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Search Results for " (±)-leucine "

115

抑制剂 & 化合物

18

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T64400	N-Cbz-L-Leucine N-[(Phenylmethoxy)carbonyl]-L-leucine	Amino Acids and Derivatives	Metabolism
	N-Cbz-L-Leucine (N-[(Phenylmethoxy)carbonyl]-L-leucine) 是一种亮氨酸衍生物，是一种常用的氨基酸保护基基。
T32811	L-Leucine-1-13C L-(1-13C)Leucine,(1-13C)Leucine	Endogenous Metabolite; mTOR	Metabolism; PI3K/Akt/mTOR signaling
	L-Leucine-1-13C (L-Leucine-13C)是一种 13C 标记的 L-Leucine，显著增强了 GLP-4 的亲和力。
TP1367	[D-Ala2]leucine-enkephalin (D-ALA2)-亮氨酸脑啡肽	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	[D-Ala2]leucine-enkephalin 是 δ 阿片类激动剂，是能长效抗降解的亮氨酸脑非肽，可用于研究 δ 阿片受体的信号通路。
T35785	N-Oleoyl Leucine
	N-Oleoyl leucine is an N-acyl amide generated by PM20D1 that uncouples mitochondrial respiration independent of uncoupling protein 1 (UCP1) in vitro. N-Oleoyl leucine (25 mg/kg, i.p.) decreases body weight and food intake, preferentially decreasing fat mass in a diet-induced obesity mouse model. It improves glucose homeostasis in a fasting glucose tolerance test and increases VO2 while slightly decreasing overall locomotor activity.
T7739	L-Leucyl-L-Leucine methyl ester hydrochloride Leu-Leu-ome hydrochloride	Others; Endogenous Metabolite	Metabolism; Others
	L-Leucyl-L-Leucine methyl ester hydrochloride (Leu-Leu-ome hydrochloride) 是一种人单核细胞或多形核白细胞产生的 L-亮氨酸甲酯的二肽缩合产物，能够选择性消除具有细胞毒性潜能的淋巴细胞，也能够诱导溶酶体途径应激。
T1387	Acetylleucine N-Acetyl-DL-leucine,乙酰亮氨酸,N-acetyl-L-leucine	Amino Acids and Derivatives	Metabolism
	Acetylleucine (N-Acetyl-DL-leucine) 是一种口服具有活性的化合物，可用于研究急性前庭眩晕，小脑性共济失调和眼球震颤。
T25676	Leucine thiorphan Leu-thiorphan
	Leucine thiorphan is an inhibitor of enkephalinase.
TP1264	Prolylleucine ((Benzyloxy)carbonyl)-L-prolyl-D-leucine	Others	Others
	Prolylleucine (((Benzyloxy)carbonyl)-L-prolyl-D-leucine) 是一种二肽，含有支链氨基酸，可以影响动物的昼夜节律和行为。
T8638	NPC 15199 FMOC-L-Leucine,Fmoc-L-亮氨酸	Others	Others
	NPC 15199 (FMOC-L-Leucine) 是选择性的PPARγ调节剂。它对 PPARγ 的激活效果比罗格列酮低，但二者最大效应相似。它能够改善正常、饮食诱导的葡萄糖不耐受和糖尿病 db/db 小鼠的胰岛素敏感性，一定程度上能够诱导脂肪生成。
TP1367L	[D-Ala2]leucine-enkephalin acetate [D-Ala2]leucine-enkephalin acetate(64963-01-5 free base)	Opioid Receptor	Endocrinology/Hormones; GPCR/G Protein; Neuroscience
	[D-Ala2]leucine-enkephalin acetate ([D-Ala2]leucine-enkephalin acetate (64963-01-5 free base)) 是一种 delta 阿片受体激动剂，用于研究 delta 阿片受体的信号通路。
T20433	Leucyl-leucyl-leucine Trileucine
	Leucyl-leucyl-leucine is may be used for pH-dependent endosomal membrane disruption to release agents. Trileucine is used to evaluate the absorption characteristics of reversed phase liquid chromatography (HPLC) media.
T33612	N-Carbomethoxy-L-leucine
	N-Carbomethoxy-L-leucine is a bioactive chemical.
T31967	Glycyl-alanyl-leucine Gly-ala-leu
	Glycyl-alanyl-leucine is a peptide.
T20445	L-Leucine-p-nitroanilide
	L-Leucine-p-nitroanilide is a substrate. It is used for the colorimetric determination of leucine aminopeptidase.
T31854	Formylmethionyl-alanyl-leucine Fmet-ala-leu
	Formylmethionyl-alanyl-leucine is formed by E coli ribosomal protein L10 gene.
T32664	Leucine sarcolysine NSC 167780,NSC-167780,Asaley,NSC167780,Asalex
	Leucine sarcolysine is a bioactive chemical.
T7173	[Leu5]-Enkephalin 亮氨酸脑啡肽,Leucine enkephalin,Leucyl-enkephalin,Leu-enkephalin	Opioid Receptor; Endogenous Metabolite	Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience
	[Leu5]-Enkephalin (Leu-enkephalin) 是一种参与伤害感受的内源性神经肽，是 δ-阿片和 μ-阿片受体的激动剂，Ki 值分别为 4.0 和 3.4 nM
T34622	Seryl-lysyl-leucine Skl tripeptide,Ser-lys-leu
	Seryl-lysyl-leucine is a bioactive chemical.
T7665	[Leu5]-Enkephalin TFA(58822-25-6(free bas)) Leu-enkephalin,Leucine enkephalin,Leucyl-enkephalin	Opioid Receptor; Endogenous Metabolite	Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience
	[Leu5]-Enkephalin TFA(58822-25-6(free bas)) (Leucyl-enkephalin) 是最有效的 δ 受体。
T33087	Lysyl-aspartyl-glutamyl-leucine Kdel sequence,Lys-asp-glu-leu
	Lysyl-aspartyl-glutamyl-leucine maintains type II surface membrane proteins in the endoplasmic reticulum.
T36879	L-Leucyl-L-Leucine methyl ester hydrobromide
	The lysosomotropic dipeptide LLME has selective toxicity for NK cells, CTL, and M phi without adverse effects on a variety of other lymphoid or nonlymphoid cell types. See also E-2080.
T32082	Histidyl-aspartyl-glutamyl-leucine His-asp-glu-leu,Hdel sequence
	HDEL intracellular distribution is characteristic of plant endoplasmic reticulum (ER).
T31907	Gamma-Methylleucine L-Neopentylglycine,gamma-Methyl-L-leucine,3-叔丁基-L-丙氨酸,2-Amino-3-tert-butylpropionic acid	Others	Others
	Gamma-Methylleucine (2-Amino-3-tert-butylpropionic acid) 是铜催化的不对称迈克尔反应的辅助剂。
T37062	L-Leucine-7-amido-4-methylcoumarin hydrochloride
	L-Leu-AMC is a fluorogenic substrate for leucine aminopeptidase.1Upon enzymatic cleavage by leucine aminopeptidase, AMC is released and its fluorescence can be used to quantify leucine aminopeptidase activity. AMC displays excitation/emission maxima of 340-360/440-460 nm, respectively. 1.Izquierdo, M., Lin, D., O’Neill, S., et al.Development of a high-throughput screening assay to identify inhibitors of the major M17-leucyl aminopeptidase from Trypanosoma cruzi using rapidfire mass spectrometryS...
T7173L	[Leu5]-Enkephalin acetate(58822-25-6 free base) 亮氨酸脑啡肽,Leucine enkephalin,Leu-enkephalin,Leucyl-enkephalin	Opioid Receptor; Endogenous Metabolite	Endocrinology/Hormones; GPCR/G Protein; Metabolism; Neuroscience
	[Leu5]-Enkephalin acetate(58822-25-6 free base) 是一种参与伤害感受的内源性神经肽，是 δ-opioid 和 μ-opioid 受体的激动剂(Kis 分别为 4.0 和 3.4 nM)
T39972	EB-42486	LRRK2	Autophagy
	EB-42486 是一种有效且高度选择性的 G2019S-LRRK2 抑制剂，IC50 < 0.2 nM。
T2050	PF-06447475	LRRK2	Autophagy
	PF-06447475是一种高效、特异性的脑渗透性 LRRK2 抑制剂，IC50值为3 nM。
T16115	MLi-2	LRRK2	Autophagy
	MLi-2 是一种结构新颖、高效、选择性的 LRRK2 激酶抑制剂，具有中枢神经系统活性，IC50为 0.76 nM，有潜力用于帕金森氏病。
T1945	GNE-7915 GNE7915	LRRK2	Autophagy
	GNE-7915是一种高效选择性，可渗透大脑的，富含亮氨酸的重复激酶 2 (LRRK2) 抑制剂，IC50值为9 nM。
T11996	MELK-8a hydrochloride	MELK	PI3K/Akt/mTOR signaling
	MELK-8a hydrochloride 是一种有效的母体胚胎亮氨酸拉链激酶抑制剂，IC50 为 2 nM。
T76108	Leucine dehydrogenase
	Leucine dehydrogenase 能够从球形芽孢杆菌中纯化得到。Leucine dehydrogenase 催化L-亮氨酸、L-缬氨酸、L-异亮氨酸、L-去甲缬氨酸、左旋α-氨基丁酸酯和L-去甲亮氨酸的氧化脱氨，以及它们的酮类似物的还原胺化。
T7729	PF-06454589	LRRK2	Autophagy
	PF-06447475 是LRRK2激酶选择性抑制剂，可通透血脑屏障，能够抑制 WT LRRK (IC50:3 nM) 和 G2019S LRRK2 (IC50:11 nM) 。它可用于研究帕金森病 (PD) 。
T20426	Dansylleucine Dns-leucine,Dansyl-leucine
	Dansylleucine is an agent of bioactive chemical.
T2022	CZC-54252 CZC54252,CZC 54252	LRRK2	Autophagy
	CZC-54252 是一种选择性 LRRK2有效抑制剂，对野生型和 G2019S LRRK2的 IC50分别为 1.28 nM 和 1.85 nM。它具有神经保护活性，可减弱由 G2019S LRRK2 诱导的人神经元损伤，EC50约为 1 nM。
T31948	Glutarylleucine Glutaryl-L-leucine
	Glutarylleucine is a bioactive chemical.
T64647	Boc-L-Leucine
	Boc-L-Leucine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64647，CAS号为 13139-15-6。
T1770	GNE-9605	LRRK2	Autophagy
	GNE-9605 是一个高效，选择性和能脑渗透的LRRK2抑制剂，IC50为19 nM。
T7155	JH-II-127	LRRK2	Autophagy
	JH-II-127是一种高选择性的脑渗透性 LRRK2 抑制剂，抑制野生型 LRRK2、G2019S LRRK2和 A2016T LRRK2，IC50 值分别为6.6 nM、2.2 nM 和 47.7 nM。
T8985	NSC45586	Others	Others
	NSC45586 是一种蛋白磷酸酶 PHLPP 抑制剂，对 PHLPP1 和 PHLPP2 具有选择性。
T66098	N-Benzyloxycarbonyl-tert-leucine
	N-Benzyloxycarbonyl-tert-leucine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66098，CAS号为 62965-10-0。
T6031	GNE0877 GNE 0877,GNE-0877	LRRK2	Autophagy
	GNE0877 (GNE 0877) 是一种高效且特异性的富含亮氨酸的重复激酶 2(LRRK2) 抑制剂，IC50为3 nM，Ki 为0.7 nM
T3053	CZC-25146 CHEMBL2397014	LRRK2	Autophagy
	CZC-25146 (CHEMBL2397014) 是一种有效、特异性和代谢稳定的 LRRK2 抑制剂，对野生型 LRRK2 和 G2019S LRRK2 的 IC50 分别为 4.76 和 6.87 nM。
T3707	GNE-3511 GNE3511	DNA Alkylation; MAPK	DNA Damage/DNA Repair; MAPK
	GNE-3511是双亮氨酸拉链激酶 (DLK)抑制剂(Ki:0.5 nM)。
T16512	PFE-360 PF-06685360	LRRK2	Autophagy
	PFE-360 (PF-06685360) 是一种有效的选择性 LRRK2 激酶抑制剂，在体内的 IC50值为 2.3 nM。
T131571	N-Benzoyl-L-Leucine
	N-Benzoyl-L-Leucine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131571。
T34020	Phenylalanylleucine Phe-leu,L-Phenylalanyl-L-leucine
	Phenylalanylleucine is a bioactive chemical.
T33574	N-Acetylmelphalanylleucine N-Acetyl-melphalan-L-leucine
	N-Acetylmelphalanylleucine is a bioactive chemical.
T20443	Tyrosylleucine Tyr-leu,L-Tyrosyl-L-leucine
	Tyrosylleucine is a dipeptide composed of tyrosine and leucine. Some dipeptides are known to have physiological or cell-signaling effects although most are simply short-lived intermediates on their way to specific amino acid degradation pathways following
T5139	CZC-25146 hydrochloride	LRRK2	Autophagy
	CZC-25146 hydrochloride 是一种有效、特异性和代谢稳定的 LRRK2 抑制剂，对野生型 LRRK2 和 G2019S LRRK2 的 IC50 分别为 4.76 和 6.87 nM。
T31711L	Ethyl L-leucinate Leucine ethyl ester
	Ethyl L-leucinate is a essential amino acid.

化合物

N-Cbz-L-Leucine

Cat.No: T64400

Synonym: N-[(Phenylmethoxy)carbonyl]-L-leucine

Target: Amino Acids and Derivatives

L-Leucine-1-13C

Cat.No: T32811

Synonym: L-(1-13C)Leucine,(1-13C)Leucine

Target: Endogenous Metabolite, mTOR

[D-Ala2]leucine-enkephalin

Cat.No: TP1367

Synonym: (D-ALA2)-亮氨酸脑啡肽

Target: Opioid Receptor

N-Oleoyl Leucine

Cat.No: T35785

L-Leucyl-L-Leucine methyl ester hydrochloride

Cat.No: T7739

Synonym: Leu-Leu-ome hydrochloride

Target: Others, Endogenous Metabolite

Cat.No: T1387

Synonym: N-Acetyl-DL-leucine,乙酰亮氨酸,N-acetyl-L-leucine

Target: Amino Acids and Derivatives

Leucine thiorphan

Cat.No: T25676

Synonym: Leu-thiorphan

Cat.No: TP1264

Synonym: ((Benzyloxy)carbonyl)-L-prolyl-D-leucine

Target: Others

Cat.No: T8638

Synonym: FMOC-L-Leucine,Fmoc-L-亮氨酸

Target: Others

[D-Ala2]leucine-enkephalin acetate

Cat.No: TP1367L

Synonym: [D-Ala2]leucine-enkephalin acetate(64963-01-5 free base)

Target: Opioid Receptor

Leucyl-leucyl-leucine

Cat.No: T20433

Synonym: Trileucine

N-Carbomethoxy-L-leucine

Cat.No: T33612

Glycyl-alanyl-leucine

Cat.No: T31967

Synonym: Gly-ala-leu

L-Leucine-p-nitroanilide

Cat.No: T20445

Formylmethionyl-alanyl-leucine

Cat.No: T31854

Synonym: Fmet-ala-leu

Leucine sarcolysine

Cat.No: T32664

Synonym: NSC 167780,NSC-167780,Asaley,NSC167780,Asalex

[Leu5]-Enkephalin

Cat.No: T7173

Synonym: 亮氨酸脑啡肽,Leucine enkephalin,Leucyl-enkephalin,Leu-enkephalin

Target: Opioid Receptor, Endogenous Metabolite

Seryl-lysyl-leucine

Cat.No: T34622

Synonym: Skl tripeptide,Ser-lys-leu

[Leu5]-Enkephalin TFA(58822-25-6(free bas))

Cat.No: T7665

Synonym: Leu-enkephalin,Leucine enkephalin,Leucyl-enkephalin

Target: Opioid Receptor, Endogenous Metabolite

Lysyl-aspartyl-glutamyl-leucine

Cat.No: T33087

Synonym: Kdel sequence,Lys-asp-glu-leu

L-Leucyl-L-Leucine methyl ester hydrobromide

Cat.No: T36879

Histidyl-aspartyl-glutamyl-leucine

Cat.No: T32082

Synonym: His-asp-glu-leu,Hdel sequence

Gamma-Methylleucine

Cat.No: T31907

Synonym: L-Neopentylglycine,gamma-Methyl-L-leucine,3-叔丁基-L-丙氨酸,2-Amino-3-tert-butylpropionic acid

Target: Others

L-Leucine-7-amido-4-methylcoumarin hydrochloride

Cat.No: T37062

[Leu5]-Enkephalin acetate(58822-25-6 free base)

Cat.No: T7173L

Synonym: 亮氨酸脑啡肽,Leucine enkephalin,Leu-enkephalin,Leucyl-enkephalin

Target: Opioid Receptor, Endogenous Metabolite

Cat.No: T39972

Target: LRRK2

Cat.No: T2050

Target: LRRK2

Cat.No: T16115

Target: LRRK2

Cat.No: T1945

Synonym: GNE7915

Target: LRRK2

MELK-8a hydrochloride

Cat.No: T11996

Target: MELK

Leucine dehydrogenase

Cat.No: T76108

Cat.No: T7729

Target: LRRK2

Cat.No: T20426

Synonym: Dns-leucine,Dansyl-leucine

Cat.No: T2022

Synonym: CZC54252,CZC 54252

Target: LRRK2

Glutarylleucine

Cat.No: T31948

Synonym: Glutaryl-L-leucine

Boc-L-Leucine

Cat.No: T64647

Cat.No: T1770

Target: LRRK2

Cat.No: T7155

Target: LRRK2

Cat.No: T8985

Target: Others

N-Benzyloxycarbonyl-tert-leucine

Cat.No: T66098

Cat.No: T6031

Synonym: GNE 0877,GNE-0877

Target: LRRK2

Cat.No: T3053

Synonym: CHEMBL2397014

Target: LRRK2

Cat.No: T3707

Synonym: GNE3511

Target: DNA Alkylation, MAPK

Cat.No: T16512

Synonym: PF-06685360

Target: LRRK2

N-Benzoyl-L-Leucine

Cat.No: T131571

Phenylalanylleucine

Cat.No: T34020

Synonym: Phe-leu,L-Phenylalanyl-L-leucine

N-Acetylmelphalanylleucine

Cat.No: T33574

Synonym: N-Acetyl-melphalan-L-leucine

Cat.No: T20443

Synonym: Tyr-leu,L-Tyrosyl-L-leucine

CZC-25146 hydrochloride

Cat.No: T5139

Target: LRRK2

Ethyl L-leucinate

Cat.No: T31711L

Synonym: Leucine ethyl ester

Cat. No.	Product Name	Target	Signaling Pathways
T4772	(±)-Leucine DL-Leucine,(+/-)-Amino-4-methylpentanoic acid,DL-亮氨酸,DL-2-Aminmo-4-methylvalerianic acid	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	(±)-Leucine (DL-2-Aminmo-4-methylvalerianic acid) 是亮氨酸的异构体，是一种化学杀菌剂和膳食添加剂，存在于青椒、青西葫芦、意大利甜红辣椒和红甜椒中。
T9299	D-Leucine D-亮氨酸,(R)-Leucine	Endogenous Metabolite	Metabolism
	D-Leucine ((R)-Leucine) 具有抗癫痫特性，活性比L-leucine，能够有效终止癫痫发作。在体外，它能够抑制长期点位，但基底突触传递无影响。
T3O2749	L-Leucine (S)-Leucine,Leu,L-亮氨酸,亮氨酸	mTOR	PI3K/Akt/mTOR signaling
	L-Leucine ((S)-Leucine) 是必需的支链氨基酸，能够激活 mTOR 信号通路。
T4798	N-Acetyl-L-leucine	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-L-leucine 是内源性代谢产物的一种。
T4086	Glycyl-L-leucine 甘氨酰-L-亮氨酸,Gly-Leu	Others	Others
	Glycyl-L-leucine (Gly-Leu) 是一种可用作糖基亮氨酸二肽酶底物的二肽。
T8373	6-Diazo-5-oxo-L-nor-Leucine DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine	Influenza Virus; Glutaminase; Antibacterial; Antibiotic	Microbiology/Virology; Proteases/Proteasome
	6-Diazo-5-oxo-L-nor-Leucine (L-6-Diazo-5-oxonorleucine) 是一种谷氨酰胺拮抗剂，具有抗菌、抗病毒和抗癌作用，其Ki 值为 6 μM。它能降低肿瘤细胞的自我更新能力和转移能力，在体外表现出遗传毒性。
T5569	3-Amino-4-methylpentanoic acid DL-Homovaline,3-氨基-4-甲基戊酸,DL-beta-leucine,beta-Aminoisocaproic acid,beta-Leucine	Endogenous Metabolite	Metabolism
	3-Amino-4-methylpentanoic acid (DL-Homovaline) 是 L-亮氨酸的异构体，是 β 氨基酸，通过亮氨酸 2,3-氨基变位酶在人体中由 L-亮氨酸代谢天然产生。
TMA2613	Cyclo(Pro-Leu) Cyclo-L-leu-L-pro,Cyclo-L-prolyl-L-leucine,Cyclo(leucyloprolyl)	Others	Others
	Cyclo(Pro-Leu) (Cyclo-L-prolyl-L-leucine) 是一种源自海洋的天然产物，具有盐水虾的杀伤力。
T4765	L-Norleucine (S)-Norleucine,alpha-Aminocaproic acid,(S)-2-Aminohexanoic acid,L-2-氨基己酸	Influenza Virus; Endogenous Metabolite	Metabolism; Microbiology/Virology
	L-Norleucine ((S)-Norleucine) 是亮氨酸的异构体，特异性影响骨骼肌中的蛋白质合成，具有抗病毒活性。
T0063	L-Isoleucine 异亮氨酸,isoleucine,Ile,L-异亮氨酸	Amino Acids and Derivatives; Endogenous Metabolite	Metabolism
	L-Isoleucine (Ile) 是一种非极性疏水性氨基酸。它是必需氨基酸。
T19384	Isovalerylcarnitine	Apoptosis; Cysteine Protease	Apoptosis; Proteases/Proteasome
	Isovalerylcarnitine (3-methylbutyrylcarnitine) 是 L-亮氨酸分解代谢和异戊酸的积累产生的小分子化合物，也是一种具有选择性和有效性的钙蛋白酶 (calpain) 激活剂，可促使细胞凋亡，与异戊酸血症有关，可作为异戊酸血症的标志。
T4766	3-Methylglutaric acid	Endogenous Metabolite	Metabolism
	3-Methylglutaric acid 是亮氨酸代谢物，是一种与两种亮氨酸途径 HMGCL、AUH 酶缺陷显著相关的 C6 二元羧酸有机酸。
T5294	(S)-Leucic acid L-alpha-羟基异己酸,L-LEUCIC ACID,Hydroxyisocaproic acid,(S)-2-羟基-4-甲基戊酸,(S)-(−)-2-Hydroxyisocaproic acid	Others; Endogenous Metabolite	Metabolism; Others
	(S)-Leucic acid (Hydroxyisocaproic acid) 是氨基酸代谢物。
T1257	Bestatin Ubenimex,乌苯美司	Others; Aminopeptidase; Antibacterial; Antibiotic; LTR	Immunology/Inflammation; Metabolism; Microbiology/Virology; Others
	Bestatin (Ubenimex) 是 CD13 (Aminopeptidase N)/APN 和 leukotriene A4 hydrolase 抑制剂，可用于癌症研究。
T5245	N-Isovaleroylglycine N-异戊酰氨基乙酸,Isovaleroylglycine,N-Isovalerylglycine	Others; Endogenous Metabolite	Metabolism; Others
	N-Isovaleroylglycine (Isovaleroylglycine) 是酰基甘氨酸，能够作为体重提高和肥胖的生物标记物。
T11203	Enocyanin	Others	Others
	Enocyanin, an anthocyanin extracted from grapes, exhibits inhibitory effects on leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase, and esterase activity.
TN2408	Evofolin B	Cannabinoid Receptor	GPCR/G Protein
	Evofolin B 是从Zanthoxylum ailanthoides 的茎皮中分离出来的天然化合物。Evofolin B 对人类中性粒细胞对甲酰-L-蛋氨酸-L-亮氨酸-L-苯丙氨酸/cytochalasin B（fMLP/CB）产生的超氧阴离子有抑制作用。
T14121	Actinonin (-)-Actinonin	Aminopeptidase	Metabolism
	Actinonin ((-)-Actinonin) is a naturally occurring antibacterial agent produced by Actinomyces and a potent reversible peptide deformylase (PDF) inhibitor with a Ki of 0.28 nM, it also is an apoptosis inducer. Actinonin inhibits aminopeptidase M, aminopeptidase N and leucine aminopeptidase, it also inhibits MMP-1, MMP-3, MMP-8, MMP-9, and hmeprin α with Ki values of 300 nM, 1,700 nM, 190 nM, 330 nM, and 20 nM, respectively. Actinonin has antiproliferative and antitumor activities[1][2][3][4][5].

天然产物

Cat.No: T4772

Synonym: DL-Leucine,(+/-)-Amino-4-methylpentanoic acid,DL-亮氨酸,DL-2-Aminmo-4-methylvalerianic acid

Target: Others, Endogenous Metabolite, Antibacterial

Cat.No: T9299

Synonym: D-亮氨酸,(R)-Leucine

Target: Endogenous Metabolite

Cat.No: T3O2749

Synonym: (S)-Leucine,Leu,L-亮氨酸,亮氨酸

Target: mTOR

N-Acetyl-L-leucine

Cat.No: T4798

Target: Others, Endogenous Metabolite

Glycyl-L-leucine

Cat.No: T4086

Synonym: 甘氨酰-L-亮氨酸,Gly-Leu

Target: Others

6-Diazo-5-oxo-L-nor-Leucine

Cat.No: T8373

Synonym: DON,L-6-Diazo-5-oxonorleucine,6-重氮-5-氧代-L-正亮氨酸,Diazooxonorleucine

Target: Influenza Virus, Glutaminase, Antibacterial, Antibiotic

3-Amino-4-methylpentanoic acid

Cat.No: T5569

Synonym: DL-Homovaline,3-氨基-4-甲基戊酸,DL-beta-leucine,beta-Aminoisocaproic acid,beta-Leucine

Target: Endogenous Metabolite

Cat.No: TMA2613

Synonym: Cyclo-L-leu-L-pro,Cyclo-L-prolyl-L-leucine,Cyclo(leucyloprolyl)

Target: Others

Cat.No: T4765

Synonym: (S)-Norleucine,alpha-Aminocaproic acid,(S)-2-Aminohexanoic acid,L-2-氨基己酸

Target: Influenza Virus, Endogenous Metabolite

Cat.No: T0063

Synonym: 异亮氨酸,isoleucine,Ile,L-异亮氨酸

Target: Amino Acids and Derivatives, Endogenous Metabolite

Isovalerylcarnitine

Cat.No: T19384

Target: Apoptosis, Cysteine Protease

3-Methylglutaric acid

Cat.No: T4766

Target: Endogenous Metabolite

(S)-Leucic acid

Cat.No: T5294

Synonym: L-alpha-羟基异己酸,L-LEUCIC ACID,Hydroxyisocaproic acid,(S)-2-羟基-4-甲基戊酸,(S)-(−)-2-Hydroxyisocaproic acid

Target: Others, Endogenous Metabolite

Cat.No: T1257

Synonym: Ubenimex,乌苯美司

Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR

N-Isovaleroylglycine

Cat.No: T5245

Synonym: N-异戊酰氨基乙酸,Isovaleroylglycine,N-Isovalerylglycine

Target: Others, Endogenous Metabolite

Cat.No: T11203

Target: Others

Cat.No: TN2408

Target: Cannabinoid Receptor

Cat.No: T14121

Synonym: (-)-Actinonin

Target: Aminopeptidase

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