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46

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T34119	PPS Silent Surfactant PPS
	PPS Silent Surfactant is a cleavable detergent used in biochemistry, and especially in proteomics, to enhance protein denaturation and solubility.
T19235	CHAPS	Others	Others
	CHAPS 是一种两性离子洗涤剂，是一种 Cholic acid 的衍生物，可溶解膜蛋白。它用于稳定各种蛋白质-DNA 复合物，并可以保留溶液中蛋白质的生化活性。
T83847	SP-A (196-215) (human) TFA Surfactant Protein A,SPA4
	表面活性蛋白A（SP-A）（196-215）是一种合成肽，与人类SP-A的C末端碳水化合物识别域的196至215氨基酸序列相对应。当浓度为1和10 µM时，它能抑制JAWSII鼠树突细胞中由LPS诱导的TNF-α释放。SP-A（196-215）（75 µM）促使JAWSII细胞吞噬P. aeruginosa。通过气管内给药，SP-A（196-215）（50 µg/动物）降低了小鼠P. aeruginosa感染模型的疾病严重程度和肺部形成菌落数。
T29909	ALS-I ALS1,Acid-Liable Surfactant-1,ALS 1,ALS-1
	ALS-1 is an acid-Liable surfactant.
T20639	Lauryl benzalkonium chloride Lauralkonium chloride,NSC 85508,NSC85508,十二烷基二甲基苄基氯化铵,Benzododecinium chloride,NSC-85508	Others	Others
	Lauryl benzalkonium chloride (Benzododecinium chloride) 是阳离子表面活性剂的一种。
T12356	Palmitoylcarnitine Palmitoyl DL-carnitine	Endogenous Metabolite	Metabolism
	Palmitoylcarnitine (Palmitoyl DL-carnitine) 是一种线粒体脂肪酸氧化中间体，可作为表面活性剂。
T66152	NDSB-211	Others	Others
	NDSB-211 是一种具有较小的疏水端并能温和地溶解蛋白质的表面活性剂，可用于蛋白提取和分析。
T22981	Tetradecyltrimethylammonium bromide MitMAB,Cetrimide,tetradecyl trimethyl ammonium bromide,十四烷基三甲基溴化铵	Dynamin	Cytoskeletal Signaling
	Tetradecyltrimethylammonium bromide (MitMAB) 是一种具有不对称结构的阳离子表面活性剂，是一种有机结构单元。
T0307	Tyloxapol 四丁酚醇,Triton WR1339,四丁酚醛	NF-κB; LPL Receptor	GPCR/G Protein; NF-κB
	Tyloxapol (Triton WR1339) 是一种烷基芳基聚醚醇型非离子液体聚合物，是一种表面活性稳定剂，可诱导动物高脂血症。
T65687	CAPS N-Cyclohexyl-3-aminopropanesulfonic acid	Others	Others
	CAPS (N-Cyclohexyl-3-aminopropanesulfonic acid) 是一种表面活性剂，可作为化学发光增强剂，可用于开发深海原位分析仪。
T12950	Sodium laureth sulfate Sodium lauryl polyoxyethylene ether sulfate,月桂醇聚氧乙烯醚硫酸酯钠盐	Others	Others
	Sodium laureth sulfate (Sodium lauryl polyoxyethylene ether sulfate) 是一种阴离子活性剂，具有优良的去污，分散，乳化，润湿等性能。
T19524	Poloxamer 407	Others	Others
	Poloxamer 407 是非离子型表面活性剂，具有 100% 的活性，对细胞相对无毒性的。它常与染料 AM 酯一起使用，来提高其水溶性。
T0401	Benzethonium chloride Hyamine,Phemeride,苄索氯铵,Quatrachlor	AChR	Neuroscience
	Benzethonium chloride (Quatrachlor) 是合成季铵盐，具有表面活性剂、防腐剂和广谱抗菌特性。它作用于在爪蟾卵母细胞，抑制人重组α7和α4β2神经元烟碱性乙酰胆碱受体。
T7872	Monolaurin	Others	Others
	Monolaurin 是椰子油中的一种表面活性剂和乳化剂。它抑制葡萄球菌、链球菌、加德纳菌、念珠菌和嗜血杆菌的生长，并减少促炎细胞因子的产生。
T38253	Lauroyl-L-carnitine (chloride) Lauroyl-L-carnitine Hydrochloride
	Lauroyl-L-carnitine (chloride) (Lauroyl-L-carnitine Hydrochloride)是一种酰基肉碱和表面活性剂，已被用于渗透猪肠细胞，以输送极性荧光探针荧光黄。
T13947	Tween 80 吐温 80	Others	Others
	Tween 80 是一种非离子型的表面活性剂和乳化剂。Tween 80 可以减少细菌附着并抑制生物膜的形成。Tween 80 可以有效提高化合物在水相中的溶解度，因此被广泛用作药理学实验中的助溶剂。
T16335	Nonaethylene glycol monododecyl ether Nonaoxyethylene monododecyl ether,Polidocanol,聚醚醇	Others	Others
	Nonaethylene glycol monododecyl ether (Polidocanol) 是一种非离子表面活性剂和聚乙二醇清洁剂，可用于蛋白质分离和纯化，以及用于形成初始聚结的 O/W 乳剂液滴。
T0336	Benzalkonium chloride 苯扎氯铵,Alkyldimethylbenzylammonium chloride	Others; Antibacterial	Microbiology/Virology; Others
	Benzalkonium chloride (Alkyldimethylbenzylammonium chloride) 是一种含有季铵基团的阳离子表面活性剂，也是一种抗菌剂，在滴眼液中用作防腐剂。
T2188	Thonzonium Bromide 嘧苯十六铵,通佐溴胺	Proton pump; Antibacterial; Autophagy	Autophagy; Membrane transporter/Ion channel; Microbiology/Virology
	Thonzonium bromide 是一种单阳离子表面活性剂，在结构上与 Farnesol 相似的抗菌剂。它以剂量依赖的方式抑制质子转运 (EC50=69 μM)。在体外可抑制 RANKL 诱导的破骨细胞形成和骨吸收，并在体内阻止 LPS 诱导的骨丢失。
T0824	4-Nonylphenol polyethoxylate Nonoxynol,Nonoxinol-9,壬苯醇醚	COX	Immunology/Inflammation; Neuroscience
	4-Nonylphenol polyethoxylate (Nonoxinol-9) 是一种表面活性剂，普遍用作避孕药中的杀精剂。
T64297	Triton X-100
	Triton X-100 是一种溶解脂膜的非变性洗涤剂。Triton X-100 通常用于实验室，并在生产过程的不同阶段应用于疫苗。Triton X-100 被列为某些疫苗,包括裂解病毒流感疫苗的赋形剂。Triton X-100 是一种非离子表面活性剂。
T0920	Ambroxol 氨溴索,氨溴索碱,Ambroxolum,NA-872	P450; Autophagy	Autophagy; Metabolism
	Ambroxol (NA-872) 是前药溴己辛的活性代谢产物，是一种分泌溶解剂，具有强效祛痰作用，用于治疗与粘液或过多粘液相关的呼吸道疾病。它可诱导肺组织细胞自噬，有用于帕金森氏病和神经性戈谢病的研究潜力。它是一种葡糖脑苷脂酶伴侣，可增加葡糖脑苷脂酶的活性。
T20649	Lauryl trisiloxane Tm-121,Tm 121,Dodecylheptamethyltrisiloxide,Tm121
	Lauryl trisiloxane is a surfactant.
T20269	Dibutyl tartrate AI3 00396,AI3-00396,AI300396
	Dibutyl tartrate is an agent of chiral surfactant.
T20640	LAPAO Lauramidopropylamine oxide
	Lauramide propyl amine oxide is an amphoteric surfactant
T20671	Lauramidopropyl betaine Amphitol 20AB,Amphoteric L,Anpholex LB 2
	Lauramidopropyl betaine is a very low irritant amphoteric surfactant.
T20650	Triethanolamine oleate Tea-oleate,Trietol
	Triethanolamine oleate is a nonionic surfactant
T19287	TPGS-750-M DL-alpha-Tocopherol methoxypolyethylene glycol succinate	Others	Others
	DL-α-tocopherol methoxypolyethylene glycol succinate solution (TPGS-750-M) is a hydrophilic lipid molecule that acts as a surfactant.
T20598	Sorbitan monolaurate Emasol L 10,Emasol L-10,Arlacel20,Arlacel-20,Arlacel 20,Emasol L10
	Sorbitan monolaurate, a non-ionic surfactant, is widely used as a stabilizer and emulsifier in pharmaceutical formulations, food, and cosmetic industries.
T28188	Nonoxynol-9 N 9,N-9,N9
	Nonoxynol-9 is an inhibitor of human epidermal growth factor receptor-2 (HER2). It is also used as a surfactant and functions as a spermatocide.
T40802	Poloxamer 188
	Poloxamer 188, a nonionic linear copolymer possessing surfactant properties, demonstrates anti-thrombotic, anti-inflammatory, and cytoprotective activities across different tissue injury models.
T33540	Myristoyl glutamic acid N-Myristoyl-L-glutamic acid,N-Tetradecanoyl-L-glutamic acid,Glutamic acid, N-myristoyl-, l-	Antibacterial	Microbiology/Virology
	Myristoyl glutamic acid （N-Myristoyl-L-glutamic acid）是一种肉豆蔻酰谷氨酸，是一种可添加进化好妆品中的表面活性剂，具有发泡和部分抑菌活性。
T40438	PEG-8 laurate
	PEG-8 laurate is a monofunctional surfactant and skin penetration enhancer. It disrupts the skin barrier and facilitates the formation of elastic vesicles when synthesized.
T39438	Lithium dodecyl sulfate
	Lithium dodecyl sulfate is an anionic detergent and surfactant, suitable as a substitute for sodium dodecyl sulfate (SDS) in electrophoresis applications performed under lower temperatures. Lithium dodecyl sulfate is also applicable in the synthesis of nanomaterials and chromatography processes.
T37871	Octaethylene glycol monododecyl ether
	C12E8 is a nonionic surfactant formed by the ethoxylation of dodecanol, yielding a compound with eight repeated units of ethylene glycol. It can be used for solubilization of membrane-bound proteins.
T25628	Lapyrium Lapyrium cation
	Lapyrium is a cationic surfactant that is used in personal care products as a biocide and antistatic. It is also used by the chloride salt, lapyrium chloride, in waste-water treatment and corrosion inhibition formulations.
T74306	Chol-PEG
	Chol-PEG 是一种非离子表面活性剂囊泡，可用于血液持续给药系统。
T39852	Triton X-45(n=4)
	Triton X-45, a nonionic surfactant with a low Hydrophile-Lypophile Balance (HLB) value, is a dispersible compound in the aqueous solution at room temperature. With a Krafft point above room temperature, Triton X-45 shows promise for research on the Hepatitis C Virus (HCV).
T73906	Myristoyl glutamic acid sodium
	Myristoyl glutamic acid sodium，即化妆品/面霜中常用的肉豆蔻酰谷氨酸成分。作为氨基酸类表面活性剂，其清洁能力温和且具备发泡性和轻度抑菌作用。
T38379	4-tert-Octylphenol diethoxylate
	4-tert-Octylphenol diethoxylate is a degradation product of the multi-purpose surfactant, Triton X. A known environmental contaminant, 4-tert-octylphenol diethoxylate is reported to be an endocrine disruptor in animal and human research studies, producing weak estrogenic effects.
T38825	Glyco-diosgenin
	Glyco-diosgenin serves as a synthetic surfactant and detergent utilized in the extraction of proteins from membranes. This compound finds application in studies related to the structure and function of proteins, as well as in single-particle cryo-electron microscopy (cryoEM) studies specifically targeted at membrane proteins.
T7536	H-Leu-Leu-Ome.HCl	Others	Others
	H-Leu-Leu-Ome.HCl 又称Stearamidoethyl diethylamine（SDEA）是一种重要的化合物，它是二乙胺的衍生物，广泛用于各种产品的研究和生产，包括用作化妆品中的表面活性剂、食品中的乳化剂和聚合物中的稳定剂。
T38103	Defensin HNP-3 (human) (trifluoroacetate salt)
	Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 μM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd...
T77228	Polyoxyethylene Sorbitan Monostearate
	Polyoxyethylene Sorbitan Monostearate 是一种由饱和脂肪酸硬脂酸 (C18:0) 构成的酯，广泛应用作药用辅料，包括表面活性剂、乳化剂、增溶剂和润湿剂。作为药用助剂，其主要作用是改善药物制剂的稳定性、溶解性和加工性，同时对药物的吸收、分布、代谢和消除 (ADME) 过程具有影响。
T81276	Rhodamine B hydrazide
	Rhodamine B hydrazide 是一优良的亚硫酸盐探针，呈现无色且不荧光。其荧光强度与亚硫酸盐浓度呈正相关（5-800 ng/mL；检测限=1.4 ng/mL (3σ)）。在亚硫酸盐作用下，Rhodamine B hydrazide 与还原的溶解氧形成的超氧自由基反应，生成荧光产物 Rhodamine B。Tween 80 表面活性剂的胶束能够增强荧光信号。Rhodamine B hydrazide 在 554 nm 处有最大吸收峰，在 574 nm 处有最高荧光发射峰。
T34030	Phosphatidyl choline (from egg yolk) Azolectin,PC. Phosphatidyl choline,L-α-Lecithin
	Phosphatidylcholines (PC) are a class of phospholipids that incorporate choline as a headgroup. They are a major component of biological membranes and can be easily obtained from a variety of readily available sources, such as egg yolk or soybeans, from w

化合物

PPS Silent Surfactant

Cat.No: T34119

Synonym: PPS

Cat.No: T19235

Target: Others

SP-A (196-215) (human) TFA

Cat.No: T83847

Synonym: Surfactant Protein A,SPA4

Cat.No: T29909

Synonym: ALS1,Acid-Liable Surfactant-1,ALS 1,ALS-1

Lauryl benzalkonium chloride

Cat.No: T20639

Synonym: Lauralkonium chloride,NSC 85508,NSC85508,十二烷基二甲基苄基氯化铵,Benzododecinium chloride,NSC-85508

Target: Others

Palmitoylcarnitine

Cat.No: T12356

Synonym: Palmitoyl DL-carnitine

Target: Endogenous Metabolite

Cat.No: T66152

Target: Others

Tetradecyltrimethylammonium bromide

Cat.No: T22981

Synonym: MitMAB,Cetrimide,tetradecyl trimethyl ammonium bromide,十四烷基三甲基溴化铵

Target: Dynamin

Cat.No: T0307

Synonym: 四丁酚醇,Triton WR1339,四丁酚醛

Target: NF-κB, LPL Receptor

Cat.No: T65687

Synonym: N-Cyclohexyl-3-aminopropanesulfonic acid

Target: Others

Sodium laureth sulfate

Cat.No: T12950

Synonym: Sodium lauryl polyoxyethylene ether sulfate,月桂醇聚氧乙烯醚硫酸酯钠盐

Target: Others

Cat.No: T19524

Target: Others

Benzethonium chloride

Cat.No: T0401

Synonym: Hyamine,Phemeride,苄索氯铵,Quatrachlor

Target: AChR

Cat.No: T7872

Target: Others

Lauroyl-L-carnitine (chloride)

Cat.No: T38253

Synonym: Lauroyl-L-carnitine Hydrochloride

Cat.No: T13947

Synonym: 吐温 80

Target: Others

Nonaethylene glycol monododecyl ether

Cat.No: T16335

Synonym: Nonaoxyethylene monododecyl ether,Polidocanol,聚醚醇

Target: Others

Benzalkonium chloride

Cat.No: T0336

Synonym: 苯扎氯铵,Alkyldimethylbenzylammonium chloride

Target: Others, Antibacterial

Thonzonium Bromide

Cat.No: T2188

Synonym: 嘧苯十六铵,通佐溴胺

Target: Proton pump, Antibacterial, Autophagy

4-Nonylphenol polyethoxylate

Cat.No: T0824

Synonym: Nonoxynol,Nonoxinol-9,壬苯醇醚

Target: COX

Cat.No: T64297

Cat.No: T0920

Synonym: 氨溴索,氨溴索碱,Ambroxolum,NA-872

Target: P450, Autophagy

Lauryl trisiloxane

Cat.No: T20649

Synonym: Tm-121,Tm 121,Dodecylheptamethyltrisiloxide,Tm121

Dibutyl tartrate

Cat.No: T20269

Synonym: AI3 00396,AI3-00396,AI300396

Cat.No: T20640

Synonym: Lauramidopropylamine oxide

Lauramidopropyl betaine

Cat.No: T20671

Synonym: Amphitol 20AB,Amphoteric L,Anpholex LB 2

Triethanolamine oleate

Cat.No: T20650

Synonym: Tea-oleate,Trietol

Cat.No: T19287

Synonym: DL-alpha-Tocopherol methoxypolyethylene glycol succinate

Target: Others

Sorbitan monolaurate

Cat.No: T20598

Synonym: Emasol L 10,Emasol L-10,Arlacel20,Arlacel-20,Arlacel 20,Emasol L10

Cat.No: T28188

Synonym: N 9,N-9,N9

Cat.No: T40802

Myristoyl glutamic acid

Cat.No: T33540

Synonym: N-Myristoyl-L-glutamic acid,N-Tetradecanoyl-L-glutamic acid,Glutamic acid, N-myristoyl-, l-

Target: Antibacterial

Cat.No: T40438

Lithium dodecyl sulfate

Cat.No: T39438

Octaethylene glycol monododecyl ether

Cat.No: T37871

Cat.No: T25628

Synonym: Lapyrium cation

Cat.No: T74306

Triton X-45(n=4)

Cat.No: T39852

Myristoyl glutamic acid sodium

Cat.No: T73906

4-tert-Octylphenol diethoxylate

Cat.No: T38379

Glyco-diosgenin

Cat.No: T38825

H-Leu-Leu-Ome.HCl

Cat.No: T7536

Target: Others

Defensin HNP-3 (human) (trifluoroacetate salt)

Cat.No: T38103

Polyoxyethylene Sorbitan Monostearate

Cat.No: T77228

Rhodamine B hydrazide

Cat.No: T81276

Phosphatidyl choline (from egg yolk)

Cat.No: T34030

Synonym: Azolectin,PC. Phosphatidyl choline,L-α-Lecithin

Cat. No.	Product Name	Target	Signaling Pathways
T3603	Sodium lauryl sulfoacetate 月桂醇磺基乙酸酯钠,鱼腥草,新鱼腥草素钠,Sodium houttuyfonate	NF-κB; MAPK	MAPK; NF-κB
	Sodium lauryl sulfoacetate (Sodium houttuyfonate) 是一种植物来源的固体阴离子表面活性剂，也是一种具有抗免疫抑制作用的免疫佐剂。
T5666	Dipotassium glycyrrhizinate	Virus Protease	Microbiology/Virology
	Dipotassium glycyrrhizinate 是一种具有抗过敏和抗炎活性的阴离子表面活性剂。
TN6891	1-Hexanol hexan-1-ol,正己醇	Others	Others
	1-Hexanol (hexan-1-ol) 是一种伯醇，是一种表面活性剂，通过非质子机制解偶联线粒体呼吸，可用于增强工业过程中的界面性能。
T4859	1-Monomyristin rac-Glycerol 1-myristate,Glyceryl myristate,1-肉豆蔻酸单甘油酯,肉豆寇酸单甘油酯,Monomyristin,2,3-Dihydroxypropyl tetradecanoate	Others; FAAH; Endogenous Metabolite; Antibacterial; Autophagy; Antifungal	Autophagy; Metabolism; Microbiology/Virology; Neuroscience; Others
	1-Monomyristin (2,3-Dihydroxypropyl tetradecanoate) 是从 Serenoa repens 中提取的，抑制脂肪酸酰胺水解酶活性(IC50=18 μM) 和 2-油酰甘油的水解 (IC50=32 μM)。它对白色念珠菌有抗真菌活性，对金黄色葡萄球菌和聚集性放线菌有抗菌活性。
T4943	Monoolein 1-Oleoyl-rac-glycerol,甘油单油酸酯	Others; Endogenous Metabolite	Metabolism; Others
	Monoolein (1-Oleoyl-rac-glycerol) 是内源性代谢产物的一种。
T5083	L-Cysteic acid monohydrate L-磺基丙氨酸一水合物,3-Sulfo-L-alanine Monohydrate	Endogenous Metabolite; GluR	Metabolism; Neuroscience
	L-Cysteic acid monohydrate (3-Sulfo-L-alanine Monohydrate) 是内源性代谢产物的一种。
T4947	3-Hydroxybutyric acid Butanoic acid,3-羟基丁酸	Endogenous Metabolite	Metabolism
	3-Hydroxybutyric acid (Butanoic acid) 是一种人内源性代谢物，在 I 型糖尿病中升高。它能够调节膜脂的性质。
T30004	Ammonium laurate AI3 00287,AI3-00287,AI300287
	Ammonium laurate is a surfactant.

天然产物

Sodium lauryl sulfoacetate

Cat.No: T3603

Synonym: 月桂醇磺基乙酸酯钠,鱼腥草,新鱼腥草素钠,Sodium houttuyfonate

Target: NF-κB, MAPK

Dipotassium glycyrrhizinate

Cat.No: T5666

Target: Virus Protease

Cat.No: TN6891

Synonym: hexan-1-ol,正己醇

Target: Others

Cat.No: T4859

Synonym: rac-Glycerol 1-myristate,Glyceryl myristate,1-肉豆蔻酸单甘油酯,肉豆寇酸单甘油酯,Monomyristin,2,3-Dihydroxypropyl tetradecanoate

Target: Others, FAAH, Endogenous Metabolite, Antibacterial, Autophagy, Antifungal

Cat.No: T4943

Synonym: 1-Oleoyl-rac-glycerol,甘油单油酸酯

Target: Others, Endogenous Metabolite

L-Cysteic acid monohydrate

Cat.No: T5083

Synonym: L-磺基丙氨酸一水合物,3-Sulfo-L-alanine Monohydrate

Target: Endogenous Metabolite, GluR

3-Hydroxybutyric acid

Cat.No: T4947

Synonym: Butanoic acid,3-羟基丁酸

Target: Endogenous Metabolite

Ammonium laurate

Cat.No: T30004

Synonym: AI3 00287,AI3-00287,AI300287

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