷酸化丝氨酸,Phosphoserine,Dexfosfoserine,L-SOP

Amino Acids and Derivatives; Endogenous Metabolite; GluR; NMDAR Metabolism; Neuroscience
O-Phospho-L-serine (Phosphoserine) 是 L-serine 合成过程中的直接前体物质,是 mGluR 激动剂。
T2A2497 L-Glutamic acid

谷氨酸,(S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,L-谷氨酸,glutacid,Glutaminol

Apoptosis; Ferroptosis; Endogenous Metabolite; iGluR Apoptosis; Membrane transporter/Ion channel; Metabolism; Neuroscience
L-Glutamic acid (Glutaminol) 作为一种兴奋性氨基酸神经递质,为谷氨酸盐受体所有亚型的激动剂,对多巴胺从神经末梢释放的过程有激动作用。
T3377 L-Phenylalanine

L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine

Calcium Channel; Endogenous Metabolite; iGluR Membrane transporter/Ion channel; Metabolism; Neuroscience
L-Phenylalanine (3-Phenyl-L-alanine) 是分离自大肠杆菌的必需氨基酸,是 NMDARs(KB573 μM) 和非 NMDARs 的甘氨酸和谷氨酸结合位点的竞争性拮抗剂,用于食品香料和药品的生产中。它是一种电压依赖性 α2δ 亚基 Ca2+通道拮抗剂,Ki 为 980 nM。
T4885 (-)-Aspartic acid

(R)-Aspartic acid,Asp,D-(-)-Aspartic acid,D-天门冬氨酸,Aminosuccinic acid,asparagic acid,L-Homoproline,D-Aspartic acid

Endogenous Metabolite; NMDAR; iGluR Membrane transporter/Ion channel; Metabolism; Neuroscience
(-)-Aspartic acid (L-Homoproline) 是一种存在于无脊椎动物和脊椎动物中的内源性氨基酸,是 NMDA 受体激动剂,可调节睾酮合成。
T4913 Maleic acid

Endogenous Metabolite; Antibacterial Metabolism; Microbiology/Virology
Maleic Acid 是大肠杆菌和单核细胞增生李斯特菌的谷氨酸脱羧酶抑制剂。
T4813 L-Citrulline

Endogenous Metabolite Metabolism
L-Citrulline 是一种氨基酸,源自于精氨酸-瓜氨酸途径获得的 l-精氨酸,或脯氨酸、谷氨酰胺和谷氨酸盐的分解代谢过程中产生的鸟氨酸。
T5267 N-Acetyl-L-glutamic acid

Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-glutamic acid (Ac-L-Glu-OH) 是一种 N-Acyl-L-氨基酸,是动物细胞培养基的组成成分,是一种酿酒酵母和人类的代谢物。
T5083 L-Cysteic acid monohydrate

L-磺基丙氨酸 一水合物,3-Sulfo-L-alanine Monohydrate

Endogenous Metabolite; GluR Metabolism; Neuroscience
L-Cysteic acid monohydrate (3-Sulfo-L-alanine Monohydrate) 是内源性代谢产物的一种。
T5287 N-Acetyl-L-aspartic acid

AC-ASP-OH,N-Acetylaspartic acid,N-乙酰-L-天门冬氨酸

Others; Endogenous Metabolite Metabolism; Others
N-Acetyl-L-aspartic acid (AC-ASP-OH) 是天冬氨酸的衍生物, 是由氨基酸天冬氨酸和乙酰辅酶 A 在神经元中合成的。
T11803 L-Cysteinesulfinic acid

Others Others
L-Cysteinesulfinic acid is a potent agonist at several rat metabotropic glutamate receptors (mGluRs, pEC50s of 3.92±0.03, 4.6±0.2, 3.9±0.2, 2.7±0.2, 4.0±0.2, and 3.94±0.08 for mGluR1, mGluR5, mGluR2, mGluR4, mGluR6, and mGluR8, respectively).
TN6515 Selaginellin

Selaginellin has a neuroprotective effect against L-glutamate-induced neurotoxicity through mechanisms related to anti-oxidation and anti-apoptosis via scavenging reactive oxygen species and up-regulating the expression of klotho gene. Selaginellin shows

天然产物

L-Glutamic acid monosodium salt
Cat.No: T6871
Synonym: Monosodium glutamate,谷氨酸单钠盐,Glutacyl,Glutavene,L-谷氨酸单钠盐,Ajinomoto,MSG
Target: Apoptosis, Ferroptosis, GluR, iGluR
L-Glutamine
Cat.No: T0326L
Synonym: L-Glutamic acid 5-amide,L-谷氨酰胺
Target: Ferroptosis, Endogenous Metabolite, GluR
(-)-Camphoric acid
Cat.No: T20191
Synonym: (-)-樟脑酸,L-Camphoric acid,Camphoric acid, (-)-
Target: GluR
O-Phospho-L-serine
Cat.No: T1324
Synonym: L-Serine O-phosphate,磷酸化丝氨酸,Phosphoserine,Dexfosfoserine,L-SOP
Target: Amino Acids and Derivatives, Endogenous Metabolite, GluR, NMDAR
L-Glutamic acid
Cat.No: T2A2497
Synonym: 谷氨酸,(S)-Glutamic acid,glutamic acid,(+)-L-Glutamic acid,Aciglut,L-谷氨酸,glutacid,Glutaminol
Target: Apoptosis, Ferroptosis, Endogenous Metabolite, iGluR
L-Phenylalanine
Cat.No: T3377
Synonym: L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine
Target: Calcium Channel, Endogenous Metabolite, iGluR
(-)-Aspartic acid
Cat.No: T4885
Synonym: (R)-Aspartic acid,Asp,D-(-)-Aspartic acid,D-天门冬氨酸,Aminosuccinic acid,asparagic acid,L-Homoproline,D-Aspartic acid
Target: Endogenous Metabolite, NMDAR, iGluR
Maleic acid
Cat.No: T4913
Synonym:
Target: Endogenous Metabolite, Antibacterial
L-Citrulline
Cat.No: T4813
Synonym:
Target: Endogenous Metabolite
N-Acetyl-L-glutamic acid
Cat.No: T5267
Synonym: Ac-L-Glu-OH,N-乙酰-L-谷氨酰胺,N-Acetylglutamic acid
Target: Others, Endogenous Metabolite
L-Cysteic acid monohydrate
Cat.No: T5083
Synonym: L-磺基丙氨酸 一水合物,3-Sulfo-L-alanine Monohydrate
Target: Endogenous Metabolite, GluR
N-Acetyl-L-aspartic acid
Cat.No: T5287
Synonym: AC-ASP-OH,N-Acetylaspartic acid,N-乙酰-L-天门冬氨酸
Target: Others, Endogenous Metabolite
L-Cysteinesulfinic acid
Cat.No: T11803
Synonym:
Target: Others
Selaginellin
Cat.No: TN6515
Synonym:
Target:
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