25
18
1739
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6019 |
Volasertib
BI 6727,伏拉塞替 |
Apoptosis; PLK | Apoptosis; Cell Cycle/Checkpoint |
Volasertib (BI 6727) 是一种具有口服活性的高效ATP 竞争性Polo 样激酶 1 抑制剂。它抑制 PLK2 和 PLK3,IC50分别为 5 和 56 nM。它是二氢蝶呤酮衍生物,有抗肿瘤活性,可诱导有丝分裂停滞和细胞凋亡。 | |||
T9975 |
GPR183
3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide |
Others | Others |
GPR183 (3-(3,4-difluorophenyl)-N-[3-fluoro-5-(morpholin-4-yl)phenyl]propanamide) 是一种趋化受体,在 B 细胞中具有成熟作用,其内源性配体是氧甾醇 7α,25-二羟基胆固醇 (7α,25-OHC)。 GPR183 可用于炎症性肠病 (IBD) 的研究。 | |||
T74258 | HL-8 | ||
HL-8 是一种靶向PI3K 激酶的PROTAC 分子。HL-8 在10 μM 浓度下 8 h 内对PI3K 激酶具有显着且完全的降解作用。HL-8 具有研究癌症疾病的潜力。 | |||
T36693 |
FD-211
|
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FD-211 is a δ lactone originally isolated from M. lutea with anticancer activity.1 It is cytotoxic to adriamycin-susceptible P388, T-24, HeLa, A549, and HL-60 cancer cells (IC50s = 4, 0.5, 1, 1, and 0.2 μg/ml, respectively), as well as adriamycin-resistant HL-60/ADR cells (IC50 = 0.1 μg/ml). FD-211 also inhibits DNA, RNA, and protein synthesis in HeLa cells (IC50 = 1.25 μg/ml for all). |1. Nozawa, O., Okazaki, T., Sakai, N., et al. A novel bioactive δ lactone FD-211. Taxonomy, isolation and char... | |||
T78978 |
Antitrypanosomal agent 13
|
Parasite | Microbiology/Virology |
Antitrypanosomal agent 13 (compound 4b) 是一种高效的抗锥虫剂,具备显著的杀锥虫活性和细胞毒性。针对 T. brucei 和 HL-60,Antitrypanosomal agent 13 的 GI50 值分别为 0.18 μM 和 8.4 μM。 | |||
T60748 |
ZDWX-25
|
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ZDWX-25 是 GSK-3β和 DYRK1A 的高效双重抑制剂,它对 SH-SY5Y 和 HL-7702 细胞显示出显著的细胞毒性。ZDWX-25 可用于研究阿尔茨海默症,其对 GSK-3β 的 IC50值为 71 nM。。 | |||
T13643 |
Demethoxydeacetoxypseudolaric acid B analog
脱甲氧基脱乙酰土槿皮乙酸,去甲氧基去乙酰氧基土槿甲酸B类似物 |
Others | Others |
Demethoxydeacetoxypseudolaric acid B analog 是由 Pseudolaric acid B 半合成得到,能够有效抑制 HMEC-1、HL-60、A-549、MB-MDA-468、BEL-7402、HCT116、Hela 细胞,且 IC50值范围为 0.136-1.162 μM。 | |||
T36399 |
PAO-Nap
|
||
PAO-Nap is a chemically modified version of PAO, in which a naphthalimide fluorophore is attached to the compound using a linker called aminocaproic acid. This modified compound, PAO-Nap, exhibits a selective targeting of thioredoxin reductase, leading to the induction of apoptosis in HL-60 cells through oxidative stress mechanisms[1]. | |||
T82774 |
Caspase-3 activator 3
|
Caspase | Apoptosis; Proteases/Proteasome |
Caspase-3 activator 3 (compound 2h) 通过激活caspase 3诱导HL-60和K562细胞apoptosis,表现出抗白血病活性。其对HL-60细胞的IC50值为42.89 μM,对K562细胞的IC50值为33.61 μM。 | |||
T78815 |
MOZ-IN-3
|
Histone Acetyltransferase | Chromatin/Epigenetic |
MOZ-IN-3 (Compound 6j) 是KAT6A (MOZ) 乙酰转移酶的抑制剂,IC50值为30 nM。该化合物在四种髓系白血病细胞系(HL-60、U937、SKNO-1、K562)上展现了抗肿瘤活性,并且显示出良好的代谢稳定性及药代动力学特性。 | |||
T77041 | Iratumumab | ||
Iratumumab (MDX-060),一种人来源IgG1κ型CD30单克隆抗体,能够抑制表达CD30的肿瘤细胞生长。适用于霍奇金淋巴瘤(HL)与间变性大细胞淋巴瘤(ALCL)的研究。 | |||
T36593 |
TEI-9648
|
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TEI-9648, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9648 has the potential for bone metabolism research[1][2]. TEI-9648 (10-1000 nM) dose-dependently blocks the reciprocal changes of CD11b and CD71 expression associated with HL-60 cell differentiation induced by 1α,25(OH)2D3[1]. TEI-9648 has cons... | |||
T61828 |
DNA-PK-IN-8
|
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DNA-PK-IN-8(化合物DK1)是一种高效、选择性且口服活性的DNA依赖蛋白激酶 (DNA-PK) 抑制剂,其IC50值为0.8 nM。与Doxorubicin联合应用时,该化合物能在多种癌细胞中展现出协同的抗增殖效应,并能显著地抑制HL-60肿瘤生长。 | |||
T82775 |
Caspase-3 activator 2
|
Caspase | Apoptosis; Proteases/Proteasome |
Caspase-3 activator 2 (Compound 2f) 是诱导细胞凋亡的caspase 3激活剂,适用于癌症研究。该化合物对 HL-60 细胞和 K562 细胞展示出细胞毒性,IC50 值分别为 33.52 μM 和 76.90 μM。 | |||
T83724 |
TPP-1 hydrochloride
Targeting PD-L1 Peptide |
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TPP-1是一种针对程序化细胞死亡蛋白1(PD-1)及其配体PD-1配体(PD-L1)之间蛋白-蛋白相互作用的肽抑制剂。它在无细胞实验中结合到PD-L1(Kd = 94.67 nM)。TPP-1 (20 µM)能逆转PD-L1在抗CD3激活的人类CD4+ T细胞中所引起的干扰素γ(IFN-γ)水平的下降。在使用HL-60白血病细胞与抗CD3激活的人类CD4+ T细胞共培养并在植入前预处理时,以4 mg/kg的剂量给药,可减少小鼠异种移植模型中的肿瘤体积。 | |||
T36418 |
O-Desmethyl-N-deschlorobenzoyl Indomethacin
|
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O-Desmethyl-N-deschlorobenzoyl indomethacin is a metabolite of the non-steroidal anti-inflammatory drug (NSAID) and COX inhibitor indomethacin .1It is formed from indomethacin in isolated rabbit hepatocytes. O-Desmethyl-N-deschlorobenzoyl indomethacin (600 μM) decreases the viability of HL-60 leukemia cells when cultured with glucose oxidase.2It has also been used in the synthesis of prostaglandin D2receptor antagonists.3 1.Evans, M.A., Papazafiratou, C., Bhat, R., et al.Indomethacin metabolism ... | |||
T36894 |
5-Bromouridine
|
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5-Bromouridine is a brominated analog of the nucleoside uridine .1It can be incorporated into RNA and subsequently detected by antibodies against bromodeoxyuridine .25-Bromouridine decreases the viability of HL-60 and MOLT-4 cells (LC50s = 10 and 20 μM, respectively). It induces apoptosis and halts the cell cycle at the S phase in HL-60 cells. It is photoreactive, and UV irradiation has been used to cross-link RNA containing 5-bromouridine to proteins in the study of of RNA-protein interactions.... | |||
T36864 |
GRP (human) (trifluoroacetate salt)
|
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Gastrin-releasing peptide (GRP) is a neuropeptide that stimulates gastrin release. It binds to (Ki = 300 nM) and stimulates amylase secretion in rat pancreatic AR42J cells (EC50 = 0.3 nM). GRP increases proliferation of human liver carcinoma HepG2 and MHCC97H cells but does not affect the proliferation of normal HL-7702 liver cells at a concentration of 1 nM. In vivo, GRP (0.35 nmol/kg/h) increases both pancreatic exocrine secretion and pancreatic polypeptide (PP) release in rats. It dose-depend... | |||
T76379 |
Myelopeptide-2
|
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Myelopeptide-2 分离于猪骨髓细胞培养上清,能够恢复 HL-60 白血病细胞或麻疹病毒条件抑制下人 T 淋巴细胞的丝裂原反应活性、白细胞介素-2 (IL-2) 合成水平和白细胞介素-2受体 (IL-2R) 表达水平。Myelopeptide-2 参与免疫稳态调节,在抗肿瘤和抗病毒研究中具有广阔的应用前景。 | |||
T38377 |
ADTL-EI1712
ADTL-EI1712 |
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ADTL-EI1712 is a dual inhibitor of ERK1 and ERK5 (IC50s = 40.43 and 64.5 nM, respectively).1It reduces ERK1 and ERK5 activity by 93.5% and 89.4%, respectively, but also inhibits ERK2 activity by 92.7%, in a panel of 100 kinases at 1 μM. ADTL-EI1712 inhibits proliferation of HL-60 and MKN74, but not HeLa, cancer cells (IC50s = 1.26, 2.55, and >50 μM, respectively). It reduces tumor growth and intratumor phosphorylation of ERK1/2 and ERK5 in an MKN74 mouse xenograft model when administered at a do... | |||
T37056 |
D-erythro-MAPP
|
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D-erythro-MAPP is a derivative of ceramide and an inhibitor of alkaline ceramidase (Ki = 2-13 μM; IC50 = 1-5 μM). It is selective for alkaline ceramidase over acid ceramidase (IC50 = >500 μM) as well as the serine/threonine protein phosphatase CAPP at concentrations up to 10 μM. D-erythro-MAPP increases intracellular ceramide levels, induces cell cycle arrest at the G0/G1 phase, and inhibits growth of HL-60 promyelocytic leukemia cells in a time- and concentration-dependent manner. | |||
T36035 |
CAY10784
|
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CAY10784 is a STAT3 inhibitor (IC50= 0.74 μM in a reporter assay) and a derivative of WP1066 .1It inhibits proliferation of HeLa, Caco-2, A549, A375, U87MG, and HL-60 cancer cells (IC50s = 1.8, 1.8, 3, 2.8, 2.3, and 1.2 μM, respectively) but not PC3 or HT-29 cancer cells (IC50s = >10 μM for both). CAY10784 is also active againstH. pyloriandC. jejuni(MICs = 1.6 and 4.7 μM, respectively).2 1.Lü, Z., Li, X., Li, K., et al.Structure-activity study of nitazoxanide derivatives as novel STAT3 pathway i... | |||
T35536 |
Tpl2 Kinase Inhibitor (hydrochloride)
|
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Tpl2 kinase inhibitor is an inhibitor of tumor progression locus 2 (Tpl2; IC50= 0.05 μM).1It is selective for Tpl2 over MEK, p38 MAPK, Src, MK2, and PKC (IC50s = >40, 180, >400, 110, and >400 μM, respectively). Tpl2 kinase inhibitor inhibits LPS-induced TNF-α production in isolated human monocytes and whole blood (IC50s = 0.7 and 8.5 μM, respectively). It enhances differentiation induced by calcitriol in HL-60 and U937 leukemia cells when used at a concentration of 5 μM.2Tpl2 kinase inhibitor (5... | |||
T35772 |
Emestrin
|
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Emestrin is a mycotoxin originally isolated from E. striata that has antimicrobial, immunomodulatory, and cytotoxic activities.1,2,3,4,5 It is active against the fungi C. albicans and C. neoformans, as well as the bacteria E. coli, S. aureus, and methicillin-resistant S. aureus (MRSA; IC50s = 3.94, 0.6, 2.21, 4.55, and 2.21 μg/ml, respectively).2 Emestrin is a chemokine (C-C motif) receptor 2 (CCR2) antagonist (IC50 = 5.4 μM in a radioligand binding assay using isolated human monocytes).3 Emestr... | |||
T36199 |
AZD 1152 (hydrochloride)
|
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AZD 1152 is an orally bioavailable prodrug of AZD 1152-HQPA, a selective inhibitor of Aurora kinase B (IC50= 0.36 nM).1AZD 1152 is converted to AZD 1152-HQPA in plasma. Inhibition of Aurora B results in disruption of spindle checkpoint functions and chromosome alignment, resulting in inhibition of cytokinesis followed by apoptosis.2,3AZD 1152 inhibits tumor xenograft growthin vivo.4,5 1.Mortlock, A.A., Foote, K.M., Heron, N.M., et al.Discovery, synthesis, and in vivo activity of a new class of p... |
Cat. No. | Product Name | Target | Signaling Pathways |
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TMS0484 |
Episyringaresinol 4'-O-β-D-glncopyranoside
(-)-丁香树脂酚-4-O-β-D-葡萄糖苷,(-)-Syringaresinol 4-O-β-D-glucopyranosi |
Others | Others |
Episyringaresinol 4'-O-β-D-glncopyranoside ((-)-Syringaresinol 4-O-β-D-glucopyranosi) 是一种天然的潜在神经炎症抑制剂,分离自鼠尾草 (Alhagi sparsifoliaShap) 。 | |||
T4601 |
9-Methoxycanthin-6-one
|
Others | Others |
9-Methoxycanthin-6-one 是存在于完整植株和不同外植体的愈伤组织中的 Canthin-6-one 生物碱,具有抗肿瘤作用。 | |||
T6S0234 |
Toosendanin
|
Others | Others |
Toosendanin 是一种从杜鹃花果实皮中提取的三萜,具有杀虫和抗炎活性,可用于研究缓解疼痛。 | |||
T3S0057 |
Dihydrochelerythrine
12,13-Dihydrochelerythrine,二氢白屈菜红碱 |
Antifungal | Microbiology/Virology |
Dihydrochelerythrine (12,13-Dihydrochelerythrine) 是一种从榕树叶片分离出的天然化合物,具有抗真菌活性,有潜力治疗多丝蚴引起的严重感染。 | |||
T2S2215 |
Crebanine
|
Apoptosis; Others; Akt | Apoptosis; Cytoskeletal Signaling; Others; PI3K/Akt/mTOR signaling |
Crebanine 是来自于韦诺萨千金藤的一种生物碱,通过抑制 MAPKs 和 Akt 信号通路表现出抗炎活性,还具有抗心律失常的作用。它可诱导人类癌细胞的 G1阻滞和凋亡。 | |||
TN5373 |
Ustusolate A
|
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1. Ustusolate A shows weak cytotoxicity against HL-60 and A549 cells with IC50 values of 20.6 and 30.0 microM, respectively. | |||
TN4373 |
Kaempferol tetraacetate
|
Antifection | Microbiology/Virology |
Kaempferol tetraacetate is a potent antiplatelet agent. It exhibits significant cytotoxicity in vitro against three human cell lines HL-60, U937 and SK-MEL-1. | |||
T81529 |
Peganumine A
|
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Peganumine A,一种天然产物,源自Peganum harmala,具备对HL-60、MCF-7、PC-3、HepG2细胞线显示出细胞毒性作用,其IC50值依次为5.8、38.5、40.2、55.4 µM[1]< /sup>。 | |||
TN5593 |
Euphohelioscopin A
|
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Euphohelioscopin A, an activator of protein kinase C (PKC), it inhibits proliferation and induces differentiation of the myeloid leukemia cell lines THP-1 and HL-60. Euphohelioscopin A has anti-inflammary activity, it exhibits moderate inhibitory activity | |||
T81937 |
Lewis a trisaccharide
Lewis a |
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Lewis a trisaccharide 是精子聚糖结构和 HL-60 细胞表面聚糖结构的主要组分。 | |||
T83260 |
6β,7β-Epoxyasteriscunolide A
|
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6β,7β-Epoxyasteriscunolide A 是一种具有细胞毒性的倍半萜类化合物,其对 HL-60 和 MOLT-3 白血病细胞系展现出的 IC50 值介于 4.1-5.4 μM 之间。 | |||
T82741 |
Changnanic acid
|
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Changnanic acid(五味子酸)是一种具有潜在抗肿瘤活性的三萜化合物。在Bel-7402、MCF-7和HL-60人类肿瘤细胞系中,Changnanic acid展现了中等水平的细胞毒性,其IC50s分别是100 μM,100 μM和50.51 μM。 | |||
T75453 | 11-epi-Chaetomugilin I | ||
11-epi-Chaetomugilin I 是一种在Chaetomium globosum 中发现的代谢物。11-epi-Chaetomugilin I 对小鼠 P388 白血病细胞系、人类 HL-60 白血病细胞系、小鼠 L1210 白血病细胞系和人类 KB 表皮样癌细胞系具有显著的细胞毒性活性。 | |||
T83578 |
(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol
|
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(19R,23E)-5b,19-Epoxy19-ethoxycucurbita-6,23-diene-3b,25-diol 是一种葫芦烷型三萜。该化合物在 MTT 法检测中对癌细胞系 MCF-7、HepG2、Du145、Colon205 以及 HL-60 均未表现出抑制效果。 | |||
T37451 |
Stachybotrysin B
|
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Stachybotrysin B is a fungal metabolite originally isolated from S. chartarum and has antiviral and anticancer activities.1,2 It has antiviral activity against HIV in SupT1 cells (IC50 = 19.2 μM).1 Stachybotrysin B is cytotoxic to K562, HeLa, and HL-60 cells (IC50s = 21.72, 39.63, and 18.5 μM, respectively).2 |1. Zhao, J., Feng, J., Tan, Z., et al. Stachybotrysins A-G, phenylspirodrimane derivatives from the fungus Stachybotrys chartarum. J. Nat. Prod. 80(6), 1819-1826 (2017).|2. Ma, X.-h., Zhen... | |||
TN4664 |
Norarmepavine
|
Others | Others |
N-norarmepavine shows significant cytotoxic activities against HL-60 carcinoma cell line with inhibitory ratios of 51.43% at concentration of 1 x 10(-5) M. Norarmepavine shows inhibition against Trypanosoma cruzi. D-(+)- N-norarmepavine exhibits significa | |||
T37442 |
Aspergillin PZ
|
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Aspergillin PZ is a fungal metabolite originally isolated from A. awamori. It induces morphological deformation of P. oryzae conidia when used at a concentration of 89 nM. Aspergillin PZ is active against S. epidermidis (MIC = 20 μM) but not S. aureus, E. coli, or B. cereus (MICs = >20 μM). It is cytotoxic to HL-60 promyelocytic leukemia cells (IC50 = 56.61 μM) but not THP-1 acute monocytic leukemia or PC3 prostate cancer cells (IC50s = >80 μM). | |||
T36417 |
Nargenicin
Antibiotic 47444 |
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Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 μg/ml). [1] It dose-dependently inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE when used at concentrations of 0.00001-0.1 and 0.01-100 μg/mL, respectively. [2] In murine BV-2 microglial cells, nargenicin (... |
Cat. No. | Product Name | Species | Expression System |
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TMPY-02702 |
ASGR1 Protein, Human, Recombinant (His)
ASGPR1,CLEC4H1,ASGPR,HL-1 |
Human | HEK293 Cells |
ASGR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.8 kDa and the accession number is P07306. | |||
TMPY-05542 |
ASGR1 Protein, Human, Recombinant (His), Biotinylated
asialoglycoprotein receptor 1,CLEC4H1,ASGP... |
Human | HEK293 Cells |
ASGR1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.8 kDa and the accession number is P07306. | |||
TMPY-00671 |
ASGR1 Protein, Mouse, Recombinant (His)
ASGPR1,Asgr,HL-1,asialoglycoprote... |
Mouse | HEK293 Cells |
ASGR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is P34927. | |||
TMPY-06943 |
ASGR1 Protein, Human, Recombinant (His & Avi), Biotinylated
CLEC4H1,HL-1,asialoglycoprotein r... |
Human | HEK293 Cells |
ASGR1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 29.58 kDa and the accession number is P07306. | |||
TMPY-05349 |
ASGR1 Protein, Mouse, Recombinant (His), Biotinylated
Asgr-1,asialoglycoprotein receptor 1,H... |
Mouse | HEK293 Cells |
ASGR1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28 kDa and the accession number is P34927. | |||
TMPH-03248 |
ASGR1 Protein, Rat, Recombinant (His & Myc)
Asialoglycoprotein receptor 1,ASGP-R 1,r |
Rat | HEK293 Cells |
Mediates the endocytosis of plasma glycoproteins to which the terminal sialic acid residue on their complex carbohydrate moieties has been removed. The receptor recognizes terminal galactose and N-acetylgalactosamine units. After ligand binding to the receptor, the resulting complex is internalized and transported to a sorting organelle, where receptor and ligand are disassociated. The receptor then returns to the cell membrane surface. ASGR1 Protein, Rat, Recombinant (His & Myc) is expressed in... | |||
TMPK-01201 |
BPIFA1/LUNX Protein, Human, Recombinant
Lung-specific protein X,BPI fold-containing family A member ... |
Human | E. coli |
Bactericidal/permeability-increasing fold containing family A, member 1 (BPIFA1) is a secretory protein found in human upper aerodigestive tract mucosa. This innate material is secreted in mucosal fluid or found in submucosal tissue in the human soft palate, lung, uvula, and nasal cavity. BPIFA1 is a critical component of the innate immune response that prevents upper airway diseases. | |||
TMPY-04451 |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST)
AMPK, AMPK(α1, β1, γ1) |
Human | Baculovirus Insect Cells |
AMPK (G1/B1/A1) Heterotrimer Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 160 kDa and the accession number is P54619-1&Q9Y478-1&Q13131-1. | |||
TMPY-03878 |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His)
Integrin alpha V β6,ITGAV & ITGB6,integrin, alpha 5 (fibrone... |
Human | HEK293 Cells |
Integrin alpha V beta 6 Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 190.4 kDa and the accession number is P06756-1&P18564-1. | |||
TMPY-02501 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant
CD3d molecule, δ (CD3-TCR complex),CD3-δ,CD3d molecule, delt... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 77.5 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-03745 |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His)
CD3-DELTA,CD3d molecule, delta (CD3-TCR complex),CD3d molecu... |
Human | HEK293 Cells |
CD3D & CD3E Heterodimer Protein, Human, Recombinant (Flag & His) is expressed in HEK293 mammalian cells with Flag and His tag. The predicted molecular weight is 31.05 kDa and the accession number is P04234-1&P07766-1. | |||
TMPY-04069 |
Neurotrophin 3 Protein, Human, Recombinant
NGF2,HDNF,NT-3,neurotrophin 3,NGF-2,NT3 |
Human | E. coli |
NTF3 (Neurotrophin 3) is a Protein Coding gene. The protein encoded by this gene is a member of the neurotrophin family, that controls the survival and differentiation of mammalian neurons. This protein is closely related to both nerve growth factor and brain-derived neurotrophic factor. NTF3 is a key mediator of neuronal development during the early neurogenic period. NTF3 is a novel target gene of POU3F2 and that the POU3F2/NTF3 pathway plays a role in the process of neuronal differentiation. ... | |||
TMPY-00586 |
CLEC-2 Protein, Mouse, Recombinant (hFc)
1810061I13Rik,Clec2,C-ty... |
Mouse | HEK293 Cells |
CLEC-2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 49.1 kDa and the accession number is Q9JL99-1. | |||
TMPY-02115 |
R-Spondin 3/RSPO3 Protein, Human, Recombinant (aa 1-146, His)
CRISTIN1,THSD2,R-spondin 3,PWTSR |
Human | HEK293 Cells |
R-spondin 3 (RSPO3) is a member of the R-Spondin (RSPO) family in vertebrates that activate Wnt/beta-catenin signaling, plays a key role in these processes. The RSPO family of secreted Wnt modulators is involved in development and disease and holds therapeutic promise as stem cell growth factors. The four members have high structural homology. RSPO2 and RSPO3 are more potent than RSPO1, whereas RSPO4 is relatively inactive. All RSPO members require Wnt ligands and LRP6 for activity and amplify s... | |||
TMPY-00986 |
IL-34 Protein, Mouse, Recombinant (His)
interleukin 34,2010004A03Rik,AI593503 |
Mouse | HEK293 Cells |
IL-34 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26 kDa and the accession number is Q8R1R4-1. | |||
TMPY-00991 |
LIFR Protein, Human, Recombinant (His)
STWS,CD118,SJS2,LIF-R,leukemia inhibitory ... |
Human | HEK293 Cells |
LIFR Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 91 kDa and the accession number is P42702-1. | |||
TMPY-02412 |
ENO1 Protein, Human, Recombinant (His)
PPH,NNE,enolase 1, (alpha),ENO1L1... |
Human | E. coli |
ENO1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 49.3 kDa and the accession number is P06733-1. | |||
TMPY-03956 |
Fas Ligand Protein, Human, Recombinant (His)
TNLG1A,FASL,FASLG,CD178,CD95-L,APT1 |
Human | P. pastoris (Yeast) |
Fas Ligand, also known as FASLG and CD95L, is the ligand for FAS. It is a transmembrane protein which binds to TNFRSF6/FAS. Interaction of FAS with fas Ligand is critical in triggering apoptosis of some types of cells such as lymphocytes. Fas Ligand may be involved in cytotoxic T-cell mediated apoptosis and in T-cell development. TNFRSF6/FAS-mediated apoptosis may have a role in the induction of peripheral tolerance, in the antigen-stimulated suicide of mature T-cells, or both. Fas Ligand Protei... | |||
TMPY-04413 |
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST)
hIRE1p,endoplasmic reticulum to nucleus signaling <... |
Human | Baculovirus Insect Cells |
IRE1 Protein, Human, Recombinant (aa 465-977, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 86 kDa and the accession number is O75460-1. | |||
TMPY-03363 |
C-Reactive Protein Protein, Human, Recombinant
C-Reactive Protein,C-reactive protein, pentraxin-related,PTX... |
Human | HEK293 Cells |
C-Reactive Protein Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 23 kDa and the accession number is P02741-1. | |||
TMPY-01349 |
ICAM-1/CD54 Protein, Mouse, Recombinant (His)
MALA-2,Ly-47,CD54,intercellular adhesion molecule 1... |
Mouse | HEK293 Cells |
ICAM-1/CD54 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.7 kDa and the accession number is P13597-1. | |||
TMPY-04212 |
IL-16 Protein, Mouse, Recombinant (His)
白介素,interleukin 16,mKIAA4048,白细胞介素 |
Mouse | E. coli |
IL-16 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 14.5 kDa and the accession number is O54824-1. | |||
TMPY-00915 |
Serpin A1 Protein, Human, Recombinant (His)
PRO2275,SerpinA1,serpin peptidase inhibitor, clade ... |
Human | HEK293 Cells |
Serpin A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is P01009-1. | |||
TMPY-05354 |
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD28 molecule,Tp44 |
Human | HEK293 Cells |
CD28 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 43.7 kDa and the accession number is P10747-1. | |||
TMPY-01139 |
PDGFRA Protein, Human, Recombinant (His)
PDGFR-2,CD140A,RHEPDGFRA,platelet-derived growth fa... |
Human | HEK293 Cells |
PDGFRA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 57.7 kDa and the accession number is P16234-1. | |||
TMPY-04956 |
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated
MDA-BF-1,c-erbB-3,HER3,p85-sErbB3,LCCS2,p1... |
Human | HEK293 Cells |
HER3/ERBB3 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 70.2 kDa and the accession number is P21860-1. | |||
TMPY-02617 |
Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His)
NP Protein |
H2N2 | Baculovirus Insect Cells |
Influenza A H2N2 (A/Ann Arbor/6/1960) Nucleoprotein/NP Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 57 kDa and the accession number is P21433-1. | |||
TMPY-05435 |
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc)
angiopoietin 1,AGPT,AGP1,ANG1 |
Human | HEK293 Cells |
ANGPT1/Angiopoietin-1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 82 kDa and the accession number is Q15389-1. | |||
TMPY-01853 |
SIRP gamma Protein, Human, Recombinant (His)
bA77C3.1,signal-regulatory protein gamma,SIRP γ/SIR... |
Human | HEK293 Cells |
SIRP gamma Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9P1W8-1. | |||
TMPY-06051 |
SIRP alpha Protein, Human, Recombinant (hFc)
signal-regulatory protein alpha,SIRP alpha,PTPNS1,P... |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64 kDa and the accession number is P78324-1. | |||
TMPY-01701 |
IL-12RB1 Protein, Human, Recombinant (His)
interleukin 12 receptor, β1,IL12R... |
Human | HEK293 Cells |
IL-12RB1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 58.5 kDa and the accession number is P42701-1. | |||
TMPY-04782 |
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His)
LIR6,leukocyte immunoglobulin like receptor A1,LIR-... |
Human | HEK293 Cells |
LILRA1/LIR-6/CD85i Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 50 kDa and the accession number is O75019-1. | |||
TMPY-01907 |
VSIG4 Protein, Human, Recombinant (His)
Z39IG,CRIg,V-set and immunoglobulin domain containing 4 |
Human | HEK293 Cells |
VSIG4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.5 kDa and the accession number is Q9Y279-1. | |||
TMPY-01462 |
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His)
interleukin 11 receptor subunit alpha,hCG_... |
Human | HEK293 Cells |
IL-11R alpha/IL-11RA Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.6 kDa and the accession number is Q14626-1. | |||
TMPY-00828 |
Iduronate 2 sulfatase/IDS Protein, Human, Recombinant (His)
MPS2,IDS,SIDS,iduronate 2-sulfatase |
Human | HEK293 Cells |
Iduronate 2-Sulfatase, also known as IDS, is a member of the highly conserved sulfatase family of enzymes that catalyze the hydrolysis of O- and N-sulfate esters from a variety of substrates. The human Iduronate 2-Sulfatase/IDS consists of a signal peptide, a propeptide, and a mature chain that may be further processed into two chains. Among the identified 18 human sulfatases, Iduronate 2-Sulfatase/IDS is required for the lysosomal degradation of the glycosaminoglycans (GAG), heparan sulfate, an... | |||
TMPY-01834 |
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His)
CD16,Fc receptor, IgG, low affinity III |
Mouse | HEK293 Cells |
CD16/FCGR3 Protein, Mouse, Recombinant (aa 32-215, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.6 kDa and the accession number is P08508-1. | |||
TMPY-01410 |
IL-3R alpha/CD123 Protein, Human, Recombinant (His)
CD123,interleukin 3 receptor, alpha (low affinity),... |
Human | HEK293 Cells |
IL-3R alpha/CD123 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.5 kDa and the accession number is P26951-1. | |||
TMPY-03273 |
IL-18 Protein, Mouse, Recombinant
interleukin 18,白细胞介素,白介素,Il-18,Igif |
Mouse | E. coli |
IL-18 Protein, Mouse, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18.2 kDa and the accession number is P70380-1. | |||
TMPY-01431 |
L1CAM Protein, Human, Recombinant (His)
N-CAM-L1,MASA,HSAS,L1 cell adhesion molecu... |
Human | HEK293 Cells |
L1CAM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 125 kDa and the accession number is P32004-1. | |||
TMPY-05579 |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated
PRR1,ED4,PVRR,nectin-1,OFC7,SK-12... |
Human | HEK293 Cells |
PVRL1/NECTIN1 Protein, Human, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 61 kDa and the accession number is Q15223-1. | |||
TMPY-05030 |
PCDH7 Protein, Human, Recombinant (His)
BHPCDH |
Human | Baculovirus Insect Cells |
PCDH7, a member of protocadherins family, functions as tumor suppressor in several human cancers. The human PCDH7 gene is localized in chromosome 4p15, which is often inactivated in human cancers, including bladder cancer. The low PCDH7 expression is a potential prognostic biomarker for primary non-muscle invasive bladder cancer (NMIBC). PCDH7 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 94 kDa and the accession number... | |||
TMPY-04810 |
CD47 Protein, Mouse, Recombinant (His)
AA407862,CD47 molecule,AW108519,91 |
Mouse | HEK293 Cells |
CD47 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.3 kDa and the accession number is Q61735-1. | |||
TMPY-06076 |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc)
LIR7,LIR-7,ILT1,CD85H,leukocyte immunoglobulin-like... |
Human | HEK293 Cells |
LILRA2/CD85h/ILT1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.7 kDa and the accession number is Q8N149-1. | |||
TMPY-01298 |
CADM1 Protein, Human, Recombinant (His)
Necl-2,cell adhesion molecule 1,SYNCAM,BL2,sTSLC- |
Human | HEK293 Cells |
CADM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.5 kDa and the accession number is Q9BY67-1. | |||
TMPY-02154 |
FAP Protein, Human, Recombinant (His)
fibroblast activation protein, alpha,Fibroblast Activation P... |
Human | HEK293 Cells |
FAP Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87.2 kDa and the accession number is Q12884-1. | |||
TMPY-01912 |
Cadherin 17/CDH17 Protein, Human, Recombinant (His)
HPT-1,cadherin 17, LI cadherin (liver-inte... |
Human | HEK293 Cells |
Cadherin 17/CDH17 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 87 kDa and the accession number is Q12864-1. | |||
TMPY-01608 |
Decorin Protein, Human, Recombinant (His)
PGS2,PG40,CSCD,decorin,SLRR1B,DSPG2,PGII |
Human | HEK293 Cells |
Decorin Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.4 kDa and the accession number is P07585-1. | |||
TMPY-01573 |
SIRP alpha Protein, Human, Recombinant (G75A, His)
PTPNS1,signal-regulatory protein alpha,SIRP,MYD- |
Human | HEK293 Cells |
SIRP alpha Protein, Human, Recombinant (G75A, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P78324-1. | |||
TMPY-04779 |
BTN3A2 Protein, Human, Recombinant (His)
BTF3,BT3.2,BTF4,BTN3.2,CD277,butyrophilin subfamily 3 member... |
Human | HEK293 Cells |
The three butyrophilin BTN3A molecules, BTN3A1, BTN3A2, and BTN3A3, are members of the B7/butyrophilin-like group of Ig superfamily receptors, which modulate the function of T cells. BTN3A2 is overexpressed in gastric tumors, and deletion of BTN3A2 inhibited proliferation, migration, and invasion of gastric cancer cells. The butyrophilin 3 (BTN3) receptors are implicated in the T lymphocytes regulation and present a wide plasticity in mammals. A thorough phylogenetic analysis reveals a concerted... | |||
TMPY-01459 |
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His)
p60,TNFR60,TNFAR,TBP1,CD120a,TNFR1 |
Human | HEK293 Cells |
TNFR1/CD120a/TNFRSF1A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 22.7 kDa and the accession number is P19438-1. | |||
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