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Search Results for " veratrum "

3

抑制剂 & 化合物

11

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T34797	Teinemine Muldamine,Deacetylmuldame,Deacetylmuldamine
	Teinemine also known as Muldamine, is a phytosterol alkaloid isolated from Veratrum californicum. It is the acetate ester of the piperidine steroid teinemine.
T3363L	Jervine HCl Jervine hydrochloride
	Jervine is a naturally occurring steroidal alkaloid derived from the Veratrum plant species. Over the Hedgehog signaling pathway, Jervine effectively inhibits tumor growth using three human tumor xenograft models. Jervine has the potential to advance to t
T78058	Verazine (-)-Verazine
	Verazine ((-)-Verazine) 是抗真菌剂，源自干燥毛穗藜芦根及根茎。该药物能剂量依赖地引发小鼠小脑与大脑皮层DNA损伤，且适用于真菌感染和神经疾病研究。

化合物

Cat.No: T34797

Synonym: Muldamine,Deacetylmuldame,Deacetylmuldamine

Cat.No: T3363L

Synonym: Jervine hydrochloride

Cat.No: T78058

Synonym: (-)-Verazine

Cat. No.	Product Name	Target	Signaling Pathways
T3363	Jervine 蒜黎芦碱,Iervin,11-Ketocyclopamine,Jerwiny	Hedgehog/Smoothened; Smo	GPCR/G Protein; Stem Cells
	Jervine (Jerwiny) 是一种有效的刺猬 (Hh) 抑制剂(IC50:500-700 nM)。它是一种天然致畸性甾体生物碱，来自于 Veratrumalbum 的根茎，具有抗炎和抗氧化作用。
TN1057	Veratrosine 藜芦托素,Veratramine 3-glycoside,Veratramine-beta-D-glucoside	Platelet aggregation	Others
	Veratrosine (Veratramine-beta-D-glucoside) 是一种从藜芦草本植物中分离出来的生物碱。 Veratrosine 对血小板聚集表现出微弱的抑制活性。
TN2343	Pseudojervine Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine,假白藜芦碱	Platelet aggregation	Others
	Pseudojervine (O-beta-D-Glucopyranosyljervine) 来源于 Veratrum nigrum L. Pseudojervine 对血小板聚集表现出微弱的抑制活性。
T2173	Veratridine	Sodium Channel	Membrane transporter/Ion channel
	Veratridine 是一种生物碱，来自百合科植物。Veratridine 是一种钠通道激动剂，对 Nav1.7 的峰值电流具有抑制作用，IC50为 18.39 µM。
T82262	Grandivine A
	Grandivine A, 类固醇生物碱, 源自毛叶藜芦 (Veratrum grandiflorum) 分离。
T82009	Jervinone
	Jervinone，一种从霉菌 Cunninghamella echinulata 分离得到的Veratrum生物碱代谢物。
T39854	Cycloposine
	Cycloposine, a steroidal alkaloid present in the roots and rhizomes of Veratrum californicum, is known to possess teratogenic properties.
T0568	3,4-Dimethoxyphenylacetic acid Homoveratrumic acid,homoveratric acid,高藜芦酸	Others; Endogenous Metabolite	Metabolism; Others
	3,4-Dimethoxyphenylacetic acid (Homoveratrumic acid) 是一种化学合成中的砌块。
T3744	Veratric acid Veratrumenoic acid,藜芦酸,3,4-Dimethoxybenzoic acid	Reactive Oxygen Species; COX	Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Veratric acid (3,4-Dimethoxybenzoic acid) 是从蔬菜和水果中得到的一种可口服多酚，具有抗氧化、保护心血管和抗炎活性。当细胞受到 UVB 辐射时，它能够减少上调的 COX-2 表达，降低 PGE2 和 IL-6 水平。
T3S1068	Oxyresveratrol trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene	Tyrosinase; Autophagy; HSV	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Oxyresveratrol (trans-Oxyresveratrol) 是非竞争性酪氨酸酶抑制剂，对蘑菇酪氨酸酶的 IC50值为 1.2 µM。它抑制HSV-1，HSV-2和水痘带状疱疹病毒，具有神经保护作用。它是天然抗氧化剂和自由基清除剂。
T1558	Resveratrol 白藜芦醇,trans-Resveratrol,SRT 501	Apoptosis; Mitophagy; IκB/IKK; Lipoxygenase; Sirtuin; COX; NADPH; DNA/RNA Synthesis; Nrf2; Antibacterial; Antibiotic; Autophagy; Antifungal	Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience; NF-κB
	Resveratrol (SRT 501) 属于多酚类天然产物，是一种植物抗毒素，具有抗氧化和化学预防活性。Resveratrol 的靶点广泛，包括 COX、SIRT、LOC 等。Resveratrol 可以诱导细胞自噬和凋亡。

天然产物

Cat.No: T3363

Synonym: 蒜黎芦碱,Iervin,11-Ketocyclopamine,Jerwiny

Target: Hedgehog/Smoothened, Smo

Cat.No: TN1057

Synonym: 藜芦托素,Veratramine 3-glycoside,Veratramine-beta-D-glucoside

Target: Platelet aggregation

Cat.No: TN2343

Synonym: Jervin-3-glucoside,O-beta-D-Glucopyranosyljervine,假白藜芦碱

Target: Platelet aggregation

Cat.No: T2173

Target: Sodium Channel

Cat.No: T82262

Cat.No: T82009

Cat.No: T39854

3,4-Dimethoxyphenylacetic acid

Cat.No: T0568

Synonym: Homoveratrumic acid,homoveratric acid,高藜芦酸

Target: Others, Endogenous Metabolite

Cat.No: T3744

Synonym: Veratrumenoic acid,藜芦酸,3,4-Dimethoxybenzoic acid

Target: Reactive Oxygen Species, COX

Cat.No: T3S1068

Synonym: trans-Oxyresveratrol,2,3',4,5'-tetrahydroxystilbene,氧化白藜芦醇,Tetrahydroxystilbene

Target: Tyrosinase, Autophagy, HSV

Cat.No: T1558

Synonym: 白藜芦醇,trans-Resveratrol,SRT 501

Target: Apoptosis, Mitophagy, IκB/IKK, Lipoxygenase, Sirtuin, COX, NADPH, DNA/RNA Synthesis, Nrf2, Antibacterial, Antibiotic, Autophagy, Antifungal

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