42
5
9
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T2313 |
MPI-0479605
|
Apoptosis; Kinesin | Apoptosis; Cytoskeletal Signaling |
MPI0479605 是一种选择性的,ATP 竞争性的 Mps1抑制剂,IC50值为 1.8 nM。 | |||
T68541 |
MPI8
|
||
MPI8 is a SARS-CoV-2 Protease inhibitor (IC50 = 105 nM). | |||
T68429 |
MPI3
|
||
MPI3 is a SARS-CoV-2 Protease inhibitor (IC50 = 8.5 nM). | |||
T16129 |
MPI_5a
|
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
MPI_5a 是高效的 HDAC6选择性抑制剂,IC50=36 nM,对其他 HDAC 酶几乎无抑制作用。MPI_5a 抑制细胞内酰基微管蛋白积累, IC50为 210 nM。 | |||
T79613 |
MPI60
|
SARS-CoV | Microbiology/Virology |
MPI60是高效的SARS-CoV-2 MPro抑制剂,展现出高抗病毒效力、低细胞毒性以及优良的体外代谢稳定性,适用于SARS-CoV-2的研究工作。 | |||
T21769L |
β-Pompilidotoxin Acetate
β-Pompilidotoxin Acetate(216064-36-7 Free base) |
Sodium Channel | Membrane transporter/Ion channel |
β-Pompilidotoxin Acetate 是一种黄蜂毒肽。 它可以减缓钠通道的失活并增加细胞中的稳态钠电流。 | |||
T0296 |
Pempidine
潘必定,1,2,2,6,6-Pentamethylpiperidine,Perolysen,Pyrilene |
Others; AChR | Neuroscience; Others |
Pempidine (1,2,2,6,6-Pentamethylpiperidine) 是一种口服具有活力的神经节阻断试剂,用于研究高血压。 | |||
T23008L |
MMPIP hydrochloride
MMPIP hydrochloride (479077-02-6 Free base) |
GluR | Neuroscience |
MMPIP hydrochloride 是变构 mGluR7 的选择性拮抗剂。 MMPIP hydrochloride 可用于研究 mGluR7 对中枢神经系统功能的作用。 | |||
T6387 |
Ampiroxicam
CP 65703,Flucam,安吡昔康 |
COX | Immunology/Inflammation; Neuroscience |
Ampiroxicam (Flucam) 是一种非选择性的环氧化酶抑制剂,有抗炎活性。 | |||
T40867 |
Simpinicline
OC-02 |
AChE | Neuroscience |
Simpinicline (OC-02)(OC-02)是一种高选择性烟碱乙酰胆碱受体(nAChR)激动剂,可激活三叉神经副交感神经通路,可用于治疗干眼症。 | |||
T6386 |
Ampicillin sodium
氨苄西林钠,Domicillin,D-(-)-α-Aminobenzylpenicillin sodium salt,Penialmen,Citteral |
Antibacterial; Antibiotic | Microbiology/Virology |
Ampicillin sodium (Domicillin) 是Ampicillin 的钠盐形式,是Ampicillin 的广谱半合成衍生物。它通过与青霉素结合蛋白结合来抑制细菌细胞壁的合成,从而抑制肽聚糖的合成,肽聚糖是细菌细胞壁的关键成分。 | |||
T0814L1 |
L-(+)-Ampicillin
Ampicillin,L-Ampicillin |
||
L-(+)-Ampicillin is an isomer of Ampicillin. Ampicillin is a β-lactam antibiotic used for treating bacterial infections. | |||
T76951 | Zampilimab | ||
Zampilimab (UCB-7858),一种转谷氨酰胺酶 2 (TG2) 单克隆抗体,具有肾移植潜在应用。 | |||
T71183 |
Simpinicline citrate
|
||
Simpinicline citrate is a nicotinic acetylcholine receptor (nAChR) agonist. | |||
T70961 |
Dmb-rifampicin
|
||
Dmb-rifampicin is an inhibitor of nucleic acid polymerases. | |||
T35706 |
25-Desacetyl Rifampicin
|
||
25-Desacetyl rifampicin is a major active metabolite of the rifamycin antibiotic rifampicin .125-Desacetyl rifampicin is active againstM. smegmatis(MIC99= 2.66 μM). 1.Kigondu, E.M., Njoroge, M., Singh, K., et al.Synthesis and synergistic antimycobacterial screening of chlorpromazine and its metabolitesMed. Chem. Commun.5502-506(2014) | |||
TMIH-0494 |
Rifampicin-d3
|
||
Rifampicin-d3 是 Rifampicin 的氘代化合物。Rifampicin 的 CAS 号为 13292-46-1。Rifampicin是广谱抗生素,可抵抗细菌病原体以及具有抗流感病毒活性。 | |||
TMIH-0496 |
Rifampicin-d8
|
||
Rifampicin-d8 是 Rifampicin 的氘代化合物。Rifampicin 的 CAS 号为 13292-46-1。Rifampicin是广谱抗生素,可抵抗细菌病原体以及具有抗流感病毒活性。 | |||
T24839 |
Stampidine
HI-113,HI 113,HI113 |
||
Stampidine can prevent the sexual transmission of HIV-1. It exhibited remarkable subnanomolar to low nanomolar in vitro antiretroviral potency against nucleoside reverse transcriptase inhibitor-resistant primary clinical HIV isolates, non-nucleoside RT-re | |||
T39771 |
nAChR agonist CMPI hydrochloride
|
||
nAChR agonist CMPI hydrochloride is a potent and selective positive allosteric modulator (PAM) of nAChR containing a α4:α4 subunit interface. nAChR agonist CMPI hydrochloride enhances the response of (α4) 3 (β2) 2 nAChR to ACh (10 μM) with an EC 50 of 0.26 μM. nAChR agonist CMPI hydrochloride has potential for the research of nicotine dependence and many neuropsychiatric conditions associated with decreased brain cholinergic activity. | |||
T15734 |
Lenampicillin hydrochloride
盐酸仑氨苄西林,KBT 1585 hydrochloride |
Antibacterial | Microbiology/Virology |
Lenampicillin hydrochloride is an orally active prodrug of Ampicillin. Lenampicillin hydrochloride is an effective beta-lactam antibacterial agent that inhibits bacterial penicillin-binding proteins. It is applied in the investigation of suppurative skin | |||
T25659 |
Lenampicillin
Lenampicilina |
||
Lenampicillin is a Beta-lactam antibacterial agent. | |||
T33304 |
Metampicillin
|
||
Metampicillin is a semi-synthetic penicillin. | |||
T80704 |
α-Pompilidotoxin
α-PMTX |
||
α-Pompilidotoxin (α-PMTX) 是从 Anoplius samariensis 的毒液中分离的一种神经毒素。它能剂量依赖性地增强兴奋性突触后电流(EPSCs),并且这种增强作用是可逆的。α-Pompilidotoxin 在神经科学研究中被作为实验工具广泛应用。 | |||
T82899 |
Bempikibart
ADX-914 |
||
Bempikibart (ADX-914)为一种针对IL-7Rα的人源化单克隆抗体,适用于炎症相关的研究领域。 | |||
T10448 |
Bacampicillin
|
Others | Others |
Bacampicillin is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin. | |||
T34776L |
Talampicillin hydrochloride
BRL 8988 |
||
Talampicillin hydrochloride is a biochemical. | |||
T34122 |
Prampine
|
||
Prampine is a biochemical. | |||
T23008 |
MMPIP
MMPIP hydrochloride |
Others | Others |
allosteric mGlu7-selective receptor antagonist | |||
T34082 |
Pivampicillin Hydrochloride
Devonium,Alphacilina,Sanguicillin,Centurina,Alphacillin |
||
Piampicillin Hydrochloride is a Hydrochloride form of an oral active ampicillin new spray with antimicrobial activity. | |||
T34776 |
Talampicillin
|
||
Talampicillin is an ester of Ampicillin. It is hydrolyzed upon absorption to release ampicillin. It is well absorbed from the gastrointestinal tract resulting in a greater bioavailability of ampicillin than can be achieved with equivalent doses of ampicil | |||
TMIH-0495 |
Rifampicin-d4
|
||
Rifampicin-d4 是 Rifampicin 的氘代化合物。 | |||
T10448L |
Bacampicillin hydrochloride
|
Others | Others |
Bacampicillin hydrochloride is an improved oral bioavailability penicillin antibiotic which is a prodrug of ampicillin. | |||
T37293 | CMPI hydrochloride | ||
Potent positive allosteric modulator of α4β2 nAChRs (EC50 values are 20 and 18 nM for rat and human, respectively). Selective for hα4β2 over hα3β2, hα3β4 and hα7. Inhibits (α4)2(β2)3, muscle-type and Torpedo nAChRs (IC50 values are 0.5, 0.7 and 0.2 μM, respectively), but not (α4)3(β2)2 receptors. Exhibits ability to photoincorporate into aliphatic and nucleophilic amino acid side chains. Hamouda (2016) Photolabeling a nicotinic acetylcholine receptor (nAChR) with an (α4)3(β2)2 nAChR-selective p... | |||
T75797 |
β-Pompilidotoxin TFA
|
||
β-Pompilidotoxin TFA (β-PMTX TFA) 是能够减缓钠通道 (sodium channel) 的失活并增加细胞中的稳态钠电流的黄蜂毒液。 | |||
T20829 |
Pivampicillin
|
||
Pivampicillin, a pivalate ester analog of Ampicillin, is used to treat chronic obstructive pulmonary disease (COPD) in children and young adults. | |||
T28546 |
RMPI-8226-38
RMPI 8226-38,RMPI-8226 38,RMPI8226-38,RMPI8226 38 |
||
RMPI-8226-38 is an irreversible inhibitor of USP7 with IC50 value of 22 uM against RMPI-8226. | |||
T38800 |
MMPI-1154
|
||
MMPI-1154 is a highly promising imidazole-carboxylic acid (ICA) MMP-2 inhibitor (IC 50 = 6.6 μM) with excellent cardio-cytoprotective properties. It is specifically designed for the study of acute myocardial infarction. Additionally, MMPI-1154 exhibits significant inhibitory effects on MMP-13, MMP-1, and MMP-9 activities with IC 50 values of 1.8 μM, 10 μM, and 13 μM, respectively. | |||
T30042 |
Ampicillinoic acid
|
||
Ampicillinoic acid is a hydrolysis (ring-open) product of ampicillin. | |||
T68992 |
Pempidine HCl
|
||
Pempidine HCl is a nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more specific drugs. | |||
T69120 |
Pempidine tartrate
|
||
Pempidine tartrate is a nicotinic antagonist most commonly used as an experimental tool. It has been used as a ganglionic blocker in the treatment of hypertension but has largely been supplanted for that purpose by more specific drugs. | |||
T16118 |
MLS0315771
|
Others | Others |
MLS0315771 是来源于磷酸甘露糖异构酶的竞争性抑制剂, 其 IC50值为~1 μM,Ki=为 1.4 μM。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T0814L |
Ampicillin
Amcill,D-(-)-α-Aminobenzylpenicillin,Aminobenzylpenicillin,氨苄青霉素,Ampicillin acid |
Antibacterial; Antibiotic | Microbiology/Virology |
Ampicillin (Aminobenzylpenicillin) 属于 β-内酰胺类抗生素,是一种半合成的青霉素。Ampicillin 具有杀菌活性,对各种革兰氏阳性细菌和革兰氏阴性细菌均有抑制活性。 | |||
T5776 |
pimpinellin
|
Apoptosis; Anti-infection | Apoptosis; Microbiology/Virology |
Pimpinellin 是贯众的一种成分,可通过诱导肿瘤细胞凋亡抑制肿瘤细胞的生长,可作为具有 GABA 受体活性的蛋白质的拮抗剂。 | |||
T0814 |
Ampicillin Trihydrate
NCI-C56086,氨苄青霉素三水合物 |
Antibacterial; Antibiotic | Microbiology/Virology |
Ampicillin Trihydrate (NCI-C56086) 是一种 β-内酰胺类广谱抗生素,可对抗多种革兰氏阳性和革兰氏阴性细菌。 | |||
T0681 |
Rifampicin
Rifamycin AMP,利福平,Rimactane,Rifampin |
Influenza Virus; DNA/RNA Synthesis; Antibacterial; Antibiotic; Antifection | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology |
Rifampicin (Rifamycin AMP) 是广谱抗生素,可抵抗细菌病原体以及具有抗流感病毒活性。 | |||
T4593 |
ISOPIMPINELLIN
5,8-Dimethoxypsoralen,异茴芹内酯,4,9-Dimethoxypsoralen |
Antiviral; DNA/RNA Synthesis; Parasite | Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; Microbiology/Virology |
Isopimpinellin (4,9-Dimethoxypsoralen) 是从 Pimpinella saxifrage 根部分离得到的一种天然产物,具有抗病毒和抗利什曼病活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-00767 |
SLPI Protein, Human, Recombinant (hFc)
WFDC4,HUSI,SLPI,WAP4,MPI,BLPI,ALK1,HUSI-1,ALP |
Human | HEK293 Cells |
Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation of the response to LPS (lipopolysaccharide) stimulation. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions. SLPI Protein, Human, Recombinant (hFc) is express... | |||
TMPK-00924 |
SLPI Protein, Mouse, Recombinant (hFc)
WAP4,BLPI,SLPI,HUSI-1,HUSI,MPI,ALP,WFDC4,ALK1 |
Mouse | HEK293 Cells |
Elafin and SLPI (secretory leucocyte protease inhibitor) have multiple important roles both in normal homoeostasis and at sites of inflammation. These include antiprotease and antimicrobial activity as well as modulation of the response to LPS (lipopolysaccharide) stimulation. Elafin and SLPI are members of larger families of proteins secreted predominantly at mucosal sites, and have been shown to be modulated in multiple pathological conditions. SLPI Protein, Mouse, Recombinant (hFc) is express... | |||
TMPY-01024 |
LIMPII/SR-B2 Protein, Human, Recombinant (His & hFc)
LGP85,SR-BII,AMRF,EPM4,LIMPII,LIMP-2,HLGP85,CD36L2,... |
Human | HEK293 Cells |
LIMPII/SR-B2 Protein, Human, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 74.4 kDa and the accession number is A0A024RDG6. | |||
TMPH-03324 |
LIMPII/SR-B2 Protein, Rat, Recombinant (His & Myc)
|
Rat | E. coli |
Acts as a lysosomal receptor for glucosylceramidase (GBA) targeting. LIMPII/SR-B2 Protein, Rat, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.7 kDa and the accession number is P27615. | |||
TMPY-03886 |
MPIF-1/CCL23 Protein, Human, Recombinant
SCYA23,CKb8,Ckb-8,MPIF-1,MPIF1,chemokine (... |
Human | E. coli |
MPIF-1/CCL23 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 11.4 kDa and the accession number is P55773-1. | |||
TMPJ-00299 |
LIMPII/SR-B2 Protein, Mouse, Recombinant (hFc)
LIMP II,Lysosome membrane protein II,SCARB2,85 kDa lysosomal... |
Mouse | HEK293 Cells |
Lysosome membrane protein II (LIMPII),also known as SCARB2, is a type III multi-pass membrane glycoprotein that is located primarily in limiting membranes of lysosomes and endosomes on all tissues and cell types so far examined. Earlier studies in mice and rat suggested that this protein may participate in membrane transportation and the reorganization of endosomal/lysosomal compartment. The protein deficiency in mice was reported to impair cell membrane transport processes and cause pelvic junc... | |||
TMPY-01434 |
LIMPII/SR-B2 Protein, Mouse, Recombinant (His)
LIMP-2,MLGP85,9330185J12Rik,LGP85,scavenger receptor class B... |
Mouse | HEK293 Cells |
LIMPII/SR-B2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47.8 kDa and the accession number is O35114. | |||
TMPY-00168 |
MPIF-1/CCL23 Protein, Human, Recombinant (His)
MIP3,MIP-3,Ckb-8-1,CK-BETA-8,Ckb-8,MPIF-1,MPI |
Human | P. pastoris (Yeast) |
MPIF-1/CCL23 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 9.9 kDa and the accession number is P55773.3. | |||
TMPY-05768 |
LIMPII/SR-B2 Protein, Human, Recombinant (hFc)
LIMP-2,AMRF,LGP85,CD36L2,LIMPII,HLGP85,SR-BII,scave... |
Human | HEK293 Cells |
LIMPII/SR-B2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 73.26 kDa and the accession number is Q14108. |