461
9
136
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T14392 |
Azide-C2-SS-C2-biotin
|
Others | Others |
Azide-C2-SS-C2-biotin is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1]. | |||
T77570 |
AP-C2
|
PKA | Tyrosine Kinase/Adaptors |
AP-C2 是一种有效的小分子鸟苷 3',5'-环单磷酸 (cGMP) 依赖性蛋白激酶 II (cGKII) 抑制剂,对 cGKII 的 pIC50 为 5.2。 | |||
T8545 |
FEN1-IN-4
FEN1 Inhibitor C2 |
Others | Others |
FEN1-IN-4 (FEN1 Inhibitor C2) 是人类皮瓣内切核酸酶-1 (hFEN1) 抑制剂。 | |||
T40020 |
Pomalidomide-C2-acid
|
Others | Others |
Pomalidomide-C2-acid 是 PROTAC 的组成部分。 | |||
T40005 |
Pomalidomide-C2-COOH
|
Others | Others |
Pomalidomide-C2-COOH 是一种合成的 E3 连接酶配体-接头偶联物,它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。 | |||
T40012 |
Thalidomide-CH2CONH-C2-COOH
|
Others | Others |
Thalidomide-CH2CONH-C2-COOH 是一种合成的 E3 连接酶配体-接头偶联物,它结合了 PROTAC 技术中使用的基于Thalidomide 的CRBN 配体和接头。 | |||
T40006 |
Pomalidomide-CH2CONH-C2-COOH
|
Others | Others |
Pomalidomide-CH2CONH-C2-COOH 是一种合成的 E3 连接酶配体-接头偶联物,它结合了 PROTAC 技术中使用的基于 Pomalidomide 的 CRBN 配体和接头。 | |||
T17698 |
Bromo-PEG1-C2-azide
|
Others; PROTAC Linker | Others; PROTAC |
Bromo-PEG1-C2-azide 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T16486 |
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD
PF-05231023 |
FGFR; PROTAC Linker | Angiogenesis; PROTAC; Tyrosine Kinase/Adaptors |
Mal-amido-PEG2-C2-amido-Ph-C2-CO-AZD (PF-05231023) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 的合成分子。 | |||
T14797 |
Bromo-PEG3-C2-acid
溴代-三聚乙二醇-羧酸 |
PROTAC Linker | PROTAC |
Bromo-PEG3-C2-acid 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T7761 |
Pomalidomide-C2-NH2 hydrochloride
|
E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | PROTAC |
Pomalidomide-C2-NH2 hydrochloride 包含基于 Pomalidomide 的 cereblon 配体和 1 个 linker,是合成的 E3 连接酶配体-linker 偶联物。 | |||
T23409 |
FM4-64
SynaptoRedTM C2 |
Others | Others |
FM4-64 (SynaptoRedTM C2) 是一种苯乙烯类染料,染色效果稳定,但在在水溶液中基本不发荧光。FM4-64与质膜双层结合后不能被动扩散进入细胞内部,必须通过主动运输的方式进行跨膜运输。FM4-64 可用于研究胞吞胞吐和囊泡运输。 | |||
T18276 |
Mal-PEG2-C2-Boc
Mal-PEG2-T-Butyl Ester |
Others; PROTAC Linker | Others; PROTAC |
Mal-PEG2-C2-Boc (Mal-PEG2-T-Butyl Ester) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17719 |
Cbz-NH-PEG12-C2-acid
|
Others; PROTAC Linker | Others; PROTAC |
Cbz-NH-PEG12-C2-acid 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T17565 |
Biotin-PEG2-C2-iodoacetamide
Biotin-PEG2-iodoacetamide,生物素-二聚乙二醇-碘乙酰胺 |
Others; PROTAC Linker | Others; PROTAC |
Biotin-PEG2-C2-iodoacetamide (Biotin-PEG2-iodoacetamide) 是一种属于 PEG 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T18616 |
NH2-C2-NH-Boc
PROTAC Linker 22,N-叔丁氧羰基-1,2-乙二胺 |
Others; PROTAC Linker | Others; PROTAC |
NH2-C2-NH-Boc (PROTAC Linker 22) 是一种属于 alkyl chain 类的 PROTAC linker,可用于 PROTAC 分子的合成。 | |||
T40032 |
Pomalidomide-PEG4-C2-NH2 hydrochloride
|
PROTAC Linker | PROTAC |
Pomalidomide-PEG4-C2-NH2 hydrochloride 是 E3 连接酶配体和 linker 组成的 偶联物,包含基于 Pomalidomide 的 cereblon 配体和 4 个单元 PEG 的 linker,可用于 PROTAC 分子的合成。 | |||
T17916 |
Pomalidomide-PEG4-C2-NH2
Cereblon Ligand-Linker Conjugates 8,E3 Ligase Ligand-Linker Conjugates 22 |
Others; Ligand for E3 Ligase | Others; PROTAC |
Pomalidomide-PEG4-C2-NH2 (E3 Ligase Ligand-Linker Conjugates 22) 是一种合成的 E3 连接酶配体- linker 偶联物,用于 PROTAC 技术中。 | |||
T38279 |
C2-8
C2-8 |
||
C2-8 is an inhibitor of polyglutamine (polyQ) aggregation (IC50s = 25 and 0.05 μM for recombinant HDQ51 and in PC12 cells, respectively). It also inhibits polyQ aggregation in organotypic hippocampal slice cultures isolated from R6/2 transgenic mice and reduces neurodegeneration in a dose-dependent manner in a Drosophila model of Huntington's disease. C2-8 (100 and 200 mg/kg) reduces huntingtin aggregate size, reduces neuronal atrophy, and improves motor performance in a rotarod test in the R6/2... | |||
T40024 |
Pomalidomide-PEG1-CO2H
Pomalidomide-PEG1-C2-COOH |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Pomalidomide-PEG1-CO2H 是一种合成的 E3 连接酶配体-接头偶联物,包含基于 Pomalidomide 的 cereblon 配体和 2 单元 PEG 接头。 | |||
T83655 |
DLIN-MC2-DMA
DLin-M-C2-DMA |
Others | Others |
DLIN-MC2-DMA (DLin-M-C2-DMA) 是一种脂质膜,是一种潜在的核酸载体。 | |||
T18819 |
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride
|
Others; Ligand for E3 Ligase | Others; PROTAC |
Thalidomide-O-amido-PEG2-C2-NH2 hydrochloride 包含一个 E3 连接酶配体和一个 linker。 Thalidomide-O-amido-PEG2-C2-NH2 盐酸盐可用作治疗癌症的免疫调节剂。 | |||
T23599 |
Ab42-IN-C2
Ab42-inhibitor-C2,Ab42 inhibitor-C2,Ab42 inhibitor C2 |
||
Ab42-IN-C2 is an Aβ1-42 inhibitor. | |||
T39777 |
XL388-C2-NH2
XL388-C2-NH2 |
||
XL388-C2-NH2 is a monomeric compound. | |||
T28393 |
Pfn1-IN-C2
Pfn1 inhibitor C2 |
||
Pfn1-IN-C2, an inhibitor of Profilin1 (Pfn1), has been shown to reduce the overall level of cellular filamentous (F)-actin, slow EC migration and proliferation, and inhibit the angiogenic ability of EC both in vitro and ex vivo. | |||
T18818 |
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride
|
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
Thalidomide-O-amido-PEG-C2-NH2 hydrochloride 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是一种合成的 E3 连接酶配体-linker 偶联物。它可用于 PROTAC 的合成分子。 | |||
T32747 |
Licorice saponin C2
Saponin C2, from licorice,Licoricesaponin C2 |
||
Licorice saponin C2 is an oleanane-type triterpene oligoglycoside extracted from the air-dried root of Glycyrrhiza uralensis. | |||
T40726 |
Azide-C2-Azide
Azide-C2-Azide |
||
Azide-C2-Azide is a cleavable linker vital in ADC synthesis. Azide-C2-Azide joins cytotoxic drugs to antibodies, enabling precise delivery to cells or proteins. The cleavable nature ensures controlled drug release, optimizing ADC effectiveness. | |||
T39597 |
diABZI-C2-NH2
diABZI-C2-NH2 |
||
DiABZI-C2-NH2, a STING agonist with a primary amine functionality, is an active analogue. | |||
T9382 |
Thalidomide-NH-C2-PEG3-OH
H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]- |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Thalidomide-NH-C2-PEG3-OH (H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-4-[[2-[2-[2-(2-hydroxyethoxy)ethoxy]ethoxy]ethyl]amino]-) 包含基于 Thalidomide 的 cereblon 配体和 1 个 linker,是 E3 连接酶配体-linker 偶联物,可用于合成 PROTAC BCL-XL 降解剂 XZ739。 | |||
T40806 |
Dimethylamino-PEG2-C2-NH2
Dimethylamino-PEG2-C2-NH2 |
||
Dimethylamino-PEG2-C2-NH2 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T73475 |
SMN-C2
|
DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
SMN-C2 是一种选择性的 SMN2 基因剪接调节剂,是risdiplam类似物,是调节前 mRNA 剪接的选择性 RNA 结合配体,通过结合 SMN2 pre-mRNA 来发挥作用。SMN-C2 具有研究脊髓性肌萎缩症 (SMA) 的潜力。 | |||
T40390 |
Br-PEG6-C2-acid
Br-PEG6-C2-acid |
||
Br-PEG6-C2-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T38505 |
Br-Boc-C2-azido
Br-Boc-C2-azido |
||
Br-Boc-C2-azido is a alkyl/ether-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T23734 |
AMPK activator C2
Compound 2,Compound-2,C2 |
||
AMPK activator C2 is an AMPK allosteric activator. | |||
T39917 |
Thalidomide-O-C2-acid
Thalidomide-O-C2-acid |
||
Thalidomide-O-C2-acid is a compound designed by synthesizing an E3 ligase ligand-linker conjugate. It comprises a cereblon ligand derived from Thalidomide and a linker commonly used in PROTAC technology. | |||
T40217 |
PD0325901-O-C2-dioxolane
PD0325901-O-C2-dioxolane |
||
PD0325901-O-C2-dioxolane is a chemical compound primarily composed of the MEK inhibitor PD0325901. It can be utilized, in conjunction with either a VHL or CRBN E3 ligase ligand, for the synthesis of MEK1/2 degrader. | |||
T17918 |
Thalidomide-O-amido-PEG2-C2-NH2 TFA
E3 Ligase Ligand-Linker Conjugates 24 TFA,Cereblon Ligand-Linker Conjugates 10 TFA |
Others; E3 Ligase Ligand-Linker Conjugate | Others; PROTAC |
Thalidomide-O-amido-PEG2-C2-NH2 TFA (E3 Ligase Ligand-Linker Conjugates 24 TFA) 包含基于 Thalidomide 的 cereblon 配体和 2 个单元的 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T7758 |
Thalidomide-O-amido-PEG3-C2-NH2 TFA
E3 ligase Ligand-Linker Conjugates 14 TFA,Cereblon Ligand-Linker Conjugates 3 (TFA) |
Others; E3 Ligase Ligand-Linker Conjugate; Ligand for E3 Ligase | Others; PROTAC |
Thalidomide-O-amido-PEG3-C2-NH2 TFA (Cereblon Ligand-Linker Conjugates 3 (TFA)) 包含基于 Thalidomide 的 cereblon 配体和 3 个单元的 PEG linker,是一种合成的 E3 连接酶配体-linker 偶联物。 | |||
T39602 |
Boc-NH-PEG4-C2-Boc
Boc-NH-PEG4-C2-Boc |
||
Boc-NH-PEG4-C2-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T18813 |
Thalidomide-PEG2-C2-NH2
Thalidomide-NH-PEG2-C2-NH2 |
Others | Others |
Thalidomide-O-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. | |||
T39227 |
DBCO-C2-SulfoNHS ester
DBCO-C2-SulfoNHS ester |
||
DBCO-C2-SulfoNHS ester is an alkyl/ether-based linker commonly employed for the synthesis of PROTACs, a class of compounds that induce targeted protein degradation. | |||
T38574 |
Trt-PEG4-C2-acid hydrate
Trt-PEG4-C2-acid hydrate |
||
Trt-PEG4-C2-acid (hydrate) is a polyethylene glycol (PEG)-derived linking moiety, specifically designed for the synthesis of Proteolysis Targeting Chimeras (PROTACs). | |||
T40025 |
Pomalidomide-PEG2-CO2H
Pomalidomide 4'-PEG2-acid,Pomalidomide-PEG2-C2-acid |
E3 Ligase Ligand-Linker Conjugate | PROTAC |
Pomalidomide-PEG2-CO2H 是一种合成的 E3 连接酶配体-接头偶联物,包含基于 Pomalidomide 的 cereblon 配体和 2 单元 PEG 接头。 | |||
T36230 |
C2 Ceramide (d14:1/2:0)
C2 Ceramide (d14:1/2:0) |
||
C2 Ceramide (d14:1/2:0) is a bioactive sphingolipid. Dietary administration of C2 ceramide (d14:1/2:0) (100 μM) induces lipotoxic cardiomyopathy via increasing diastolic and systolic diameter as well as reducing fractional shortening and the number of normal cardiac contractile events in Drosophila. | |||
T38547 |
TLR4-IN-C34-C2-COOH
TLR4-IN-C34-C2-COOH |
||
TLR4-IN-C34-C2-COO is a linker compound that incorporates TLR4 inhibitor TLR4-IN-C34. It effectively inhibits TLR4 activity in enterocytes and macrophages. Moreover, it demonstrates a notable ability to mitigate systemic inflammation in murine models of endotoxemia and necrotizing enterocolitis. | |||
T40118 |
Mal-PEG5-C2-NH2 hydrochloride
Mal-PEG5-C2-NH2 hydrochloride |
||
Mal-PEG5-C2-NH2 hydrochloride is a polyethylene glycol (PEG)-based linker utilized for the synthesis of proteolysis targeting chimeras (PROTACs). | |||
T18812 |
Thalidomide-PEG2-C2-NH2 TFA
Thalidomide-NH-PEG2-C2-NH2 TFA |
Others | Others |
Thalidomide-O-amido-PEG3-C2-NH2 TFA, a synthesized E3 ligase ligand-linker conjugate, combines the cereblon ligand based on Thalidomide and a 2-unit PEG linker for use in PROTAC technology[1]. | |||
T18245 |
Mal-C2-cyclohexylcarboxyl-hydrazide TFA
Mal-C2-cyclohexylcarboxyl-hydrazide TFA |
Others | Others |
Mal-C2-cyclohexylcarboxyl-hydrazide TFA is a alkyl chain-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells. | |||
T40224 |
2',3'-cGAMP-C2-PPA
2',3'-cGAMP-C2-PPA |
||
2',3'-cGAMP-C2-PPA (45) is a cyclic di-nucleotide that acts as a STING agonist (US20210015941A1). It is a drug-linker conjugate for antibody-drug conjugates (ADC) used in the targeted treatment of cancer. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
TN1661 |
Ganoderic acid C2
灵芝酸 C2 |
Reductase; Histamine Receptor; Immunology/Inflammation related | Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience |
Ganoderic acid C2 是分离自灵芝的一种三萜化合物, 具有潜在的抗肿瘤生物活性,以及抗组胺、抗衰老和细胞毒性作用。它对rat lens aldose reductase 具有很高的抑制活性,IC50为 3.8 µM。 | |||
T13851 |
Pseudolaric Acid C2
|
Others | Others |
Pseudolaric Acid C2 是一种从 Pseudolarix kaempferi 二萜酸,是大鼠口服和静脉注射后血浆、尿液、胆汁和粪便中 Pseudolaric acid B 的特异性代谢产物。 | |||
T22644 |
C2 Ceramide
Ceramide |
Others | Others |
A potent modulator of cell proliferation and differentiation. | |||
T81397 |
Procyanidin C2
Procyanidine C2 |
||
Procyanidin C2,源自Fagopyrum dibotrys (D. Don) Hara,为酚苷类化合物。 | |||
T11848 |
Licorice glycoside C2
甘草苷 C2 |
Others | Others |
Licorice glycoside C2 is a oleanane-type triterpene oligoglycoside isolated from Glycyrrhiza uralensis. | |||
T2873 |
Ginsenoside Rg2
Chikusetsusaponin I,Panaxoside Rg2,人参皂苷Rg2,Prosapogenin C2,(20S)Ginsenoside Rg2,人参皂苷 Rg2 |
Beta Amyloid; GSK-3; NF-κB | Neuroscience; NF-κB; PI3K/Akt/mTOR signaling; Stem Cells |
Ginsenoside Rg2 (Chikusetsusaponin I) 是一种人参的主要活性成分。它能够降低Aβ1-42积聚,抑制脂多糖介导的VCAM-1和ICAM-1表达的增加。 | |||
T81363 |
Pseudolaric acid C2-O-β-D-glucoside
|
||
Pseudolaric acid C2-O-β-D-glucoside, 一种天然产物,来源于Pseudolarix kaempferi,并通过分离提取得到。 | |||
T38285 |
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) |
Others | Others |
C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))是成熟髓鞘中主要的硫酸盐类化合物。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z)) 在大鼠小脑中发现活跃的髓发生鞘化反应时积累率高于C24 3'-sulfo 半乳糖甘油酰胺。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))与C 型凝集素和免疫球蛋白样受体相互作用使对LMIR5的亲和力高。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))诱导嗜碱细胞产生MCP-1,可通过增加LMIR5激活NFAT,但不能诱导肥大细胞 。C24:1 3'-sulfo Galactosylceramide (d18:1/24:1(15Z))在体外与CD1d 结合,并增加游离小鼠脾细胞的增殖。 | |||
TN3820 |
Demethoxydeacetoxypseudolaric acid B
|
Others | Others |
Demethoxydeacetoxypseudolaric acid B 是 pseudolaric acid C2 的一种代谢物。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPK-01268 |
Complement C2 Protein, Cynomolgus, Recombinant (His)
C2,CO2,Complement C2,C3/C5 convertase,ARMD... |
Cynomolgus | HEK293 Cells |
Single nucleotide polymorphism (SNP) of complement component 2 (C2) has been found to be significantly associated with hepatocellular carcinoma (HCC). Significantly lower C2 expression was found at HCC compared to healthy controls, and C2 was associated with TNM stages. Higher C2 expression was significantly associated with better prognosis, and multivariate analysis showed that C2 was also an independent factor for the prognosis of HCC. | |||
TMPY-00686 |
Complement C2 Protein, Human, Recombinant (His)
CO2,complement component 2,ARMD14 |
Human | HEK293 Cells |
Complement C2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 82.5 kDa and the accession number is P06681-1. | |||
TMPY-00264 |
NPC2 Protein, Rat, Recombinant (His)
Niemann-Pick disease, type C2 |
Rat | HEK293 Cells |
NPC2 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.9 kDa and the accession number is Q8CHN5. | |||
TMPY-01114 |
NPC2 Protein, Human, Recombinant (His)
HE1,Niemann-Pick disease, type C2,EDDM1 |
Human | HEK293 Cells |
NPC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is P61916-1. | |||
TMPJ-00601 |
Apolipoprotein C-II/APOC2 Protein, Human, Recombinant (His)
Apolipoprotein C2,Apolipoprotein C-II,APC2... |
Human | E. coli |
APOC2 activates the lipoprotein lipase in capillaries, which hydrolyzes triglycerides and thus provides free fatty acids for cells. APOC2 is component of the very low density lipoprotein (VLDL) fraction in plasma. It is also an activator of several triacylglycerol lipases. The association of APOC2 with plasma chylomicrons, VLDL, and HDL is reversible, a function of the secretion and catabolism of triglyceride-rich lipoproteins, and changes rapidly. Defects in APOC2 are the cause of hyperlipoprot... | |||
TMPJ-01443 |
HChFc2 Protein, Mouse, Recombinant (His)
C2 factor,HCF-2,Host cell factor 2,Hcfc2 |
Mouse | E. coli |
Host cell factor 2(HCFC2) is a cytoplasmic protein. It contains 2 fibronectin type-III domains.HCFC2 binds KMT2A/MLL1, as component of the MLL1/MLL complex.Hcfc2 negative regulation of transcription from RNA polymerase II promoter. | |||
TMPY-03447 |
Complement C2 Protein, Mouse, Recombinant (His)
complement component 2 |
Mouse | HEK293 Cells |
Complement C2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 84.2 kDa and the accession number is P21180-1. | |||
TMPH-00772 |
Leghemoglobin C2 Protein, Glycine max, Recombinant (His)
|
Glycine max | E. coli |
Provides oxygen to the bacteroids. This role is essential for symbiotic nitrogen fixation. | |||
TMPY-04990 |
NPC2 Protein, Mouse, Recombinant (His)
2700012J19Rik,HE1,AA408070,AU045843,Niemann-Pick disease, ty... |
Mouse | HEK293 Cells |
NPC2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.9 kDa and the accession number is Q9Z0J0. | |||
TMPY-00687 |
Complement C2 Protein, Human, Recombinant (hFc)
ARMD14,complement component 2,CO2 |
Human | HEK293 Cells |
Complement C2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110 kDa and the accession number is P06681-1. | |||
TMPH-00947 |
APOC2 Protein, Human, Recombinant (His & SUMO)
ApoC-II,APC2,Apolipoprotein C-II,Apolipoprotein |
Human | E. coli |
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL. APOC2 Protein, Human, Recomb... | |||
TMPY-03497 |
AKR1C2 Protein, Human, Recombinant (His)
AKR1C2,HBAB,SRXY8,AKR1C-pseudo,aldo-keto reductase ... |
Human | E. coli |
AKR1C2 is a member of the aldo/keto reductase superfamily, which consists of more than 4 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. AKR1C2 gene shares high sequence identity with three other gene ... | |||
TMPJ-00207 |
AKR1C2 Protein, Human, Recombinant
3-Alpha-HSD3,Chlordecone Reductase Homolog HAKRD,2-Diol Dehy... |
Human | E. coli |
Aldo-Keto Reductase Family 1 Member C2 (AKR1C2) plays a role in concert with the 5-α/5-β-Steroid Reductases to convert Steroid hormones into the 3-α/5-α and 3-α/5-β-Tetrahydrosteroids. AKR1C2 catalyzes the inactivation of the most potent androgen 5-α-Dihydrotestosterone (5-α-DHT) to 5-α-Androstane-3-α, 17-β-diol (3-α-diol). | |||
TMPJ-01128 |
SHH Protein, Human, Recombinant (C24II)
HHG-1,Sonic Hedgehog Protein,SHH |
Human | E. coli |
SHH Protein, Human, Recombinant (C24II) is expressed in E. coli expression system. The predicted molecular weight is 20 KDa and the accession number is Q15465. | |||
TMPJ-00666 |
CLIC2 Protein, Human, Recombinant (His)
CLIC2,XAP121,Chloride Intracellular Channel Protein... |
Human | E. coli |
Chloride Intracellular Channel Protein 2 (CLIC2) is a critical component of all living cells; it regulatescellular traffic of Chloride ion and it can be inserted into membranes anf form chloride ion channels. Membrane insertion seems to be redox-regulated and may occur only under oxydizing conditions, channel activity depends on the pH. CLIC2 is involved in regulating membrane potential and organic solute transport. CLIC2 modulates the activity of RYR2 and inhibits Calcium influx. CLIC2 can be d... | |||
TMPY-06210 |
KLRC2 Protein, Human, Recombinant (hFc)
CD159c,NKG2-C,NKG2C |
Human | HEK293 Cells |
KLRC2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.4 kDa and the accession number is P26717-1. | |||
TMPY-00060 |
Influenza A H6N2 (A/chicken/Guangdong/C273/2011) Hemagglutinin/HA Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H6N2 | Baculovirus Insect Cells |
Influenza A H6N2 (A/chicken/Guangdong/C273/2011) Hemagglutinin/HA Protein (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 59.6 kDa and the accession number is I6PXD2. | |||
TMPH-02173 |
TRBC2 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Constant region of T cell receptor (TR) beta chain. Alpha-beta T cell receptors are antigen specific receptors which are essential to the immune response and are present on the cell surface of T lymphocytes. Recognize peptide-major histocompatibility (MH) (pMH) complexes that are displayed by antigen presenting cells (APC), a prerequisite for efficient T cell adaptive immunity against pathogens. Binding of alpha-beta TR to pMH complex initiates TR-CD3 clustering on the cell surface and intracell... | |||
TMPK-01225 |
MRC2 Protein, Human, Recombinant (His)
C-type lectin domain family 13 member E, Endocytic receptor ... |
Human | HEK293 Cells |
MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellular fibronectin type II domain that binds to and internalizes collagen, suggesting that it may play a role in modulating renal fibrosis. MRC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.64 kDa and t... | |||
TMPH-02171 |
TRBC2 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
TRBC2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 43.6 kDa and the accession number is A0A5B9. | |||
TMPH-00906 |
SLC25A6 Protein, Human, Recombinant (His & KSI)
|
Human | E. coli |
SLC25A6 Protein, Human, Recombinant (His & KSI) is expressed in E. coli expression system with N-6xHis-KSI tag. The predicted molecular weight is 20.2 kDa and the accession number is P12236. | |||
TMPY-00522 |
KLC2 Protein, Human, Recombinant (His & GST)
kinesin light chain 2 |
Human | Baculovirus Insect Cells |
KLC2 Protein, Human, Recombinant (His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 96.8 kDa and the accession number is Q9H0B6-1. | |||
TMPJ-01252 |
CLEC2D Protein, Mouse, Recombinant (His)
Clec2d,Clr-b,Clrb,Ocil,Osteoclast inhibitory lectin... |
Mouse | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Sensing tissue damage is an ancient function of immune cells that is central to the regulation of inflammation, tissue repair, and immunity. The C-type lectin receptor Clec2d as a sensor of cell death, which directly detects histones released during necrosis and thus contributes to inflammation and immunopathology. The Clec2d pathway may also be exploited to favor a pro-inflammatory anti-tumor response. And tu... | |||
TMPH-01731 |
MYBPC2 Protein, Human, Recombinant (His)
|
Human | E. coli |
Thick filament-associated protein located in the crossbridge region of vertebrate striated muscle a bands. In vitro it binds MHC, F-actin and native thin filaments, and modifies the activity of actin-activated myosin ATPase. It may modulate muscle contraction or may play a more structural role. MYBPC2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 49.5 kDa and the accession number is Q14324. | |||
TMPY-01118 |
SLC27A4/FATP4 Protein, Human, Recombinant (His)
FATP4,IPS,solute carrier family 27 (fatty acid transporter),... |
Human | HEK293 Cells |
SLC27A4/ATG4B complex might act as a new potential therapeutic target of lung tumor chemotherapy. The solute carrier 27A (SLC27A) gene family encodes fatty acid transport proteins (FATPs) and includes 6 members. Autism spectrum disorders (ASD) are now recognized as disorders caused by impaired early brain development, it is possible that functional abnormalities of SLC27A genes may contribute to the pathogenesis of ASD. The expression of SLC27A3 and SLC27A4 in human neural stem cells derived fro... | |||
TMPY-03889 |
STC2 Protein, Human, Recombinant (His)
stanniocalcin 2,STC-2,STCRP |
Human | HEK293 Cells |
STC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.1 kDa and the accession number is O76061. | |||
TMPY-03279 |
STC2 Protein, Human, Recombinant (hFc)
STC-2,STCRP,stanniocalcin 2 |
Human | HEK293 Cells |
STC2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 57.7 kDa and the accession number is O76061. | |||
TMPK-01230 |
CLEC2D Protein, Human, Recombinant (hFc & Avi)
Lectin-like NK cell receptor,LLT-1,OCIL,LLT1,Lectin-like tra... |
Human | HEK293 Cells |
C-type lectin domain family 2, member D (CLEC2D) is implicated in the immune response. Pre-eclampsia and HIV infection have opposing immune responses. The contrasting expression of CLEC2D in HIV infection and pre-eclampsia is demonstrative of the immunosuppressive and pro-inflammatory roles of the respective pathologies. However, this implication may be confounded by highly active anti-retroviral treatment (HAART). | |||
TMPK-01167 |
TEM7R/PLXDC2 Protein, Mouse, Recombinant (His)
PLXDC2,TEM7R |
Mouse | HEK293 Cells |
Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Plxdc2 is a type I transmembrane protein with some homology to nidogen and to plexins. It is expressed in a highly discrete and dynamic pattern in the developing nervous system, with prominent expression in various patterning centres. TEM7R/PLXDC2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-Hi... | |||
TMPY-02685 |
ST6GALNAC2 Protein, Mouse, Recombinant (His)
ST6GalNAc,II,ST6-N-acetylgalactosaminide α-2,6-sialyltransfe... |
Mouse | HEK293 Cells |
ST6GALNAC2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.7 kDa and the accession number is P70277. | |||
TMPY-01892 |
Desmocollin 2/DSC2 Protein, Human, Recombinant (His)
ARVD11,desmocollin 2,DGII/III,DSC3,DG2,CDHF2 |
Human | HEK293 Cells |
Desmocollin 2/DSC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 75 kDa and the accession number is Q02487-1. | |||
TMPJ-01171 |
SHH Protein, Mouse, Recombinant (C25II)
HHG-1,SHH,Sonic Hedgehog Protein |
Mouse | E. coli |
SHH Protein, Mouse, Recombinant (C25II) is expressed in E. coli expression system. The predicted molecular weight is 18-20 KDa and the accession number is Q62226. | |||
TMPH-01074 |
CDC20 Protein, Human, Recombinant (His & Myc)
Cell division cycle protein 20 homolog,CDC20,p55CDC |
Human | E. coli |
CDC20 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 62.2 kDa and the accession number is Q12834. | |||
TMPY-04932 |
SUC2 Protein, Saccharomyces cerevisiae, Recombinant (His)
|
Saccharomyces cerevisiae | P. pastoris (Yeast) |
SUC2 Protein, Saccharomyces cerevisiae, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 60 kDa and the accession number is P00724-1. | |||
TMPH-02296 |
C2orf69 Protein, Human, Recombinant (His)
Mitochondrial protein C2orf69,C2orf69 |
Human | E. coli |
May play a role in the respiratory chain. | |||
TMPH-02642 |
ECHS1 Protein, Mouse, Recombinant (C225S, HA & His)
mECH,Enoyl-CoA hydratase, mitochondrial,SCEH,mECH1,ECHS1 |
Mouse | Baculovirus Insect Cells |
Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate. Has high substrate specificity for crotonyl-CoA and moderate specificity for acryloyl-CoA, 3-methylcrotonyl-CoA and methacrylyl-CoA. It is noteworthy that binds tiglyl-CoA, but hydrates only a small amount of this substrate. ECHS1 Protein, Mouse, Recombinant (C225S, HA & His) is expressed in Baculovirus insect cells with N-10xHis, C-HA tag. The predicted molecular weight is 32.0... | |||
TMPH-02333 |
SLC25A19 Protein, Human, Recombinant (His)
|
Human | E. coli |
Mitochondrial transporter mediating uptake of thiamine pyrophosphate (ThPP) into mitochondria. SLC25A19 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-10xHis tag. The predicted molecular weight is 37.0 kDa and the accession number is Q9HC21. | |||
TMPH-03373 |
SLC2A1 Protein, Rat, Recombinant (His & Myc)
|
Rat | E. coli |
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. SLC2A1 ... | |||
TMPH-02079 |
SPTLC2 Protein, Human, Recombinant (His & SUMO)
|
Human | E. coli |
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis. SPTLC2 Protein, Human, Recomb... | |||
TMPY-00288 |
Influenza A H6N2 (A/chicken/Guangdong/C273/2011) Hemagglutinin/HA1 Protein (His)
Harvey rat sarcoma viral oncogene homolog |
H6N2 | HEK293 Cells |
Influenza A H6N2 (A/chicken/Guangdong/C273/2011) Hemagglutinin/HA1 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 38.4 kDa and the accession number is I6PXD2. | |||
TMPJ-01380 |
ST6GalNAc2 Protein, Human, Recombinant (His)
GalNAc α-2,SIATL1,SIAT7B,GalNAc Alpha-2,SIAT7-B,Sialyltransf... |
Human | HEK293 Cells |
Alpha-N-Acetylgalactosaminide α-2,6-Sialyltransferase 2 (ST6GALNAC2) belongs to the glycosyltransferase 29 family that adds sialic acids to the non-reducing ends of glycoconjugates. At the cell surface, these modifications play roles in cell-cell and cell-substrate interactions, bacterial adhesion and protein targeting. ST6GALNAC2 is localized to the Golgi apparatus membrane. ST6GALNAC2 is highly expressed in lactating mammary glands and the adult testis; it is expressed at lower levels in the k... | |||
TMPY-01451 |
MESDC2 Protein, Human, Recombinant (His)
MESD,mesoderm development candidate 2,BOCA |
Human | HEK293 Cells |
MESD (Mesoderm Development LRP Chaperone) is a Protein Coding gene. LDLR chaperone MESD, also known as Mesoderm development protein, Mesoderm development candidate 2, Renal carcinoma antigen NY-REN-61, and MESDC2, is a member of the MESD family. It is widely expressed in the thyroid, placenta, and other tissues. MESDC2 is a chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). The LDLR maturation activity reside... | |||
TMPY-02439 |
Rac2 Protein, Human, Recombinant (His)
p21-Rac2,HSPC022,Gx,EN-7,ras-related C3 botulinum t... |
Human | E. coli |
Ras-related C3 botulinum toxin substrate 2 (Rac2) is a small G-protein belonging to the Ras subfamily of the GTPase family. Rac2 acts as an "on / off" switch for signal transduction cascades and motilities. When GDP is attached to the small G-protein, the enzyme is inactivated. Release of the GDP and replace of the GTP cativate the GTPasee. Rac2 remains active until the GTP is hydrolyzed to GDP. Rac2 is a hematopoietic-specific Rho family GTPase implicated as an important constituent of the NADP... | |||
TMPY-06285 |
KLRC2 Protein, Human, Recombinant (His)
CD159c,NKG2C,NKG2-C |
Human | HEK293 Cells |
KLRC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.12 kDa and the accession number is P26717-1. | |||
TMPY-04040 |
CLEC2D Protein, Rat, Recombinant (hFc)
C-type lectin domain family 2, member D |
Rat | HEK293 Cells |
Lectin-like transcript 1 (LLT1) encoded by CLEC2D gene is a C-type lectin-like molecule interacting with human CD161 (NKR-P1A) receptor expressed by natural killer cells and subsets of T cells. CLEC2D transcripts were detected primarily in hematopoietic cell lines and were found to be co-induced by the same activation signals. Although very low amounts of putative soluble CLEC2D protein isoforms could be produced by transfectants, CLEC2D isoforms 2 and 4 were efficiently expressed. CLEC2D uses g... | |||
TMPH-02123 |
SLC2A9 Protein, Human, Recombinant (His)
|
Human | E. coli |
Urate transporter, which may play a role in the urate reabsorption by proximal tubules. Does not transport glucose, fructose or galactose. | |||
TMPY-04642 |
Desmocollin 2/DSC2 Protein, Rat, Recombinant (hFc)
desmocollin 2 |
Rat | HEK293 Cells |
Desmocollin 2/DSC2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 101.6 kDa and the accession number is Q3T1K6. | |||
TMPJ-01222 |
LRRC25 Protein, Human, Recombinant (His)
Leucine-rich repeat-containing protein 25,MAPA,Monocyte and ... |
Human | HEK293 Cells |
Leucine-rich repeat-containing protein 25(LRRC25) is a single-pass type I membrane protein and contains 3 LRR (leucine-rich) repeats. The protein expressed in plasmacytoid dendritic cells (PDC), monocyte-derived dendritic cells (MDDC), granulocytes, monocytes, B-lymphocytes, peripheral blood leukocytes, spleen, bone marrow, and, to a lesser extent, lymph nodes, fetal liver, and appendix but not in thymus. The protein may be involved in the activation of cells of innate and acquired immunity. | |||
TMPH-02122 |
SLC2A1 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Facilitative glucose transporter, which is responsible for constitutive or basal glucose uptake. Has a very broad substrate specificity; can transport a wide range of aldoses including both pentoses and hexoses. Most important energy carrier of the brain: present at the blood-brain barrier and assures the energy-independent, facilitative transport of glucose into the brain. In association with BSG and NXNL1, promotes retinal cone survival by increasing glucose uptake into photoreceptors. SLC2A1 ... | |||
TMPY-02037 |
TSC22D1 Protein, Mouse, Recombinant (His)
Tgfb1i4,TSC-22,Tsc,Egr5,Tsc22,TSC22 domain... |
Mouse | E. coli |
TSC22D1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P62500-2. | |||
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