首页工具

登录

搜索结果

Search Results for " androgenic "

20

抑制剂 & 化合物

8

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T10140	4-Diethylaminobenzaldehyde	Dehydrogenase	Metabolism
	4-Diethylaminobenzaldehyde 是醛脱氢酶(ALDHs)的可逆抑制剂，对 ALDH1 的 Ki 为 4 nM，具有较强的抗雄激素作用，IC50为1.71 μM。
T0488	Finasteride 非那雄胺,MK-906	Reductase	Endocrinology/Hormones; Metabolism
	Finasteride (MK-906) 是 5α-还原酶的竞争性抑制剂，对 II 型 5α-还原酶的IC50为 4.2 nM，对 II 型 5α-还原酶的亲和力是 I 型酶的 100 倍。它可用于研究前列腺增生和雄激素性脱发。
T19213	Boldenone Cypionate	Others; Androgen Receptor	Endocrinology/Hormones; Others
	Boldenone Cypionate 是一种雄激素合成代谢类固醇，常被休闲健美运动员和普通健身房成员使用。
T14843	Bifluranol BX341	Androgen Receptor	Endocrinology/Hormones
	Bifluranol (BX341) 具有抗雄激素活性，在体内实验中显示出显著的抗前列腺活性，可用于治疗良性前列腺增生（BPH）。
T11410L	GLPG0492	Androgen Receptor	Endocrinology/Hormones
	GLPG0492 是一种非甾体选择性雄激素受体 (androgen receptor) 调节剂。GLPG0492 在肌肉骨骼疾病如肌萎缩和恶病质的研究方面具有潜在的潜力。
T1514	Norethindrone Norethisterone,炔诺酮	Estrogen/progestogen Receptor; Progesterone Receptor	Endocrinology/Hormones; Others
	Norethindrone (Norethisterone) 是孕激素，能够用于子宫内膜异位症、由激素水平异常引起的子宫出血和继发性闭经的研究。
T10889	CRTh2 antagonist 2	GPR	Endocrinology/Hormones; GPCR/G Protein
	CRTh2 antagonist 2 是一种有效的选择性 CRTH2 抑制剂，对 CRTH2 的 IC50 值为 ≤10 nM。CRTh2 antagonist 2 可用于雄激素性脱发的研究。
T30161	EN3356 AS N001,ASN-001	P450	Metabolism
	EN3356 是一种可口服且具有选择性的类固醇 17-α- 羟化酶/C17,20 裂解酶（CYP17A1 或 CYP17）抑制剂，是一种非甾体类裂解酶选择性化合物，具有潜在的抗雄激素和抗肿瘤活性。
T2556	Nandrolone decanoate 癸酸诺龙,19-Nortestosterone decanoate	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Nandrolone decanoate (19-Nortestosterone decanoate) 是一种合成代谢雄激素，通过涉及谷氨酸诱导的 N-甲基-D-天冬氨酸受体过度兴奋的机制诱导攻击性行为表征。
T25961	Piperophos Rilof
	Piperophos is an organophosphate with anti-androgenic activities.
T2195L	Epiandrosterone Sulfate Epiandrosterone 16-bromo,Epiandrosterone
	Epiandrosterone sulfate is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase of the adrenal hormone DHEA.
T25304	Demegestone R-2453,Lutionex,R 2453,RU 2453,R2453
	Demegestone is a progestin, or a synthetic progestogen, and hence is a progesterone receptor agonist, the biological target of progestogens like progesterone. It has no androgenic activity. Previously used to treat luteal insufficiency.
T19195	Androstenediol 17-acetate	Others	Others
	Androstenediol 17-acetate is a synthetic anabolic-androgenic steroid and an androgen ester.
T40809	2α-Methyl androsterone
	2α-Methyl androsterone is an anabolic androgenic steroid metabolite of mesterolone and drostanolone.
T81662	N-Nitrosodicyclohexylamine NDCHA	Androgen Receptor	Endocrinology/Hormones
	N-Nitrosodicyclohexylamine (NDCHA) 是一种N-亚硝基化合物，具有抗雄激素活性。它通过与雄激素受体 (AR) 竞争性结合来抑制 5α-二氢睾酮的作用，并能降低 AR 蛋白水平。
T73671	7β-Hydroxy-epi-androsterone
	7β-Hydroxy-epi-androsterone (7β-Hydroxy-EpiA) 是一种与ERβ结合的内源性雄激素衍生物，具有抗炎和神经保护特性。该化合物来源于dehydroepiandrosterone。
T21668	Finasteride acetate
	Finasteride (MK-906) acetate 是一种高效的5α-还原酶 (5α-reductase) 竞争性抑制剂，其对 II 型 5α-还原酶的IC50值仅为 4.2 nM，其对该型酶的亲和力是对 I 型酶亲和力的约100倍。因此，Finasteride acetate 主要在良性前列腺增生症 (BPH) 和雄激素性脱发研究领域中应用。
T61029	TP0427736 hydrochloride
	TP0427736 hydrochloride 可用于雄激素性脱发 (AGA) 研究。TP0427736 hydrochloride 可抑制由 TGF-β1 诱导的 A549 细胞中 Smad2/3 的磷酸化，IC50值为 8.68 nM。它也是ALK5激酶的有效抑制剂，IC50值为 2.72 nM，比对 ALK3 836 nM 的抑制作用高 300 倍。
T41331	Cyprodinil
	Cyprodinil 是一种苯胺嘧啶广谱杀菌剂，可抑制植物病原真菌蛋氨酸的生物合成。Cyprodinil 抑制B. cinerea，P. herpotrichoides，H. oryzae 的菌丝体细胞在无氨基酸的培养基上生长，IC50s 分别为 0.44，4.8，0.03 μM。在没有 AR 激动剂 DHT 的情况下，Cyprodinil 充当雄激素受体 (AR) 激动剂 (EC50=1.91 μM)，并抑制 DHT 的雄激素作用 (IC50=15.1 μM)。
T71142	Tebuconazole-d9
	Tebuconazole-d9 is intended for use as an internal standard for the quantification of tebuconazole by GC- or LC-MS. Tebuconazole is a triazole fungicide that is active against both seed and foliar fungi. It inhibits 14α-demethylase isolated from U. maydis and S. bicolor with IC50 values of 0.05 and 0.16 nM, respectively. It inhibits the androgenic effect of the androgen receptor agonist DHT (IC20 = 2.89 µM) and is cytotoxic (EC20 = 38.9 µM) in an MDA-kb2 assay. Tebuconazole (50 and 100 mg/kg per...

化合物

4-Diethylaminobenzaldehyde

Cat.No: T10140

Target: Dehydrogenase

Cat.No: T0488

Synonym: 非那雄胺,MK-906

Target: Reductase

Boldenone Cypionate

Cat.No: T19213

Target: Others, Androgen Receptor

Cat.No: T14843

Synonym: BX341

Target: Androgen Receptor

Cat.No: T11410L

Target: Androgen Receptor

Cat.No: T1514

Synonym: Norethisterone,炔诺酮

Target: Estrogen/progestogen Receptor, Progesterone Receptor

CRTh2 antagonist 2

Cat.No: T10889

Target: GPR

Cat.No: T30161

Synonym: AS N001,ASN-001

Target: P450

Nandrolone decanoate

Cat.No: T2556

Synonym: 癸酸诺龙,19-Nortestosterone decanoate

Target: Others, HIV Protease

Cat.No: T25961

Synonym: Rilof

Epiandrosterone Sulfate

Cat.No: T2195L

Synonym: Epiandrosterone 16-bromo,Epiandrosterone

Cat.No: T25304

Synonym: R-2453,Lutionex,R 2453,RU 2453,R2453

Androstenediol 17-acetate

Cat.No: T19195

Target: Others

2α-Methyl androsterone

Cat.No: T40809

N-Nitrosodicyclohexylamine

Cat.No: T81662

Synonym: NDCHA

Target: Androgen Receptor

7β-Hydroxy-epi-androsterone

Cat.No: T73671

Finasteride acetate

Cat.No: T21668

TP0427736 hydrochloride

Cat.No: T61029

Cat.No: T41331

Tebuconazole-d9

Cat.No: T71142

Cat. No.	Product Name	Target	Signaling Pathways
T19470	Nandrolone propionate	Others; Androgen Receptor	Endocrinology/Hormones; Others
	Nandrolone propionate 是合成代谢类固醇，主要由雄激素和保氮剂组成，具有作用时间相对较长的特点。
T2207	Adrenosterone 肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G	Androgen Receptor; Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Adrenosterone (11-ketoandrostenedione) 是一种人内源性代谢物，由肾上腺皮质产生。Adrenosterone 是一种竞争性羟基类固醇脱氢酶 1 抑制剂。它是一种的类固醇激素，具有较弱的雄激素特性。它是一种膳食补充剂，能够减少脂肪并提高肌肉质量。它能够抑制人类癌细胞的转移进展。
TC0026	Testosterone benzoate	Others	Others
	Testosterone benzoate 是一种合成的注射合成代谢雄激素类固醇 (AAS) 和一种雄激素酯。
T7957	2-Isopropyl Thioxanthone	Others	Others
	2-Isopropyl Thioxanthone 具有潜在的抗雌激素和抗雄激素特性。
T1284	Megestrol acetate SC10363,醋酸甲地孕酮,BDH1298	Glucocorticoid Receptor; Estrogen/progestogen Receptor; Progesterone Receptor; HIV Protease; Autophagy	Autophagy; Endocrinology/Hormones; Microbiology/Virology; Others; Proteases/Proteasome
	Megestrol acetate (BDH1298) 是具有口服活性的合成孕激素。它还具有抗雄激素特性，可用于治疗厌食症和恶病质。
T20976	Clostebol acetate Clostebolacetate,Clostene,Alfa-Trofodermin,4-CLTA
	Clostebol acetate is a synthetic anabolic-androgenic steroid (AAS) and a derivative of testosterone. It acts as a prodrug of clostebol in the body.
T19716	1,3,5-Trihydroxyxanthone
	1,3,5-Trihydroxyxanthone is a highly cytotoxic natural compound. It against a range of bacteria and yeasts.Anti-androgenic.
TN4604	Myricanone	BCL; HSP; NF-κB; ROS; Caspase; STAT	Apoptosis; Cytoskeletal Signaling; Immunology/Inflammation; JAK/STAT signaling; Metabolism; NF-κB; Proteases/Proteasome; Stem Cells
	Myricanone has antioxidant, and anticancer activities, it has apoptosis-promoting ability by triggering caspase activation, and suppression of cell proliferation by down-regulation of NF-ÎºB and STAT3 signalling cascades. Myricanone shows in vitro testost

天然产物

Nandrolone propionate

Cat.No: T19470

Target: Others, Androgen Receptor

Cat.No: T2207

Synonym: 肾上腺甾酮,11-ketoandrostenedione,11-oxoandrostenedione,Reichstein's substance G

Target: Androgen Receptor, Endogenous Metabolite

Testosterone benzoate

Cat.No: TC0026

Target: Others

2-Isopropyl Thioxanthone

Cat.No: T7957

Target: Others

Megestrol acetate

Cat.No: T1284

Synonym: SC10363,醋酸甲地孕酮,BDH1298

Target: Glucocorticoid Receptor, Estrogen/progestogen Receptor, Progesterone Receptor, HIV Protease, Autophagy

Clostebol acetate

Cat.No: T20976

Synonym: Clostebolacetate,Clostene,Alfa-Trofodermin,4-CLTA

1,3,5-Trihydroxyxanthone

Cat.No: T19716

Cat.No: TN4604

Target: BCL, HSP, NF-κB, ROS, Caspase, STAT

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼