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Search Results for " psoralen "

5

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0179	PAP-1 5-(4-Phenoxybutoxy)psoralen	Potassium Channel	Membrane transporter/Ion channel
	PAP-1 (5-(4-Phenoxybutoxy)psoralen) 是口服活性的Kv1.3选择性阻滞剂 (EC50=2 nM)。它依赖性阻止 Kv1.3，并优先与通道的 C 型失活状态结合来发挥作用。
T10110	3-CPs 3-Carbethoxypsoralen,3-Ethoxycarbonylpsoralen	Antibiotic	Microbiology/Virology
	3-CPs (3-Carbethoxypsoralen) 是一种博来霉素诱导的小鼠肺纤维化血清型荚膜多糖，属于补骨脂，可干扰抗体介导的细菌杀伤作用。3-CPs 可延缓博来霉素诱导的小鼠肺纤维化，可用于研究气道炎和哮喘。
T19193	Amotosalen hydrochloride S-59	Others	Others
	Amotosalen hydrochloride (S-59) is a light-activated, RNA-, DNA-crosslinking psoralen compound and is used to neutralize pathogens.
T60896	HER2-IN-11
	HER2-IN-11 是能够诱导细胞凋亡的补骨脂素衍生物。HER2-IN-11 显示出光激活细胞毒性，并且具有抗乳腺癌活性。
T60572	HER2-IN-10
	HER2-IN-10 是一种可以诱导细胞凋亡的补骨脂素衍生物。HER2-IN-10 显示出抗乳腺癌活性和光激活细胞毒性

化合物

Cat.No: TQ0179

Synonym: 5-(4-Phenoxybutoxy)psoralen

Target: Potassium Channel

Cat.No: T10110

Synonym: 3-Carbethoxypsoralen,3-Ethoxycarbonylpsoralen

Target: Antibiotic

Amotosalen hydrochloride

Cat.No: T19193

Synonym: S-59

Target: Others

Cat.No: T60896

Cat.No: T60572

Cat. No.	Product Name	Target	Signaling Pathways
T2942	Psoralen Ficusin,Furocoumarin,补骨脂素,psoralene	Apoptosis; Influenza Virus; HIV Protease; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Proteases/Proteasome
	Psoralen (Ficusin) 是从补骨脂种子中提取的一种香豆素。它具有如抗癌、抗氧化、抗抑郁、抗癌、抗菌、抗病毒等多种生物学特性。
T4S1659	Xanthotoxol 8-Hydroxypsoralen,8-Hydroxyfuranocoumarin,Psoralen,花椒毒酚,8-Hydroxypsoralene	Reactive Oxygen Species; 5-HT Receptor; Endogenous Metabolite	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Xanthotoxol (Psoralen) 是一种具有生物活性的线性呋喃香豆素，具有很强的抗炎、抗氧化、5-HT 拮抗和神经保护作用等药理活性。
T40636	8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen
	8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen is a coumarin compound present in Heracleum pyrenaicum Lam.
TN3267	8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen	Others	Others
	8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3267，CAS号为 144398-34-5。
TN3266	8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen	Others	Others
	8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3266，CAS号为 151121-39-0。
TN6298	8-[(6,7-Dihydroxy-3,7-dimethyloct-2-en-1-yl)oxy]psoralen
	8-[(6,7-Dihydroxy-3,7-dimethyloct-2-en-1-yl)oxy]psoralen 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6298，CAS号为 889112-17-8。
TN1008	Psoralenoside	CaMK; Calcium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience
	Psoralenoside 是源于补骨脂中的苯并呋喃苷，具有抗肿瘤、抗菌、促进成骨细胞增殖和雌激素样活性。它对组胺 H1、钙调素和电压门控 l 型钙通道具有较高的亲和力。
TN1148	Isopsoralenoside	Estrogen Receptor/ERR; Estrogen/progestogen Receptor; Antibacterial	Endocrinology/Hormones; Microbiology/Virology
	Isopsoralenoside 是补骨脂多糖中的一种苯并呋喃苷。它在消化道内容物中可迅速代谢为补骨脂素。它具有雌激素样活性、促进成骨细胞增殖活性、抗肿瘤活性和抗菌活性。
TN1343	8-Geranyloxypsoralen 8-香叶草氧基补骨脂素	Anti-infection; P450; BACE	Metabolism; Microbiology/Virology; Neuroscience
	8-Geranyloxypsoralen 是一种呋喃香豆素，分离自葡萄柚，是 P450 3A4 的有效抑制剂(IC50:3.93 μM)。
T40859	5-Hydroxy-8-methoxypsoralen 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen
	5-Hydroxy-8-methoxypsoralen (5-Hydroxyxanthotoxin) is a metabolite derived from Xanthotoxin, which acts as a potent tricyclic furocoumarin suicide inhibitor of CYP (cytochrome P-450). It is employed as an agent for the treatment of psoriasis, eczema, vitiligo, and certain cutaneous Lymphomas, in combination with phototherapy involving exposure to sunlight.
TN3281	8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen	Others	Others
	8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen是一种天然产物，属于豆科补骨脂属，其产品编号为 TN3281，CAS号为 425680-98-4。8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen可用作对照参考。
TN2425	5,8-Dihydroxypsoralen	Others	Others
	5,8-Dihydroxypsoralen is a natural product from Pueraria lobata (Willd.) Ohwi
T2143	Bergapten 5-Methoxypsoralen,佛手柑内酯,香柑内酯	P450; Autophagy	Autophagy; Metabolism
	Bergapten (5-Methoxypsoralen) 是白芷中的一种香豆素，也是一种补骨脂素，可抑制细胞复制。
T32649	Leptophylloside Isorutarin
	Leptophylloside is a kind of psoralen.
T4558	Trioxsalen 三甲沙林,Trimethylpsoralen,Trioxysalen,Trisoralen	DNA Alkylator/Crosslinker; DHFR	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	Trioxsalen (Trioxysalen) 是一种呋喃香豆素和补骨脂素衍生物，与 UV-A 一起用于光疗治疗白癜风和手部湿疹。它是一种光化学 DNA 交联剂，可用于激光激活定位的基因组链间交联可视化。

天然产物

Cat.No: T2942

Synonym: Ficusin,Furocoumarin,补骨脂素,psoralene

Target: Apoptosis, Influenza Virus, HIV Protease, DNA/RNA Synthesis

Cat.No: T4S1659

Synonym: 8-Hydroxypsoralen,8-Hydroxyfuranocoumarin,Psoralen,花椒毒酚,8-Hydroxypsoralene

Target: Reactive Oxygen Species, 5-HT Receptor, Endogenous Metabolite

8-(3-Ethoxy-2-hydroxy-3-methylbutyloxy)psoralen

Cat.No: T40636

8-(7-Hydroxy-3,7-dimethyl-2,5-octadienyloxy)psoralen

Cat.No: TN3267

Target: Others

8-(6-Hydroperoxy-3,7-dimethyl-2,7-octadienyloxy)psoralen

Cat.No: TN3266

Target: Others

8-[(6,7-Dihydroxy-3,7-dimethyloct-2-en-1-yl)oxy]psoralen

Cat.No: TN6298

Psoralenoside

Cat.No: TN1008

Target: CaMK, Calcium Channel, Histamine Receptor

Isopsoralenoside

Cat.No: TN1148

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Antibacterial

8-Geranyloxypsoralen

Cat.No: TN1343

Synonym: 8-香叶草氧基补骨脂素

Target: Anti-infection, P450, BACE

5-Hydroxy-8-methoxypsoralen

Cat.No: T40859

Synonym: 5-Hydroxyxanthotoxin,5-Hydroxy-8-methoxypsoralen

8-Hydroxy-5-O-beta-D-glucopyranosylpsoralen

Cat.No: TN3281

Target: Others

5,8-Dihydroxypsoralen

Cat.No: TN2425

Target: Others

Cat.No: T2143

Synonym: 5-Methoxypsoralen,佛手柑内酯,香柑内酯

Target: P450, Autophagy

Leptophylloside

Cat.No: T32649

Synonym: Isorutarin

Cat.No: T4558

Synonym: 三甲沙林,Trimethylpsoralen,Trioxysalen,Trisoralen

Target: DNA Alkylator/Crosslinker, DHFR

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