首页工具

登录

搜索结果

Search Results for " pressure-lowering "

15

抑制剂 & 化合物

6

天然产物

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T0106	Methazolamide L584601,醋甲唑胺,CL 8490	Carbonic Anhydrase	Metabolism
	Methazolamide (CL 8490) 是一种磺胺衍生物，用作碳酸酐酶 (carbonic anhydrase) 抑制剂，对人 carbonic anhydrase II 的 Ki=为 14 nM。它是降低眼压的药物，能够抑制由青光眼及其他眼病引起的眼压升高的作用。
T4661	PKG drug G1	PKA	Tyrosine Kinase/Adaptors
	PKG drug G1 靶向作用于PKG Iα。它通过 C42 PKGIα 非依赖性机制，促进血管舒张以及血压降低。
T12478L	Pinacidil 吡那地尔,S 1230,P 1134,S-1230,P-1134,P1134	Potassium Channel	Membrane transporter/Ion channel
	Pinacidil (P 1134) 是钾通道的有效激活剂。Pinacidil 通过打开 K+-通道使血管平滑肌超极化，显示出抗高血压活性。它显著改善再灌注功能和心脏顺应性。它具有直接的心脏保护作用。
T15718	Latanoprost acid	GPR	Endocrinology/Hormones; GPCR/G Protein
	Latanoprost acid 是前列腺素受体的选择性激动剂，通过抑制 c-fos/NFATc1 通路抑制 RANKL 诱导的破骨细胞生成和功能。拉坦前列素酸可用于降低眼内压力的研究。
T26453	A 81282 A81282,A-81282,Abbott 81282,Abbott-81282
	A 81282 is a selective antagonist of angiotensin receptors. It has the activity of lowering blood pressure.
T25483	H-0106 Dihydrochloride H 0106 2HCl,H0106 2HCl,H0106 Dihydrochloride
	H-0106 Dihydrochloride is an inhibitor of ROCK that acts by applying strong intraocular pressure (IOP)-lowering effects into the eyes of monkeys.
T25482	H-0104 Dihydrochloride H0104 Dihydrochloride,H0104 2HCl,H 0104 Dihydrochloride,H 0104 2HCl,H-0104 2HCl
	H-0104 Dihydrochloride is an inhibitor of ROCK that acts by applying potent intraocular pressure (IOP)-lowering effects into the eyes of monkeys.
T81915	LPP Tripeptide
	LPP Tripeptide 是一种降血压作用的三肽，常用于高血压的研究领域。
T0112L	Diltiazem Diltiazem free base,Dilticard,地尔硫卓,CRD-401,CRD401,Dilzen,CRD 401
	Diltiazem is a non-dihydropyridine (non-DHP) calcium channel blocker that relaxes the smooth muscle in arterial walls, thus opening (dilating) arteries, allowing easier blood flow, and lowering blood pressure, and is used to treat hypertension, angina pec
T76499	Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine
	Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine 是一种含有4个氨基酸构成的降血压肽，具有血管紧张素转换酶 (ACE) 抑制作用，适用于高血压研究。
T68098	Midaglizole (±)-DG5128 free base,DG5128 free base,(±)-DG5128 free base ; DG5128 free base
	Midaglizole ((±)-DG5128 free base, DG5128 free base) 是一种有效的α2-adrenoceptor 拮抗剂。Midaglizole 是一种降血糖药。Midaglizole 在具有升高血压并降低血糖水平的作用。
T39063	Azilsartan mepixetil
	Azilsartan mepixetil is a potent angiotensin II receptor antagonist with enhanced efficacy and prolonged duration of action. It exhibits more prominent and sustained effects in lowering blood pressure and heart rate, while maintaining a high level of safety. Furthermore, Azilsartan mepixetil demonstrates optimal protective efficacy for cardiovascular and renal functions. Hence, it holds promise for the research and treatment of hypertension, chronic heart failure, and diabetic nephropathy.
T16388	Omidenepag isopropyl	Prostaglandin Receptor	GPCR/G Protein; Immunology/Inflammation
	Omidenepag isopropyl is converted to the active product Omidenepag during corneal penetration. Omidenepag isopropyl is a selective EP2 receptor agonist. Omidenepag isopropyl displays only a weak affinity for EP1, EP2, and FP receptors. Omidenepag isopropy
T78624	OPC-163493	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	OPC-163493 是一种口服活性的肝脏靶向线粒体解偶联剂，能够减少 Δψ 及线粒体 ROS 生成。它展现了抗糖尿病与心血管益处，可在中风/高血压大鼠模型中降低血压、延长存活时间并改善肾脏功能。
T72213	Efonidipine hydrochloride NZ-105 hydrochloride
	Efonidipine(NZ-105)盐酸盐是T 型和L 型钙离子通道双重阻断剂。

化合物

Cat.No: T0106

Synonym: L584601,醋甲唑胺,CL 8490

Target: Carbonic Anhydrase

Cat.No: T4661

Target: PKA

Cat.No: T12478L

Synonym: 吡那地尔,S 1230,P 1134,S-1230,P-1134,P1134

Target: Potassium Channel

Latanoprost acid

Cat.No: T15718

Target: GPR

Cat.No: T26453

Synonym: A81282,A-81282,Abbott 81282,Abbott-81282

H-0106 Dihydrochloride

Cat.No: T25483

Synonym: H 0106 2HCl,H0106 2HCl,H0106 Dihydrochloride

H-0104 Dihydrochloride

Cat.No: T25482

Synonym: H0104 Dihydrochloride,H0104 2HCl,H 0104 Dihydrochloride,H 0104 2HCl,H-0104 2HCl

Cat.No: T81915

Cat.No: T0112L

Synonym: Diltiazem free base,Dilticard,地尔硫卓,CRD-401,CRD401,Dilzen,CRD 401

Lactalbumin B (50-53) Alpha [Lactorphin Alpha], bovine

Cat.No: T76499

Cat.No: T68098

Synonym: (±)-DG5128 free base,DG5128 free base,(±)-DG5128 free base ; DG5128 free base

Azilsartan mepixetil

Cat.No: T39063

Omidenepag isopropyl

Cat.No: T16388

Target: Prostaglandin Receptor

Cat.No: T78624

Target: Reactive Oxygen Species

Efonidipine hydrochloride

Cat.No: T72213

Synonym: NZ-105 hydrochloride

Cat. No.	Product Name	Target	Signaling Pathways
T0022	Taurine 牛磺酸,2-Aminoethanesulfonic acid	LDL; Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	Taurine (2-Aminoethanesulfonic acid) 是一种含硫氨基酸的有机渗透剂，为胆汁盐的形成提供底物，并在调节细胞内游离钙浓度方面发挥作用，有激活脂肪细胞自噬的能力。
T2782L	Catharanthine Tartrate(2468-21-5(free base))	Calcium Channel	Membrane transporter/Ion channel; Metabolism
	Catharanthine Tartrate(2468-21-5(free base)) 是从马达加斯加长春花中分离得到的天然产物，Catharanthine Tartrate 抑制电压操作的L 型Ca2+通道，具有抗癌和降血压活性。
T6S0654	Isocorynoxeine 7-Isocorynoxeine,异去氢钩藤碱	5-HT Receptor	GPCR/G Protein; Neuroscience
	Isocorynoxeine (7-Isocorynoxeine) 是钩藤中的一种生物碱，剂量依赖性抑制5-HT2A 受体介导的电流反应，IC50为 72.4 μM。
T3744	Veratric acid Veratrumenoic acid,藜芦酸,3,4-Dimethoxybenzoic acid	Reactive Oxygen Species; COX	Immunology/Inflammation; Metabolism; Neuroscience; NF-κB
	Veratric acid (3,4-Dimethoxybenzoic acid) 是从蔬菜和水果中得到的一种可口服多酚，具有抗氧化、保护心血管和抗炎活性。当细胞受到 UVB 辐射时，它能够减少上调的 COX-2 表达，降低 PGE2 和 IL-6 水平。
T3332	Isosteviol 异甜菊醇,(-)-Isosteviol	IL Receptor; Potassium Channel; TNF; NF-κB; Reactive Oxygen Species; COX; Topoisomerase	Apoptosis; DNA Damage/DNA Repair; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism; Neuroscience; NF-κB
	Isosteviol ((-)-Isosteviol) 是一种常见的天然甜味剂，属于四环二萜糖苷，是甜菊糖苷通过酸催化水解产生的。它抑制 DNA 聚合酶和 DNA 拓扑异构酶，具有抗菌、抗癌和抗结核作用。
TN2350	Pingpeimine A	Others	Others
	Pingpeimine A has the effect of expectorating and lowering blood pressure. Derived from Fritillaria sibiricum.

天然产物

Cat.No: T0022

Synonym: 牛磺酸,2-Aminoethanesulfonic acid

Target: LDL, Endogenous Metabolite, Autophagy

Catharanthine Tartrate(2468-21-5(free base))

Cat.No: T2782L

Target: Calcium Channel

Cat.No: T6S0654

Synonym: 7-Isocorynoxeine,异去氢钩藤碱

Target: 5-HT Receptor

Cat.No: T3744

Synonym: Veratrumenoic acid,藜芦酸,3,4-Dimethoxybenzoic acid

Target: Reactive Oxygen Species, COX

Cat.No: T3332

Synonym: 异甜菊醇,(-)-Isosteviol

Target: IL Receptor, Potassium Channel, TNF, NF-κB, Reactive Oxygen Species, COX, Topoisomerase

Cat.No: TN2350

Target: Others

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼