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Search Results for " cac "

Targets Recommended: Amylin Receptor

32

抑制剂 & 化合物

6

天然产物

13

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TP2135L	cAC 253 acetate cAC 253 acetate (TP2135 Free base)	Amylin Receptor	GPCR/G Protein
	cAC 253 acetate (TP2135 Free base) 是 amylin 的拮抗剂，抑制 125I-adrenomedullin 结合，其IC50 值为 25 nM。
TP2135	cAC 253
	Amylin (AMY3) antagonist (IC50 = 0.3 μM). Protects neuronal cells from Aβ(1-42)-induced cytotoxicity in vitro. Brain penetrant. Improves spatial memory and reduces Aβ plaque number and total area in a mouse Alzheimer's disease model.
T77348	Butylboronicacid	Others	Others
	Butylboronicacid 是脲酶竞争性抑制剂，可作为单糖络合试剂。
T16808	Runcaciguat	Others; Guanylate cyclase	GPCR/G Protein; Others
	Runcaciguat 是一种可溶性鸟苷酸环化酶刺激剂。 Runcaciguat 与特异性部分腺苷 A1 受体激动剂相结合，可用于心血管和肾脏疾病的研究。
T12017	Methyllycaconitine citrate MLA	AChR	Neuroscience
	Methyllycaconitine citrate (MLA) 是一种可穿过血脑屏障的 α7 神经元烟碱乙酰胆碱受体（α7nAChR）拮抗剂，可用于研究神经系统疾病。
T39349	Vocacapsaicin hydrochloride CA-008 hydrochloride	TRP/TRPV Channel	Membrane transporter/Ion channel
	Vocacapsaicin hydrochloride (CA-008 hydrochloride) 是非阿片类 TRPV1 激动剂，是辣椒素的原料，可用于缓解疼痛。
T4330	CaCCinh-A01	Chloride channel	Membrane transporter/Ion channel
	CaCCinh-A01 是钙激活氯离子通道和TMEM16A 抑制剂，IC50值分别为 10 和 2.1 μM。
T10492	BD-AcAc 2 Ketone Ester	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	BD-AcAc 2 (Ketone Ester) 是一种酮单酯，是口服营养酮的来源。小鼠口服 BD-AcAc 2 后可提高血浆乙酰乙酸和β-羟基丁酸水平、血液钠离子、血糖水平和血肌酐水平。BD-AcAc 2 可以一定程度预防脓毒症小鼠的肌无力。BD-AcAc 2 显示出提高动物机体耐力和运动能力的潜力。BD-AcAc 2 还可用于研究糖尿病或帕金森病。
T77556	2-(4-Hydroxyphenylazo)benzoicacid
	2-(4-Hydroxyphenylazo)benzoicacid 是一种分光光度法探针，可显示与蛋白质结合时的吸收光谱变化，可与牛血清蛋白结合。
T34953	Triocacarcinone A Antibiotic DC 45 A(sub 2),DC-45 A(sub 2),Trioxacarcin A(sub 2)
	Triocacarcinone A is a biochemical.
T124926	Acacetin-7-glucuronide
	Acacetin-7-glucuronide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124926，CAS号为 38226-83-4。
T39348	Vocacapsaicin CA-008,Vocacapsaicin
	Vocacapsaicin (CA-008), a prodrug of Capsaicin and a first-in-class non-opioid TRPV1 agonist, offers significant and enduring pain relief.
T64956	8-Nonynoicacid
	8-Nonynoicacid 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64956。
T72748	(S,S)-BD-AcAc 2 (S,S)-Ketone Ester
	'(S,S)-BD-AcAc 2 ((S,S)-Ketone Ester) 作为 BD-AcAc 2 的 (S,S)-对映异构体，能够提高 AcAc 与丙酮水平，进而持续引发酮症并明显延缓中枢神经系统氧中毒(CNS-OT)所致的癫痫发作。'
T63362	Ulecaciclib
	Ulecaciclib 是口服具有活力的、能够透过血脑屏障的、表现出良好的药代动力学特征的细胞周期蛋白依赖激酶 (CDK) 抑制剂，对CDKs 的ki 为 0.62 μM (CDK2/Cyclin A)、3 nM (CDK6/Cyclin D3) 、0.2 nM (CDK4/Cyclin D1)和 0.63 μM (CDK7/Cyclin H)。
TP2283	parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]	Others	Others
	parathyroid hormone (7-34) [Homo sapiens] [Macaca fascicularis] is a peptide with the sequence H2N-LMHNLGKHLNSMERVEWLRKKLQDVHNF-OH, MW= 3474.03. Parathyroid hormone (PTH) is secreted by the chief cells of the parathyroid glands as a polypeptide containing
T79862	Tacaciclib	CDK	Cell Cycle/Checkpoint
	Tacaciclib为一CDK (cyclin-dependent kinases) 抑制剂，显示出抗肿瘤活性。
T123853	3,4-Di-o-galloylshikimicacid
	3,4-Di-o-galloylshikimicacid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T123853，CAS号为 95753-51-8。
T70234	Cacospongionolide B
	Cacospongionolide B is isolated from the sponge Fasciospongia cavernosa. The marine sponge natural product cacospongionolide B (1) is one of a class of compounds bearing a g-hydroxybutenolide which are known to inhibit multiple forms of secratory phospholipase A2,1 enzymes believed to initiate a cascade of biological events leading to inflammation.
T126409	5-0-Galloylshikimicacid
	5-0-Galloylshikimicacid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126409，CAS号为 110082-91-2。
T125671	Zizaens?ure; Zizanoicacid
	Zizaens?ure; Zizanoicacid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125671，CAS号为 16203-25-1。
T69433	Myrmicacin
	Myrmicacin is an inhibitor of mitotic progression after metaphase.
T31282	Decachloroquaterphenyl
	Decachloroquaterphenyl is a biochemical.
TNU0713	Ru(III) (acac)2(py-4-COOH)(Py-4-COO)
	Metal complex, bioreagent
T83297	5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT
	5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT 是带有荧光素 FAM 标记的寡核苷酸。
T21067	Decacyclene NSC 60676
	Decacyclene is a biochemical.
T65001	Benzoicacid-d5
	Benzoicacid-d5 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65001，CAS号为 1079-02-3。
T31281	Decachlorodiphenyl ether DECACHLORODIPHENYLOXIDE
	Decachlorodiphenyl ether is a biochemical.
T131567	Epicatechin (Epicatechol; Acacatechin; Kakaol)
	Epicatechin (Epicatechol; Acacatechin; Kakaol) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T131567。
T80417	Cacaoidin
	Cacaoidin是一种糖基化抗生素，从可可链霉菌菌株中分离得到，对革兰氏阳性病原菌(包括艰难梭菌)展示出较强的抗菌活性。
T66947	2-Amino-3,5-dibromobenzoicacid
	2-Amino-3,5-dibromobenzoicacid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66947，CAS号为 609-85-8。
T83298	5'6-FAM-GGUGAAAGACGAUGGACAATT,UUGUCCAUCGUCUUUCACCTT
	5'6-FAM-GGUGAAAGACGAUGGACAATT,UUGUCCAUCGUCUUUCACCTT 是一种由荧光分子5'6-FAM修饰的双链核糖核酸。其中，5'6-FAM实际为5-FAM与6-FAM的混合物，其激发和发射光谱的特征值分别为Ex/Em= 490 nm/520 nm。

化合物

cAC 253 acetate

Cat.No: TP2135L

Synonym: cAC 253 acetate (TP2135 Free base)

Target: Amylin Receptor

Cat.No: TP2135

Butylboronicacid

Cat.No: T77348

Target: Others

Cat.No: T16808

Target: Others, Guanylate cyclase

Methyllycaconitine citrate

Cat.No: T12017

Synonym: MLA

Target: AChR

Vocacapsaicin hydrochloride

Cat.No: T39349

Synonym: CA-008 hydrochloride

Target: TRP/TRPV Channel

Cat.No: T4330

Target: Chloride channel

Cat.No: T10492

Synonym: Ketone Ester

Target: Reactive Oxygen Species

2-(4-Hydroxyphenylazo)benzoicacid

Cat.No: T77556

Triocacarcinone A

Cat.No: T34953

Synonym: Antibiotic DC 45 A(sub 2),DC-45 A(sub 2),Trioxacarcin A(sub 2)

Acacetin-7-glucuronide

Cat.No: T124926

Cat.No: T39348

Synonym: CA-008,Vocacapsaicin

Cat.No: T64956

(S,S)-BD-AcAc 2

Cat.No: T72748

Synonym: (S,S)-Ketone Ester

Cat.No: T63362

parathyroid hormone (7-34) [Homo sapiens]/[Macaca fascicularis]

Cat.No: TP2283

Target: Others

Cat.No: T79862

Target: CDK

3,4-Di-o-galloylshikimicacid

Cat.No: T123853

Cacospongionolide B

Cat.No: T70234

5-0-Galloylshikimicacid

Cat.No: T126409

Zizaens?ure; Zizanoicacid

Cat.No: T125671

Cat.No: T69433

Decachloroquaterphenyl

Cat.No: T31282

Ru(III) (acac)2(py-4-COOH)(Py-4-COO)

Cat.No: TNU0713

5'6-FAM-UUCUCCGAACGUGUCACGUTT, ACGUGACACGUUCGGAGAATT

Cat.No: T83297

Cat.No: T21067

Synonym: NSC 60676

Cat.No: T65001

Decachlorodiphenyl ether

Cat.No: T31281

Synonym: DECACHLORODIPHENYLOXIDE

Epicatechin (Epicatechol; Acacatechin; Kakaol)

Cat.No: T131567

Cat.No: T80417

2-Amino-3,5-dibromobenzoicacid

Cat.No: T66947

5'6-FAM-GGUGAAAGACGAUGGACAATT,UUGUCCAUCGUCUUUCACCTT

Cat.No: T83298

Cat. No.	Product Name	Target	Signaling Pathways
T3981	Acacetin 4'-Methoxyapigenin,金合欢素,5,7-Dihydroxy-4'-methoxyflavone,Linarigenin	Apoptosis; IAP; COX; Autophagy	Apoptosis; Autophagy; Immunology/Inflammation; Neuroscience
	Acacetin (5,7-Dihydroxy-4'-methoxyflavone) 是一种来自狗舌草的口服有效类黄酮。它停在 PI3Kγ 的 ATP 结合口袋中，可导致癌细胞周期停滞，并诱导细胞凋亡和自噬。它有抗癌和抗炎活性，有潜力研究疼痛相关疾病。
TN7212	Acacetin-7-O-beta-D-galactopyranoside	Others	Others
	Acacetin-7-O-beta-D-galactopyranoside 是一种天然产物，存在于野菊花 Chrysanthemum indicum。
T83208	Acacetin 7-O-β-D-xylopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside
	Compound 10，即Acacetin 7-O-β-D-xylopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside，是一种从刺槐叶提取物中分离的黄酮苷。
T83209	Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside
	Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside (compound 8) 是一款从刺槐 (Leguminosae) 叶提取物中分离出的黄酮苷。
T83210	Acacetin 7-O-(6′′-O-α-L-rhamnopyranosyl-β-sophoroside)
	Acacetin 7-O-(6′′-O-α-L-rhamnopyranosyl-β-sophoroside)为从Valeriana jatamansi Jones中提取的黄酮苷类化合物。
T83207	Acacetin 7-O-β-sophoroside
	Acacetin 7-O-β-sophoroside，一种可从缬草根茎和根中分离得到的黄酮苷。

天然产物

Cat.No: T3981

Synonym: 4'-Methoxyapigenin,金合欢素,5,7-Dihydroxy-4'-methoxyflavone,Linarigenin

Target: Apoptosis, IAP, COX, Autophagy

Acacetin-7-O-beta-D-galactopyranoside

Cat.No: TN7212

Target: Others

Acacetin 7-O-β-D-xylopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside

Cat.No: T83208

Acacetin 7-O-β-D-glucuronopyranosyl-(1→2)[α-L-rhamnopyranosyl-(1→6)]-β-D-glucopyranoside

Cat.No: T83209

Acacetin 7-O-(6′′-O-α-L-rhamnopyranosyl-β-sophoroside)

Cat.No: T83210

Acacetin 7-O-β-sophoroside

Cat.No: T83207

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-01735	Carbonic Anhydrase 2 Protein, Human, Recombinant (His) HEL-S-282,CA-II,HEL-76,CAII,carbonic anhydrase II,CAC	Human	E. coli
	Carbonic Anhydrase 2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 30 kDa and the accession number is P00918.
TMPY-00054	Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc) Macaca fascicularis Cytωlovirus (CyCMV) (strain OT-...	CyCMV	HEK293 Cells
	Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 102.5 kDa and the accession number is E7DB34.
TMPH-00780	CACNA1C Protein, Guinea Pig, Recombinant (His) CACNA1C,CACNL1A1,CACH2,CAC	Guinea pig	E. coli
	Pore-forming, alpha-1C subunit of the voltage-gated calcium channel that gives rise to L-type calcium currents. Mediates influx of calcium ions into the cytoplasm, and thereby triggers calcium release from the sarcoplasm. Plays an important role in excitation-contraction coupling in the heart. Required for normal heart development and normal regulation of heart rhythm. Required for normal contraction of smooth muscle cells in blood vessels and in the intestine. Essential for normal blood pressur...
TMPH-02308	CACNA2D1 Protein, Human, Recombinant (His & SUMO) MHS3,Voltage-dependent calcium channel subunit alpha-2/delta...	Human	E. coli
	The alpha-2/delta subunit of voltage-dependent calcium channels regulates calcium current density and activation/inactivation kinetics of the calcium channel. Plays an important role in excitation-contraction coupling.
TMPH-02416	Albumin Protein, Macaca fascicularis, Recombinant (Yeast, His) ALB	Cynomolgus	P. pastoris (Yeast)
	Albumin Protein, Macaca fascicularis, Recombinant (Yeast, His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 68.0 kDa and the accession number is A2V9Z4.
TMPJ-00443	PCSK9 Protein, Macaca nemestrina, Recombinant (His) Proprotein Convertase Subtilisin/Kexin Type 9,PCSK9,PC9,Prop...	Macaca nemestrina	HEK293 Cells
	Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) is a secretory subtilase belonging to the proteinase K subfamily. PCSK9 is synthesized as a soluble zymogen that undergoes autocatalytic intramolecular processing in the ER , the pro domain and mature chain secrete together through noncovalent interactions. PCSK9 binds with low-density lipoprotein receptor (LDLR) and plays a major regulatory role in cholesterol homeostasis. PCSK9 also plays a role in the neural development.
TMPJ-00437	Fetuin A Protein, Macaca mulatta, Recombinant (His) Fetuin A,AHSG	Macaca mulatta	HEK293 Cells
	Alpha-2-HS-glycoprotein (AHSG) is a glycoprotein that is composed of two subunits, the A and B chains, belongs to the Cystatin family of proteases inhibitors. It is highly expressed in embryonic cells and adult hepatocytes, and is expressed to a lesser extent in monocytes/macrophages. AHSG is an important circulating inhibitor of calcification in vivo, and is downregulated during the acute-phase response. It is involved in several functions, such as endocytosis, brain development and the formati...
TMPJ-01424	IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His) IL-10RA,Interleukin-10 receptor subunit 1,IL-10R subunit 1,I...	Macaca Mulatta	HEK293 Cells
	Interleukin-10 Receptor alpha (IL-10 R alpha), also known as IL-10 R1, is transmembrane glycoprotein member of the class II cytokine receptor family. Interleukin-10 (IL10) is a key anti-inflammatory cytokine that is produced predominantly by leukocytes including T cells, B cells, monocytes, macrophages, and dendritic cells (DCs), as well as by some epithelial cells. The receptor for IL10 is a heterotetramer complex comprising two IL10Ra (also referred to as IL10R1) molecules and two IL10Rb (also...
TMPH-02791	c-Myc Protein, Mouse, Recombinant (GST) bHLHe39,MYC,Transcription factor p64,Class E basic helix-loo...	Mouse	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. c-Myc Protein, Mouse, Recombinant (GST) is...
TMPH-01720	c-Myc Protein, Human, Recombinant (His) Myc proto-oncogene protein,Transcription factor p64,Proto-on...	Human	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. c-Myc Protein, Human, Recombinant (His) is...
TMPH-01721	c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated BHLHE39,Class E basic helix-loop-helix protein 39,Transcript...	Human	E. coli
	Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. Binds to the VEGFA promoter, promoting VEGFA production and subsequent sprouting angiogenesis. Regulator of somatic reprogramming, controls self-renewal of embryonic stem cells. Functions with TAF6L to activate target gene expression through RNA polymerase II pause release. c-Myc Protein, Human, Recombinant (Avi & H...
TMPJ-01040	MAX Protein, Human, Recombinant (His) Protein Max,MAX,bHLHd4,Myc-Associated Factor X,Class D Basic...	Human	E. coli
	Myc-Associated Factor X (MAX) is a member of the basic helix-loop-helix leucine zipper (bHLHZ) family of transcription factors. It contains 1 basic helix-loop-helix (bHLH) domain. It is found in the brain, heart, and lung at high levels while lower levels are seen in the liver, kidney, and skeletal muscle. MAX forms a sequence-specific DNA-binding protein complex with MYC or MAD which recognizes the core sequence 5'-CAC[GA]TG-3'. The MYC-MAX complex is a transcriptional activator, whereas the MA...
TMPY-01000	BVES Protein, Human, Recombinant (GST) CARICK,LGMD2X,POP1,blood vessel epicardial substance,POPDC1,...	Human	E. coli
	Blood vessel epicardial substance (BVES), or POPDC1, is a tight junction-associated transmembrane protein that modulates epithelial-to-mesenchymal transition (EMT) via junctional signaling pathways. BVES plays a protective role both in ulcerative and infectious colitis and identify BVES as a critical protector of colonic mucosal integrity. The Popeye domain containing1, also called Bves (Popdc1/Bves), is a transmembrane protein that functions in muscle regeneration, heart rate regulation, hypoxi...

重组蛋白

Carbonic Anhydrase 2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01735

Species: Human

Expression System: E. coli

Macaca fascicularis Cytomegalovirus (CyCMV) (strain OT-1) glycoprotein B/gB Protein (hFc)

Cat.No: TMPY-00054

Species: CyCMV

Expression System: HEK293 Cells

CACNA1C Protein, Guinea Pig, Recombinant (His)

Cat.No: TMPH-00780

Species: Guinea pig

Expression System: E. coli

CACNA2D1 Protein, Human, Recombinant (His & SUMO)

Cat.No: TMPH-02308

Species: Human

Expression System: E. coli

Albumin Protein, Macaca fascicularis, Recombinant (Yeast, His)

Cat.No: TMPH-02416

Species: Cynomolgus

Expression System: P. pastoris (Yeast)

PCSK9 Protein, Macaca nemestrina, Recombinant (His)

Cat.No: TMPJ-00443

Species: Macaca nemestrina

Expression System: HEK293 Cells

Fetuin A Protein, Macaca mulatta, Recombinant (His)

Cat.No: TMPJ-00437

Species: Macaca mulatta

Expression System: HEK293 Cells

IL-10R alpha/IL-10RA Protein, Macaca mulatta, Recombinant (His)

Cat.No: TMPJ-01424

Species: Macaca Mulatta

Expression System: HEK293 Cells

c-Myc Protein, Mouse, Recombinant (GST)

Cat.No: TMPH-02791

Species: Mouse

Expression System: E. coli

c-Myc Protein, Human, Recombinant (His)

Cat.No: TMPH-01720

Species: Human

Expression System: E. coli

c-Myc Protein, Human, Recombinant (Avi & His & MBP), Biotinylated

Cat.No: TMPH-01721

Species: Human

Expression System: E. coli

MAX Protein, Human, Recombinant (His)

Cat.No: TMPJ-01040

Species: Human

Expression System: E. coli

BVES Protein, Human, Recombinant (GST)

Cat.No: TMPY-01000

Species: Human

Expression System: E. coli

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