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95

抑制剂 & 化合物

27

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T9612	Antibacterial agent 27	Anti-infection	Microbiology/Virology
	Antibacterial agent 27 是抗菌化合物，显示出有效的抗念珠菌活性。
T38240	2,6-Dichlorodiphenylamine	Antibacterial	Microbiology/Virology
	2,6-Dichlorodiphenylamine 是双氯芬酸钠的一种结构类似物，显示出抗白色念珠菌活性。2,6-Dichlorodiphenylamine 是非选择性抗炎剂，为COX 的抑制剂，在 CHO 细胞中，对人 COX-1 和 COX-2 的IC50分别为 4 和 1.3 nM。
T27617	Inz-1	P450	Metabolism
	Inz-1 是一种有效的真菌特异性线粒体细胞色素 bc1 抑制剂，对酵母和人类的 IC50 分别为 8.092 和 45.320 μM。 Inz-1 可逆转氟康唑或其他三唑类抗真菌药对致病性真菌白色念珠菌的耐药性。
T50005	Sertaconazole	Antifungal	Microbiology/Virology
	Sertaconazole 是一种广谱抗真菌药。
T21678	3MB-PP1	PLK	Cell Cycle/Checkpoint
	3MB-PP1是嘌呤类似物，是一种 Polo 样激酶 1 (Plk1) 抑制剂。在表达类似物敏感的 Plk1 等位基因的细胞中，3MB-PP1 通过靶向 Plk1 阻断有丝分裂进程和细胞分裂。3MB-PP1 特异性抑制类似物敏感的 Ssn3 (Cdk8)。3MB-PP1 抑制 Leu93 突变 Zipper-interacting protein kinase(Leu93-ZIPK)，IC50为2 μM。3MB-PP1 可用于细胞分裂和白色念珠菌 (Candida albicans) 菌丝形成的研究。
T19717	Cyclo-L-Trp-L-Trp	Antifungal	Microbiology/Virology
	Cyclo-L-Trp-L-Trp 是一种广谱抗真菌剂。它还诱导组蛋白的高度乙酰化。
T6665	Sertaconazole nitrate FI-7045,Ginedermofix,FI7056,Ertaczo,硝酸舍他康唑	Antibiotic; Antifungal	Microbiology/Virology
	Sertaconazole nitrate (FI-7045) 是一种局部广谱抗真菌药，可用于治疗浅表皮肤和粘膜感染。
T60965	Anticandidal agent-1
	Anticandidal agent-1 (化合物 c2) 是有效的广谱抗念珠菌剂，可通过阻断菌丝伸长和丝化来抑制生物膜。Anticandidal agent-1 对光滑念珠菌和白念珠菌具有抗念珠菌活性，MIC50值分别为 13.51 和 8.65 μg/mL。
T17022	Tebuconazole	P450; Antifungal	Metabolism; Microbiology/Virology
	Tebuconazole 是一种农用唑类杀菌剂，可抑制 CYP51，对白色念珠菌 CYP51 和truncated Homo sapiens CYP51 的IC50分别为 0.9 和 1.3 μM。
T9602	Monocaprin	Anti-infection; Antibacterial	Microbiology/Virology
	Monocaprin 是癸酸的 1-单甘油酯，对包膜病毒、某些细菌和酵母白色念珠菌具有抗菌活性。
T124500	Alpha-Amyrone Urs-12-en-3-one,Alfa-Amyrenone	Others	Others
	Alpha-Amyrone (Alfa-Amyrenone) 是一种存在于植物 Inula candida (L.) Cass. subsp.地上部分的化合物，Alpha-Amyrone 是一种抗肿瘤化合物。
T67988	Embeconazole R 120758,CS 758	Antifungal	Microbiology/Virology
	Embeconazole (R 120758) 是一种三唑类抗真菌剂。Embeconazole 对念珠菌、曲霉菌、新型隐球菌等临床重要真菌具有较强的体外活性。
T16412	Oteseconazole VT-1161	P450; Antifungal	Metabolism; Microbiology/Virology
	Oteseconazole (VT-1161) 是一种口服有效的抗真菌剂，结合并抑制白色念球菌的 CYP51，Kd 值小于 39 nM。
T12732	Rezafungin 棘白菌素,SP-3025,CD101,Biafungin	Others; Antifungal	Microbiology/Virology; Others
	Rezafungin (SP-3025) 是一种长效的广谱棘皮菌素，对念珠菌、曲霉和肺孢子菌具有强效抗真菌活性。
T8536	Filastatin	Antifungal	Microbiology/Virology
	Filastatin 是一种长效的白色念珠菌丝状体抑制剂，具有强大的抗真菌作用。它抑制真菌与聚苯乙烯和人类细胞的粘附，从酵母到菌丝的形态转变，抑制菌丝特异性 HWP1 启动子。
T1799	Caspofungin Acetate 醋酸卡泊芬净,L 743873,Cancidas,MK 0991,L 743872	Antibiotic; Antifungal	Microbiology/Virology
	Caspofungin Acetate (MK 0991) 是一种抗真菌药，能够非竞争性地抑制 1,3-β-D 葡聚糖合酶的合成。
T2213	Terconazole Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,特康唑,曲康唑,R42470	Antifection; Antifungal	Microbiology/Virology
	Terconazole (Terazol 7) 是一种广谱抗真菌药物，用于研究阴道酵母菌感染。
T77686	1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone	Antifungal	Microbiology/Virology
	1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone 具有广谱的抗真菌活性，对白色念珠菌、黑曲霉、铜绿假单胞菌、金黄色葡萄球菌等具有抑制作用。
T7872	Monolaurin	Others	Others
	Monolaurin 是椰子油中的一种表面活性剂和乳化剂。它抑制葡萄球菌、链球菌、加德纳菌、念珠菌和嗜血杆菌的生长，并减少促炎细胞因子的产生。
T61502	Antifungal agent 32
	Antifungal agent 32 (compound 1a) is a highly effective antifungal compound. It displays strong inhibitory activity against Candida albicans filamentation and biofilm formation, as well as inhibiting the morphological switching of Candida albicans and its adherence to epithelial cells. This makes Antifungal agent 32 a valuable tool for research on Candida albicans infections [1].
T63755	Antitubercular agent-22
	Antitubercular agent-22 (Compound 2) 是有效的抗念珠菌和抗结核剂，能够作用于 Candida albicansMTCC 3017 (MIC: 2.34 μg/ml) 和 M. tuberculosis(H37Rv) (MIC: 2 μg/ml)。
T27023	Cispentacin
	Cispentacin is a β-amino acid and acts as a water-soluble antifungal antibiotic. Cispentacin is effective against Candida.
T27580	Icofungipen PLD 118,BAY 10-8888,PLD-118,PLD118,BAY 108888
	Icofungipen is an oral antifungals with active against Candida species.
T13787	N-563	Others	Others
	N-563 promotes resistance to Candida albicans infection in mice
T81494	PhD3
	PhD3是源自猴血白细胞的抗菌肽，具备针对细菌和（Candida albicans）的抗菌活性。
T81495	PhD2
	PhD2是一种源自猴血白细胞的抗菌肽，对细菌与(真菌)Candida albicans显示出抗生活性。
T81493	PhD4
	PhD4，源自猴血白细胞的抗菌肽，对细菌和真菌(Candida albicans)均显示活性。
T35297	ZD 0870 D 0870,D0870,ZD0870
	ZD 0870, used to treat infections caused by fluconazole-resistant candida albicans.
T28596	RO-09-4609 RO 09-4609,RO09-4609,RO 094609,RO-094609
	RO-09-4609 is a potent and selective inhibitor of Candida albicans N-myristoyltransferase (CaNmt).
T81496	PhD1
	PhD1是一种抗菌肽，源自猴血白细胞，对细菌和白色念珠菌(Candida albicans)具有抗菌活性。
T28051	MK 3118 MK3118,SCY078,SCY-078,MK-3118,SCY 078
	MK 3118, a glucan synthase inhibitor, is used potentially for the treatment of candida infection and aspergillosis.
T63525	Antitubercular agent-23
	Antitubercular agent-23 是有效的抗念珠菌及抗结核剂，能够作用于 Candida albicansMTCC 3017 (MIC: 1.1 μg/ml) 和 M. tuberculosis(H37Rv) (MIC: 1 μg/ml)。
T10334	Antifungal agent 2	Others	Others
	Antifungal agent 2 is a broad-spectrum fungal inhibitor that inhibits the growth of pertinent species of Cryptococcus, Candida, and Aspergillus at a concentration as low as 0.5 μg/mL.
T28815	SM21 perchlorate SM21,SM 21,SM-21
	SM21 is a highly potent antifungal agent (MIC = 0.2-1.6 µg/ml) with no toxic to various human cell lines or bacterial species in vitro and was active against Candida isolates that are resistant to existing antifungal agents.
T62098	Antifungal agent 28
	Antifungal agent 28 (化合物 18) 是一种选择性的、有效的抗真菌剂。Antifungal agent 28 可以破坏成熟念珠菌生物膜，能够抑制白念珠菌和非白念珠菌的致病性菌株，包括耐氟康唑菌株。Antifungal agent 28 对隐球菌和曲霉菌株也具有抑制作用。
T74831	Antifungal agent 51
	Antifungal agent 51 (5c) 具有强效的抗真菌活性，尤其是对白色念珠菌 FDC 151 、近平滑念珠菌 ATCC 22019 和热带假丝酵母 FDC 138，MIC 值小于 0.063 μg/mL，而对细胞的毒性较低，无致癌性。
T25342	Discobahamin A
	Discobahamin A is a bioactive peptide isolated from a new species of the Bahamian deep water marine sponge Discodermia. It is a growth of Candida albicans inhibitor.
T25343	Discobahamin B
	Discobahamin B is a bioactive peptide isolated from a new species of the Bahamian deep water marine sponge Discodermia. It is a growth of Candida albicans inhibitor.
T60291	β-Nor-lapachone
	β-Nor-lapachone 是一种光滑念珠菌 (Candida glabrata)的抗生物膜剂。β-Nor-lapachone 能刺激ROS 的产生，抑制光念珠菌的外排活性、粘附、生物膜形成和成熟生物膜代谢。β-Nor-lapachone 具有抗真菌活性。
T23955	Dactylfungin B
	Dactylfungins B is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.
T23954	Dactylfungin A
	Dactylfungins A is a novel antifungal antibiotic produced by Dactylaria Parvispora. The antibiotics were active against Candida pseudotropicalis and other fungi, with a MIC value of fewer than 10 micrograms/ml.
T64235	Antifungal agent 25
	Antifungal agent 25 是一种有效的、广谱的、体内具有代谢稳定性的抗真菌剂。Antifungal agent 25 对白色念珠菌和耐氟康唑的白色念珠菌都表现出抗真菌效果。
T30873	Chelator 1a Chelator1a,Chelator-1a	Antifungal	Microbiology/Virology
	Chelator 1a 具有抗真菌活性，抑制曲霉菌和念珠菌，可用于研究真菌感染和癌症。
T12732L	Rezafungin acetate Biafungin acetate,SP-3025 acetate,CD101 acetate	Others	Others
	Rezafungin acetate is an advanced echinocandin compound that exhibits broad-spectrum antifungal activity against Candida spp, Aspergillus spp, and Pneumocystis spp. This long-lasting next-generation medication showcases potent efficacy in combating fungal infections.
T76470	GVLSNVIGYLKKLGTGALNAVLKQ
	GVLSNVIGYLKKLGTGALNAVLKQ 是一种具有 24 个氨基酸的抗菌肽。 GVLSNVIGYLKKLGTGALNAVLKQ 可能形成 α 螺旋。GVLSNVIGYLKKLGTGALNAVLKQ (PGQ) 对革兰氏阴性菌、革兰氏阳性菌和酵母Candida albicans 具有抗性。
T69051	Aculeacin A
	Aculeacin A is used to study mutations that lead to antibiotic resistance in Saccharomyces cerevisiae, the inhibition of Candida albicans and the morphogenetic transformation of Candida albicans when treated. Aculeacin A is a lipopeptide that inhibits β-glucan synthesis in yeasts. The inhibition is due to the selective blockage of glucan synthase. Aculeacin A, an amphophilic antibiotic, inhibits the biosynthesis of β−glucan by selective blockage of β(1→3) glucan synthase.
T80629	2-Dodecanol
	2-Dodecanol有效抑制了C. albicans的菌丝形成和SIR2基因的表达。
T10311	Amphotericin X1 两性霉素 X1	Others	Others
	Amphotericin X1 is a derivative of Amphotericin B with good antifungal activity. Amphotericin X1 inhibits Candida albicans 33/079, Cryptococcus neoformans 451, C.parapsilosis 937A, Aspergillus niger 57A and A.fumigatus (MICs: 1 μg/mL, 1 μg/mL, 8 μg/mL, 2
T75712	Aminocandin
	Aminocandin (HMR 3270) 是一种水溶性的棘白菌素类抗真菌剂 (antifungal)，对 Aspergillus 和 Candidaspp. 具有良好的活性。
T80932	Tritrpticin
	Tritrpticin是一种来源于猪骨髓的抗菌肽，对Aspergillus fumigatus和Candida albicans表现出抗菌活性，其最小抑菌浓度（MIC）分别为250和1000 μg/ml。

化合物

Antibacterial agent 27

Cat.No: T9612

Target: Anti-infection

2,6-Dichlorodiphenylamine

Cat.No: T38240

Target: Antibacterial

Cat.No: T27617

Target: P450

Cat.No: T50005

Target: Antifungal

Cat.No: T21678

Target: PLK

Cyclo-L-Trp-L-Trp

Cat.No: T19717

Target: Antifungal

Sertaconazole nitrate

Cat.No: T6665

Synonym: FI-7045,Ginedermofix,FI7056,Ertaczo,硝酸舍他康唑

Target: Antibiotic, Antifungal

Anticandidal agent-1

Cat.No: T60965

Cat.No: T17022

Target: P450, Antifungal

Cat.No: T9602

Target: Anti-infection, Antibacterial

Cat.No: T124500

Synonym: Urs-12-en-3-one,Alfa-Amyrenone

Target: Others

Cat.No: T67988

Synonym: R 120758,CS 758

Target: Antifungal

Cat.No: T16412

Synonym: VT-1161

Target: P450, Antifungal

Cat.No: T12732

Synonym: 棘白菌素,SP-3025,CD101,Biafungin

Target: Others, Antifungal

Cat.No: T8536

Target: Antifungal

Caspofungin Acetate

Cat.No: T1799

Synonym: 醋酸卡泊芬净,L 743873,Cancidas,MK 0991,L 743872

Target: Antibiotic, Antifungal

Cat.No: T2213

Synonym: Gyno-Terazol,Terazol 3,Terazol 7,Triaconazole,特康唑,曲康唑,R42470

Target: Antifection, Antifungal

1-(4-AMinophenyl)-5,6-dihydro-3-(4-Morpholinyl)-2(1h)-pyridinone

Cat.No: T77686

Target: Antifungal

Cat.No: T7872

Target: Others

Antifungal agent 32

Cat.No: T61502

Antitubercular agent-22

Cat.No: T63755

Cat.No: T27023

Cat.No: T27580

Synonym: PLD 118,BAY 10-8888,PLD-118,PLD118,BAY 108888

Cat.No: T13787

Target: Others

Cat.No: T81494

Cat.No: T81495

Cat.No: T81493

Cat.No: T35297

Synonym: D 0870,D0870,ZD0870

Cat.No: T28596

Synonym: RO 09-4609,RO09-4609,RO 094609,RO-094609

Cat.No: T81496

Cat.No: T28051

Synonym: MK3118,SCY078,SCY-078,MK-3118,SCY 078

Antitubercular agent-23

Cat.No: T63525

Antifungal agent 2

Cat.No: T10334

Target: Others

SM21 perchlorate

Cat.No: T28815

Synonym: SM21,SM 21,SM-21

Antifungal agent 28

Cat.No: T62098

Antifungal agent 51

Cat.No: T74831

Cat.No: T25342

Cat.No: T25343

β-Nor-lapachone

Cat.No: T60291

Cat.No: T23955

Cat.No: T23954

Antifungal agent 25

Cat.No: T64235

Cat.No: T30873

Synonym: Chelator1a,Chelator-1a

Target: Antifungal

Rezafungin acetate

Cat.No: T12732L

Synonym: Biafungin acetate,SP-3025 acetate,CD101 acetate

Target: Others

GVLSNVIGYLKKLGTGALNAVLKQ

Cat.No: T76470

Cat.No: T69051

Cat.No: T80629

Amphotericin X1

Cat.No: T10311

Synonym: 两性霉素 X1

Target: Others

Cat.No: T75712

Cat.No: T80932

Cat. No.	Product Name	Target	Signaling Pathways
T1388	Fluconazole 氟康唑,UK-49858	Antibiotic; Antifection; Antifungal	Microbiology/Virology
	Fluconazole (UK-49858) 是一种对多种真菌具有活性的三唑类抗真菌剂，抑制 C. albicans 和 Candida kefyr 的 IC99为 0.20 μg/mL 至 0.39 μg/mL。
T6702	Terbinafine Terbinex,特比萘芬,SF 86-327,Lamisil,TDT 067	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Terbinafine (TDT 067) 是念珠菌属的角鲨烯环氧化酶有效的非竞争性抑制剂，Ki 值为 30 nM。它具有抗真菌感染活性。
T1411	Terbinafine hydrochloride KWD 2019,盐酸特比萘芬,Terbinafine HCl,TDT 067 hydrochloride	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Terbinafine hydrochloride (KWD 2019) 具有抗真菌感染活性。它是念珠菌属的角鲨烯环氧化酶的非竞争性抑制剂，Ki 值为 30 nM。它还对某些革兰氏阳性和革兰氏阴性细菌具有抗菌活性。
T14046	Anandamide 花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide	Cannabinoid Receptor; Endogenous Metabolite	GPCR/G Protein; Metabolism
	Anandamide ((5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide) 是一种免疫调节剂，通过大麻素受体 CB1 和 CB2 起作用，还通过中枢神经系统中的其他靶点起作用，如 GPR18/GPR55。
T9599	3,4,5-Trimethoxybenzaldehyde	Anti-infection; Antibacterial	Microbiology/Virology
	3,4,5-Trimethoxybenzaldehyde 是合成各种药物，特别是治疗细菌感染的甲氧苄啶的中间体，它有抗念珠菌功效并抑制粘附和生物膜。
T7029	Pseudolaric Acid C	Antifungal	Microbiology/Virology
	Pseudolaric Acid C 是一种从Pseudolarix kaempferiGorden 根皮部中分离的二萜酸，对白色念珠菌有较弱的抗真菌活性。
T23172	Polygodial Tadeonal,水蓼二醛	Antifungal	Microbiology/Virology
	Polygodial (Tadeonal) 是一种抗真菌增效剂和抗生素。它是一种倍半萜，具有抗痛觉过敏的作用。
T7910	4-Methoxybenzaldehyde 大茴香醛,Anisaldehyde,p-Anisaldehyde,Anisic aldehyde,4-Anisaldehyde,4-甲氧基苯甲醛,P-Methoxybenzaldehyde	Others; Endogenous Metabolite	Metabolism; Others
	4-Methoxybenzaldehyde (p-Anisaldehyde) 是一种天然存在的芳香酚类化合物，存在于许多植物物种中，包括辣根，茴香，八角茴香等。它是一种能够能的神经毒物，已经表现出致死亡率，吸引力和干扰宿主寻求的影响。
TN1651	Furanodiene	Apoptosis; PARP; Reactive Oxygen Species; Caspase; CDK; P-gp	Apoptosis; Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB; Proteases/Proteasome
	Furanodiene 是从姜黄中提取的一种萜类天然产物，可抑制外排转运蛋白Pgp 功能并降低 Pgp 蛋白水平。它通过抗血管生成和诱导ROS 产生，DNA 链断裂和细胞凋亡发挥抗癌作用。
T1678	Nystatin Stamycin,Fungicidin,制霉菌素,Nystavescent	Apoptosis; Antibiotic; Antifungal	Apoptosis; Microbiology/Virology
	Nystatin (Fungicidin) 是一种口服对酵母和支原体有效的多烯类抗真菌抗生素。它能增加质膜对包括氯离子等小单价离子的通透性。它可部分阻止 Oxaliplatin 诱导的脂筏聚集、DR4 和 DR5 聚集的胆固醇隔离试剂，减少细胞凋亡。
T0011	2-Phenylethanol 苯乙醇,Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol	Others; Virus Protease; Antibacterial; Antibiotic	Microbiology/Virology; Others
	2-Phenylethanol (Phenylethanol) 是从玫瑰、风笛、阿勒颇松、桔子花等多种物种中提取得到的一种无色液体。它有一种使人感到愉悦的气味，也是一种从真菌Candida albicans 产生的自体抗生素。它可用作香皂中的防腐剂，也用作香烟添加剂。
T25718	Lichesterol
	Lichesterol is extracted from polyene antibiotic-resistant Candida albicans.
TN2032	Pachypodol 霍香黃酮醇	Antifection	Microbiology/Virology
	Pachypodol has antibacterial and antifungal activities against Bacillus subtilis, Staphylococcus aureus, Staphylococcus faecalis, Echerichia coli, Pseudomonas aeruginosa, Candida albicans, Candida krusei and Candida galabrata.
TN1561	Dehydroglaucine	Antifection	Microbiology/Virology
	Dehydroglaucine is an acetylcholinesterase inhibitor, it shows antimicrobial activity against Staphylococcus aureus, Mycobacterium smegmatis, Candida albicans, and Aspergillus niger.
TN3400	Altechromone A	Antifection	Microbiology/Virology
	Altechromone A has antimicrobial activity, it is active against Bacillus subtilis, Escherichia coli, Pseudomonas fluorescens and Candida albicans with the MICs of 3.9, 3.9, 1.8, and 3.9 ug/ml, respectively.
TN2492	1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone	Others	Others
	1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone has moderate cytotoxicities against breast cancer (MDA-MB-435S) and lung adenocarcinoma (A549) cell lines, but lacks antifungal activity against Candida albicans.
T28379	PF-1163B PF1163B,(-)-PF1163B,PF 1163B
	PF-1163B is an antifungal agent form Penicillium sp. II. PF-1163B inhibits ergosterol (ERG) synthesis with IC50 value of 34 ng/ml. PF-1163B showed potent growth inhibitory activity against pathogenic fungal strain Candida albicans but did not show cytotox
T80335	Maximin H3
	Maximin H3，源自中华红腹蟾蜍Bombina maxima皮肤分泌，为一种抗菌肽。对Escherichia coli ATCC 25922、Staphylococcus aureus ATCC 2592、Bacillus pyocyaneus CMCC B1010 及Candida albicans ATCC 2002表现出显著抗性，其MIC值依次为20, 10, 20, 5 μg/ml。
T80349	Maximin H4
	Maximin H4是一种来自中华红腹蟾蜍(Bombina maxima)皮肤分泌物的抗菌肽，具有针对Escherichia coli ATCC25922、Staphylococcus aureus ATCC2592、Bacillus pyocyaneus CMCCB1010和Candida albicans ATCC2002的抗菌活性。其最小抑菌浓度(MIC)值依次为12、6、12、6 μg/ml。
T69225	Verrucarin J Muconomycin B
	Verrucarin J (Muconomycin B) 是Myrothecium 真菌家族的代谢物。Verrucarin J 诱导活性氧 (ROS) 生成和癌细胞系凋亡 (apoptosis)，例如 A549、HCT 116 和 SW-620 细胞。Verrucarin J 具有抗Candida albicans 和Mucor miehei 的活性。Verrucarin J 抑制沙粒病毒 Junin (JUNV) 产量，IC50为 1.2 ng/mL。
T75684	Monascorubrin
	Monascorubrin 是一种从红曲菌菌丝体中纯化获得的化合物，对枯草芽孢杆菌和拟假丝酵母显示出显著的抗生素活性。
T80334	Maximin H2
	Maximin H2，源自中华红腹蟾蜍(Bombina maxima)皮肤分泌物的抗菌肽，对Escherichia coli ATCC25922、Staphylococcus aureus ATCC2592、Bacillus pyocyaneus CMCCB1010及Candida albicans ATCC2002展示了明显的抗菌活性。其最小抑菌浓度(MIC)值依序为20、2、4、2 μg/ml。
T79008	Ys-II
	Ys-II (Compound 1)为源于丝兰(Yucca elephantipe)茎部的螺甾烷醇糖苷，具备针对白色念珠菌和新型隐球菌(Cryptococcus neoformans)的抗真菌效力(IC50分别为5和6μg/mL)。
T80332	Maximin H1
	Maximin H1是一种抗菌肽，由中华红腹蟾蜍(Bombina maxima)皮肤分泌物提取得到。该化合物对Escherichia coli ATCC 25922、Staphylococcus aureus ATCC 25923、Bacillus pyocyaneus CMCC B1010和Candida albicans ATCC 2002表现出抗菌活性，其最小抑菌浓度(MIC)值分别为9、4.5、9、4.5 μg/ml。
T79931	Mutanocyclin
	Mutanocyclin 作为一种效能显著的抗真菌剂，能够抑制白色念珠菌 (C. albicans) 的丝状形成，并下调 HWP1、ECE1、FLO8、TEC1 基因的 mRNA 表达水平。此外，Mutanocyclin 在体外小鼠模型中亦能有效抑制酵母形态的发展。
T8199	(±)-α-Bisabolol Bisabolol	Apoptosis; Antioxidant	Apoptosis; oxidation-reduction
	(±)-α-Bisabolol (Bisabolol) 是一种从洋甘菊、念珠菌树等植物精油中提取的倍半萜烯醇，是一种天然防腐剂，具有舒缓、抗刺激、抗炎、抗氧化和抗癌活性。(±)-α-Bisabolol 通过诱导细胞周期停滞、线粒体死亡和抑制 PI3K/Akt 信号通路来发挥作用，对 A549 NSC-LC 细胞产生抗癌作用 (IC50 = 15 μM)。(±)-α-Bisabolol 能强效诱导胶质瘤细胞凋亡。
TN4471	Lysicamine	IL Receptor; Antifection	Immunology/Inflammation; Microbiology/Virology
	Lysicamine shows significant antioxidant capacity in the ORAC(FL) assay and it is active against S. epidermidis and C. dubliniensis, with MIC values in the range 12.5-100 microg mL(-1). Lysicamine has antimicrobial and anti-inflammation activity, the mini

天然产物

Cat.No: T1388

Synonym: 氟康唑,UK-49858

Target: Antibiotic, Antifection, Antifungal

Cat.No: T6702

Synonym: Terbinex,特比萘芬,SF 86-327,Lamisil,TDT 067

Target: Antibacterial, Antibiotic, Antifungal

Terbinafine hydrochloride

Cat.No: T1411

Synonym: KWD 2019,盐酸特比萘芬,Terbinafine HCl,TDT 067 hydrochloride

Target: Antibacterial, Antibiotic, Antifungal

Cat.No: T14046

Synonym: 花生四烯酸乙醇胺,(5Z,8Z,11Z,14Z)-N-(2-Hydroxyethyl)icosa-5,8,11,14-tetraenamide

Target: Cannabinoid Receptor, Endogenous Metabolite

3,4,5-Trimethoxybenzaldehyde

Cat.No: T9599

Target: Anti-infection, Antibacterial

Pseudolaric Acid C

Cat.No: T7029

Target: Antifungal

Cat.No: T23172

Synonym: Tadeonal,水蓼二醛

Target: Antifungal

4-Methoxybenzaldehyde

Cat.No: T7910

Synonym: 大茴香醛,Anisaldehyde,p-Anisaldehyde,Anisic aldehyde,4-Anisaldehyde,4-甲氧基苯甲醛,P-Methoxybenzaldehyde

Target: Others, Endogenous Metabolite

Cat.No: TN1651

Target: Apoptosis, PARP, Reactive Oxygen Species, Caspase, CDK, P-gp

Cat.No: T1678

Synonym: Stamycin,Fungicidin,制霉菌素,Nystavescent

Target: Apoptosis, Antibiotic, Antifungal

2-Phenylethanol

Cat.No: T0011

Synonym: 苯乙醇,Phenethyl alcohol,2-Phenylethyl alcohol,Benzyl carbinol,Phenylethanol,Benzeneethanol

Target: Others, Virus Protease, Antibacterial, Antibiotic

Cat.No: T25718

Cat.No: TN2032

Synonym: 霍香黃酮醇

Target: Antifection

Dehydroglaucine

Cat.No: TN1561

Target: Antifection

Cat.No: TN3400

Target: Antifection

1,4,5,6-Tetrahydroxy-7,8-diprenylxanthone

Cat.No: TN2492

Target: Others

Cat.No: T28379

Synonym: PF1163B,(-)-PF1163B,PF 1163B

Cat.No: T80335

Cat.No: T80349

Cat.No: T69225

Synonym: Muconomycin B

Cat.No: T75684

Cat.No: T80334

Cat.No: T79008

Cat.No: T80332

Cat.No: T79931

(±)-α-Bisabolol

Cat.No: T8199

Synonym: Bisabolol

Target: Apoptosis, Antioxidant

Cat.No: TN4471

Target: IL Receptor, Antifection

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