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49

抑制剂 & 化合物

9

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Cat. No. Product Name Target Signaling Pathways
T0347 Phenol Red

Sulfonphthal,Sulphental,酚红,Fenolipuna

Others Others
Phenol Red (Sulfonphthal) 是一种pH 指示染料,当出现阳性反应时,会发生由粉红色到黄色的明显颜色变化。
T5426 DMNQ

Reactive Oxygen Species; ROS Immunology/Inflammation; Metabolism; NF-κB
DMNQ 是氧化还原循环剂,以浓度依赖性方式在细胞内产生超氧化物和过氧化氢,能够诱导ROS 增加。
T7109 TMB-PS

TMBZ-PS

Others Others
TMB-PS (TMBZ-PS) 是 N-(3-sulfopropyl)-3,3',5,5'-tetramenthylbenzidine sodium salt,具有水溶性,可适应各种 ph 环境。
T3572 NSC 15364

1,3-Bis(4-aminophenyl)urea,NSC15364

Apoptosis; Others; VDAC Apoptosis; Membrane transporter/Ion channel; Others
NSC 15364 (1,3-Bis(4-aminophenyl)urea) 是一种 VDAC1寡聚化和细胞凋亡抑制剂。
T0404 8-Hydroxyquinoline

Hydroxyquinoline,8-Quinolinol,羟基喹啉,Oxine,8-羟基喹啉,8-Oxychinolin

Others; Antibacterial; Antibiotic Microbiology/Virology; Others
8-Hydroxyquinoline (8-Quinolinol) 是单质子二齿螯合剂, 也是转录抑制剂,防腐剂,消毒剂和杀虫剂。
T21233 Dihydrolipoic acid

Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid,二氢硫辛酸

Antioxidant oxidation-reduction
Dihydrolipoic acid (USAF XR-12) 是高效的抗氧化剂,对所有以氧为中心的自由基都有很强的清除能力。它在多种疾病中表现出抗炎特性。在 LPS 诱导的疾病行为大鼠中,它通过 ERK/Nrf2/HO-1/ROS/NLRP3 通路发挥预防作用。它还可以可用于抑郁症的研究。
T8321 10-methyl-9-(phenoxycarbonyl) Acridinium

Others Others
10-methyl-9-(phenoxycarbonyl) Acridinium 是一种吖啶鎓酯,在碱性条件下与过氧化氢、过硫酸盐和其他氧化剂氧化后会产生荧光 10-methyl-9-acridone。
T5983 o-Phenanthroline

1,10-菲罗啉,1,10-Phenanthroline

MMP; Others Others; Proteases/Proteasome
o-Phenanthroline (1,10-Phenanthroline) 是一种金属螯合剂,能够与 Fe2+形成红色螯合物,在 510 nm 处最大吸收,可防止链脲佐菌素诱导染色体畸变。它也是一种MMP 的抑制剂。
T11064 DMT1 blocker 2

Others Others
DMT1 blocker 2 是一种二价金属转运蛋白 1 的直接抑制剂(IC50:0.83 μM)。它可以阻断体内肠细胞的铁摄取。
T33412 MitoPQ

MitoParaquat

Glucokinase; transporter Metabolism
MitoPQ (MitoParaquat) 是一个线粒体靶向的小分子化合物。MitoPQ 选择性加强线粒体超氧化物和过氧化氢的含量,抑制胰岛素刺激的葡萄糖摄取和葡萄糖转运蛋白 4 (GLUT4) 向脂肪细胞和肌管中质膜的易位。MitoPQ 可用于研究线粒体氧化应激与调节的 GLUT4 转运。
T38003 Levofloxacin N-oxide

Others Others
Levofloxacin N-oxide 是从左氧氟沙星中分离出来的杂质。
T35689 MTP 131 acetate

Others Others
MTP 131 acetate 是一种小的线粒体靶向四肽。
T33403 MitoB

MitoB is a novel exon of mitochondrial hydrogen peroxide.
T23135 Peroxy Orange 1

Others Others
fluorescent probe for imaging hydrogen peroxide (H2O2)
T22982 MitoPY1

Others Others
a fluorescent probe for imaging hydrogen peroxide (H2O2) in mitochondria of living cells
T19042 NucPE1

Nuclear Peroxy Emerald 1

Others Others
NucPE1, a nuclear-localized fluorescent hydrogen peroxide, is specifically localized to cellular nuclei without appended targeting moieties.
T39763 Rucosopasem manganese

GC4711

Rucosopasem manganese (GC4711) is a potent, selective superoxide dismutase (SOD) mimetic capable of efficiently converting superoxide to hydrogen peroxide. This compound, specifically designed for research purposes, holds promise in cancer-related studies.
T71288 Phenylbutazone-d9

Phenylbutazone-d9 is intended for use as an internal standard for the quantification of phenylbutazone by GC- or LC-MS. Phenylbutazone is a non-steroidal anti-inflammatory drug and an inhibitor of the peroxidase activity of COX (IC50 = ~100 µM in the presence of hydrogen peroxide). It also inhibits prostaglandin I synthase (IC50 = ~25 µM in the presence of hydrogen peroxide). Phenylbutazone (2 mg/kg) reduces increases in type II collagen levels in the inflamed joints of an equine model of LPS-in...
T36610 (E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine

(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine (CSTMP) is a stilbene derivative with antioxidant and anticancer activities. It stimulates proliferation of hydrogen peroxide-damaged ECV-304 cells (EC50 = 24.9 nM). CSTMP reduces hydrogen peroxide-induced release of lactate dehydrogenase (LDH) in and increases viability of human umbilical vein endothelial cells (HUVECs) in a concentration-dependent manner via inhibition of apoptosis. It reverses hydrogen peroxide-induced release of malondialdehyde ...
T71026 MC2050 HCl

MC2050 is a potent PARP-1 inhibitor. The IC50 for inhibition of PARP-1 activity is 119 nM, compared to 1.8 μM for PARP-2. MC2050 inhibits apoptosis and blocks poly ADP-ribosylation of histone H1 in hydrogen peroxide treated SH-SY5Y neuroblastoma cells.
T38165 FBBBE

FBBBE is a derivatized fluorescein compound that is used to detect the production hydrogen peroxide (H2O2) by cells. Intracellular H2O2, but not extracellular H2O2, initiates the conversion of FBBBE to fluorescein, resulting in an increase in intracellular fluorescence (excitation/emission maxima: 480/512 nm).
T76576 Arg-Tyr

Arg-Tyr 是一种具有强羟自由基和过氧化氢清除活性的二肽。
T38324 Coumarin Boronic Acid

Coumarin boronic acid (CBA) is a fluorescent probe that can be used to detect peroxynitrite , hypochlorous acid, and hydrogen peroxide.It reacts with peroxynitrite at an exponentially faster rate (k = 1.1 μM/s) than hydrogen peroxide (k =1.5 M/s) and moderately faster rate than hypochlorous acid. Peroxynitrite oxidizes CBA into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively.
T78348 Lactate oxidase

Lactate oxidase是一种FMN依赖性酶,能催化乳酸转化为丙酮酸并同时释放过氧化氢,常用于乳酸的检测。
T38325 Coumarin Boronic Acid pinacolate ester

Coumarin boronic acid pinacolate ester (CBE) is a more soluble form of coumarin boronic acid that can be used to detect peroxynitrite , hypochlorous acid, and hydrogen peroxide. Peroxynitrite oxidizes CBE into the fluorescent product 7-hydroxycoumarin (COH), which displays excitation/emission maxima of 332/470 nm, respectively.
T36498 CAY10762

CAY10762

CAY10762 is an inhibitor of monoacylglycerol lipase (MAGL; IC50= 34.1 nM).1It reduces hydrogen peroxide-induced lactate dehydrogenase (LDH) release from Neuro2a cells when used at a concentration of 1 μM. CAY10762 (10 mg/kg) increases levels of 2-arachidonoyl glycerol in mouse brain. 1.Castelli, R., Scalvini, L., Vacondio, F., et al.Benzisothiazolinone derivatives as potent allosteric monoacylglycerol lipase inhibitors that functionally mimic sulfenylation of regulatory cysteinesJ. Med. Chem.63(...
T77263 10-Methyl-9-(phenoxycarbonyl)acridinium (fluorosulfonate)

10-Methyl-9-(phenoxycarbonyl)acridinium fluorosulfonate 为一种吖啶酯类的苯基酯,此化合物作为在中性条件下能产生化学发光的荧光染料,应用于过氧化氢的测定。
T76150 Galactose oxidase

Galactose oxidase (GOase) 半乳糖氧化酶来自真菌,常用于生化研究。Galactose oxidase 是一种 II 型铜金属酶,含有单一多肽。Galactose oxidase 催化伯醇的双电子氧化生成相应的醛,并将二氧还原为过氧化氢。
T67498 3-Amino-1,2,4-triazole

Amitrole,3-AT,1H-1,2,4-Triazol-5-amine,Trapidil impurity B

Reactive Oxygen Species Immunology/Inflammation; Metabolism; NF-κB
3-Amino-1,2,4-triazole (Trapidil impurity B) 是一种过氧化氢酶抑制剂,能够诱导过氧化氢解毒的补偿机制。 该机制涉及增加谷胱甘肽过氧化物酶和谷胱甘肽还原酶的活性。
T38099 APF

APF is an aromatic amino-fluorescein derivative and fluorescent probe for highly reactive radicals. It has low intrinsic fluorescence, however, upon oxidation by hydroxyl radical, hypochlorite ion, and certain peroxidase intermediates, it is converted to the highly fluorescent molecule fluorescein, facilitating the detection of highly reactive biological radicals. APF is not oxidized by nitric oxide (NO), hydrogen peroxide (H2O2), or other oxidants. Fluorescein displays excitation/emission maxim...
T38071 HPF

The biology of highly reactive oxygen radical species is of great interest in many biomedical research disciplines, including neurodegeneration, aging, cancer, and infectious diseases.[1] There are a number of fluorescent reagents, such as 2,7-dichlorodihydrofluorescein (DCDHF), that can be used to detect free radicals, but they have significant limitations due to their facile oxidation by light and numerous non-radical oxidants such as hydrogen peroxide (H2O2). [2] HPF is a cell-permeable aroma...
T35976 6-Formylpterin

Xanthine oxidase (XO) generates reactive oxygen species, including hydrogen peroxide (H2O2), as it oxidizes specific substrates in the presence of water and oxygen. 6-Formylpterin is an oxidized pterin produced by photolytic breakdown of folic acid. It binds to one of two active sites on XO nearly quantitatively and irreversibly and prevents the metabolism of other substrates at the second site, resulting in hetero-substrate" inhibition at nanomolar concentrations. However
T75422 Monoamine oxidase

Monoamine oxidase 是一种由不同多肽组成的酶。Monoamine oxidase 通过产生过氧化氢催化大脑和外周组织中多种生物胺氧化脱氨。Monoamine oxidase 在维持突触神经传递、情绪行为和其他大脑功能的调节中发挥重要作用。
T80056 Glutathione Peroxidase

GSH-Px,EC 1.11.1.9

Glutathione Peroxidase Metabolism
Glutathione Peroxidase (GSH-Px; EC 1.11.1.9),是一种关键的抗氧化酶,能催化GSH与过氧化氢或脂质过氧化物反应,生成GSSG和H2O,从而减缓氧化应激。此酶在生化研究中具有重要应用。
T83357 3-Hydroxy-2-(palmitoyloxy)propyl stearat

3-Hydroxy-2-(palmitoyloxy)propyl stearate是一种从棕色巨藻Fucus virsoides J. Agardh的极性较小部分分离得到的非挥发性化合物。该化合物具有良好的自由基清除能力,并能保护斑马鱼胚胎免受过氧化氢诱导的氧化应激。
T82052 IR-990

IR-990是NIR-II型可激活荧光探针,拥有受体-π-受体(A-π-A)骨架,能实时体内检测H2O2。该化合物还可用于诊断由活性分子导致的药物性肝损伤(DILI)。
T78690 MAO-B-IN-18

Monoamine Oxidase Neuroscience
MAO-B-IN-18是高效的选择性MAO-B抑制剂,其IC50值针对hMAO-B为52 nM,对hMAO-A则为14 μM。此外,MAO-B-IN-18能显著保护神经母细胞瘤和星形胶质细胞培养物免受过氧化氢损伤。
T79251 AChE-IN-30

AChE-IN-30,一种AChE抑制剂,其IC50为4.4 μM。该化合物显示出神经保护活性,能抑制H2O2诱导的细胞凋亡(apoptosis),其机制是通过阻止细胞内ROS的积累。AChE-IN-30适用于阿尔茨海默病的相关研究。
T36501 CYPMPO

RR 071

CYPMPO is a free radical spin trap with excellent trapping capabilities toward hydroxyl and superoxide radicals in biological and chemical systems. Decay of the superoxide adduct of CYPMPO proceeds in an apparent first order fashion with half-lives of 15 and 51 minutes in a UV-illuminated hydrogen peroxide solution and a hypoxanthine/xanthine oxidase system, respectively. CYPMPO traps superoxide radicals generated by bovine neutrophils as effectively as DEPMPO.[1] The high melting point (126°C),...
T78346 Superoxide dismutase

SOD

超氧化物歧化酶(SOD)是能清除超氧阴离子的抗氧化酶,它将自由基转化为氧气和过氧化氢,防止过氧亚硝酸盐的形成和进一步损伤。该酶在抗炎、抗肿瘤、辐射防护及抗衰老领域有着广泛应用和研究。
T37270 9(E),11(E)-12-nitro Conjugated Linoleic Acid

9(E),11(E)-12-nitro Conjugated linoleic acid (9(E),11(E)-12-nitro CLA) is a nitrated fatty acid. It is formed from 9(Z),11(E)-CLA upon exposure to acidified nitrite, peroxynitrite, gaseous nitrogen dioxide, or a combination of myeloperoxidase, hydrogen peroxide, and nitrite.1It is also formed in LPS-stimulated RAW 264.7 macrophages, an effect that can be reduced by the nitric oxide synthase (NOS) inhibitor L-NAME .29(E),11(E)-12-nitro CLA has been found in human plasma. 1.Woodcock, S.R., Salvato...
T35966 Mn(III)TMPyP

Mn(III)TMPyP is a manganese-porphyrin which acts as a superoxide dismutase (SOD) mimetic and peroxynitrite decomposition catalyst. SOD mimetics described to date are unstable and are capable of catalyzing undesired side-reactions in addition to the dismutation of the superoxide radical (O2-). Mn(III)TMPyP is an SOD mimetic with increased stability to pH and hydrogen peroxide. The rate constant for superoxide dismutation and peroxynitrite decomposition are 3.9 x 107 M-1s-1 and ~2 x 106 M-1s-1, re...
T83730 Tat-M2NX TFA

Tat-M2NX是一种瞬时受体电位麦拉斯汀2(TRPM2)的肽类拮抗剂。在25到100µM的浓度范围内,能够抑制表达人类TRPM2的HEK293细胞中氢过氧化物诱导的钙离子流入。在体内,Tat-M2NX(20 mg/kg)通过在中大脑动脉阻塞(MCAO)诱导的中风模型中,如果在阻塞前或阻塞后3小时内给药,能减少雄性小鼠的脑梗塞体积,但对雌性小鼠无效。
T71981 Gliclazide-d4

Gliclazide-d4 is intended for use as an internal standard for the quantification of gliclazide by GC- or LC-MS. Gliclazide is a sulfonylurea and an inhibitor of pancreatic β-cell ATP-sensitive potassium (KATP) channels. It is selective for pancreatic β-cell over cardiac and arterial smooth muscle cell KATP channels. Gliclazide (5 μM) increases insulin-induced glucose uptake and glucose transporter 4 (GLUT4) translocation to the plasma membrane in a differentiated 3T3L1 adipocyte model of insulin...
T83875 HUP-55

HUP-55是一种脯氨酸内肽酶的抑制剂(IC50 = 5 nM)。在10 µM的浓度下,它可减少Neuro2a细胞中α-突触核蛋白二聚体的形成,促使HEK293细胞发生自噬,并降低SH-SY5Y细胞中由过氧化氢诱导的反应性氧种(ROS)产量的增加。此外,HUP-55(10 mg/kg)在通过腺病毒递送α-突触核蛋白编码载体(AAV-αSyn)诱导的帕金森病小鼠模型中,能减少患侧爪的使用和纹状体中寡聚体α-突触核蛋白水平。
T35995 Ferrichrome (iron-free)

Ferrichrome (iron-free) 是一种异羟肟酸盐铁载体,可由各种真菌产生(包括 U. sphaerogena),促进这些生物体对铁的螯合和吸收,还被细菌用作异源铁载体,包括铜绿假单胞菌和副溶血性弧菌。 Ferrichrome (iron-free) (0.8 μM) 可以抑制由刀豆球蛋白 A 诱导的小鼠脾脏单核细胞增殖,并减少刀豆球蛋白 A 刺激的 CD4+ T 细胞的数量。它还以浓度依赖性方式抑制过氧化氢对 LDL 的血红素催化氧化。
T83866 LCC-12 formate

LCC-12是一种铜(II)螯合剂,为二甲双胍的衍生物。作为单体,它能结合铜(II)并在20 µM的浓度下减少氢过氧化物依赖的NADH向NAD+的氧化。在10 µM的浓度下,LCC-12降低一次性人类细胞因子激活的单核衍生的巨噬细胞(MDMs)中IL-1β、IL-2、IL-6、IL-8和TNF-α的细胞因子水平,以及JAK2、STAT2和IL-1受体相关激酶4(IRAK4)的水平。此外,同样浓度的LCC-12减少了细胞因子激活的MDMs中CD80+和CD86+的数量。每日0.3 mg/kg的剂量可提高LPS或盲肠结扎穿孔模型小鼠的存活率。
T35983 Carotenoid Mixture

Carotenoid mixture is a mixture of carotenoids that contains the antioxidative and anti-inflammatory carotenoid capsanthin and the antioxidative vitamin A precursor β-carotene , as well as additional carotenoids and carotenoid esters.1,2,3,4 1.Kim, J.S., Lee, W.M., Rhee, H.C., et al.Red paprika (Capsicum annuum L.) and its main carotenoids, capsanthin and β-carotene, prevent hydrogen peroxide-induced inhibition of gap-junction intercellular communicationChem. Biol. Interact.254146-155(2016) 2.Na...
T36176 AMK (hydrochloride)

AMK is an active metabolite of the neurohormone melatonin .1,2,3,4It is formed from melatoninviathe metabolic intermediate AFMK that is then deformylated by catalase or formamidase.5,6AMK scavenges singlet oxygenin vitrowhen used at a concentration of 200 μM.1It inhibits the epinephrine- and arachidonic acid-induced production of prostaglandin E2and PGD2in ovine seminal vesicle microsomes in a concentration- and time-dependent manner, as well as LPS-induced increases in COX-2 levels in RAW 264.7...

化合物

Phenol Red
Cat.No: T0347
Synonym: Sulfonphthal,Sulphental,酚红,Fenolipuna
Target: Others
DMNQ
Cat.No: T5426
Synonym:
Target: Reactive Oxygen Species, ROS
TMB-PS
Cat.No: T7109
Synonym: TMBZ-PS
Target: Others
NSC 15364
Cat.No: T3572
Synonym: 1,3-Bis(4-aminophenyl)urea,NSC15364
Target: Apoptosis, Others, VDAC
8-Hydroxyquinoline
Cat.No: T0404
Synonym: Hydroxyquinoline,8-Quinolinol,羟基喹啉,Oxine,8-羟基喹啉,8-Oxychinolin
Target: Others, Antibacterial, Antibiotic
Dihydrolipoic acid
Cat.No: T21233
Synonym: Reduced thioctic acid,Reduced lipoic acid,DHLA,USAF XR-12,6,8-Dihydrothioctic acid,二氢硫辛酸
Target: Antioxidant
10-methyl-9-(phenoxycarbonyl) Acridinium
Cat.No: T8321
Synonym:
Target: Others
o-Phenanthroline
Cat.No: T5983
Synonym: 1,10-菲罗啉,1,10-Phenanthroline
Target: MMP, Others
DMT1 blocker 2
Cat.No: T11064
Synonym:
Target: Others
MitoPQ
Cat.No: T33412
Synonym: MitoParaquat
Target: Glucokinase, transporter
Levofloxacin N-oxide
Cat.No: T38003
Synonym:
Target: Others
MTP 131 acetate
Cat.No: T35689
Synonym:
Target: Others
MitoB
Cat.No: T33403
Synonym:
Target:
Peroxy Orange 1
Cat.No: T23135
Synonym:
Target: Others
MitoPY1
Cat.No: T22982
Synonym:
Target: Others
NucPE1
Cat.No: T19042
Synonym: Nuclear Peroxy Emerald 1
Target: Others
Rucosopasem manganese
Cat.No: T39763
Synonym: GC4711
Target:
Phenylbutazone-d9
Cat.No: T71288
Synonym:
Target:
(E)-2-(2-Chlorostyryl)-3,5,6-trimethylpyrazine
Cat.No: T36610
Synonym:
Target:
MC2050 HCl
Cat.No: T71026
Synonym:
Target:
FBBBE
Cat.No: T38165
Synonym:
Target:
Arg-Tyr
Cat.No: T76576
Synonym:
Target:
Coumarin Boronic Acid
Cat.No: T38324
Synonym:
Target:
Lactate oxidase
Cat.No: T78348
Synonym:
Target:
Coumarin Boronic Acid pinacolate ester
Cat.No: T38325
Synonym:
Target:
CAY10762
Cat.No: T36498
Synonym: CAY10762
Target:
10-Methyl-9-(phenoxycarbonyl)acridinium (fluorosulfonate)
Cat.No: T77263
Synonym:
Target:
Galactose oxidase
Cat.No: T76150
Synonym:
Target:
3-Amino-1,2,4-triazole
Cat.No: T67498
Synonym: Amitrole,3-AT,1H-1,2,4-Triazol-5-amine,Trapidil impurity B
Target: Reactive Oxygen Species
APF
Cat.No: T38099
Synonym:
Target:
HPF
Cat.No: T38071
Synonym:
Target:
6-Formylpterin
Cat.No: T35976
Synonym:
Target:
Monoamine oxidase
Cat.No: T75422
Synonym:
Target:
Glutathione Peroxidase
Cat.No: T80056
Synonym: GSH-Px,EC 1.11.1.9
Target: Glutathione Peroxidase
3-Hydroxy-2-(palmitoyloxy)propyl stearat
Cat.No: T83357
Synonym:
Target:
IR-990
Cat.No: T82052
Synonym:
Target:
MAO-B-IN-18
Cat.No: T78690
Synonym:
Target: Monoamine Oxidase
AChE-IN-30
Cat.No: T79251
Synonym:
Target:
CYPMPO
Cat.No: T36501
Synonym: RR 071
Target:
Superoxide dismutase
Cat.No: T78346
Synonym: SOD
Target:
9(E),11(E)-12-nitro Conjugated Linoleic Acid
Cat.No: T37270
Synonym:
Target:
Mn(III)TMPyP
Cat.No: T35966
Synonym:
Target:
Tat-M2NX TFA
Cat.No: T83730
Synonym:
Target:
Gliclazide-d4
Cat.No: T71981
Synonym:
Target:
HUP-55
Cat.No: T83875
Synonym:
Target:
Ferrichrome (iron-free)
Cat.No: T35995
Synonym:
Target:
LCC-12 formate
Cat.No: T83866
Synonym:
Target:
Carotenoid Mixture
Cat.No: T35983
Synonym:
Target:
AMK (hydrochloride)
Cat.No: T36176
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T5760 (-​)​-​Salutaridine

清风藤碱,SINOACUTINE

Others Others
(-​)​-​Salutaridine 是一种生物碱。
TN2436 4-methyl-6-phenyl-2H-pyranone

4-methyl-6-phenyl-2H-pyranone

Mitochondrial Metabolism Metabolism
4-methyl-6-phenyl-2H-pyranone 源自黄芩黄芩,可改善线粒体功能以保护星形胶质细胞免受过氧化氢诱导的毒性。
T4904 1-Methylguanidine hydrochloride

Others; Endogenous Metabolite Metabolism; Others
1-Methylguanidine hydrochloride 是内源性代谢产物的一种。
TL0008 Gigantol

Wnt/beta-catenin; Glucosidase Cytoskeletal Signaling; Metabolism; Stem Cells
Gigantol 是一种联苄基化合物,从几种药用兰花中获得,是一种Wnt/β-catenin 通路抑制剂,具有抗肿瘤活性。
T3729 Ethyl gallate

Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯

MMP; NF-κB; Akt; Antibacterial Cytoskeletal Signaling; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling; Proteases/Proteasome
Ethyl gallate (gallic acid ethyl ester) 是一种非类黄酮酚过氧化氢清除剂。
TN2015 Ophiopogonanone E

Others Others
Ophiopogonanone E has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.
TN5471 5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one

5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.It shows a strong cytotoxic activity on HeLa-S3 cell.
TN2013 Ophiopogonanone A

Others Others
Ophiopogonanone A has oxygen free radicals(OFRs) scavenging effects, it can scavenge hydroxyl radical(·OH) and hydrogen peroxide(H2O2) in vitro.
TN4935 Salvianolic acid Y

Others Others
Salvianolic acid Y 从丹参 Salvia officinalis 中分离出来,是 PC12 细胞免受过氧化氢诱导的丹参损伤的保护剂。

天然产物

(-​)​-​Salutaridine
Cat.No: T5760
Synonym: 清风藤碱,SINOACUTINE
Target: Others
4-methyl-6-phenyl-2H-pyranone
Cat.No: TN2436
Synonym: 4-methyl-6-phenyl-2H-pyranone
Target: Mitochondrial Metabolism
1-Methylguanidine hydrochloride
Cat.No: T4904
Synonym:
Target: Others, Endogenous Metabolite
Gigantol
Cat.No: TL0008
Synonym:
Target: Wnt/beta-catenin, Glucosidase
Ethyl gallate
Cat.No: T3729
Synonym: Nipagallin A,Phyllemblin,gallic acid ethyl ester,没食子酸乙酯
Target: MMP, NF-κB, Akt, Antibacterial
Ophiopogonanone E
Cat.No: TN2015
Synonym:
Target: Others
5,7-Dihydroxy-3-(4-hydroxy-3,5-dimethoxybenzyl)-6,8-dimethylchroman-4-one
Cat.No: TN5471
Synonym:
Target:
Ophiopogonanone A
Cat.No: TN2013
Synonym:
Target: Others
Salvianolic acid Y
Cat.No: TN4935
Synonym:
Target: Others
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