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51

抑制剂 & 化合物

7

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Cat. No. Product Name Target Signaling Pathways
T14169 Ald-Ph-PEG6-acid

Others Others
Ald-Ph-PEG6-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T17061 Tetrazine-Ph-acid

Others Others
Tetrazine-Ph-acid is an alkyl chain-derived PROTAC linker employed in PROTAC synthesis[1].
T17370 Ald-Ph-amido-PEG24-acid

Others Others
Ald-Ph-amido-PEG24-acid is a polyethylene glycol (PEG)-based linker used for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T14171 Ald-Ph-amido-PEG2-C2-acid

Others Others
Ald-Ph-amido-PEG2-C2-acid is a PEG-based PROTAC linker utilized for synthesizing PROTACs[1].
T14174 Ald-Ph-amido-PEG4-C2-acid

Others Others
Ald-Ph-amido-PEG4-C2-acid is a noncleavable linker utilized in the development of antibody-drug conjugates (ADC).
T5203 Sodium Tartrate

Others Others
Sodium Tartrate 是一种的 pH 调节剂,具有抗氧化活性,能够有效延缓高温加热时的水解,使植物油的酸值增加。
T9680 Irloxacin

Antibacterial Microbiology/Virology
Irloxacin 是一种口服活性的喹诺酮类抗菌剂,在酸性条件下具有更强大的活性。在体外,Irloxacin 对革兰氏阳性菌和革兰氏阴性菌都具有良好的抗菌谱。
T18624 NH2-Ph-C4-acid-NH2-Me

PROTAC Linker 31

Others Others
NH2-Ph-C4-acid-NH2-Me (PROTAC Linker 31) is an alkyl chain-based compound utilized for the synthesis of PROTACs. [1]
T22229 Acid Yellow 36

Metanil Yellow,酸性黄36

Others Others
Acid Yellow 36 (Metanil Yellow) 是一种偶氮染料和 pH 指示剂,当 pH 值从 1.2 到 2.3 时,发生由红色到黄色的颜色转变。它是 P-450 特异性同工酶和胞浆酶的双功能诱导剂,可用于皮革、造纸和纺织工业。
T21481 Bromophenol Blue

Others Others
Bromophenol blue 是酸性酞菁染料,可用作电泳的示踪染料。它也是一种 pH 指示剂,pH 指示范围是 3 到 4.6 之间。
T40545 MES

2-Morpholinoethanesulphonic acid,4-Morpholineethanesulfonic acid

Others Others
MES (2-Morpholinoethanesulphonic acid) (2-Morpholinoethanesulphonic acid) 是一种两性离子缓冲液,在 pH 值 5.5-7.7 范围内有效。MES 作为一种 Good's 缓冲液,广泛应用于植物培养基、试剂溶液和生理实验中调节 pH 值。
T38509 MOPS

3-(N-Morpholino)propanesulfonic acid,3-吗啉丙磺酸,3-Morpholinopropanesulfonic acid,4-Morpholinepropanesulfonic acid,Morpholinopropane sulfonic acid

Others Others
MOPS(Morpholinopropane sulfonic acid),作为一种广泛应用的生物缓冲剂,有效调节哺乳动物细胞培养基的pH值。
T8617 GMQ hydrochloride

NSC 403387 hydrochloride

Others Others
GMQ hydrochloride (NSC-403387 hydrochloride) 是一种有效的选择性酸感应离子通道 (ASIC) 调节剂。它在中性 pH 值下激活 ASIC3 通道并阻止酸引起的最大峰值电流。
T8549 HEPES

Others Others
HEPES 是两性离子化学缓冲剂,在 pH 值为 6.8 至 8.2 时为有效的缓冲液,广泛应用于细胞培养。它是溶酶体生物发生的有效诱导剂。
T8885 5-Ph-IAA

Others Others
5-Ph-IAA 是一种 IAA 的衍生物,是一种配体与 OsTIR1 (F74G) 突变体一起建立了生长素诱导的 degron 2 系统 (AID2)。AID2 能够诱导 mAID 融合蛋白的快速有效消耗,从而研究活细胞中的蛋白功能,具有抑制肿瘤的作用。
T21254 Vonoprazan Fumarate

TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞

Proton pump Membrane transporter/Ion channel
Vonoprazan Fumarate (TAK438) 是质子泵的有效抑制剂,是口服有效的高效钾竞争性酸阻断剂,具有抗分泌活性。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50为 19 nM。它被开发用于研究酸相关疾病,如消化性溃疡和胃食管反流病。
T19820 MOPS sodium salt

MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt

Others Others
MOPS sodium salt (MOPS-Na) 在生物学中常用作缓冲剂。其中MOPS 缓冲液能使哺乳动物细胞培养基的 pH 值保持稳定。
T18893 5(6)-Carboxyfluorescein

5(6)-羧基荧光素,5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM

Others Others
5(6)-Carboxyfluorescein (5-(and-6)-Carboxyfluorescein mixed isomers) 是一种胺反应性 pH 敏感的绿色荧光标记物,能够标记蛋白质、多肽和氨基酸,可用于体内实验检测肿瘤位置。
TP2505L LAH4 acetate

KKALLALALHHLAHLALHLALALKKA acetate,LAH4 acetate(184776-51-0 Free base)

Antibacterial Microbiology/Virology
LAH4 acetate 是所设计的两性肽抗生素的α -螺旋结构,能够与DNA 络合,与细胞表面膜结合后被包裹在核内体中,随着pH 值的下降破坏核内体膜。具有强大的抗菌、核酸转染和细胞渗透活性。LAH4 acetate 具有较高的质粒DNA 传递能力。LAH4 acetate 对细菌膜外膜中的阴离子脂具有很强的亲和力。
T3627 IQ-1S free acid

IQ-1,IQ-1S,IQ-1S (free acid)

NF-κB; JNK MAPK; NF-κB
IQ-1S free acid (IQ-1S) 是 NF-κB/激活蛋白1 (AP-1) 抑制剂(IC50:2.3±0.41 μM)。它对 JNK1(Kd:240 nM)、JNK2(Kd:360 nM) 和 JNK3(Kd:100 nM)的都具有高的结合亲和力 。
T8388 Vonoprazan

TAK-438 (free base),沃诺拉赞

Proton pump Membrane transporter/Ion channel
Vonoprazan (TAK-438 (free base)) 是一种质子泵抑制剂,是口服活性钾竞争性酸阻断剂,有抗分泌作用。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50值为 19 nM。它可用于研究胃酸相关疾病。
T0961 Trometamol

三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵

COX Immunology/Inflammation; Neuroscience
Trometamol (Tromethamine) 是一种在生理范围内控制 pH 值的有效胺类化合物,也是一种低毒性的生物惰性氨基醇,可以在体内和体外缓冲二氧化碳和酸。
T36587 8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt

Others Others
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt 是一种阴离子荧光染料,用作葡萄糖传感和检测其他糖类的报告分子。激发/发射光谱为 425/503 nm。 它可以在溶液中使用,也可以通过还原胺化连接醛官能化单体来固定,而不会显著改变荧光强度。
T6929 Pantoprazole sodium

Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc

Apoptosis; Others; Proton pump; HIF; Autophagy Angiogenesis; Apoptosis; Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Others
Pantoprazole sodium (Pantecta) 是一种具有口服活性的质子泵抑制剂,是一种取代的苯并咪唑,是H+/K+-ATPase 抑制剂,IC50为 6.8 μM。它可以改善 pH 值稳定性,具有抗分泌和抗溃疡的作用。它联合阿霉素可显著增加肿瘤生长延迟。
T39362 OG 488, acid

OG 488, a fluorescent pH indicator (acid), is widely used in biochemistry and neurosciences, offering numerous applications.
T28156 Nepaprazole

TY-11345,TY11345,TY 11345

Nepaprazole is a proton pump inhibitor. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated rabbit gastric mucosal microsomes, and the inhibitory effect was enhanced under weak acid conditions, the IC50 being 5.8 microM and 9.9 microM at pH 6.
T38124 Piloty's Acid

Nitric Oxide (NO) is a free radical gas that is involved in a variety of biological processes including regulation vascular tone, neuronal signaling, and host defense. Nitroxyl (HNO) is the one electron reduced form of nitric oxide. Piloty's acid is one of the best known and most widely used HNO donors. Under basic conditions Piloty's acid decomposes to HNO and benzenesulfinate anion. The rate of HNO release at pH 7 is very slow (t = 5,500 minutes) making its use most effective above pH 8.0. Th...
T40819 MES sodium salt

2-Morpholinoethanesulphonic acid sodium salt

MES (2-Morpholinoethanesulphonic acid) sodium salt, a zwitterionic buffer, is effective in the pH range of 5.5-7.7. MES sodium salt, as one of the Good’s buffers, is broadly used to regulate pH value for plants culture medium, reagent solution, and physiological experiments.
T40851 ACES

N-氨基甲酰甲基乙磺酸,N-(2-Acetamido)-2-aminoethanesulfonic acid

ACES, or N-(2-Acetamido)-2-aminoethanesulfonic acid, is a zwitterionic buffer compound. It offers an effective pH range of 6.8-7.2 for various applications.
T80705 α-Naphtholbenzein

p-Naphtolbenzein

α-Naphtholbenzein (p-Naphtolbenzein) 是一种可作为pH指示剂使用的染料,具有pH0至8.2范围内呈现黄色、pH10时转变为青绿色的视觉过度特性,常应用于酸碱滴定。
TD0075 7-Hydroxy-4-methylcoumarin-3-acetic acid

7-Hydroxy-4-methylcoumarin-3-acetic acid is a blue fluorophore that has pH-dependent and environment-sensitive fluorescence. This coumarin is increasingly used to label peptides, nucleotides and carbohydrates.
T80181 MitTx-alpha

Sodium Channel Membrane transporter/Ion channel
MitTx-alpha为MitTx的亚基,该化合物为一高效、持久、选择性酸敏感离子通道(ASIC)激动剂。该化合物在中性pH条件下优先选择ASIC1亚型,而在更酸性条件(pH<6.5)时,可显著增强(>100倍)质子诱导的ASIC2a通道活性。
T36370 4-Methylumbelliferyl-α-L-Iduronide (free acid)

4-Methylumbelliferyl-α-L-iduronide (free acid) is a fluorogenic substrate for α-L-iduronidase, an enzyme found in cell lysosomes that is involved in the degradation of glycosaminoglycans such as dermatan sulfate and heparin sulfate. 4-Methylumbelliferyl-α-L-iduronide is cleaved by α-L-iduronidase to release the fluorescent moiety 4-methylumbelliferyl (4-MU). 4-MU fluorescence is pH-dependent with excitation maxima of 320 and 360 nm at low (1.97-6.72) and high (7.12-10.3) pH, respectively, and an...
T39432 HKOCl-4

HKOCl-4,BXY2142

HKOCl-4 (BXY2142) is a rhodol-based yellow fluorescent probe that demonstrates exceptional sensitivity and selectivity in detecting hypochlorous acid. Its absorption wavelength is significantly longer than that of fluorescein-based probes, and it exhibits better pH stability. Notably, HKOCl-4 exhibits excitation at 530 nm and emission at 557 nm.
T20014 Patent Blue V calcium salt

Acid blue 3,L-Blau 3,Food Blue 3,Blue ZN 3,NSC 5010,C.I. 42051

Acid blue is a dark bluish synthetic triphenylmethane dye. It used as a food coloring. The color of the dye is pH-dependent. The structure is also redox-sensitive, changing from a reduced yellow form to an oxidized red form in solution. It is usable as a
T38952 Triperiden

Triperiden is a chemical compound that serves as an inhibitor of influenza virus multiplication. Specifically, it exerts its antiviral activity by targeting the haemagglutinin of fowl plague virus (FPV) and inhibiting the conformational change in the haemagglutinin at acid pH. Additionally, Triperiden is classified as an anticholinergic anti-parkinsonism drug.
T70428 Nepaprazole sodium

Nepaprazole Na is the salt form of Nepaprazole Free Base, also known as TY-11345, is a proton pump inhibitor potentially for treatment of gastric ulcer. TY-11345 potently inhibited H+/K(+)-ATPase activity in isolated rabbit gastric mucosal microsomes; and the inhibitory effect was enhanced under weak acid conditions, the IC50 (concentrations that inhibit the enzyme activity by 50%) being 5.8 microM and 9.9 microM at pH 6.0 and pH 7.4, respectively. TY-11345 should be useful for the clinical tre...
T80429 π-TRTX-Hm3a

Sodium Channel Membrane transporter/Ion channel
π-TRTX-Hm3a 是一种含有37个氨基酸的肽,源自多哥星暴狼蛛 (Heteroscodra maculata) 的毒液。该化合物 pH 依赖性抑制酸敏感离子通道 1a (ASIC1a),其 IC50 值为 1-2 nM,并且能够增强 ASIC1b 的活性,EC50 值为 46.5 nM。
T83550 (Asp28)-Glucagon (1-29) (human, rat, porcine)

'(Asp28)-Glucagon (1-29) (human, rat, porcine)' 为胰高血糖素的一种改良型结构,在第28位氨基酸残基上天冬氨酸(Asp)替换原有残基,显著提高了该化合物在生理pH条件下的溶解性,且保持了与天然胰高血糖素相同的生物活性。
T75377 Thymolphthalein monophosphate disodium hydrate

Thymolphthalein monophosphate disodium hydrate 是用于测定酸性及碱性磷酸酶显色底物。反应过程中释放的百里酚酞可增加介质pH,促使颜色产生并终止水解作用,特别适合于血清中前列腺磷酸酶的特异性检测。
T61643 Vonoprazan hydrochloride

Vonoprazan hydrochloride 是一种高效且具口服活性的质子泵抑制剂 (PPI) 和钾竞争性酸阻断剂 (potassium-competitive acid blocker, P-CAB),展示出优秀的抗分泌活性。在 pH 为 6.5 的条件下,该化合物可抑制猪胃微粒体内 H+,K+-ATPase 的酶活性,呈现出 19 nM 的 IC50 值。Vonoprazan hydrochloride 主要应用于胃酸相关疾病的研究,包括胃食管反流病和消化性溃疡,并可用于根除幽门螺杆菌。
T39548 Amustaline dihydrochloride

S-303 dihydrochloride

Amustaline (S-303) dihydrochloride is a nucleic acid-targeted alkylator recognized for its efficacy as a pathogen inactivation agent in blood components containing red blood cells. This compound comprises three key elements: an acridine anchor (a non-covalently bonding intercalator targeting nucleic acids), an effector (a bis-alkylator group that interacts with nucleophiles), and a linker (a flexible carbon chain with a labile ester bond, hydrolyzing at neutral pH to non-reactive products).
T36714 Sucrose octasulfate (potassium salt)

Sucrose octasulfate (SOS), a component of the gastrointestinal protectant sucralfate, is an alkaline aluminum-sucrose complex that inhibits peptic hydrolysis and raises gastric pH, protecting esophageal epithelium against acid injury. It can bind to exosite II of thrombin (KD = ~1.4 μM) and inhibit its catalytic activity (IC50 = 4.5 μM) and, as such, has been used as a surrogate for heparin. Furthermore, SOS has been shown to inhibit tumor growth in mouse melanoma and lung carcinoma models by pr...
T35922 NAADP (sodium salt)

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a secondary messenger that induces calcium mobilization. It induces calcium release from endosomes and lysosomes via two-pore channel 2 (TPC2) and TPC1, which then stimulates large-scale calcium release from granules and the endoplasmic reticulum mediated by type 1 ryanodine receptors (RyR2s), RyR3s, and inositol-(1,4,5)-triphosphate receptors (IP3Rs). NAADP induces calcium mobilization in sea urchin and starfish eggs post fertilization to...
T79586 3′-Acetate-ATP

3’-Acetate-ATP为ATP的乙酰化衍生物,表现为ATP类似物,其在中性pH值的水溶液中于259 nm波长处展现出最大的紫外线吸收。该化合物能够抑制核酸聚合酶活性,从而阻断核酸的延伸。
TMIH-0601 Vonoprazan-d3

Vonoprazan-d3 是 Vonoprazan 的氘代化合物。Vonoprazan 的 CAS 号为 881681-00-1。Vonoprazan 是一种质子泵抑制剂,是口服活性钾竞争性酸阻断剂,有抗分泌作用。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50值为 19 nM。它可用于研究胃酸相关疾病。
T36939 PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)

PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)

The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transd...
T8761 [Leu15]-Gastrin I human

Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2

Others Others
[Leu15]-Gastrin I human (Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2) 基因编码人体内的蛋白质 [Leu15]-胃泌素 I。在人类染色体中,GAST 基因定位于 17q21.2。胃窦中的 G 细胞产生 [Leu15]-胃泌素 I 的前体前胃泌素。前胃泌素经过裂解和加工产生胃泌素,它对整个胃肠道上皮细胞具有营养作用。胃泌素对消化系统的生长至关重要,并刺激壁细胞产生胃酸。胃泌素通过称为胆囊收缩素(CCK) 或 CCK-B 受体 (CCK-BR) 的 G 蛋白偶联受体发挥其功能。胃泌素的释放受到食物的刺激,尤其是蛋白质饮食,并受到非常低的 pH 值的抑制。萎缩性胃炎、幽门螺杆菌感染和长期服用质子泵抑制剂感染可能导致胃泌素过度表达。胃腺癌显示高水平的胃泌素。
TMIH-0602 Vonoprazan-d4

Vonoprazan-d4 是 Vonoprazan 的氘代化合物。Vonoprazan 的 CAS 号为 881681-00-1。Vonoprazan 是一种质子泵抑制剂,是口服活性钾竞争性酸阻断剂,有抗分泌作用。在 pH 为 6.5 时,它抑制猪胃微粒体中的 H+,K+-ATPase 酶活性,IC50值为 19 nM。它可用于研究胃酸相关疾病。
T83314 4-Methylumbelliferyl palmitate

4-Methylumbelliferyl palmitate 是用于测量人白细胞中酸性脂肪酶的优良荧光探针。该化合物的荧光特性受pH值和溶剂类型的显著影响。在近中性水溶液中,4-Methylumbelliferyl palmitate 以中性形态存在,并在445 nm发射较强荧光;而在微弱碱性环境中,则以阴离子形态存在,同样在445 nm处展现较强的荧光。

化合物

Ald-Ph-PEG6-acid
Cat.No: T14169
Synonym:
Target: Others
Tetrazine-Ph-acid
Cat.No: T17061
Synonym:
Target: Others
Ald-Ph-amido-PEG24-acid
Cat.No: T17370
Synonym:
Target: Others
Ald-Ph-amido-PEG2-C2-acid
Cat.No: T14171
Synonym:
Target: Others
Ald-Ph-amido-PEG4-C2-acid
Cat.No: T14174
Synonym:
Target: Others
Sodium Tartrate
Cat.No: T5203
Synonym:
Target: Others
Irloxacin
Cat.No: T9680
Synonym:
Target: Antibacterial
NH2-Ph-C4-acid-NH2-Me
Cat.No: T18624
Synonym: PROTAC Linker 31
Target: Others
Acid Yellow 36
Cat.No: T22229
Synonym: Metanil Yellow,酸性黄36
Target: Others
Bromophenol Blue
Cat.No: T21481
Synonym:
Target: Others
MES
Cat.No: T40545
Synonym: 2-Morpholinoethanesulphonic acid,4-Morpholineethanesulfonic acid
Target: Others
MOPS
Cat.No: T38509
Synonym: 3-(N-Morpholino)propanesulfonic acid,3-吗啉丙磺酸,3-Morpholinopropanesulfonic acid,4-Morpholinepropanesulfonic acid,Morpholinopropane sulfonic acid
Target: Others
GMQ hydrochloride
Cat.No: T8617
Synonym: NSC 403387 hydrochloride
Target: Others
HEPES
Cat.No: T8549
Synonym:
Target: Others
5-Ph-IAA
Cat.No: T8885
Synonym:
Target: Others
Vonoprazan Fumarate
Cat.No: T21254
Synonym: TAK-438,TAK 438,Vonoprazan Fumurate,TAK438,富马酸沃诺拉赞
Target: Proton pump
MOPS sodium salt
Cat.No: T19820
Synonym: MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt
Target: Others
5(6)-Carboxyfluorescein
Cat.No: T18893
Synonym: 5(6)-羧基荧光素,5-(and-6)-Carboxyfluorescein mixed isomers,5(6)-FAM
Target: Others
LAH4 acetate
Cat.No: TP2505L
Synonym: KKALLALALHHLAHLALHLALALKKA acetate,LAH4 acetate(184776-51-0 Free base)
Target: Antibacterial
IQ-1S free acid
Cat.No: T3627
Synonym: IQ-1,IQ-1S,IQ-1S (free acid)
Target: NF-κB, JNK
Vonoprazan
Cat.No: T8388
Synonym: TAK-438 (free base),沃诺拉赞
Target: Proton pump
Trometamol
Cat.No: T0961
Synonym: 三(羟甲基)氨基甲烷,Tromethamine,缓血酸铵
Target: COX
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt
Cat.No: T36587
Synonym:
Target: Others
Pantoprazole sodium
Cat.No: T6929
Synonym: Pantecta,泮托拉唑钠盐,SKF96022 sodium,SKF96022 (sodium),BY1023 (sodium),泮托拉唑钠,BY-1023 sodium,Pantoloc
Target: Apoptosis, Others, Proton pump, HIF, Autophagy
OG 488, acid
Cat.No: T39362
Synonym:
Target:
Nepaprazole
Cat.No: T28156
Synonym: TY-11345,TY11345,TY 11345
Target:
Piloty's Acid
Cat.No: T38124
Synonym:
Target:
MES sodium salt
Cat.No: T40819
Synonym: 2-Morpholinoethanesulphonic acid sodium salt
Target:
ACES
Cat.No: T40851
Synonym: N-氨基甲酰甲基乙磺酸,N-(2-Acetamido)-2-aminoethanesulfonic acid
Target:
α-Naphtholbenzein
Cat.No: T80705
Synonym: p-Naphtolbenzein
Target:
7-Hydroxy-4-methylcoumarin-3-acetic acid
Cat.No: TD0075
Synonym:
Target:
MitTx-alpha
Cat.No: T80181
Synonym:
Target: Sodium Channel
4-Methylumbelliferyl-α-L-Iduronide (free acid)
Cat.No: T36370
Synonym:
Target:
HKOCl-4
Cat.No: T39432
Synonym: HKOCl-4,BXY2142
Target:
Patent Blue V calcium salt
Cat.No: T20014
Synonym: Acid blue 3,L-Blau 3,Food Blue 3,Blue ZN 3,NSC 5010,C.I. 42051
Target:
Triperiden
Cat.No: T38952
Synonym:
Target:
Nepaprazole sodium
Cat.No: T70428
Synonym:
Target:
π-TRTX-Hm3a
Cat.No: T80429
Synonym:
Target: Sodium Channel
(Asp28)-Glucagon (1-29) (human, rat, porcine)
Cat.No: T83550
Synonym:
Target:
Thymolphthalein monophosphate disodium hydrate
Cat.No: T75377
Synonym:
Target:
Vonoprazan hydrochloride
Cat.No: T61643
Synonym:
Target:
Amustaline dihydrochloride
Cat.No: T39548
Synonym: S-303 dihydrochloride
Target:
Sucrose octasulfate (potassium salt)
Cat.No: T36714
Synonym:
Target:
NAADP (sodium salt)
Cat.No: T35922
Synonym:
Target:
3′-Acetate-ATP
Cat.No: T79586
Synonym:
Target:
Vonoprazan-d3
Cat.No: TMIH-0601
Synonym:
Target:
PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)
Cat.No: T36939
Synonym: PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)
Target:
[Leu15]-Gastrin I human
Cat.No: T8761
Synonym: Amino Acid Sequence Glp-Gly-Pro-Trp-Leu-Glu-Glu-Glu-Glu-Glu-Ala-Tyr-Gly-Trp-Leu-Asp-Phe-NH2
Target: Others
Vonoprazan-d4
Cat.No: TMIH-0602
Synonym:
Target:
4-Methylumbelliferyl palmitate
Cat.No: T83314
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
T2805 Chlorogenic Acid

NSC-407296,3-O-Caffeoylquinic acid,Heriguard,绿原酸

Others; Influenza Virus; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; Endogenous Metabolite; Antibacterial Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others
Chlorogenic Acid (NSC-407296) 是咖啡和茶中的主要酚类化合物。它具有多种生物作用。
T5S1569 AKBA

乙酰基-11-酮基-beta-乳香酸,3-O-Acetyl-11-keto-β-boswellic acid,3-O-Acetyl-11-keto-beta-boswellic acid,Acetyl-11-keto-β-boswellic acid

Others; Reactive Oxygen Species; HIF/HIF Prolyl-Hydroxylase; Endogenous Metabolite Chromatin/Epigenetic; Immunology/Inflammation; Metabolism; NF-κB; Others
AKBA (3-O-Acetyl-11-keto-beta-boswellic acid) 是一种从乳香中分离的天然成分,是新颖的 Nrf2 的活化剂。
T11589 Hydroxycitric acid tripotassium hydrate

柠檬酸钾一水合物,三水合钾柠檬酸,Potassium citrate monohydrate

ATP Citrate Lyase; HIF/HIF Prolyl-Hydroxylase; HIF Angiogenesis; Chromatin/Epigenetic; Metabolism
Hydroxycitric acid tripotassium hydrate (Potassium citrate monohydrate) 是一种藤黄果的主要活性成分,也是一种柠檬酸的衍生物。它可竞争性抑制柠檬酸裂解酶 (ATP citrate lyase) ,并具有减肥作用。它有效抑制结石形成,并抑制HIF,具有抗氧化,抗炎和抗肿瘤活性。
T0256 Citric acid trilithium salt tetrahydrate

Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate

Dehydrogenase; GSK-3; HIF/HIF Prolyl-Hydroxylase; Antibacterial; GluR Chromatin/Epigenetic; Metabolism; Microbiology/Virology; Neuroscience; PI3K/Akt/mTOR signaling; Stem Cells
Citric acid trilithium salt tetrahydrate (Lithium citrate tribasic tetrahydrate) 是一种用于治疗精神疾病的药物。它也是一种医药和建筑材料, 可用于氨基酸定量分析时的梯度洗脱。
T19284 Dimethylmalonic acid

2,2-Dimethylmalonic acid

Endogenous Metabolite Metabolism
Dimethylmalonic acid(2,2-Dimethylmalonic acid) 是人血清中的短链二羧酸,可用于预防或延缓鱼肌动球蛋白在冷冻缓冲溶液(pH 7)中的变性。
T2958 D-(-)-Quinic acid

Quinate,Kinic acid,Chinic acid,Quinic acid,奎尼酸

Others; Endogenous Metabolite Metabolism; Others
D-(-)-Quinic acid (Kinic acid) 是一种环己基羧酸,含量与咖啡的酸度有关。
T0542 Isohomovanillic acid

3-羟基-4-甲氧基苯乙酸,Homoisovanillic acid

Others; Endogenous Metabolite Metabolism; Others
Isohomovanillic acid (Homoisovanillic acid) 是一种由乙酸乙酯在 pH 值为 2 的条件下从尿液中提取而来,在许多正常人尿中并不明显。

天然产物

Chlorogenic Acid
Cat.No: T2805
Synonym: NSC-407296,3-O-Caffeoylquinic acid,Heriguard,绿原酸
Target: Others, Influenza Virus, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite, Antibacterial
AKBA
Cat.No: T5S1569
Synonym: 乙酰基-11-酮基-beta-乳香酸,3-O-Acetyl-11-keto-β-boswellic acid,3-O-Acetyl-11-keto-beta-boswellic acid,Acetyl-11-keto-β-boswellic acid
Target: Others, Reactive Oxygen Species, HIF/HIF Prolyl-Hydroxylase, Endogenous Metabolite
Hydroxycitric acid tripotassium hydrate
Cat.No: T11589
Synonym: 柠檬酸钾一水合物,三水合钾柠檬酸,Potassium citrate monohydrate
Target: ATP Citrate Lyase, HIF/HIF Prolyl-Hydroxylase, HIF
Citric acid trilithium salt tetrahydrate
Cat.No: T0256
Synonym: Lithium citrate tribasic tetrahydrate,柠檬酸三锂盐四水合物,Trilithium citrate tetrahydrate
Target: Dehydrogenase, GSK-3, HIF/HIF Prolyl-Hydroxylase, Antibacterial, GluR
Dimethylmalonic acid
Cat.No: T19284
Synonym: 2,2-Dimethylmalonic acid
Target: Endogenous Metabolite
D-(-)-Quinic acid
Cat.No: T2958
Synonym: Quinate,Kinic acid,Chinic acid,Quinic acid,奎尼酸
Target: Others, Endogenous Metabolite
Isohomovanillic acid
Cat.No: T0542
Synonym: 3-羟基-4-甲氧基苯乙酸,Homoisovanillic acid
Target: Others, Endogenous Metabolite
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