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Search Results for " git "
Targets Recommended: IL Receptor TNF Interleukin

25

抑制剂 & 化合物

21

天然产物

39

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T1813 VGX-1027

VGX1027,VGX 1027,GIT 27

IL Receptor; TNF; Interleukin Apoptosis; Immunology/Inflammation
VGX-1027 (GIT 27) 是一种口服有效的异恶唑化合物,靶向巨噬细胞,减少促炎性介质 TNF-α、IL-1β和 IL-10 的产生,具有免疫调节特性。它通过限制细胞因子介导的免疫炎症而具有抗糖尿病作用。
T18934 Calmagite

Others Others
Calmagite 是络合指示剂,可用于多种样品中的钙和镁的检测。
T2494 Cilengitide

西仑吉肽,EMD 121974

Integrin; Autophagy Autophagy; Cytoskeletal Signaling
Cilengitide (EMD 121974) 是一种有效的 αvβ3/5 受体整合素抑制剂,可抑制 ανβ3和 ανβ5与玻连蛋白结合,IC50值分别为 4 和 79 nM。
T35391 Vibostolimab (anti-TIGIT)

Vibostolimab (anti-TIGIT)

Others Others
Vibostolimab 是一种抗 T 细胞免疫蛋白和 ITIM 域的单克隆抗体。Vibostolimab 在体外实验中显示出抗肿瘤活性,可用于研究非小细胞肺癌 (NSCLC) 和黑色素瘤。
T39849 Propargite

Parasite Microbiology/Virology
Propropgite 通过诱导 DNA 损伤来诱导 β 细胞坏死。它诱导 MIN6 细胞死亡的 IC50为 1 μM.。它可用于杀死螨虫。
T126402 3-O-Methyltagitinin F

3-O-Methyltagitinin F 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126402。
T40076 Gersizangitide

Gersizangitide is an angiogenesis inhibitor.
T37707 14-Anhydrodigitoxigenin

14-Anhydrodigitoxigenin is a cardenolide and a derivative of digitoxin.1 It reduces the activity of guinea pig heart Na+/K+-ATPase by 15% when used at a concentration of 10 μM.2
T31930 Gitoformate

AC 2770,Formiloxin,Pentaformylgitoxin

Gitoformate is used to treat kidney and heart insufficiency,
T76970 Tagitanlimab

Tagitanlimab (HBM-9167),一种人源化抗PD-L1抗体(IgG1κ型),通过选择性阻断PD-L1与PD-1的相互作用,展现出对研究复发性或转移性鼻咽癌(NPC)的潜力。
T77084 Mezagitamab

Mezagitamab (TAK-079) 是一种 IgG1λ 类型的抗CD38单克隆抗体。其通过促进抗体和补体依赖性的细胞毒性,来耗尽表达CD38的肿瘤细胞,显示出在复发/难治性多发性骨髓瘤 (RRMM) 及原发性血小板减少性紫癜 (ITP) 等疾病中的治疗潜力。
T40076L Gersizangitide acetate

Gersizangitide acetate(2417491-82-6 Free base)

Others Others
Gersizangitide acetate 是一种血管生成抑制剂。
TP2089 Agitoxin-2

Agitoxin 2

Potent Shaker K+ channel blocker (Ki = 0.64 nM). Also inhibits Kv1.3, Kv1.6 and Kv1.1 K+ channels (Ki values are 4, 37 and 44 pM respectively).
T131628 Digitoxigenin (Thevetigenin; Echujetin; Cerberigenin)

Digitoxigenin (Thevetigenin; Echujetin; Cerberigenin) 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131628。
T6806 Cilengitide TFA

Integrin; Autophagy Autophagy; Cytoskeletal Signaling
Cilengitide TFA 是一种选择性的 αvβ3和 αvβ5受体整合素抑制剂,IC50分别为 4 nM 和 79 nM。对 GP IIb/IIIa 的选择性约为 10 倍。
T70083 Cilengitide hydrochloride

Cilengitide hydrochloride sis the salt form of Cilengitide, a cyclic Arg-Gly-Asp peptide with potential antineoplastic activity. Cilengitide binds to and inhibits the activities of the alpha(v)beta(3) and alpha(v)beta(5) integrins, thereby inhibiting endothelial cell-cell interactions, endothelial cell-matrix interactions, and angiogenesis.
T76746 Figitumumab

Figitumumab (CP-751871) 为一种高效对抗胰岛素样生长因子 1 受体 (IGF1R) 的全人单克隆抗体。通过阻断 IGF1 与 IGF1R 的结合,其 IC50 值达到 1.8 nM。
T36060 Digoxigenin Monodigitoxoside

Digoxigenin monodigitoxoside是地高辛的一种Na+/K+ ATPase 抑制剂和强心苷代谢物。
T124809 Digitolutein

Digitolutein 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T124809。
T124580 Tagitinin C

Tagitinin C 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124580,CAS号为 59979-56-5。
T75883 Agitoxin-2 TFA

Agitoxin-2 TFA 是K+通道的阻断剂,其对 mKV1.3 和 mKV1.1 的IC50值分别为 201 pM 和 144 pM。
T131442 Gitoxigenin

Gitoxigenin 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T131442。
T80605 Dusigitumab

MEDI 573

IGF-1R Tyrosine Kinase/Adaptors
Dusigitumab (MEDI 573)为一种人源化IgG2λ单克隆抗体,具有特异性针对IGF2和IGF1。
T19877 Digitoxigenin

Thevetigenin,Echujetin,Cerberigenin,Digitoxigenine

Digitoxigenin is a precursor of cardiac glycosides that acts by targeting the metastatic uveal melanoma gene signature.
T28921 Tanogitran

BIBT 986,BIBT986,BIBT-986

Tanogitran, a coagulation factor Xa inhibitor, is used potentially for the treatment of septic shock.

化合物

VGX-1027
Cat.No: T1813
Synonym: VGX1027,VGX 1027,GIT 27
Target: IL Receptor, TNF, Interleukin
Calmagite
Cat.No: T18934
Synonym:
Target: Others
Cilengitide
Cat.No: T2494
Synonym: 西仑吉肽,EMD 121974
Target: Integrin, Autophagy
Vibostolimab (anti-TIGIT)
Cat.No: T35391
Synonym: Vibostolimab (anti-TIGIT)
Target: Others
Propargite
Cat.No: T39849
Synonym:
Target: Parasite
3-O-Methyltagitinin F
Cat.No: T126402
Synonym:
Target:
Gersizangitide
Cat.No: T40076
Synonym:
Target:
14-Anhydrodigitoxigenin
Cat.No: T37707
Synonym:
Target:
Gitoformate
Cat.No: T31930
Synonym: AC 2770,Formiloxin,Pentaformylgitoxin
Target:
Tagitanlimab
Cat.No: T76970
Synonym:
Target:
Mezagitamab
Cat.No: T77084
Synonym:
Target:
Gersizangitide acetate
Cat.No: T40076L
Synonym: Gersizangitide acetate(2417491-82-6 Free base)
Target: Others
Agitoxin-2
Cat.No: TP2089
Synonym: Agitoxin 2
Target:
Digitoxigenin (Thevetigenin; Echujetin; Cerberigenin)
Cat.No: T131628
Synonym:
Target:
Cilengitide TFA
Cat.No: T6806
Synonym:
Target: Integrin, Autophagy
Cilengitide hydrochloride
Cat.No: T70083
Synonym:
Target:
Figitumumab
Cat.No: T76746
Synonym:
Target:
Digoxigenin Monodigitoxoside
Cat.No: T36060
Synonym:
Target:
Digitolutein
Cat.No: T124809
Synonym:
Target:
Tagitinin C
Cat.No: T124580
Synonym:
Target:
Agitoxin-2 TFA
Cat.No: T75883
Synonym:
Target:
Gitoxigenin
Cat.No: T131442
Synonym:
Target:
Dusigitumab
Cat.No: T80605
Synonym: MEDI 573
Target: IGF-1R
Digitoxigenin
Cat.No: T19877
Synonym: Thevetigenin,Echujetin,Cerberigenin,Digitoxigenine
Target:
Tanogitran
Cat.No: T28921
Synonym: BIBT 986,BIBT986,BIBT-986
Target:
Cat. No. Product Name Target Signaling Pathways
T8294 Quercetagitrin

万寿菊苷,槲皮万寿菊素-7-O-Β-吡喃葡萄糖苷,Quercetagetin-7-O-glucoside

Others Others
Quercetagitrin (Quercetagetin-7-O-glucoside) 是分离自非洲万寿菊花 (Tagetes erecta) 中,具有抗炎作用。
T3S0860 Gitogenin

UGT Metabolism
Gitogenin 是一种从Tribulus longipetalus 整株中分离出来的天然类固醇,是一种 UDP-葡萄糖醛酸转移酶 1A4 (UGT1A4) 和 α-葡萄糖苷酶的选择性抑制剂,其IC50分别为 0.69 µM (使用三氟拉嗪为底物) 和 37.2 μM,对人类主要细胞色素 P450 亚型的活性无抑制作用。
T2721 Digitonin

Others Others
Digitonin 属于糖苷类天然产物,是一种去垢剂。Digitonin 具有抗肿瘤活性,可以与胆固醇分子结合从而增加细胞膜的通透性,对多种细胞的细胞膜具有裂解活性。
T0295 Digitoxin

Digitoxoside,洋地黄毒苷,Unidigin,洋地黄毒甙,Digitoxinum,洋地黄

ATPase; Others Membrane transporter/Ion channel; Others
Digitoxin (Digitoxinum) 是Na+/K+-ATPase 有效抑制剂, EC50 值为0.78 μM。
TN5092 Tagitinin F

Antifection Microbiology/Virology
Tagitinin F possesses antileukemic activity; it also shows in vitro leishmanicidal activities against Leishmania braziliensis promastigotes and amastigotes.
T29599 Acetyldigitoxin

Acylanide

Acetyldigitoxin is a derivative of lanatoside A or of DIGITOXIN and can be used for fast digitalization in congestive heart failure.
TN5309 Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside

Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5309,CAS号为 1186628-87-4。
TN5091 Tagitinin A

PPAR; Antifection DNA Damage/DNA Repair; Metabolism; Microbiology/Virology
Tagitinin A is a plant insecticidal compound, it has phytotoxic activity, it shows significant inhibition of wheat coleoptile growth, seed germination, and the growth of STS and weeds. Tagitinin A is also a PPARα/γ dual agonist , it exerts anti-diabetic e
TN3792 Dehydroadynerigenin glucosyldigitaloside

Others Others
Dehydroadynerigenin glucosyldigitaloside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3792,CAS号为 144223-70-1。
T75634 Demycarosyl-3D-β-D-digitoxosylmithramycin SK

Demycarosyl-3D-β-D-digitoxosylmithramycin SK 为Mithramycin类似物,展现出显著的抗肿瘤活性。该化合物通过与DNA结合蛋白结合并抑制其功能,有效阻断肿瘤细胞的增殖与生长。
TN4134 Gitoxin

洋地黄

Others Others
Gitoxin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4134,CAS号为 4562-36-1。
TQ0163 Sagittatoside A

Icariin-A,箭藿苷 A

Estrogen/progestogen Receptor Endocrinology/Hormones
Sagittatoside A selectively activates estrogen response element (ERE)-luciferase activity via ERα.
TQ0168 Sagittatoside B

Others Others
Sagittatoside B is a natural product from Epimedium brevicornu Maxim.
TN3791 Dehydroadynerigenin digitaloside

Others Others
Dehydroadynerigenin digitaloside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3791,CAS号为 52628-62-3。
TN2168 Sagittatoside C

箭藿苷 C,箭藿苷C

Others Others
Sagittatoside C is a natural product
TN5291 8-Hydroxydigitoxigenin

8-Hydroxydigitoxigenin是一种天然产物,属于夹竹桃科夹竹桃属,其产品编号为 TN5291,CAS号为 1049674-06-7。8-Hydroxydigitoxigenin可用作对照参考。
TN5214 Uzarigenin digitaloside

Others Others
Uzarigenin digitaloside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5214,CAS号为 61217-80-9。
TN2525 1-Acetyltagitinin A

Others Others
1-Acetyltagitinin A是一种天然产物,属于菊科肿柄菊属,其产品编号为 TN2525,CAS号为 60547-63-9。1-Acetyltagitinin A可用作对照参考。
T83361 3-epi-Digitoxigenin

3-epi-Digitoxigenin为三萜类化合物,源自鸡蛋花叶及茎部的提取物。
TN4259 Iso-sagittatoside A

Others Others
Iso-sagittatoside A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN4259,CAS号为 503456-08-4。
TN5306 Qingyangshengenin 3-O-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside

Qingyangshengenin 3-O-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5306,CAS号为 1186628-88-5。

天然产物

Quercetagitrin
Cat.No: T8294
Synonym: 万寿菊苷,槲皮万寿菊素-7-O-Β-吡喃葡萄糖苷,Quercetagetin-7-O-glucoside
Target: Others
Gitogenin
Cat.No: T3S0860
Synonym:
Target: UGT
Digitonin
Cat.No: T2721
Synonym:
Target: Others
Digitoxin
Cat.No: T0295
Synonym: Digitoxoside,洋地黄毒苷,Unidigin,洋地黄毒甙,Digitoxinum,洋地黄
Target: ATPase, Others
Tagitinin F
Cat.No: TN5092
Synonym:
Target: Antifection
Acetyldigitoxin
Cat.No: T29599
Synonym: Acylanide
Target:
Qingyangshengenin 3-O-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside
Cat.No: TN5309
Synonym:
Target:
Tagitinin A
Cat.No: TN5091
Synonym:
Target: PPAR, Antifection
Dehydroadynerigenin glucosyldigitaloside
Cat.No: TN3792
Synonym:
Target: Others
Demycarosyl-3D-β-D-digitoxosylmithramycin SK
Cat.No: T75634
Synonym:
Target:
Gitoxin
Cat.No: TN4134
Synonym: 洋地黄
Target: Others
Sagittatoside A
Cat.No: TQ0163
Synonym: Icariin-A,箭藿苷 A
Target: Estrogen/progestogen Receptor
Sagittatoside B
Cat.No: TQ0168
Synonym:
Target: Others
Dehydroadynerigenin digitaloside
Cat.No: TN3791
Synonym:
Target: Others
Sagittatoside C
Cat.No: TN2168
Synonym: 箭藿苷 C,箭藿苷C
Target: Others
8-Hydroxydigitoxigenin
Cat.No: TN5291
Synonym:
Target:
Uzarigenin digitaloside
Cat.No: TN5214
Synonym:
Target: Others
1-Acetyltagitinin A
Cat.No: TN2525
Synonym:
Target: Others
3-epi-Digitoxigenin
Cat.No: T83361
Synonym:
Target:
Iso-sagittatoside A
Cat.No: TN4259
Synonym:
Target: Others
Qingyangshengenin 3-O-β-D-oleandropyranosyl-(1→4)-β-D-cymaropyranosyl-(1→4)-β-D-digitoxopyranoside
Cat.No: TN5306
Synonym:
Target:
Cat. No. Product Name Species Expression System
TMPY-01012 P4HB Protein, Human, Recombinant (His)

DSI,prolyl 4-hydroxylase, β polypeptide,PDIA1,PDI,GIT

Human HEK293
Protein disulfide-isomerase, also known as Cellular thyroid hormone-binding protein, Prolyl 4-hydroxylase subunit beta, p55 and P4HB, is a peripheral membrane protein that belongs to the protein disulfide isomerase family. P4HB is highly abundant. In some cell types, it seems to be also secreted or associated with the plasma membrane, where it undergoes constant shedding and replacement from intracellular sources. P4HB localizes near CD4-enriched regions on lymphoid cell surfaces. It is identifi...
TMPY-04970 TIGIT Protein, Human, Recombinant (hFc)

WUCAM,VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM dom...

Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-05345 TIGIT Protein, Cynomolgus, Recombinant (hFc)

T cell immunoreceptor with Ig and ITIM domains

Cynomolgus HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-02669 TIGIT Protein, Mouse, Recombinant (His)

T cell immunoreceptor with Ig and ITIM domains,Vstm3,ENSMUSG...

Mouse HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-00072 GITR/TNFRSF18 Protein, Human, Recombinant (His)

AITR,GITR-D,tumor necrosis factor receptor superfam...

Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPY-05292 GITRL Protein, Human, Recombinant (His)

TL6,tumor necrosis factor (ligand) superfamily, member 18,h<...

Human Baculovirus-Insect Cells
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Targ...
TMPK-01260 GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His)

TNFRSF18,GITR-D,AITR,CD357,GITR

Cynomolgus HEK293
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
TMPJ-00629 TIGIT Protein, Cynomolgus, Recombinant (His)

VSTM3,V-set and transmembrane domain-containing protein 3,T-...

Cynomolgus Human Cells
T cell immunoreceptor with Ig and ITIM domains (TIGIT), also called VSIG9 and Vstm3, is a member of the CD28 family within the Ig superfamily of proteins. TIGIT contains an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM), and is expressed on regulatory, memory, activated T cells and NK cells. TIGIT binds to CD155(PVR) that appear on dendritic cells (DC), macrophages and endothelium with high affinity, and CD112(PVRL2) with lower...
TMPH-02413 Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO)

LCMV E. coli
class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.; Stable signal peptide (SSP): cleaved and functions as a signal peptide. In addition, it is also retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation clea...
TMPY-05233 GITR/TNFRSF18 Protein, Human, Recombinant (His), Biotinylated

GITR-D,CD357,AITR,GITR,tumor necrosis fact...

Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPY-05163 GITRL Protein, Human, Recombinant (mFc)

TL6,GITRL,tumor necrosis factor (ligand) superfamil...

Human HEK293
The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.Cancer ImmunotherapyCo-stimulatory Immune Checkpoint TargetsImmune CheckpointImmune Checkpoint Targ...
TMPY-05602 GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated

AITR,GITR,tumor necrosis factor receptor superfamil...

Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPY-05122 TIGIT Protein, Human, Recombinant (His), Biotinylated

VSTM3,VSIG9,T cell immunoreceptor with Ig and ITIM domains,W...

Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPK-00132 GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated

GITR-D,CD357,AITR,GITR,TNFRSF18

Human HEK293
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
TMPY-06134 TIGIT Protein, Human, Recombinant (mFc)

VSTM3,VSIG9,WUCAM,T cell immunoreceptor with Ig and ITIM dom...

Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-06135 TIGIT Protein, Human, Recombinant (hFc & Avi), Biotinylated

WUCAM,T cell immunoreceptor with Ig and ITIM domains,VSIG9,V...

Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-05788 TIGIT Protein, Mouse, Recombinant (mFc)

ENSMUSG00000071552,T cell immunoreceptor with Ig and ITIM do...

Mouse HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-05121 TIGIT Protein, Human, Recombinant (hFc), Biotinylated

T cell immunoreceptor with Ig and ITIM domains,VSIG9,WUCAM,V...

Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-05155 GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (His)

tumor necrosis factor receptor superfamily, member 18

Cynomolgus HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPY-05253 GITR/TNFRSF18 Protein, Mouse, Recombinant (mFc)

AITR,tumor necrosis factor receptor superfamily, member 18,<...

Mouse HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPY-03018 TIGIT Protein, Mouse, Recombinant (hFc)

T cell immunoreceptor with Ig and ITIM domains,Vstm3,ENSMUSG...

Mouse HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-06213 TIGIT Protein, Human, Recombinant (aa 1-141, His)

T cell immunoreceptor with Ig and ITIM domains,VSIG9,VSTM3,W...

Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-06462 TIGIT Protein, Human, Recombinant (aa 22-141, His)

T cell immunoreceptor with Ig and ITIM domains,VSIG9,WUCAM,V...

Human CHO
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-05744 TIGIT Protein, Rat, Recombinant (hFc)

RGD1563191,T cell immunoreceptor with Ig and ITIM domains

Rat HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-06300 TIGIT Protein, Human, Recombinant (His & Avi), Biotinylated

WUCAM,T cell immunoreceptor with Ig and ITIM domains,VSIG9,V...

Human HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPY-03232 GITR/TNFRSF18 Protein, Rat, Recombinant (hFc)

tumor necrosis factor receptor superfamily, member 18

Rat HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPH-02412 Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc)

LCMV E. coli
class I viral fusion protein that directs fusion of viral and host endosomal membranes, leading to delivery of the nucleocapsid into the cytoplasm. Membrane fusion is mediated by irreversible conformational changes induced upon acidification in the endosome.; Stable signal peptide (SSP): cleaved and functions as a signal peptide. In addition, it is also retained as the third component of the GP complex. The SSP is required for efficient glycoprotein expression, post-translational maturation clea...
TMPJ-00432 GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)

GITRL,TNFSF18,Activation-inducible TNF-related liga...

Cynomolgus Human Cells
TNFSF18 is a single-pass type II membrane protein. It is expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. TNFSF18 cytokine binds to TNFRSF18/AITR/GITR. It regulates T-cell responses, and functions as costimulator and lower the threshold for T-cell activation and T-cell proliferation. It is Important for interactions between activated T-lymphocytes and endothelial cells and Promotes leukocyte adhesion to endothelial cells. TNFSF18 mediates activation ...
TMPK-00133 GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His)

GITR-D,AITR,GITR,CD357,TNFRSF18

Human HEK293
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
TMPK-00053 GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)

AITRL,TNFSF18,TL6,GITR Ligand,GITRL

Human HEK293
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.
TMPK-01064 GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)

GITRL,GITR Ligand,TL6,TNFSF18,AITRL

Mouse HEK293
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.
TMPK-01086 GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)

TNFRSF18,AITR,GITR-D,CD357,GITR

Mouse HEK293
GITR (glucocorticoid-induced tumor necrosis factor receptor), also known as AITR and TNFRSF18, is a 40 kDa transmembrane glycoprotein that functions in immune regulation.GIRT is a receptor for TNFSF18. Seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. Mediated NF-kappa-B activation via the TRAF2/NIK pathway.
TMPY-06978 TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated

ENSMUSG00000071552,Vstm3,T cell immunoreceptor with Ig and I...

Mouse HEK293
TIGIT, also known as V-set and transmembrane domain-containing protein 3 (VSTM3) or V-set and immunoglobulin domain-containing protein 9 (VSIG9) is a new surface protein containing an immunoglobulin variable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif (ITIM). TIGIT is expressed on regulatory, memory, activated T cells and NK cells. It binds PVR with high affinity, and PVRL2 with lower affinity, but not PVRL3. Knockdown of TIGIT with siRNA in human memory ...
TMPJ-00110 GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)

Tnfrsf18,GITR-D,CD357,AITR,Tumor necrosis factor re...

Mouse Human Cells
Tumor necrosis factor receptor superfamily member 18(Gitr) contains 3 TNFR-Cys repeats and it have four isforms.IsformA、isformB and isformC is single-pass type I membrane protein and isformD is a secreted protein. The protein is the receptor for TNFSF18.It seems to be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. It mediated NF-kappa-B activation via the TRAF2/NIK pathway.It binds to TRAF1, TRAF2, and...
TMPY-04265 GITR/TNFRSF18 Protein, Human, Recombinant (hFc)

GITR-D,tumor necrosis factor receptor superfamily, ...

Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPK-00054 GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated

TL6,GITR Ligand,TNFSF18,AITRL,GITRL

Human HEK293
Glucocorticoid-induced TNFR-related protein (TNFRSF18, GITR, CD357), expressed by T cells, and its ligand (TNFSF18, GITRL), expressed by myeloid populations, provide co-stimulatory signals that boost T cell activity. Due to the important role that GITR plays in regulating immune functions, agonistic stimulation of GITR is a promising therapeutic concept.
TMPY-06411 GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated

CD357,GITR-D,tumor necrosis factor receptor superfa...

Human HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPY-06017 GITR/TNFRSF18 Protein, Mouse, Recombinant (His)

Gitr,AITR,tumor necrosis factor receptor superfamil...

Mouse HEK293
GITR, also known as TNFRSF18(CD357), belongs to the tumor necrosis factor receptor (TNF-R) superfamily. It is the receptor for TNFSF18. GITR plays a key role in dominant immunological self-tolerance maintained by CD25(+)CD4(+) regulatory T cells. GITR may be involved in interactions between activated T-lymphocytes and endothelial cells and in the regulation of T-cell receptor-mediated cell death. GITR and its ligand are important costimulatory molecules in the pathogenesis of autoimmune diseases...
TMPY-04562 GRK2 Protein, Human, Recombinant (His & GST)

β,adrenergic, beta, receptor kinase 1

Human Baculovirus-Insect Cells
G-protein coupled receptor kinase 2 (GRK2), also referred as Adrenergic, beta, receptor kinase 1 (ADRBK1), is a ubiquitous member of the G protein-coupled receptor kinase (GRK) family that appears to play a central, integrative role in signal transduction cascades. GRK2 can phosphorylate a growing number of non-GPCR substrates and associate with a variety of proteins related to signal transduction, thus suggesting that this kinase could also have diverse 'effector' functions. GRK2 has been repor...

重组蛋白

P4HB Protein, Human, Recombinant (His)
Cat.No: TMPY-01012
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04970
Species: Human
Expression System: HEK293
TIGIT Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-05345
Species: Cynomolgus
Expression System: HEK293
TIGIT Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02669
Species: Mouse
Expression System: HEK293
GITR/TNFRSF18 Protein, Human, Recombinant (His)
Cat.No: TMPY-00072
Species: Human
Expression System: HEK293
GITRL Protein, Human, Recombinant (His)
Cat.No: TMPY-05292
Species: Human
Expression System: Baculovirus-Insect Cells
GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (aa 20-156, His)
Cat.No: TMPK-01260
Species: Cynomolgus
Expression System: HEK293
TIGIT Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00629
Species: Cynomolgus
Expression System: Human Cells
Lymphocytic choriomeningitis virus (LCMV) (strain Armstrong) GPC Protein (His & SUMO)
Cat.No: TMPH-02413
Species: LCMV
Expression System: E. coli
GITR/TNFRSF18 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05233
Species: Human
Expression System: HEK293
GITRL Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05163
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05602
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05122
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His & Avi), Biotinylated
Cat.No: TMPK-00132
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (mFc)
Cat.No: TMPY-06134
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-06135
Species: Human
Expression System: HEK293
TIGIT Protein, Mouse, Recombinant (mFc)
Cat.No: TMPY-05788
Species: Mouse
Expression System: HEK293
TIGIT Protein, Human, Recombinant (hFc), Biotinylated
Cat.No: TMPY-05121
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-05155
Species: Cynomolgus
Expression System: HEK293
GITR/TNFRSF18 Protein, Mouse, Recombinant (mFc)
Cat.No: TMPY-05253
Species: Mouse
Expression System: HEK293
TIGIT Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-03018
Species: Mouse
Expression System: HEK293
TIGIT Protein, Human, Recombinant (aa 1-141, His)
Cat.No: TMPY-06213
Species: Human
Expression System: HEK293
TIGIT Protein, Human, Recombinant (aa 22-141, His)
Cat.No: TMPY-06462
Species: Human
Expression System: CHO
TIGIT Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-05744
Species: Rat
Expression System: HEK293
TIGIT Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06300
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03232
Species: Rat
Expression System: HEK293
Lymphocytic choriomeningitis virus (LCMV) (strain WE) GPC Protein (His & Myc)
Cat.No: TMPH-02412
Species: LCMV
Expression System: E. coli
GITR Ligand/TNFSF18 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00432
Species: Cynomolgus
Expression System: Human Cells
GITR/TNFRSF18 Protein, Human, Recombinant (aa 26-161, His)
Cat.No: TMPK-00133
Species: Human
Expression System: HEK293
GITR Ligand/TNFSF18 Protein, Human, Recombinant (His & Flag)
Cat.No: TMPK-00053
Species: Human
Expression System: HEK293
GITR Ligand/TNFSF18 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-01064
Species: Mouse
Expression System: HEK293
GITR/TNFRSF18 Protein, Mouse, Recombinant (aa 22-153, His)
Cat.No: TMPK-01086
Species: Mouse
Expression System: HEK293
TIGIT Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06978
Species: Mouse
Expression System: HEK293
GITR/TNFRSF18 Protein, Mouse, Recombinant (hFc & His)
Cat.No: TMPJ-00110
Species: Mouse
Expression System: Human Cells
GITR/TNFRSF18 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-04265
Species: Human
Expression System: HEK293
GITR Ligand/TNFSF18 Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
Cat.No: TMPK-00054
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06411
Species: Human
Expression System: HEK293
GITR/TNFRSF18 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06017
Species: Mouse
Expression System: HEK293
GRK2 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04562
Species: Human
Expression System: Baculovirus-Insect Cells
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