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Search Results for " dopa "

68

抑制剂 & 化合物

18

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T26396	6-Hydroxy-DOPA 6-羟基-DL-多巴,6-Hydroxy-DL-DOPA	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	6-Hydroxy-DOPA 是 RAD52 的变构抑制剂，可用于癌症研究。它在体外抑制 BRCA 缺陷癌细胞的增殖，也抑制 APE1。
T31570	DPBX-L-Dopa DPBX L-Dopa
	DPBX-L-Dopa is a boron-containing dopa-derivative, acting as a bladder relaxant through non-catecholamine receptors.
T37605	D-DOPA
	D-DOPA is an enantiomer of the dopamine precursor L-DOPA . It can be converted to L-DOPAviasequential oxidation and transamination, which are mediated by D-amino acid oxidase (DAAO) and DOPA transaminase, respectively, in rat kidney homogenates.1It reduces the number of dopaminergic neurons in primary rat embryonic mesencephalic cultures in a concentration-dependent manner.2Intraventricular administration of D-DOPA (200 μg/animal) increases striatal dopamine levels in rats.3D-DOPA (20 mg/kg, i.p...
T24047	Etilevodopa hydrochloride Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester	Others; Dopamine Receptor; Drug Metabolite	GPCR/G Protein; Metabolism; Neuroscience; Others
	Etilevodopa hydrochloride (L-DOPA ethyl ester) 是 Levodopa 的前药，在胃肠道中被非特异性酯酶快速水解产生 Levodopa 和乙醇。Levodopa 是多巴胺的前体，有助于中枢神经系统的渗透和传递多巴胺。Etilevodopa HCl 可用于帕金森病 (PD)的相关研究。
T23275	RuBi-Dopa	Others	Others
	dopamine receptor activator
T36122	3-O-methyl-L-DOPA (hydrate)
	3-O-methyl-L-DOPA is a metabolite of L-DOPA , produced by the activity of catechol O-methyltransferase. 3-O-methyl-L-DOPA may have effects of its own or it may compete with the actions of L-DOPA.
T31823	Fluorodopa F 18 Fluorodopa (18F),6-(18F)Fluoro-L-DOPA,F-DOPA,L-6-(18F)Fluoro-DOPA,6-(18F)Fluorodopamine
	Fluorodopa F 18 can be used as radioactive agent.
T20700	Racemetirosine	Others	Others
	Racemetirosine 是一种酪氨酸 3-单加氧酶抑制剂，因此会抑制儿茶酚胺的合成。
T34589	SD-1077 d3-L-DOPA,deuldopa,deuterated levodopa,SD1077
	SD-1077, also known as d3-L-DOPA, is a deuterium containing levodopa. SD-1077 has been shown in preclinical models to improve the half-life of dopamine in the brain resulting in a prolonged treatment effect.
T74180	[18F]-Labeled L-dopa precursor
	[18F]-Labeled L-dopa precursor 是用于合成 18F-labeled L-dopa 的前体。
T2148	Carbidopa monohydrate Carbidopa Hydrate,S(-)-Carbidopa,卡比多巴水合物	Decarboxylase; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism; Others
	Carbidopa monohydrate (S(-)-Carbidopa) 是一种外周型脱羧酶抑制剂，可用于帕金森病的研究。它是一种选择性芳香烃受体 (AhR) 调节剂。它抑制胰腺癌细胞和肿瘤生长。
T5954	Methyldopa hydrate L-甲基多巴,Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate	Dopamine Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Methyldopa hydrate (MK-351 hydrate) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是一种 α-肾上腺素能激动剂，对α2-adrenergic receptors 有选择性。
T13512	5-Hydroxydopamine hydrochloride	Antifungal	Microbiology/Virology
	5-Hydroxydopamine hydrochloride 是人体尿液中的一种天然胺,对卢克斯普受体的 IC50 值为 22 µM 。5-Hydroxydopamine hydrochloride 具有潜在的抗菌活性和抗癌活性。
T11077	Dopamine D2 receptor antagonist-1	Others	Others
	Dopamine D2 receptor antagonist-1，一种对多巴胺D2受体（D2R）表现出亚毫摩尔级别亲和力的负变构调节剂（NAM）。
T6835	Fenoldopam mesylate Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Fenoldopam mesylate (Corlopam mesylate) 是一种多巴胺受体D1选择性激动剂。
T12352	Oxidopamine hydrochloride 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride,6-羟基多巴胺盐酸盐	Mitophagy; Dopamine Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) 是一种神经递质多巴胺拮抗剂，可选择性地破坏多巴胺能神经元，是一种广泛使用的神经毒素。
T60075	Dopamine D2 receptor agonist-2 Dopamine D2 Receptor	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Dopamine D2 receptor agonist-2 (Dopamine D2 Receptor) 是靶向多巴胺D2受体的配体。
T2547	Droxidopa 屈昔多巴,屈西多巴,SM5688,DOPS,L-DOPS	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Droxidopa (L-DOPS) 是 Droxidopa (w/w80%) 和 Pharmaceutical starch (w/w20%) 的混合物，能透过血脑屏障，可作为神经递质去甲肾上腺素和肾上腺素的原药。
T12352L	Oxidopamine hydrobromide 6-Hydroxydopamine hydrobromide,6-羟基多巴胺氢溴酸盐,6-OHDA hydrobromide	Mitophagy; Dopamine Receptor; Autophagy	Autophagy; GPCR/G Protein; Neuroscience
	Oxidopamine hydrobromide (6-OHDA hydrobromide) 是一种神经递质多巴胺拮抗剂，可选择性地破坏多巴胺能神经元，是一种广泛使用的神经毒素。
T15701	Methyldopa hydrochloride L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride	Others	Others
	L-(-)-α-Methyldopa hydrochloride is an alpha-adrenergic agonist psychoactive drug. It is used as a sympatholytic or antihypertensive. Methyldopa has a dual mechanism of action. It is a competitive inhibitor of the enzyme DOPA decarboxylase, which converts
T20396	Levadopa Related Compound A 6-Hydroxydopa, L-,L-Hydroxydopa
	Levadopa Related Compound A is the 6-hydroxy derivative of the amino acid L-DOPA with neurotoxic properties. Exogenously administered 6-Hydroxy-L-DOPA is biotransformed by an amino acid decarboxylase to the highly potent and catecholamine-selective neurot
T38221	N,N-Dipropyldopamine (hydrobromide)
	N,N-Dipropyldopamine is a dopamine receptor agonist.1,2,3 It decreases dihydrophenylalanine (DOPA) levels in the limbic forebrain and striatum of reserpinized rats (ED50s = 25 and 20 μmol/kg, respectively), as well as reduces homovanillic acid levels in rat striatum when administered at a dose of 80 μmol/kg.1 N,N-Dipropyldopamine (0.5-16 mg/kg) reduces spontaneous locomotor activity in mice, an effect that can be reversed by the antipsychotic spiroperidol.2,3
T62946	Dopamine D3 receptor antagonist-2
	Dopamine D3 receptor antagonist-2 是一种多巴胺 D3 受体选择性（Ki= 2.16 nM）或多靶点双配体，对中枢神经系统疾病表现出潜在作用。
T64024	Dopamine D3 receptor antagonist-1
	Dopamine D3 receptor antagonist-1 是一种多巴胺 D3受体选择性或多靶点配体，其 Ki 值为 1.58 nM，对中枢神经系统疾病表现出治疗潜能。
T75537	N-Acetyldopamine dimer-2
	N-Acetyldopamine dimer-2（compound 2）是一种从蝉皮黄色粉末中分离出来的N-acetyldopamine二聚体，具有抗氧化和抗炎作用。它能抑制氧化低密度脂蛋白（LDL）的氧化、ROS的生成、NO的生成以及NF-κB的活性。
T83776	Dopamine D3 Receptor Agonist 13a
	Dopamine D3 受体激动剂13a是一种Dopamine D3 受体激动剂。该化合物选择性地与Dopamine D3 受体结合，相较于Dopamine D1、D2和D4受体(Kis = 0.14、4,600、2.85和756 nM，分别)具有更高的亲和力，并且还能与血清素(5-HT)受体亚型5-HT1A、5-HT2A、5-HT2B和5-HT2C(Kis = 6、54、1.47和252 nM，分别)结合；然而，它是Dopamine D2受体的部分激动剂(EC50 = 2.26 nM，在G蛋白招募分析中)并且作为Dopamine D3受体的拮抗剂(IC50 = 4.62 nM)。在大鼠身上，当剂量为3 mg/kg时，Dopamine D3 受体激动剂13a能减少可卡因自我给药。
T70155	Fenoldopam hydrochloride
	Fenoldopam hydrochloride is a selective D1-like dopamine receptor partial agonist. It acts as a vasodilator in vivo and does not readily cross the blood-brain barrier. Fenoldopam HCl is also an α2-adrenoceptor antagonist in vitro.
T71779	Fenoldopam hydrobromide
	Fenoldopam hydrobromide is a Dopamine D1-receptor agonist that acts as an antihypertensive.
T60917	Dopamine D4 receptor antagonist-1
	Dopamine D4 receptor antagonist-1 可用于研究精神分裂症。Dopamine D4 receptor antagonist-1 是多巴胺D4受体 (DRD4) 的选择性拮抗剂。Dopamine D4 receptor antagonist-1 对Hd4.2的Ki 值为 9.0 nM。
T60241	N-Methyldopamine hydrochloride
	N-Methyldopamine hydrochloride 是肾上腺素在肾上腺髓质中的前体。N-Methyldopamine hydrochloride 是多巴胺 (DA) 的修饰物，并保留了对 DA1 受体 (DA1 receptor) 的激动剂活性。N-Methyldopamine hydrochloride 具有普遍的表面包覆和利用表面儿茶酚进行二次反应的能力。N-Methyldopamine hydrochloride 可用于心力衰竭的研究。
T68937	Carbidopa hydrochloride
	Carbidopa hydrochloride is a drug given to people with Parkinson's disease in order to inhibit peripheral metabolism of levodopa. This property is significant in that it allows a greater proportion of peripheral levodopa to cross the blood–brain barrier for central nervous system effect.
T68676	Ciladopa (free base)
	Ciladopa (free base) is a dopamine agonist with a similar chemical structure to dopamine. It was under investigation as an antiparkinsonian agent but was discontinued due to concerns of tumorogenesis in rodents.
T35298	Zelandopam hydrochloride YM 435,YM435,YM-435
	Zelandopam hydrochloride is a biochemical.
T15339	Foscarbidopa Carbidopa 4′-monophosphate	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Foscarbidopa is a prodrug of Carbidopa. It acts as a dopamine receptor agonist.
T22779	Fenoldopam	Others	Others
	Fenoldopam is a selective D1-like dopamine receptor partial agonist (EC50 = 57 nM).
TMIH-0049	3-O-Methyldopa-d3
	3-O-Methyldopa-d3 是 3-O-Methyldopa 的氘代化合物。3-O-Methyldopa 的 CAS 号为 300-48-1。
T68204	Foslevodopa
	Foslevodopa is a dopamine receptor agonist.
T126370	Dopacetamide
	Dopacetamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126370，CAS号为 1129-53-9。
T74081	N-β-alanyldopamine hydrochloride
	N-β-alanyldopamine hydrochloride (NBAD hydrochloride) 是血淋巴中多巴胺的主要衍生物。
T62530	N-Arachidonyldopamine NADA	Cannabinoid Receptor	GPCR/G Protein
	N-Arachidonyldopamine (NADA) 是一种选择性的、强效的内源性 CB1 受体激动剂 (Ki: 250 nM)。N-Arachidonyldopamine 也是一种有效的、选择性 TRPV1 激动剂，其 EC50 值 ~50 nM。
T131397	8-Oxopseudopalmatine
	8-Oxopseudopalmatine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131397。
T36206	Methyldopate
	Methyldopate is an ethyl ester prodrug form of methyldopa , a dopamine decarboxylase inhibitor that has antihypertensive activity in vitro and in vivo., Formulations containing methyldopate have been used in the treatment of hypertension.
TMIH-0340	Methyldopa-d3
	Methyldopa-d3 是 Methyldopa 的氘代化合物。Methyldopa 的 CAS 号为 6014-30-8。
T37533	DOPAL
	DOPAL is an aldehyde product of the oxidative deamination of dopamine by monoamine oxidase.[1] It can be further oxidized to 3,4-dihydroxyphenylacetic acid (DOPAC) by aldehyde dehydrogenase (ALDH) and, to a lesser extent reduced to 3,4-dihydroxyphenyl ethanol (DOPET). DOPAL is toxic to neurons.[2],[3] It can also oligomerize and precipitate α-synuclein, an event associated with Parkinson's disease.[2] Mice lacking cytosolic and mitochondrial forms of ALDH display increased levels of DOPAL as wel...
T20133	Methyldopate hydrochloride Aldomet Ester hydrochloride,Aldomet,Methyldopate HCl,Methyldopa ethyl ester hydrochloride
	Methyldopate HCl is an agent of antihypertensive.
T60369	Droxidopa hydrochloride
	Droxidopa (L-DOPS) hydrochloride 是一种有效的、具有口服活性的去甲肾上腺素前体。Droxidopa hydrochloride 可增加站立血压，改善直立性低血压症状并提高站立能力。Droxidopa hydrochloride 具有研究神经源性直立性低血压（nOH）和替代性多动症 (注意缺陷多动障碍) 的潜力[3]。
T69105	Methyldopa anhydrous
	Methyldopa anhydrous is a Central alpha-2 Adrenergic Agonist. The mechanism of action of methyldopa anhydrous is as an Adrenergic alpha2-Agonist.
T29213	Zelandopam free base YM-435,YM435,MYD-37,MYD37,Zelandopam
	Zelandopam is a dopamine D1 agonist. Zelandopam is a potent stimulant of pancreatic exocrine secretion by acting on DA D1 receptors of the pancreas in dogs. Intravenous administration of Zelandopam produces renal vasodilating and diuretic/natriuretic effe
T62528	Dopamine D3 receptor ligand-1
	Dopamine D 3 receptor ligand 是一种有效的、选择性的、高亲和力的多巴胺 D3受体配体，对 D3 (Ki: 8 nM) 的选择性是 D2 (Ki: 715 nM) 的89倍。
T41192	CNV Dopamine
	CNV Dopamine is a carboxynitroveratryl (CNV)-caged dopamine; releases dopamine upon ultraviolet light stimulation (365 nm). Induces dopaminergic currents upon photolysis in brain slices expressing wild-type or GFP-labeled D2receptors. Displays no decrease in current (rundown) with UV light flash duration of up to 100 ms. Pharmacologically inactive prior to photolysis.

化合物

6-Hydroxy-DOPA

Cat.No: T26396

Synonym: 6-羟基-DL-多巴,6-Hydroxy-DL-DOPA

Target: DNA/RNA Synthesis

Cat.No: T31570

Synonym: DPBX L-Dopa

Cat.No: T37605

Etilevodopa hydrochloride

Cat.No: T24047

Synonym: Levodopa ethyl ester,Etilevodopa HCl, L-DOPA ethyl ester

Target: Others, Dopamine Receptor, Drug Metabolite

Cat.No: T23275

Target: Others

3-O-methyl-L-DOPA (hydrate)

Cat.No: T36122

Fluorodopa F 18

Cat.No: T31823

Synonym: Fluorodopa (18F),6-(18F)Fluoro-L-DOPA,F-DOPA,L-6-(18F)Fluoro-DOPA,6-(18F)Fluorodopamine

Cat.No: T20700

Target: Others

Cat.No: T34589

Synonym: d3-L-DOPA,deuldopa,deuterated levodopa,SD1077

[18F]-Labeled L-dopa precursor

Cat.No: T74180

Carbidopa monohydrate

Cat.No: T2148

Synonym: Carbidopa Hydrate,S(-)-Carbidopa,卡比多巴水合物

Target: Decarboxylase, Aryl Hydrocarbon Receptor

Methyldopa hydrate

Cat.No: T5954

Synonym: L-甲基多巴,Alpha-Methyldopa Sesquihydrate,L-(-)-α-Methyldopa hydrate,MK-351 hydrate,Methyldopa Sesquihydrate

Target: Dopamine Receptor, Adrenergic Receptor

5-Hydroxydopamine hydrochloride

Cat.No: T13512

Target: Antifungal

Dopamine D2 receptor antagonist-1

Cat.No: T11077

Target: Others

Fenoldopam mesylate

Cat.No: T6835

Synonym: Fenoldopam methanesulfonate,SKF-82526 mesylate,Corlopam mesylate,mesylate,SKF 82526,非诺多泮甲磺酸盐

Target: Dopamine Receptor

Oxidopamine hydrochloride

Cat.No: T12352

Synonym: 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride,6-羟基多巴胺盐酸盐

Target: Mitophagy, Dopamine Receptor, Autophagy

Dopamine D2 receptor agonist-2

Cat.No: T60075

Synonym: Dopamine D2 Receptor

Target: Dopamine Receptor

Cat.No: T2547

Synonym: 屈昔多巴,屈西多巴,SM5688,DOPS,L-DOPS

Target: Adrenergic Receptor

Oxidopamine hydrobromide

Cat.No: T12352L

Synonym: 6-Hydroxydopamine hydrobromide,6-羟基多巴胺氢溴酸盐,6-OHDA hydrobromide

Target: Mitophagy, Dopamine Receptor, Autophagy

Methyldopa hydrochloride

Cat.No: T15701

Synonym: L-(-)-α-Methyldopa hydrochloride,MK-351 hydrochloride

Target: Others

Levadopa Related Compound A

Cat.No: T20396

Synonym: 6-Hydroxydopa, L-,L-Hydroxydopa

N,N-Dipropyldopamine (hydrobromide)

Cat.No: T38221

Dopamine D3 receptor antagonist-2

Cat.No: T62946

Dopamine D3 receptor antagonist-1

Cat.No: T64024

N-Acetyldopamine dimer-2

Cat.No: T75537

Dopamine D3 Receptor Agonist 13a

Cat.No: T83776

Fenoldopam hydrochloride

Cat.No: T70155

Fenoldopam hydrobromide

Cat.No: T71779

Dopamine D4 receptor antagonist-1

Cat.No: T60917

N-Methyldopamine hydrochloride

Cat.No: T60241

Carbidopa hydrochloride

Cat.No: T68937

Ciladopa (free base)

Cat.No: T68676

Zelandopam hydrochloride

Cat.No: T35298

Synonym: YM 435,YM435,YM-435

Cat.No: T15339

Synonym: Carbidopa 4′-monophosphate

Target: Dopamine Receptor

Cat.No: T22779

Target: Others

3-O-Methyldopa-d3

Cat.No: TMIH-0049

Cat.No: T68204

Cat.No: T126370

N-β-alanyldopamine hydrochloride

Cat.No: T74081

N-Arachidonyldopamine

Cat.No: T62530

Synonym: NADA

Target: Cannabinoid Receptor

8-Oxopseudopalmatine

Cat.No: T131397

Cat.No: T36206

Cat.No: TMIH-0340

Cat.No: T37533

Methyldopate hydrochloride

Cat.No: T20133

Synonym: Aldomet Ester hydrochloride,Aldomet,Methyldopate HCl,Methyldopa ethyl ester hydrochloride

Droxidopa hydrochloride

Cat.No: T60369

Methyldopa anhydrous

Cat.No: T69105

Zelandopam free base

Cat.No: T29213

Synonym: YM-435,YM435,MYD-37,MYD37,Zelandopam

Dopamine D3 receptor ligand-1

Cat.No: T62528

Cat.No: T41192

Cat. No.	Product Name	Target	Signaling Pathways
T15138	DL-Dopa	Endogenous Metabolite	Metabolism
	DL-Dopa 是一种苯丙氨酸 β-羟基化衍生物。
T0848	L-DOPA 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine	Dopamine Receptor; Endogenous Metabolite	GPCR/G Protein; Metabolism; Neuroscience
	L-DOPA (Levodopa) 是的神经递质多巴胺的代谢前体，具有口服活性。Levodopa 能够透过血脑屏障，并在大脑中转化为多巴胺。Levodopa 具有抗痛觉过敏作用。Levodopa 还具有帕金森氏病的研究潜力。
T26288	Clovamide trans-Clovamide,N-trans-Caffeoy-L-dopa	Apoptosis; Influenza Virus; ROS; Antibacterial	Apoptosis; Immunology/Inflammation; Microbiology/Virology
	Clovamide (trans-Clovamide) 是一种天然存在的咖啡酰结合物，具有抗菌、抗炎、抗氧化和神经保护作用。它是一种极好的活性氧和氧自由基清除剂。
T15255	Etilevodopa Levodopa ethyl ester,L-DOPA ethyl ester	Others	Others
	Etilevodopa is an ethyl-ester prodrug of Levodopa which is used for the treatment of Parkinson's disease (PD). It is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Levodopa is the direct precursor of dop
T0505	Methyldopa L-(-)-α-Methyldopa,MK-351,甲基多巴	Dopamine Receptor; Adrenergic Receptor	GPCR/G Protein; Neuroscience
	L-(-)-α-Methyldopa (MK-351) 是一种前药，在中枢神经系统中被代谢成 α-Methylepinephrine。它是 α-肾上腺素能激动剂，对 α2- adrenergic receptors 有选择性。
T1644	Dopamine hydrochloride 盐酸多巴胺,Dopamine HCl,ASL279	Ferroptosis; Dopamine Receptor; 5-HT Receptor; Endogenous Metabolite	Apoptosis; GPCR/G Protein; Metabolism; Neuroscience
	Dopamine hydrochloride (ASL279) 是在脑黑质、脑腹侧被盖区和下丘脑中产生的一种天然儿茶酚胺，由二羟基苯丙氨酸脱羧形成，是去甲肾上腺素和肾上腺素的前体。它通过 D2 多巴胺受体来诱导 VEGFR2 的内吞作用，有促进血管生成活性。
T6795	Carbidopa 卡比多巴,(S)-(-)-Carbidopa,Lodosyn	Decarboxylase; Aryl Hydrocarbon Receptor	Immunology/Inflammation; Metabolism; Others
	Carbidopa (Lodosyn) 是一种选择性芳香烃受体(AhR)调节剂，是外周型脱羧酶抑制剂，抑制胰腺癌细胞和肿瘤生长，可用于帕金森病的研究。
T40158	N-acetyldopamine NADA,N-乙酰多巴胺
	N-acetyldopamine (NADA) is a catecholamine utilized by insects as a precursor for sclerotization, a process that strengthens their cuticle.
T73775	Dopamine 3-O-sulfate
	Dopamine 3-O-sulfate，一种主要存在于血浆中的化合物，可作为芳香族氨基酸脱羧酶(AADC)缺乏症的生物标志物。
TN6009	Pseudopalmatine
	Pseudopalmatine exhibits antiplasmodial activity. It also shows anti-acetylcholinesterase (AChE) activity, with IC50 values of 1.8uM.
T81710	N-Acetyldopamine dimer-3
	N-Acetyldopamine dimer-3 (compound 11)为Aspongopus chinensis中检出的天然化合物。
T3737	3-(2,4-Dihydroxyphenyl)propanoic acid 3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid	Tyrosinase	Proteases/Proteasome
	3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) 是竞争性酪氨酸酶 (tyrosinase) 抑制剂，可抑制 L-Tyrosine 和 DL-DOPA，IC50和 Ki 分别为 3.02 μM 和 11.5 μM。
T4S1962	beta-Asarone β-细辛脑,(Z)-1,2,4-三甲氧基-5-丙烯基苯;顺式细辛脑,Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin	NF-κB; JNK	MAPK; NF-κB
	beta-Asarone (Cis-Isoelemicin) 是一种石菖蒲中的主要成分，具有免疫抑制、促进安定、中枢神经系统抑制、降温等功能。它可透过血脑屏障，能够预防帕金森病。
TN1314	6-Hydroxykaempferol	Tyrosinase	Proteases/Proteasome
	6-Hydroxykaempferol is a competitive inhibitor of tyrosinase compared to L-DOPA, it shows also high antioxidant activities.
TMA2419	Catalponol	cAMP	GPCR/G Protein
	Catalponol can enhance dopamine biosynthesis by inducing TH activity and protect against L-DOPA-induced cytotoxicity in PC12 cells, which was mediated by the increased levels of cyclic AMP.
T75563	Vanicoside E
	Vanicoside E 是一种抗氧化和抗癌剂。Vanicoside E 抑制L-Tyrosine 和L-DOPA，IC50为 45.23 μM 和 189.96 μM。
TMA0003	Trans-caffeic acid	cAMP; Tyrosinase	GPCR/G Protein; Proteases/Proteasome
	Trans-caffeic acid stearyl ester is posited to inhibit melanogenesis signaling while suppressing cAMP levels and, subsequently, MC1R, MITF, tyrosinase, TRP-2 and TRP-1 down-regulation, resulting in the suppression of tyrosinase activity, DOPA oxidase activity and melanin synthesis.
TN3607	Catalpalactone	cAMP	GPCR/G Protein
	Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. Catalpalactone can inhibit dopamine biosynthesis by

天然产物

Cat.No: T15138

Target: Endogenous Metabolite

Cat.No: T0848

Synonym: 左旋多巴,Levodopa,3,4-Dihydroxyphenylalanine

Target: Dopamine Receptor, Endogenous Metabolite

Cat.No: T26288

Synonym: trans-Clovamide,N-trans-Caffeoy-L-dopa

Target: Apoptosis, Influenza Virus, ROS, Antibacterial

Cat.No: T15255

Synonym: Levodopa ethyl ester,L-DOPA ethyl ester

Target: Others

Cat.No: T0505

Synonym: L-(-)-α-Methyldopa,MK-351,甲基多巴

Target: Dopamine Receptor, Adrenergic Receptor

Dopamine hydrochloride

Cat.No: T1644

Synonym: 盐酸多巴胺,Dopamine HCl,ASL279

Target: Ferroptosis, Dopamine Receptor, 5-HT Receptor, Endogenous Metabolite

Cat.No: T6795

Synonym: 卡比多巴,(S)-(-)-Carbidopa,Lodosyn

Target: Decarboxylase, Aryl Hydrocarbon Receptor

N-acetyldopamine

Cat.No: T40158

Synonym: NADA,N-乙酰多巴胺

Dopamine 3-O-sulfate

Cat.No: T73775

Pseudopalmatine

Cat.No: TN6009

N-Acetyldopamine dimer-3

Cat.No: T81710

3-(2,4-Dihydroxyphenyl)propanoic acid

Cat.No: T3737

Synonym: 3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid

Target: Tyrosinase

Cat.No: T4S1962

Synonym: β-细辛脑,(Z)-1,2,4-三甲氧基-5-丙烯基苯;顺式细辛脑,Cis-Isoasarone,Cis-Asarone,Cis-Isoelemicin

Target: NF-κB, JNK

6-Hydroxykaempferol

Cat.No: TN1314

Target: Tyrosinase

Cat.No: TMA2419

Target: cAMP

Cat.No: T75563

Trans-caffeic acid

Cat.No: TMA0003

Target: cAMP, Tyrosinase

Cat.No: TN3607

Target: cAMP

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