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Search Results for " macrolide "

71

抑制剂 & 化合物

32

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T22228	Tylvalosin tartrate 酒石酸乙酰异戊酰泰乐菌素,Acetylisovaleryltylosin Tartrate	Antibacterial; Antibiotic	Microbiology/Virology
	Tylvalosin tartrate (Acetylisovaleryltylosin Tartrate) 是一种对革兰氏阳性细菌具有抗性的大环内酯类抗生素。
T21572	Erythromycin A enol ether	Others	Others
	Erythromycin A enol ether 是大环内酯类抗生素红霉素A 的降解产物。
T22439	Tilmicosin phosphate 磷酸替米考星,替米考星磷酸盐	Antibacterial; Antibiotic	Microbiology/Virology
	Tilmicosin phosphate 是一种抗生素，可研究曼氏杆菌和巴氏杆菌相关的牛羊呼吸系统疾病。
T0777	Tilmicosin LY-177370,替米考星,EL-870	Antibacterial; Antibiotic	Microbiology/Virology
	Tilmicosin (EL-870) 是一种抗生素，可研究曼氏杆菌和巴氏杆菌相关的牛羊呼吸系统疾病。
T7096	Tildipirosin	Antibacterial; Antibiotic	Microbiology/Virology
	Tildipirosin 是一种具有长效抗菌作用的大环内酯抗生素。
T4267	Tulathromycin A CP 472295,Draxxin,Tulathromycin,托拉菌素 A	Antibacterial; Antibiotic	Microbiology/Virology
	Tulathromycin A (CP 472295) 是一种大环内酯类抗生素，靶向细菌核糖体抑制蛋白质合成 (IC50=0.26 µM)，具有免疫调节作用。它可研究牛和猪的呼吸道疾病。
T9950	ElteN378	mTOR	PI3K/Akt/mTOR signaling
	Elte N378 是一种高效的合成 FKBP12 抑制剂，Ki 为 0.5 nM，是一种低原子量配体，其亲和力与大环内酯类雷帕霉素相当。
T1434	Clarithromycin A-56268,克拉霉素	P450; ribosome; MRP; Antibacterial; Antibiotic; Autophagy	Autophagy; Immunology/Inflammation; Metabolism; Microbiology/Virology
	Clarithromycin (A-56268) 具有广谱的抗菌活性。它抑制 CYP3A4催化的三唑仑 α-羟基化，IC50(Ki) 值为 56 (43) μM。它抑制 HERG 钾电流。它可削弱连接 hERG1 和 PI3K 的信号通路影响自噬流。
T0580	4-Pentynoic acid Propargylacetic acid,戊炔酸	Others	Others
	4-Pentynoic acid (Propargylacetic acid) 已用于与 1-溴-1-炔烃在 Pd 催化剂存在下的反应，产生具有生物活性的烯醇内酯。它还用于通过双乙炔的闭环复分解合成具有细胞毒性的大环内酯。
T16551	Pladienolide B	Apoptosis	Apoptosis
	Pladienolide B 是一种有效的剪接体抑制剂，是从钝顶链霉菌 Mer-12 中分离出的大环内酯类化合物，其作用靶向剪接体的 SF3B1 亚单位。Pladienolide B 通过抑制前 mRNA 剪接发挥抗肿瘤作用，诱导调亡。Pladienolide B 具有抗肿瘤活性，可用于研究白血病和淋巴肿瘤。
T6334	Ridaforolimus AP23573,Deforolimus,MK-8669	mTOR; Autophagy	Autophagy; PI3K/Akt/mTOR signaling
	Ridaforolimus (AP23573) 是亲脂性大环内酯类抗生素雷帕霉素的小分子非前药类似物，具有潜在的抗肿瘤活性。它是一种有效和选择性的 mTOR 抑制剂，在 HT-1080 细胞中抑制 S6 磷酸化的 IC50值为 0.2 nM。
T26116	Rokitamycin
	Rokitamycin is a macrolide antibiotic produced from strains of Streptomyces kitasatoensis.
T26410	A 26771B A-26771B,A26771B
	A 26771B is an antibiotic in the class of macrolide lactone.
T25303	Deltamycin A1
	Deltamycin A1 is a novel macrolide antibiotic.
T24777	Sedecamycin T-2636A,T-2636,Ro 23-0731/000,NSC 145117
	Sedecamycin is a 17-membered macrolide antibiotic. It is used for treating swine dysentery.
T20686	RK 397 RK397,RK-397
	RK 397 is an antibiotic of oxopentaene macrolide.
T23140	PF-945863	Others	Others
	macrolide antibiotic
T25778	Maridomycin Turimycin EP(sub 3),Maridomycin III
	Maridomycin is a macrolide antibiotic.
T26057	Relomycin Relomycinum,Dihydrotylosin,Relomicina
	Relomycin is a macrolide antibiotic.
T28121	Mycinamicin I Antibiotic A 11725 I,Mycinomycin I,A 11725 I
	Mycinamicin I is a macrolide antibiotic.
T7148L2	Josamycin propionate BRN 1677122,BRN-1677122,BRN1677122
	Josamycin propionate is a macrolide antibiotic.
T25868	Niddamycin F-3463,F 3463,F3463
	Niddamycin is a new macrolide antibiotic.
T25027	Albocycline TA-2407,Ingramycin
	Albocycline is a Macrolide antibiotic from Streptomyces bruneogriseus nov. sp. MCRL-0129; specifically anti-staphylococcal, including antibiotic-resistant strains.
T25039	Aldgamycin G 8-Deoxyaldgamycin F
	Aldgamycin G is a Macrolide antibiotic against Gram-positive bacteria isolated from Streptomyces avidinii.
T30038	Amphidinolide F
	Amphidinolide F is a new cytotoxic macrolide
T21148	Troleandomycin Cyclamycin,Matromycin T,AI3-50166,Aovine,Micotil
	Troleandomycin is a macrolide antibiotic and is similar to Erythromycin.
T25587	Kujimycin A Desacetyllankamycin
	Kujimycin A is a macrolide antibiotics agent from various strains of Streptomyces. It has great activity against some Gram-positive bacteria.
T26211	Sporeamicin A SRM A,L-53-18 A,L53-18 A,L 53-18 A,SRM-A
	Sporeamicin A is a new macrolide antibiotic from Saccaropolyspora.
T25762	Lucimycin FI1163,Antibiotic 1163 F.I.,FI 1163,FI-1163,NSC 143257
	Lucimycin is a macrolide antibiotic from cultures of Streptomyces lucensis.
T26088	Rimocidin Rimocidine
	Rimocidin is a macrolide antifungal compound isolated from Streptomyces rimosus.
T26124	Roseofungin
	Roseofungin is a polyenic macrolide antibiotic with the subgroup of carbonyl conjugated pentaenes.
T25992	Propionylmaridomycin Propionylmaridomycin I
	Propionylmaridomycin is a macrolide antibiotic.
T25038	Aldgamycin E
	Aldgamycin E is a neutral macrolide antibiotic agent from culture filtrates of Streptomyces lavendulae. Methanolysis produces methyl algarosides A & B.
T7148L1	Josamycin HCl Josamycin hydrochloride,Leucomycin A3 hydrochloride
	Josamycin HCl is a macrolide antibiotic.
T25643	Lavendofuseomycin
	Lavendofuseomycin is a macrolide pentaene antibiotic.
T25621	Lankacidinol A Lankacidinol 14-acetate,Antibiotic T-2636D,P 2636 D,P2636 D,P-2636 D
	Lankacidinol A is a metabolite of macrolide antibiotic.
T30037	Amphidinolide C
	Amphidinolide C is a potent cytotoxic 25-membered macrolide from marine dinoflagellate Amphidinium sp.
T26344	Yl 704 A1 Yl-704 A1,Yl704 A1
	Yl 704 A1 is a primary component of macrolide antibiotic YL-704 from Streptomyces platensis subsp. malvinus.
T28046	Mirosamicin A 11725 II,Antibiotic AR 5-2
	Mirosamicin is a macrolide antibiotic, it has antimicrobial effect against gram-positive bacteria, some gram-negative bacteria and mycoplasma.
T36183	Neospiramycin I
	Neospiramycin I is a macrolide antibiotic and derivative of spiramycin I.1It is active against the macrolide-sensitive KB210, but not the macrolide-resistant KB224, strain ofS. aureus(MICs = 3.12 and >100 μg/ml, respectively), as well asB. cereus,B. subtilis,M. luteus,E. coli, andK. pneumoniae(MICs = 1.56, 3.12, 3.12, 0.2, 50, and 12.5 μg/ml, respectively). Neospiramycin I binds toE. coliribosomes with an IC50value of 1.2 μM. It protects against mortality in a mouse model ofS. pneumoniaetype III...
T25955	Picromycin Antibiotic B 62169A,Amaromycin,Albomycetin,Pikromycin
	Picromycin is a 14-membered macrolide antibiotic and Prolyl endopeptidase (PREP) inhibitor. Pikromycin shows activity against gram-positive bacteria including mycobacteria.
T16382	Oleandomycin	Others	Others
	Oleandomycin is similar to Erythromycin has antimicrobial activity. Oleandomycin is a macrolide antibiotic structurally closely related to Erythromycin.
T32624	Leinamycin DC107,(+)-Leinamycin,DC 107,DC-107,Antibiotic DC 107
	Leinamycin is a thiazole containing macrolide that is extracted from Streptomyces possibly used as a DNA alkylator.
T71647	Rustmicin
	Rustmicin is a 14-membered macrolide identified as an inhibitor of plant pathogenic fungi.
T36533	SCH 725674
	SCH 725674 is an antifungal macrolide originally isolated from Aspergillus. It inhibits the growth of S. cerevisiae and C. albicans in vitro (MICs = 8 and 32 μg/ml, respectively).
T28626	Rutamycin Oligomycin D,A272,A 272,A-272
	Rutamycin is a macrolide antibiotic of the oligomycin group obtained from Streptomyces rutgersensis. It inhibits various ATPases and uncouples oxidative phosphorylation from electron transport.
T25721	Lienomycin
	Lienomycin is a pentaene macrolide antitumor antibiotic generated by Actinomyces vendargensis Struyk et Stheeman. It has inonphore-like action.
T24043	Erythromycin glutamate
	Erythromycin glutamate is a macrolide bacteriostatic antibiotic. This antibiotic is metabolized through the liver and inhibits cytochrome enzyme P450A 3A41.
T25624	Lankamycin Kujimycin B,A20338-N2,Antibiotic A-20338-N2,A-20338-N2,A 20338-N2
	Lankamycin is a macrolide antibiotic from various strains of Streptomyces. It may have significant activity against some Gram positive bacteria.
T26075	Rhizopodin
	Rhizopodin is a potent natural macrolide antibiotic that effectively affects the actin cytoskeleton at nanomolar concentrations.

化合物

Tylvalosin tartrate

Cat.No: T22228

Synonym: 酒石酸乙酰异戊酰泰乐菌素,Acetylisovaleryltylosin Tartrate

Target: Antibacterial, Antibiotic

Erythromycin A enol ether

Cat.No: T21572

Target: Others

Tilmicosin phosphate

Cat.No: T22439

Synonym: 磷酸替米考星,替米考星磷酸盐

Target: Antibacterial, Antibiotic

Cat.No: T0777

Synonym: LY-177370,替米考星,EL-870

Target: Antibacterial, Antibiotic

Cat.No: T7096

Target: Antibacterial, Antibiotic

Tulathromycin A

Cat.No: T4267

Synonym: CP 472295,Draxxin,Tulathromycin,托拉菌素 A

Target: Antibacterial, Antibiotic

Cat.No: T9950

Target: mTOR

Cat.No: T1434

Synonym: A-56268,克拉霉素

Target: P450, ribosome, MRP, Antibacterial, Antibiotic, Autophagy

4-Pentynoic acid

Cat.No: T0580

Synonym: Propargylacetic acid,戊炔酸

Target: Others

Cat.No: T16551

Target: Apoptosis

Cat.No: T6334

Synonym: AP23573,Deforolimus,MK-8669

Target: mTOR, Autophagy

Cat.No: T26116

Cat.No: T26410

Synonym: A-26771B,A26771B

Cat.No: T25303

Cat.No: T24777

Synonym: T-2636A,T-2636,Ro 23-0731/000,NSC 145117

Cat.No: T20686

Synonym: RK397,RK-397

Cat.No: T23140

Target: Others

Cat.No: T25778

Synonym: Turimycin EP(sub 3),Maridomycin III

Cat.No: T26057

Synonym: Relomycinum,Dihydrotylosin,Relomicina

Cat.No: T28121

Synonym: Antibiotic A 11725 I,Mycinomycin I,A 11725 I

Josamycin propionate

Cat.No: T7148L2

Synonym: BRN 1677122,BRN-1677122,BRN1677122

Cat.No: T25868

Synonym: F-3463,F 3463,F3463

Cat.No: T25027

Synonym: TA-2407,Ingramycin

Cat.No: T25039

Synonym: 8-Deoxyaldgamycin F

Amphidinolide F

Cat.No: T30038

Cat.No: T21148

Synonym: Cyclamycin,Matromycin T,AI3-50166,Aovine,Micotil

Cat.No: T25587

Synonym: Desacetyllankamycin

Cat.No: T26211

Synonym: SRM A,L-53-18 A,L53-18 A,L 53-18 A,SRM-A

Cat.No: T25762

Synonym: FI1163,Antibiotic 1163 F.I.,FI 1163,FI-1163,NSC 143257

Cat.No: T26088

Synonym: Rimocidine

Cat.No: T26124

Propionylmaridomycin

Cat.No: T25992

Synonym: Propionylmaridomycin I

Cat.No: T25038

Cat.No: T7148L1

Synonym: Josamycin hydrochloride,Leucomycin A3 hydrochloride

Lavendofuseomycin

Cat.No: T25643

Cat.No: T25621

Synonym: Lankacidinol 14-acetate,Antibiotic T-2636D,P 2636 D,P2636 D,P-2636 D

Amphidinolide C

Cat.No: T30037

Cat.No: T26344

Synonym: Yl-704 A1,Yl704 A1

Cat.No: T28046

Synonym: A 11725 II,Antibiotic AR 5-2

Neospiramycin I

Cat.No: T36183

Cat.No: T25955

Synonym: Antibiotic B 62169A,Amaromycin,Albomycetin,Pikromycin

Cat.No: T16382

Target: Others

Cat.No: T32624

Synonym: DC107,(+)-Leinamycin,DC 107,DC-107,Antibiotic DC 107

Cat.No: T71647

Cat.No: T36533

Cat.No: T28626

Synonym: Oligomycin D,A272,A 272,A-272

Cat.No: T25721

Erythromycin glutamate

Cat.No: T24043

Cat.No: T25624

Synonym: Kujimycin B,A20338-N2,Antibiotic A-20338-N2,A-20338-N2,A 20338-N2

Cat.No: T26075

Cat. No.	Product Name	Target	Signaling Pathways
T0971	Dirithromycin Dirithromycinum,地红霉素,ASE 136,LY237216,Diritromicina,Dirithromycine	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Dirithromycin (LY237216) 是一种红霉素衍生物，是一种具有口服活性的半合成大环内酯类抗生素。它用于治疗许多不同类型的细菌感染。
T2481	Ascomycin FK520,Immunomycin,子囊霉素,FR-900520	Phosphatase; Others; Antibiotic; Parasite; Antifungal	Metabolism; Microbiology/Virology; Others
	Ascomycin (Immunomycin) 是 Tacrolimus 的乙基类似物，具有免疫抑制特性。它也是一种大环聚酮类抗生素，具有抗疟疾、抗真菌和抗痉挛等多种生物活性。它可防止移植排斥，并具有用于各种皮肤病研究的潜力。
T3607	Leucomycin 吉他霉素,Kitasamycin,Leucomycin V,Turimycin	Antibacterial; Antibiotic	Microbiology/Virology
	Leucomycin (Turimycin) 是一种由 Streptomyces kitasatoensis 产生的大环内酯类抗生素。
T1032	Erythromycin 红霉素,E-Mycin	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Erythromycin (E-Mycin) 是由放线菌产生的大环内酯类抗生素。它结合细菌的 50S 核糖体亚基，通过阻断转肽和易位反应来抑制 RNA 依赖性蛋白的合成。
T5037	Midecamycin Antibiotic SF-837,Turimycin P3,Medecamycin A1,Rubimycin,麦迪霉素,Platenomycin B1,Espinomycin A	Antibacterial; Antibiotic	Microbiology/Virology
	Midecamycin (Medecamycin A1) 是乙酰氧基取代的大环内酯类抗生素，对革兰氏阳性和阴性菌有效。
T3629	Gamithromycin ML-1709460,加米霉素	Antibacterial; Antibiotic	Microbiology/Virology
	Gamithromycin (ML-1709460) 是一种可抑制 MmmSC 菌株 B237 和 Tan8 生长的大环内酯类抗菌剂，MIC 值分别为 0.00012 和 0.00006 μg/mL。
T1151	Roxithromycin Roxl-150,罗红霉素,RU-28965	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Roxithromycin (RU-28965) 是半合成的大环内酯类抗生素。
T0474	Erythromycin ethylsuccinate EES,琥乙红霉素	ribosome; HIV Protease; Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology; Proteases/Proteasome
	Erythromycin ethylsuccinate (EES) 是一种由红链霉菌产生的大环内酯类抗生素，有潜力用于多种细菌感染。它具有抗 HIV-1病毒活性。
T21495	Spinosyn A	Others	Others
	Spinosyn A 是聚酮化合物衍生的大环内酯，来自多刺甘蔗多孢菌。Spinosyn A 是有效的杀虫剂。
T0861	Tylosin tartrate 酒石酸泰洛星,酒石酸泰乐菌素	Antibacterial; Antibiotic	Microbiology/Virology
	Tylosin tartrate 是一种大环内酯类抗生素，是 Streptomyces fradiae 的产物。它对革兰氏阳性菌具有高效的抗菌活性。它作为饲料添加剂可促进动物生长。它被用于治疗家禽、猪和牛的细菌性痢疾和呼吸道疾病。
T1419	Azithromycin hydrate CP-62993 dihydrate,阿奇霉素二水物,Azithromycin dihydrate,阿奇霉素二水合物	ribosome; Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Azithromycin hydrate (CP-62993 dihydrate) 是一种大环内酯抗生素，可研究细菌感染。
T7148	JOSAMYCIN EN-141,交沙霉素	Antibacterial; Antibiotic	Microbiology/Virology
	Josamycin (EN-141) 是一种大环内酯类抗生素，对多种病原体有抗菌活性。它对核糖体的解离常数Kd 为 5.5 nM。
T67867	Mycaminosyltylonolide	Antibacterial	Microbiology/Virology
	Mycaminosyltylonolide 是一种大环内酯类抗生素，它是 tyololide 在位置5上具有β - d -mycaminosyl 残基。Mycaminosyltylonolide 是一种有效的抗生素，具有抗菌活性和抑制荧光素酶的合成。
T1003	Tylosin Fradizine,Tylosin A,泰乐菌素,Tylosine,Tylocine	Antibacterial; Antibiotic	Microbiology/Virology
	Tylosin (Tylosine) 是一种兽医用大环内酯类抗生素，是 Streptomyces fradiae 的产物。它对革兰氏阳性菌具有高抗菌活性。它是饲料添加剂用于促进动物生长。它被用于治疗家禽、猪和牛的细菌性痢疾和呼吸道疾病。
T11287	Filipin complex	Antifungal	Microbiology/Virology
	Filipin complex 是一种 28 元环戊烯大环内酯类抗真菌抗生素，由 S. filipinensis、S. avermitilis 和 S. miharaensis 产生的混合物，抑制 PRRSV 病毒进入细胞，通过与膜固醇相互作用发挥作用。
T6194	Fidaxomicin 非达米星,Tiacumicin B,OPT-80,Clostomicin B1,PAR-101	Apoptosis; DNA/RNA Synthesis; Antibacterial; Antibiotic	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology
	Fidaxomicin (Tiacumicin B) 是一种大环RNA 聚合酶抑制剂，具有窄谱活性。它选择性地根除致病性艰难梭菌，对构成正常健康肠道菌群的多种细菌影响很小。
T6062	Brefeldin A BFA,布雷非德菌素 A,Ascotoxin,Cyanein,Decumbin	ATPase; Mitophagy; Antibiotic; Autophagy; HSV; CRISPR/Cas9	Autophagy; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Microbiology/Virology
	Brefeldin A (Cyanein) 属于大环内酯类抗生素，是一种 ATPase 抑制剂 (IC50=0.2 μM)。Brefeldin A 可以诱导肿瘤细胞分化和凋亡，也具有抑制自噬的活性。
T15245	Erythromycin estolate Phtalic anhydride,ilosone	Antibacterial	Microbiology/Virology
	Erythromycin estolate 是红霉素的衍生物，属于大环内酯类抗生素，常用于研究多种细菌感染。酯酸红霉素对胆汁酸转运有抑制作用，可引起肝损伤，主要是胆汁淤积性肝炎。
T6740	Bafilomycin A1 巴佛洛霉素A1,巴佛洛霉素 A1	Apoptosis; Proton pump; Antibacterial; Antibiotic; Autophagy	Apoptosis; Autophagy; Membrane transporter/Ion channel; Microbiology/Virology
	Bafilomycin A1 属于大环内酯类抗生素，是一种 V-ATPase (IC50=0.44 nM)，具有特异性和可逆性。Bafilomycin A1 是自噬晚期阶段抑制剂，阻断自噬体与溶酶体的融合。Bafilomycin A1 也诱导凋亡。
T0819	Spiramycin Espiramicin,螺旋霉素,Sequamycin,Rovamycin,Provamycin,Formacidine	Antibacterial; Antibiotic; Parasite	Microbiology/Virology
	Spiramycin (Rovamycin) 是一种由安博链霉菌产生的大环内酯类抗生素，具有抗细菌和弓形虫活性，并具有抗寄生虫作用。它由 16 个内酯环组成，其上附着 mycaminose，forosamine 和 mycarose 三种糖。
T20879	Tacrolimus monohydrate FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,他克莫司一水合物,FK 506	Phosphatase; Others; Antibacterial; Antibiotic; Autophagy	Autophagy; Metabolism; Microbiology/Virology; Others
	Tacrolimus monohydrate (LCP-Tacro) 是大环内酯类化合物，它与 FK506 结合蛋白 (FKBP) 结合形成复合物并抑制钙调神经磷酸酶，从而抑制 T 淋巴细胞信号转导和 IL-2 转录。具有强免疫抑制特性。
T23505	Venturicidin A	Others	Others
	macrolide antibiotic
T20779	Kitasamycin tartrate Leucomycin tartrate
	Kitasamycin tartrate, a macrolide antibiotic produced by Streptomyces kitasatoensis, has a wide spectrum of antimicrobial activity.
T10582	Borrelidin Treponemycin	Others	Others
	Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei.
T25622	Lankacidins Bundlin A,Lankacidin C,Antibiotic T-2636 C,NSC 145118,Lankacidin
	Lankacidins is an antitumor antibiotic of the macrolide tetraenes family from Streptomyces.
T14995	Concanamycin A X 4357B,刀豆素A,Antibiotic X 4357B,Concanamycin	Others	Others
	Concanamycin A is a macrolide antibiotic. It also is a specific inhibitor of vacuolar-type H+-ATPase (V-ATPase).
T10455	Bafilomycin B1 巴佛洛霉素 B1	Others	Others
	Bafilomycin B1, a macrolide antibiotic isolated from Streptomyces sp, acts as an inhibitor of K+-dependent ATPase of E. coli. It also inhibits Gram-positive bacteria and fungi.
T14831	Bryostatin 1	HIV Protease; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome
	Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein (Kis: 8.07 nM and 0.45 nM).
T36044	17-hydroxy Venturicidin A
	17-hydroxy Venturicidin A is a macrolide fungal metabolite originally isolated from Streptomyces. It has antibiotic activity against M. luteus, B. subtilis, and S. aureus and antifungal activity against V. dahlia, Fusarium, and C. tropicalis in a disc assay.
T38258	Phanerosporic Acid
	Phanerosporic acid is a fungal secondary metabolite originally isolated from P. chrysosporum that has antibacterial activity against B. cereus, B. subtilis, and E. coli and antifungal activity against S. cerevisiae, A. niger, O. ulmi, U. maydis, C. cucmerinum, C. cladosporioides, and B. cinerea.1 It has been used in the synthesis of macrolide derivatives.References1. Arnone, A., Assante, G., Nasini, G., et al. Phanerosporic acid, a β-resorcylate obtained from Phanerochaete chrysosporium. Phytoch...
T11233	Erythromycin thiocyanate	Antibacterial	Microbiology/Virology
	Erythromycin thiocyanate acts by binding to bacterial 50S ribosomal subunits and inhibits RNA-dependent protein synthesis by blockage of transpeptidation and/or translocation reactions, without affecting synthesis of nucleic acid .Erythromycin thiocyanate
T36417	Nargenicin Antibiotic 47444
	Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg/ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 μg/ml). [1] It dose-dependently inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE when used at concentrations of 0.00001-0.1 and 0.01-100 μg/mL, respectively. [2] In murine BV-2 microglial cells, nargenicin (...

天然产物

Cat.No: T0971

Synonym: Dirithromycinum,地红霉素,ASE 136,LY237216,Diritromicina,Dirithromycine

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T2481

Synonym: FK520,Immunomycin,子囊霉素,FR-900520

Target: Phosphatase, Others, Antibiotic, Parasite, Antifungal

Cat.No: T3607

Synonym: 吉他霉素,Kitasamycin,Leucomycin V,Turimycin

Target: Antibacterial, Antibiotic

Cat.No: T1032

Synonym: 红霉素,E-Mycin

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T5037

Synonym: Antibiotic SF-837,Turimycin P3,Medecamycin A1,Rubimycin,麦迪霉素,Platenomycin B1,Espinomycin A

Target: Antibacterial, Antibiotic

Cat.No: T3629

Synonym: ML-1709460,加米霉素

Target: Antibacterial, Antibiotic

Cat.No: T1151

Synonym: Roxl-150,罗红霉素,RU-28965

Target: ribosome, Antibacterial, Antibiotic

Erythromycin ethylsuccinate

Cat.No: T0474

Synonym: EES,琥乙红霉素

Target: ribosome, HIV Protease, Antibacterial, Antibiotic, Autophagy

Cat.No: T21495

Target: Others

Tylosin tartrate

Cat.No: T0861

Synonym: 酒石酸泰洛星,酒石酸泰乐菌素

Target: Antibacterial, Antibiotic

Azithromycin hydrate

Cat.No: T1419

Synonym: CP-62993 dihydrate,阿奇霉素二水物,Azithromycin dihydrate,阿奇霉素二水合物

Target: ribosome, Antibacterial, Antibiotic, Autophagy

Cat.No: T7148

Synonym: EN-141,交沙霉素

Target: Antibacterial, Antibiotic

Mycaminosyltylonolide

Cat.No: T67867

Target: Antibacterial

Cat.No: T1003

Synonym: Fradizine,Tylosin A,泰乐菌素,Tylosine,Tylocine

Target: Antibacterial, Antibiotic

Filipin complex

Cat.No: T11287

Target: Antifungal

Cat.No: T6194

Synonym: 非达米星,Tiacumicin B,OPT-80,Clostomicin B1,PAR-101

Target: Apoptosis, DNA/RNA Synthesis, Antibacterial, Antibiotic

Cat.No: T6062

Synonym: BFA,布雷非德菌素 A,Ascotoxin,Cyanein,Decumbin

Target: ATPase, Mitophagy, Antibiotic, Autophagy, HSV, CRISPR/Cas9

Erythromycin estolate

Cat.No: T15245

Synonym: Phtalic anhydride,ilosone

Target: Antibacterial

Cat.No: T6740

Synonym: 巴佛洛霉素A1,巴佛洛霉素 A1

Target: Apoptosis, Proton pump, Antibacterial, Antibiotic, Autophagy

Cat.No: T0819

Synonym: Espiramicin,螺旋霉素,Sequamycin,Rovamycin,Provamycin,Formacidine

Target: Antibacterial, Antibiotic, Parasite

Tacrolimus monohydrate

Cat.No: T20879

Synonym: FK-506,FR 900506,Prograf,FR900506,Tacrolimus hydrate,LCP-Tacro,他克莫司一水合物,FK 506

Target: Phosphatase, Others, Antibacterial, Antibiotic, Autophagy

Cat.No: T23505

Target: Others

Kitasamycin tartrate

Cat.No: T20779

Synonym: Leucomycin tartrate

Cat.No: T10582

Synonym: Treponemycin

Target: Others

Cat.No: T25622

Synonym: Bundlin A,Lankacidin C,Antibiotic T-2636 C,NSC 145118,Lankacidin

Cat.No: T14995

Synonym: X 4357B,刀豆素A,Antibiotic X 4357B,Concanamycin

Target: Others

Cat.No: T10455

Synonym: 巴佛洛霉素 B1

Target: Others

Cat.No: T14831

Target: HIV Protease, PKC

17-hydroxy Venturicidin A

Cat.No: T36044

Phanerosporic Acid

Cat.No: T38258

Erythromycin thiocyanate

Cat.No: T11233

Target: Antibacterial

Cat.No: T36417

Synonym: Antibiotic 47444

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