Cat. No. | Product Name | CAS No. | Purity | Chemical Structure |
---|---|---|---|---|
TQ0003L | 740 Y-P(TFA)(1236188-16-1 free base)
化合物740 Y-P(TFA)
|
TQ0003L | 98% |
|
740 Y-P(TFA)(1236188-16-1 free base) (740YPDGFR(TFA)) 是一种有效的细胞渗透性 PI3K 激活剂。 | ||||
T72374 | PI3K/mTOR Inhibitor-12
化合物 PI3K/mTOR Inhibitor-12
|
2891692-83-2 | 98% |
|
PI3K/mTOR Inhibitor-12为口服有效且选择性的PI3K/mTOR抑制剂,对PI3Kα和mTOR的IC50分别为0.06 nM及3.12 nM,表现出抗肿瘤活性且肝毒性较低。 | ||||
T72713 | PI3K/VEGFR2-IN-1
化合物 PI3K/VEGFR2-IN-1
|
2851067-08-6 | 98% |
|
PI3K/VEGFR2-IN-1是一种具有双重抑制效应的化合物,对PI3K和VEGFR2的IC50分别为2.21 μM和68 μM,能够诱导细胞凋亡(apoptosis),在癌症研究中应用。 | ||||
T12467 | PI4KIII beta inhibitor 3
化合物 T12467
|
1245319-54-3 | 98% |
|
PI4KIII beta inhibitor 3 is a novel and high effective inhibitor of PI4KIIIβ (IC50 of 5.7 nM). | ||||
T74782 | CXJ-2
化合物 CXJ-2
|
2919976-92-2 | 98% |
|
CXJ-2,一种环状肽,对EDP(弹性蛋白衍生肽)具中等亲和力。该化合物有效抑制PI3K/ERK通路,减少肝星状细胞的增殖与迁移,展现出显著的抗纤维化能力。 | ||||
T11610 | Idelalisib D5
化合物 T11610
|
1830330-31-8 | 98% |
|
Idelalisib D5 is a deuterium-labeled Idelalisib. Idelalisib is a highly selective and orally bioavailable p110δ inhibitor. | ||||
TN5201 | Uncarinic acid E
化合物 TN5201
|
277751-61-8 | 98% |
|
Uncarinic acid E has anti-cancer activity, it induces apoptosis in HepG2 cells via accumulation of p53, alters the Bax/Bcl-2 ratio, and activates caspases, resul... | ||||
T16908 | Sonolisib
化合物 T16908
|
502632-66-8 | 98% |
|
Sonolisib is an irreversible and pan-isoform inhibitor of PI3K (IC50=0.1 nM (p110α), 1.0 nM (p120γ), 2.9 nM (p110δ)). | ||||
T12458 | PI3K-IN-9
化合物 T12458
|
2360875-63-2 | 98% |
|
PI3K-IN-9 is a potent and selective inhibitor of PI3Kδ(IC50 of 8.9 nM). | ||||
T17066 | Umbralisib hydrochloride
化合物 T17066
|
1532533-78-0 | 98% |
|
Umbralisib hydrochloride is a novel PI3Kδ inhibitor (IC50 and EC50 of 22.2 nM and 24.3 nM, respectively). Umbralisib hydrochloride is also active against CK1ε (E... | ||||
TN5050 | Sprengerinin C
化合物 TN5050
|
88861-91-0 | 98% |
|
Sprengerinin C exerts anti-tumorigenic effects in hepatocellular carcinoma via inhibition of proliferation and angiogenesis and induction of apoptosis, it can st... | ||||
T10660L2 | CAL-130 Racemate
化合物 T10660L2
|
474012-90-3 | 98% |
|
CAL-130 Racemate is the racemate of CAL-130. CAL-130 is a PI3Kδ and PI3Kγ inhibitor (IC50s: 1.3 and 6.1 nM). | ||||
T77629 | FD274
化合物FD274
|
2641899-38-7 | 98% |
|
FD274 是一种高效的 PI3K/mTOR 双重抑制剂,对 PI3Kα/β/γ/δ 和 mTOR 具有抑制作用, IC50 分别为 0.65 nM、1.57 nM、0.65 nM、0.42 nM 和 2.03 nM。 FD274 在 AML 细胞系抗增殖实验中显示出显着的抗增殖活性。 FD274 在 HL-60 异种移... | ||||
T15800 | LY117018
化合物 T15800
|
63676-25-5 | 98% |
|
LY117018 shows antiproliferative effects on breast cancer cell lines. LY117018 is a Raloxifene analog and is a selective estrogen receptor modulator. | ||||
T11818 | LAS191954
化合物 T11818
|
1403947-26-1 | 98% |
|
LAS191954 is a selective, potent and orally active PI3Kδ inhibitor for inflammatory diseases treatment(IC50 : 2.6 nM). | ||||
TN4213 | Hirsutenone
化合物 TN4213
|
41137-87-5 | 98% |
|
Hirsutenone has potent antioxidant activity, it shows significant free radical scavenging activity and exhibits inhibition effect on the mitochondrial lipid pero... | ||||
T3229 | Cytochalasin D
细胞松弛素D
|
22144-77-0 | 98% |
|
Cytochalasin D is an actin inhibitor, the removal of actin stress fibers is crucial for the chondrogenic differentiation. It may be an inhibitor of some fertiliz... | ||||
TN3323 | Monomethyl lithospermate
紫草酸单甲酯
|
933054-33-2 | 98% |
|
Monomethyl lithospermate (Lithospermic acid monomethyl ester) 具有潜在的抗病毒活性,通过激活PI5K/Akt信号传导,减轻体内大脑中动脉闭塞小鼠缺血性中风损伤,并在体外保护氧葡萄糖剥夺/复氧诱导的SHSY-3Y细胞。Monomethyl lithosperma... | ||||
TN3753 | Dalbergioidin
化合物 TN3753
|
30368-42-4 | 98% |
|
Dalbergioidin exhibits tyrosinase inhibitory activity with an IC50 of 20 mM. It shows a melanin biosynthesis inhibition zone in the culture plate of Streptomyces... | ||||
TN1367 | Alismol
化合物Alismol
|
87827-55-2 | 98% |
|
Alismol has antihypertensive action, it decreases cardiac output, heart rate and left ventricular pressure, but it increases coronary flow, it has been used for ... |