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Targets Recommended: NF-κB

34

抑制剂 & 化合物

2

天然产物

47

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T17157 TRAF-STOP inhibitor 6877002

CD40-TRAF6 inhibitor

NF-κB NF-κB
TRAF-STOP inhibitor 6877002 (CD40-TRAF6 inhibitor)是一种 CD40-TRAF6 相互作用的选择性抑制剂,可以抑制 RAW 细胞中 NF-κB 活化。TRAF-STOP 6877002 可阻止小鼠动脉粥样硬化的恶化,减少白细胞募集和巨噬细胞的活化,减少动脉粥样硬化斑块中的巨噬细胞增殖。
T76830 Teneliximab

Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819

TNF Apoptosis
Teneliximab (Chi220) 是一种嵌合的单克隆抗体,也是一种肿瘤坏死因子受体超家族成员5(CD40)抑制剂,可阻断CD40-CD40L 的相互作用。Teneliximab 通过CD40 和外周B细胞损耗发挥部分激动剂活性,可用于研究器官移植排斥和类风湿关节炎。
T78312 Cifurtilimab

SEA-CD40

Cifurtilimab(SEA-CD40)是一种具有抗癌活性的人源化抗CD40 IgG1单克隆抗体。
T82858 Bleselumab

ASKP 1240,Anti-Human CD40 Recombinant Antibody

Bleselumab (ASKP 1240)为人源化抗-CD40单克隆抗体,通过高亲和力(Kd: 0.24 nM)与CD40结合,阻断CD40CD40L配体的相互作用,从而抑制免疫反应,用于预防器官移植排斥。
T9926 Omalizumab

Others Others
Omalizumab 是针对人免疫球蛋白 E 的重组人源化单克隆抗体(KD:0.393 nM)。它能够结合人 FcγRIIb 受体(KD:6.37 uM)。它对持续性过敏性哮喘具有潜在的研究价值。
T11096 DRI-C21045

NF-κB NF-κB
DRI-C21045 是一种有效的 CD40-CD40L 协同刺激蛋白-蛋白质相互作用的选择性抑制剂,IC50 为 0.17 μM。它显示对 CD40L 诱导的 NF-κB 活化和 B 细胞增殖的浓度依赖性抑制,IC50分别为 17.1 μM 和 4.5 μM。
T79194 DRI-C25441

DRI-C25441, 作为一种CD40CD40L相互作用的有效阻断剂,其IC50为0.36 μM,能够抑制同种异体抗原诱导的免疫反应。
T73866 BIO8898

BIO8898 是一种有效的 CD40-CD154抑制剂。BIO8898 抑制可溶性 CD40L 与 CD40-Ig 的结合,IC50值为 25 µM。BIO8898 抑制 CD40L 诱导的细胞凋亡(apoptosis)。
T73865 (Rac)-BIO8898

(Rac)-BIO8898 是一种 CD40-CD154共刺激相互作用抑制剂。(Rac)-BIO8898 抑制 CD154 与 CD40-Ig 结合,IC50为 25 μM。
T76729 Lucatumumab

Lucatumumab (HCD122) 是一种全人抗 CD40拮抗剂单克隆抗体,可阻断 CD40/ CD40L 介导的信号通路。Lucatumumab 可有效介导抗体依赖性细胞介导的细胞毒性 (ADCC) 和肿瘤细胞清除,可用于顽固性淋巴瘤、慢性淋巴细胞白血病 (CLL) 和多发性骨髓瘤研究。
T77035 Inezetamab

Inezetamab 是一种双特异性抗CD40和抗MSLNIgG1单克隆抗体。
T24808 SMI-6860766

TRAFSTOP 6860766,TRAF-STOP 6860766,SMI 6860766,TRAFSTOP6860766,SMI6860766

SMI-6860766 is a CD40-Traf6 interactions blocker that acts by ameliorating the complications of diet-induced obesity in mice.
T78251 Sotigalimab

Sotigalimab 是一种CD40激动性单克隆抗体,适用于转移性胰腺癌研究。
T77143 Ravagalimab

Ravagalimab (ABBV-323) 是一种CD40拮抗剂(EC50: 3.7 nM)。Ravagalimab 可用于克罗恩病的研究。
T70214 BMS-986202

BMS-986202 is a novel Tyk2 inhibitor, binding to Tyk2 JH2, showing efficacies for IL-23-driven acanthosis, anti-CD40-induced colitis, and spontaneous lupus.
T82615 Dalnicastobart

LVGN-7409

Dalnicastobart (LVGN-7409) 是一种针对CD40/TNFRSF5的人源化IgG1κ单克隆抗体。
T77013 Frexalimab

Frexalimab (SAR441344; INX-021) 是一种靶向 CD40配体 (CD40L) 的单克隆抗体。Frexalimab 具有用于多发性硬化症研究的潜力。
T78250 Selicrelumab

Selicrelumab是一种针对CD40的抗体激动剂,能够诱导肿瘤微环境的改变,适用于胰腺癌及肿瘤新辅助治疗的研究。
T82320 Giloralimab

ABBV-927

Giloralimab (ABBV-927)为一种抗CD40激动性单克隆抗体,展现出用于癌症研究的潜力。
T61810 Anti-inflammatory agent 16

Anti-inflammatory agent 16 (compound 14) is a highly effective peptidomimetic with potent anti-inflammatory properties. It effectively reduces the expression levels of TNFα, NO, CD40, and CD86 [1].
T30669 C.I. Mordant Brown 1

NSC-326197,NSC 326197,NSC326197

C.I. Mordant Brown 1 是一种偶氮染料,λmax 为 373 nm、487 nm (2nd)。C.I. Mordant Brown 1 也可以抑制CD40-CD154 共刺激蛋白-蛋白互作。
T79193 DRI-C21041

DRI-C21041,作为一种针对CD40/CD40L相互作用的抑制剂,其IC50为0.31 μM,能够抑制由同种异体抗原诱导的免疫反应。
T78198 DRI-C21041 (DIEA)

DRI-C21041 (DIEA)是一种IC50值为0.31 μM的CD40/CD40L相互作用抑制剂,能够抑制同种异体抗原诱导的免疫反应。
T75130 Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br

Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br 作为一种Drug-linker conjugates for ADC,主要用于抗CD40抗体活性分子偶联物 (ADCs) 的合成, 充当反应试剂。
T75016 Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal

Glucocorticoid receptoragonist-1 phosphate Ala-Ala-Mal 是一种糖皮质激素受体激动剂。Glucocorticoid receptoragonist-1 phosphate Ala-Ala-Mal 可用于抗 CD40抗体偶联活性分子(ADC)。Glucocorticoid receptoragonist-1 phosphate Ala-Ala-Mal 可用于炎症和免疫调节的研究。
T76984 Tecaginlimab

Tecaginlimab (BNT-312) 是一种 Fc 惰性双特异性抗体,用于CD40和4-1BB 的双重靶向和条件刺激。Tecaginlimab 可以增强肿瘤特异性免疫的启动和再激活。
T77043 Iscalimab

Iscalimab (CFZ-533) 是一种非耗竭性 IGg1单克隆抗体,靶向 CD40(KD: 0.3 nM)。Iscalimab 可用于 Graves 甲状腺功能亢进症和自身免疫性疾病的研究。
T82954 ATAC21

ATAC21是一种连接子免疫刺激化合物,它通过含琥珀酰亚胺基团的稳定型马来酰亚胺-PEG4连接子与免疫刺激化合物结合而成。ATAC21能够与SBT-040(抗CD40抗体)结合,形成具有免疫激活作用的偶联物。
T81022 Tegoprubart

Tegoprubart为针对CD40配体(CD40L)的单克隆抗体,该配体为共刺激介质的核心。通过抑制CD40L,可减弱细胞与抗体介导的免疫反应,促进免疫环境趋向耐受性。在移植动物模型中,Tegoprubart已展现出体内活性。
T76677 Dacetuzumab

Dacetuzumab (SGN-40) 是一种人源化的 IgG1,抗 CD40单克隆抗体,具有抗淋巴瘤活性。Dacetuzumab 通过免疫效应作用(抗体依赖性细胞毒性和吞噬作用[ADCC/ADCP]) 杀死肿瘤细胞。Dacetuzumab ((SGN-40) 可用于多发性骨髓瘤研究。
T76834 Toralizumab

Toralizumab (IDEC-131) 是一种针对 CD40L (CD154)的人源化单克隆抗体 (mAb),由人 γ1 重链和人 kappa 轻链组成。Toralizumab 特异性结合 T 细胞上的人 CD40L,从而阻止 CD40信号传导。Toralizumab 是一种免疫抑制剂,具有用于活跃的系统性红斑狼疮 (SLE) 研究的潜力。
T77090 Mitazalimab

Mitazalimab(ADC-1013; JNJ-64457107)是一种FcγR依赖性CD40激动剂,以肿瘤导向活性为特征。该化合物通过激活抗原呈递细胞(如树突状细胞[DC]),启动肿瘤反应性T细胞,进而诱导肿瘤特异性T细胞浸润并杀死肿瘤,有效重塑肿瘤浸润性骨髓微环境。
T37787 10-Nitrolinoleic acid

10-Nitrolinoleate is the product of nitration of linoleate by NO-derived reactive species. Other nitrolinoleates detected in human plasma and urine include 9-, 12-, and 13-nitrolinoleate. Nitrolinoleates activate peroxisome proliferator-activated receptor γ (PPARγ; Ki = 133 nM), inducing CD36 expression in macrophages, adipocyte differentiation, and glucose uptake. Nitrolinoleates can also be metabolized by smooth muscle cells to produce nitrite derivatives which in turn form NO, leading to incr...
T36984 Cyclic di-IMP (sodium salt)

Cyclic di-IMP (sodium salt) (c-di-IMP) is a synthetic second messenger structurally related to the bacterial second messengers cyclic di-GMP and cyclic di-AMP . C-di-IMP has adjuvant properties when co-administered with antigens in vitro and by mucosal routes in vivo. C-di-IMP enriches the population of MHC class I and II, CD80, CD86, CD40, and CD54 positive dendritic cells derived from murine bone marrow. It also stimulates macrophages at 500 ng/ml. Mice immunized with β-galactosidase (β-gal) p...

化合物

TRAF-STOP inhibitor 6877002
Cat.No: T17157
Synonym: CD40-TRAF6 inhibitor
Target: NF-κB
Teneliximab
Cat.No: T76830
Synonym: Chi220,Anti-Human CD40 Recombinant Antibody,BMS 224819
Target: TNF
Cifurtilimab
Cat.No: T78312
Synonym: SEA-CD40
Target:
Bleselumab
Cat.No: T82858
Synonym: ASKP 1240,Anti-Human CD40 Recombinant Antibody
Target:
Omalizumab
Cat.No: T9926
Synonym:
Target: Others
DRI-C21045
Cat.No: T11096
Synonym:
Target: NF-κB
DRI-C25441
Cat.No: T79194
Synonym:
Target:
BIO8898
Cat.No: T73866
Synonym:
Target:
(Rac)-BIO8898
Cat.No: T73865
Synonym:
Target:
Lucatumumab
Cat.No: T76729
Synonym:
Target:
Inezetamab
Cat.No: T77035
Synonym:
Target:
SMI-6860766
Cat.No: T24808
Synonym: TRAFSTOP 6860766,TRAF-STOP 6860766,SMI 6860766,TRAFSTOP6860766,SMI6860766
Target:
Sotigalimab
Cat.No: T78251
Synonym:
Target:
Ravagalimab
Cat.No: T77143
Synonym:
Target:
BMS-986202
Cat.No: T70214
Synonym:
Target:
Dalnicastobart
Cat.No: T82615
Synonym: LVGN-7409
Target:
Frexalimab
Cat.No: T77013
Synonym:
Target:
Selicrelumab
Cat.No: T78250
Synonym:
Target:
Giloralimab
Cat.No: T82320
Synonym: ABBV-927
Target:
Anti-inflammatory agent 16
Cat.No: T61810
Synonym:
Target:
C.I. Mordant Brown 1
Cat.No: T30669
Synonym: NSC-326197,NSC 326197,NSC326197
Target:
DRI-C21041
Cat.No: T79193
Synonym:
Target:
DRI-C21041 (DIEA)
Cat.No: T78198
Synonym:
Target:
Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Br
Cat.No: T75130
Synonym:
Target:
Glucocorticoid receptor agonist-1 phosphate Ala-Ala-Mal
Cat.No: T75016
Synonym:
Target:
Tecaginlimab
Cat.No: T76984
Synonym:
Target:
Iscalimab
Cat.No: T77043
Synonym:
Target:
ATAC21
Cat.No: T82954
Synonym:
Target:
Tegoprubart
Cat.No: T81022
Synonym:
Target:
Dacetuzumab
Cat.No: T76677
Synonym:
Target:
Toralizumab
Cat.No: T76834
Synonym:
Target:
Mitazalimab
Cat.No: T77090
Synonym:
Target:
10-Nitrolinoleic acid
Cat.No: T37787
Synonym:
Target:
Cyclic di-IMP (sodium salt)
Cat.No: T36984
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T0948L Corticosterone

皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)

Glucocorticoid Receptor; Endogenous Metabolite Endocrinology/Hormones; Metabolism
Corticosterone (Kendall's compound B) 是一种肾上腺皮质类固醇,有盐皮质激素和糖皮质激素的活性,具有口服活性。Corticosterone 参与体内能量、免疫反应和应激反应的调节。
TN1998 Notoginsenoside T5

三七皂苷T5

MMP Proteases/Proteasome
Total panax notoginsenosides (TPNS) are the main active ingredients in San-Chi, the root of(Burk) F.H. Chen, which belongs to the Araliaceae family and has been used in traditional Chinese medicine to treat atherosclerosis;TPNS can prevent atherosclerosis

天然产物

Corticosterone
Cat.No: T0948L
Synonym: 皮质酮,17-Deoxycortisol,11β,21-Dihydroxyprogesterone,Kendall's compound B,肾上腺酮,Corticosterone (From plants)
Target: Glucocorticoid Receptor, Endogenous Metabolite
Notoginsenoside T5
Cat.No: TN1998
Synonym: 三七皂苷T5
Target: MMP
Cat. No. Product Name Species Expression System
TMPY-03203 CD40 Protein, Rat, Recombinant (His)

CD40 molecule, TNF receptor superfamily me...

Rat HEK293 Cells
CD40 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.6 kDa and the accession number is A0A8I6A2T5.
TMPY-02022 CD40 Ligand Protein, Human, Recombinant (hFc)

HIGM1,IGM,gp39,CD40L,T-BAM,CD...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.8 kDa and the accession number is P29965.
TMPY-01181 CD40 Protein, Human, Recombinant (His)

CDW40,CD40 molecule, TNF...

Human HEK293 Cells
CD40 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.7 kDa and the accession number is A0A0S2Z3C7.
TMPY-05957 CD40 Protein, Mouse, Recombinant (His)

Bp50,HIGM1,TRAP,T-BAM,GP39,AI326936,p50,IGM,CD4...

Mouse HEK293 Cells
CD40 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.81 kDa and the accession number is P27512-1.
TMPY-03542 CD40 Ligand Protein, Rhesus, Recombinant (hFc)

CD40 ligand

Rhesus HEK293 Cells
CD40 Ligand Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.7 kDa and the accession number is A0A8J8XRR8.
TMPY-03301 CD40 Ligand Protein, Rat, Recombinant (hFc)

CD40 ligand

Rat HEK293 Cells
CD40 Ligand Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession number is Q9Z2V2.
TMPY-04086 CD40 Ligand Protein, Canine, Recombinant

CD40 ligand

Canine HEK293 Cells
CD40 Ligand Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16 kDa and the accession number is O97626.
TMPY-04065 CD40 Ligand Protein, Canine, Recombinant (mFc)

CD40 ligand

Canine HEK293 Cells
CD40 Ligand Protein, Canine, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 42.5 kDa and the accession number is O97626.
TMPY-03211 CD40 Protein, Rhesus, Recombinant (hFc)

CD40 molecule, TNF receptor superfamily me...

Rhesus HEK293 Cells
CD40 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is F6SNI1.
TMPY-04089 CD40 Protein, Canine, Recombinant (His)

CD40 molecule, TNF receptor superfamily me...

Canine HEK293 Cells
CD40 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q7YRL5.
TMPY-06687 CD40 Ligand Protein, Mouse, Recombinant (His)

IGM,IMD3,TRAP,Ly62,CD40-L,Tnfsf5,CD

Mouse HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17.37 kDa and the accession number is P27548.
TMPY-03212 CD40 Protein, Rhesus, Recombinant (His)

CD40 molecule, TNF receptor superfamily me...

Rhesus HEK293 Cells
CD40 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.7 kDa and the accession number is F6SNI1.
TMPY-03944 CD40 Protein, Canine, Recombinant

CD40 molecule, TNF receptor superfamily me...

Canine HEK293 Cells
CD40 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 19.9 kDa and the accession number is Q7YRL5.
TMPJ-00634 CD40 Protein, Cynomolgus, Recombinant (His)

CDw40,TNFRSF5,B-Cell Surface Antigen C...

Cynomolgus HEK293 Cells
CD40 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 28-30 KDa and the accession number is G7PG38.
TMPJ-01420 CD40 Protein, Cynomolgus, Recombinant (hFc)

Tumor Necrosis Factor Receptor Superfamily member 5,B-Cell S...

Cynomolgus HEK293 Cells
CD40 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 48-70 KDa and the accession number is XP_005569275.1.
TMPY-03907 CD40 Protein, Canine, Recombinant (hFc)

CD40 molecule, TNF receptor superfamily me...

Canine HEK293 Cells
CD40 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.1 kDa and the accession number is Q7YRL5.
TMPY-03083 CD40 Protein, Rat, Recombinant (hFc)

CD40 molecule, TNF receptor superfamily me...

Rat HEK293 Cells
CD40 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is Q4QQW2.
TMPK-00170 CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated

CD40 antigen,  TNFRSF5,CD40

Human HEK293 Cells
CD40 is a costimulatory protein found on antigen presenting cells and is required for their activation. The binding of CD154 (CD40L) on TH cells to CD40 activates antigen presenting cells and induces a variety of downstream effects.CD40 molecule is a potential target for cancer immunotherapy. There are number of completed and ongoing clinical trials where agonistic anti-CD40 monoclonal antibodies are employed to activate an anti-tumor T cell response via activation of dendritic cells.
TMPY-02793 CD40 Ligand Protein, Mouse, Recombinant (hFc)

gp39,CD40 ligand,IGM,Cd40

Mouse HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44.4 kDa and the accession number is P27548.
TMPH-03201 CD40 Ligand Protein, Rabbit, Recombinant (His)

TNLG8B,CD40 ligand,CD40-...

Rabbit P. pastoris (Yeast)
N/A. CD40 Ligand Protein, Rabbit, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.2 kDa and the accession number is G1SKP7.
TMPJ-00151 CD40 Ligand Protein, Human, Recombinant

CD40LG,CD40 Ligand,TRAP,...

Human E. coli
CD40 Ligand Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15 KDa and the accession number is P29965.
TMPH-03200 CD40 Ligand Protein, Rabbit, Recombinant (E. coli, His)

CD40LG,Tumor necrosis factor ligand superf...

Rabbit E. coli
N/A. CD40 Ligand Protein, Rabbit, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.2 kDa and the accession number is G1SKP7.
TMPJ-00153 CD40 Ligand Protein, Human, Recombinant (His & Flag)

CD40LG,Tumor Necrosis Factor Ligand Superf...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 19-24 KDa and the accession number is P29965.
TMPY-05359 CD40 Protein, Human, Recombinant (mFc)

Bp50,TNFRSF5,CDW40,p50,CD40

Human HEK293 Cells
CD40 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 45.5 kDa and the accession number is NP_001309350.1.
TMPJ-00150 CD40 Ligand Protein, Human, Recombinant (Mammalian)

CD40LG,Tumor Necrosis Factor Ligand Superf...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (Mammalian) is expressed in HEK293 mammalian cells. The predicted molecular weight is 16-18 KDa and the accession number is P29965.
TMPY-05614 CD40 Protein, Human, Recombinant (His & Avi), Biotinylated

Bp50,p50,CDW40,CD40 mole...

Human HEK293 Cells
CD40 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 22.4 kDa and the accession number is A0A0S2Z3C7.
TMPY-00482 CD40 Protein, Human, Recombinant (hFc)

CDW40,TNFRSF5,CD40 molec...

Human HEK293 Cells
CD40 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.2 kDa and the accession number is A0A0S2Z3C7.
TMPY-05599 CD40 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TNFRSF5,Bp50,CD40 molecule, TNF receptor s...

Human HEK293 Cells
CD40 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 47.7 kDa and the accession number is A0A0S2Z3C7.
TMPY-04994 CD40 Protein, Mouse, Recombinant (rFc)

HIGM1,IGM,IMD3,p50,GP39,T-BAM,Bp50,Tnfrsf5,TRAP,CD<...

Mouse HEK293 Cells
CD40 Protein, Mouse, Recombinant (rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 45.4 kDa and the accession number is P27512-1.
TMPY-05425 CD40 Protein, Mouse, Recombinant (hFc)

IGM,AI326936,TRAP,T-BAM,p50,IMD3,Tnfrsf5,HIGM1,GP39,Bp50,

Mouse HEK293 Cells
CD40 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.4 kDa and the accession number is P27512-1.
TMPJ-00152 CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated

CD40 Ligand,TNF-Related Activation Protein...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-6xHis-Avi tag. The predicted molecular weight is 23-28 KDa and the accession number is P29965.
TMPK-00860 CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)

IMD3,CD40LG,CD40L,IGM,TR...

Mouse HEK293 Cells
CD40 ligand or CD40L, also called CD154,  is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. CD40 Ligand Prote...
TMPY-01758 CD40 Ligand Protein, Human, Recombinant (His)

IMD3,hCD40L,CD40L,TRAP,T...

Human E. coli
CD40 Ligand Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.7 kDa and the accession number is P29965.
TMPY-05646 CD40 Ligand Protein, Human, Recombinant (hFc & Avi), Biotinylated

CD154,TRAP,CD40 ligand,gp39,h...

Human HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 44.7 kDa and the accession number is P29965.
TMPY-06024 CD40 Protein, Mouse, Recombinant (His & Avi), Biotinylated

T-BAM,CD40 molecule, TNF receptor superfam...

Mouse HEK293 Cells
CD40 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 22.5 kDa and the accession number is P27512-1.
TMPK-01398 CD40 Ligand Trimer Protein, Human, Recombinant (hFc)

CD40 Ligand,CD40LIGM,IGM...

Human HEK293 Cells
CD40 ligand or CD40L, also called CD154, is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells.
TMPK-00154 CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated

IMD3,TNFSF5IMD3,TRAP,CD40LIGM,CD<...

Human HEK293 Cells
CD40 ligand or CD40L, also called CD154,  is a protein that is primarily expressed on activated T cells and is a member of the TNF superfamily of molecules. It binds to CD40 (protein) on antigen-presenting cells (APC), which leads to many effects depending on the target cell type. In total CD40L has three binding partners: CD40, α5β1 integrin and αIIbβ3. CD154 acts as a costimulatory molecule and is particularly important on a subset of T cells called T follicular helper cells. CD40 Ligand Prote...
TMPJ-00920 CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)

TNFSF5,Tumor necrosis factor ligand superfamily member 5,

Mouse HEK293 Cells
CD40 Ligand, also known as TNFSF5, CD154, is a type II transmembrane glycoprotein member of the TNF superfamily. Mature mouse CD40 Ligand consists of a 22 amino acid (aa) cytoplasmic domain, a transmembrane segment, and a 214 aa extracellular region. CD40 Ligand is expressed as a homotrimer on platelets and activated T cells and B cells. It is up­regulated following stimulation of basophils, eosinophils, fibroblasts, mast cells, monocytes, natural killer cells, vascular endothelial cells, and sm...
TMPH-02439 CD40L Protein, Rhesus macaque, Recombinant (His)

CD40L,TNFSF5,CD40LG,...

Rhesus E. coli
CD40L Protein, Rhesus macaque, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 28.5 kDa and the accession number is P63304.
TMPH-01513 IGIP Protein, Human, Recombinant (His & KSI)

Human E. coli
Enhances IgA secretion from B-cells stimulated via CD40.
TMPH-01514 IGIP Protein, Human, Recombinant (His & TF)

Human Baculovirus Insect Cells
Enhances IgA secretion from B-cells stimulated via CD40.
TMPH-00540 Epstein-Barr virus (strain GD1) LMP1 Protein (His)

EBV P. pastoris (Yeast)
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein...
TMPH-00542 Epstein-Barr virus (strain Raji) LMP1 Protein (His)

EBV P. pastoris (Yeast)
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein...
TMPH-00541 Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc)

EBV E. coli
Acts as a CD40 functional homolog to prevent apoptosis of infected B-lymphocytes and drive their proliferation. Functions as a constitutively active tumor necrosis factor receptor that induces the activation of several signaling pathways, including those of the NF-kappa-B family. LMP1 signaling leads to up-regulation of antiapoptotic proteins and provide growth signals in latently infected cells. Interacts with host UBE2I and subsequently affects the sumoylation state of several cellular protein...
TMPY-02404 ADAM9 Protein, Mouse, Recombinant (His)

mKIAA0021,AU020942,ADAM metallopeptidase domain 9,Mltng,MDC9

Mouse HEK293 Cells
ADAM9 (A disintegrin and metallopeptidase domain 9, MDC9, meltrin gamma), is a type 1 transmembrane protein that has been associated with cancer development and metastases. ADAM9 is consistently overexpressed in various human cancers, and plays a role in tumorigenesis in mouse models. ADAM9 cleaves and releases a number of molecules with important roles in tumorigenesis and angiogenesis, such as EGF, FGFR2iiib, Tie-2, Flk-1, EphB4, CD40, VCAM-1, and VE-cadherin, and could represent a potential t...
TMPJ-00226 SLAMF1 Protein, Mouse, Recombinant (His)

signaling lymphocytic activation molecule,SLAM family member...

Mouse HEK293 Cells
Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been...
TMPH-02841 Prohibitin Protein, Mouse, Recombinant (His)

Mouse E. coli
Protein with pleiotropic attributes mediated in a cell-compartment- and tissue-specific manner, which include the plasma membrane-associated cell signaling functions, mitochondrial chaperone, and transcriptional co-regulator of transcription factors in the nucleus. Plays a role in adipose tissue and glucose Homeostasis in a sex-specific manner. Contributes to pulmonary vascular remodeling by accelerating proliferation of pulmonary arterial smooth muscle cells.; In the mitochondria, together with...

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CD40 Protein, Rat, Recombinant (His)
Cat.No: TMPY-03203
Species: Rat
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02022
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Human, Recombinant (His)
Cat.No: TMPY-01181
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-05957
Species: Mouse
Expression System: HEK293 Cells
CD40 Ligand Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03542
Species: Rhesus
Expression System: HEK293 Cells
CD40 Ligand Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03301
Species: Rat
Expression System: HEK293 Cells
CD40 Ligand Protein, Canine, Recombinant
Cat.No: TMPY-04086
Species: Canine
Expression System: HEK293 Cells
CD40 Ligand Protein, Canine, Recombinant (mFc)
Cat.No: TMPY-04065
Species: Canine
Expression System: HEK293 Cells
CD40 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03211
Species: Rhesus
Expression System: HEK293 Cells
CD40 Protein, Canine, Recombinant (His)
Cat.No: TMPY-04089
Species: Canine
Expression System: HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (His)
Cat.No: TMPY-06687
Species: Mouse
Expression System: HEK293 Cells
CD40 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-03212
Species: Rhesus
Expression System: HEK293 Cells
CD40 Protein, Canine, Recombinant
Cat.No: TMPY-03944
Species: Canine
Expression System: HEK293 Cells
CD40 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPJ-00634
Species: Cynomolgus
Expression System: HEK293 Cells
CD40 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPJ-01420
Species: Cynomolgus
Expression System: HEK293 Cells
CD40 Protein, Canine, Recombinant (hFc)
Cat.No: TMPY-03907
Species: Canine
Expression System: HEK293 Cells
CD40 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-03083
Species: Rat
Expression System: HEK293 Cells
CD40 Protein, Human, Recombinant (aa 21-193, His & Avi), Biotinylated
Cat.No: TMPK-00170
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02793
Species: Mouse
Expression System: HEK293 Cells
CD40 Ligand Protein, Rabbit, Recombinant (His)
Cat.No: TMPH-03201
Species: Rabbit
Expression System: P. pastoris (Yeast)
CD40 Ligand Protein, Human, Recombinant
Cat.No: TMPJ-00151
Species: Human
Expression System: E. coli
CD40 Ligand Protein, Rabbit, Recombinant (E. coli, His)
Cat.No: TMPH-03200
Species: Rabbit
Expression System: E. coli
CD40 Ligand Protein, Human, Recombinant (His & Flag)
Cat.No: TMPJ-00153
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Human, Recombinant (mFc)
Cat.No: TMPY-05359
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (Mammalian)
Cat.No: TMPJ-00150
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-05614
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00482
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05599
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Mouse, Recombinant (rFc)
Cat.No: TMPY-04994
Species: Mouse
Expression System: HEK293 Cells
CD40 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-05425
Species: Mouse
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPJ-00152
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (monomeric hFc)
Cat.No: TMPK-00860
Species: Mouse
Expression System: HEK293 Cells
CD40 Ligand Protein, Human, Recombinant (His)
Cat.No: TMPY-01758
Species: Human
Expression System: E. coli
CD40 Ligand Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPY-05646
Species: Human
Expression System: HEK293 Cells
CD40 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Cat.No: TMPY-06024
Species: Mouse
Expression System: HEK293 Cells
CD40 Ligand Trimer Protein, Human, Recombinant (hFc)
Cat.No: TMPK-01398
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein (Primary Amine Labeling), Human, Recombinant (His & Flag), Biotinylated
Cat.No: TMPK-00154
Species: Human
Expression System: HEK293 Cells
CD40 Ligand Protein, Mouse, Recombinant (aa 112-260, His)
Cat.No: TMPJ-00920
Species: Mouse
Expression System: HEK293 Cells
CD40L Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPH-02439
Species: Rhesus
Expression System: E. coli
IGIP Protein, Human, Recombinant (His & KSI)
Cat.No: TMPH-01513
Species: Human
Expression System: E. coli
IGIP Protein, Human, Recombinant (His & TF)
Cat.No: TMPH-01514
Species: Human
Expression System: Baculovirus Insect Cells
Epstein-Barr virus (strain GD1) LMP1 Protein (His)
Cat.No: TMPH-00540
Species: EBV
Expression System: P. pastoris (Yeast)
Epstein-Barr virus (strain Raji) LMP1 Protein (His)
Cat.No: TMPH-00542
Species: EBV
Expression System: P. pastoris (Yeast)
Epstein-Barr virus (strain AG876) LMP1 Protein (His & Myc)
Cat.No: TMPH-00541
Species: EBV
Expression System: E. coli
ADAM9 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-02404
Species: Mouse
Expression System: HEK293 Cells
SLAMF1 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00226
Species: Mouse
Expression System: HEK293 Cells
Prohibitin Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02841
Species: Mouse
Expression System: E. coli
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