Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6617 |
Optovin
|
TRP/TRPV Channel | Membrane transporter/Ion channel |
Optovin 是可逆的光活化 TRPA1配体,可实现光介导的神经元兴奋。它通过与氧化还原敏感的半胱氨酸残基产生结构依赖性光化学反应激活 TRPA1。 | |||
T31409 |
DFHO
|
||
DFHO 是一种激发后可散发黄色荧光的 Corn 同源配体,用于活细胞中 RNA 的成像。 | |||
T18889 |
5-Aminofluorescein
5-氨基荧光素,5-AF |
Others | Others |
5-Aminofluorescein (5-AF) (5-AF) is a covalently-bound fluorescence marker conjugated with human serum albumin. It exhibits an excitation wavelength of 490 nm and an emission wavelength of 515 nm. | |||
T15025L |
CY5 triethylamine salt
CY5 triethylamine salt(146368-11-8 Free base) |
Others | Others |
CY5 triethylamine salt 是一种水溶性染料,激发光波长(nm):649,发射波长(nm):670。 | |||
T18991 |
Fluorescein-5-maleimide
N-(5-Fluoresceinyl)maleimide,荧光素-5-马来酰亚胺 |
Others | Others |
Fluorescein-5-maleimide (N-(5-Fluoresceinyl)maleimide) 是硫醇反应荧光染料 (λex=494 nm,λem=519 nm),可用于将荧光素与蛋白质缀合。 | |||
T9120 |
HBC
Benzeneacetonitrile, 4-cyano-α-[[4-[(2-hydroxyethyl)methylamino]phenyl]methylene]-,HBC 530 |
Others | Others |
HBC (HBC 530) 530 是绿色荧光蛋白 (GFP) 类荧光团的合成染料,具有结构刚性的电子受体和强电子供体。它能够用于 RNA 定位的检测。 | |||
T18891 |
5-TAMRA
5-羧基四甲基罗丹明,5-Carboxytetramethylrhodamine |
Others | Others |
5-TAMRA (5-Carboxytetramethylrhodamine) 能够产生明亮的、pH 不敏感的橙红色荧光 (λex=546 nm,λem=579 nm),有良好的光稳定性。 | |||
TD0106 |
IR-783
|
Others | Others |
IR-783 是一种七次甲基花青荧光探针,用于肿瘤细胞的体内成像。它分别显示 633/780 nm 的激发/发射值。 | |||
T18949L |
CY5-SE Ditriethylamine salt
CY5-SE Ditriethylamine salt(146368-14-1 Free base) |
Others | Others |
CY5-SE Ditriethylamine salt 是用于标记寡核苷酸,肽,蛋白质的氨基基团的反应染料。 激发波长 (nm): 649, 发射波长 (nm): 670 | |||
T14054 |
5-TAMRA-SE
5-羧基四甲基罗丹明琥珀酰亚胺酯,5-Carboxytetramethylrhodamine succinimidyl ester,5-TAMRA-NHS ester |
Others | Others |
5-TAMRA-SE 是一种胺反应性荧光剂。它的结合物能够产生一种 pH 不敏感的、明亮的橙红色荧光(Ex/Em~546/579 nm),具有良好的光稳定性。 | |||
T8836 |
CY5-SE triethylamine salt
Fluorolink Cy5 triethanolamine salt,Cy5-SE (triethylamine salt) |
Others | Others |
CY5-SE triethylamine salt (Fluorolink Cy5 triethanolamine salt) 是一种用于标记肽, 蛋白质, 寡核苷酸的氨基基团的反应染料 (Ex=649 nm; Em=670 nm)。 | |||
T40842 |
ER-Tracker Green
|
||
ER-Tracker Green (ERTG) 是一种细胞通透性活细胞染色剂,用于活细胞成像。ER-Tracker Green 激发波长为 504 nm,发射波长为 511 nm。 | |||
T18903 |
6-ROX
6-Carboxy-X-rhodamine,6-羧基-X-罗丹明 |
Others | Others |
6-ROX (6-Carboxy-X-rhodamine) 是寡核苷酸的荧光标记物,其激发波长和发射波长均为568nm。它是耦合至5-FAM 的受体,在FRET 成像中作为供体。 | |||
T39817 |
Msr-Ratio
Msr-green,Msr-Ratio |
Others | Others |
Msr-Ratio (Msr-green) (Msr-green) is a ratiometric fluorescent probe specifically designed for the detection of methionine sulfoxide reductase (MSR) activity. It has an excitation wavelength of 375 nm and an emission wavelength of 550 nm. This probe offers the ability to monitor the enzyme activity both in vitro and in live cells, making it a valuable tool for studying MSR function. | |||
T36343 |
Ac-LETD-AFC
|
||
Ac-LETD-AFC 是一种可被 caspase-8 特异性裂解的荧光底物,可通过荧光检测游离 AFC来量化 Caspase 活性。Ac-LETD-AFC 激发波长为 400 纳米,发射波长为 505 纳米。 | |||
T0802 |
Procaine hydrochloride
Novocaine HCl,Procaine HCl,盐酸普鲁卡因 |
Histone Demethylase; 5-HT Receptor; DNA/RNA Synthesis; Sodium Channel; NMDAR; AChR | Cell Cycle/Checkpoint; Chromatin/Epigenetic; DNA Damage/DNA Repair; GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience |
Procaine hydrochloride (Novocaine HCl) 是DNA 脱甲基剂,是一种苯甲酸衍生物,具有局部麻醉和抗心律失常特性。 | |||
T4054 |
Dantrolene sodium hemiheptahydrate
Dantrolene sodium hydrate,Dantrolene sodium salt,Dantrium,丹曲林钠五水合物,Sodium dantrolene |
Calcium Channel; Autophagy | Autophagy; Membrane transporter/Ion channel; Metabolism |
Dantrolene sodium hemiheptahydrate (Sodium dantrolene) 是一种钙通道蛋白抑制剂, 抑制钙离子从肌浆释放, 它是一种乙内酰脲衍生物和直接作用的骨骼肌松弛剂。 | |||
T15082 |
DDAO
|
Others | Others |
DDAO 是有潜在用途的近红外红色荧光探针,其激发波长 (600-650 nm) 和长发射波长 (λem = 656 nm)可以调节。它可用于不同酶活性的检测,如 β-半乳糖苷酶,羧酸酯酶 2,硫酸酯酶,蛋白质磷酸酶 2A,人白蛋白和酯酶。 | |||
T0018 |
Procainamide hydrochloride
Procapan,Procainamide HCl,Pronestyl,Procanbid,盐酸普鲁卡因胺 |
DNA Methyltransferase; Sodium Channel; AChR; Autophagy | Autophagy; Chromatin/Epigenetic; Membrane transporter/Ion channel; Neuroscience |
Procainamide hydrochloride (Procapan) 是一种用于研究心律失常的抗心律失常制剂。 | |||
T0077 |
Dantrolene sodium
Lapatinib ditosylate monohydrate,丹曲林钠,Dantrolene sodium salt |
Others; Calcium Channel | Membrane transporter/Ion channel; Metabolism; Others |
Dantrolene sodium (Lapatinib ditosylate monohydrate) salt 是一种骨骼肌松弛药,是一种钙通道蛋白抑制剂,可抑制钙离子从肌浆释放。 | |||
T1699 |
resorufin galactopyranoside
|
Others | Others |
resorufin galactopyranoside 是β-半乳糖苷酶的荧光底物,在被β-半乳糖苷酶酶切后,荧光部分间苯二酚被释放,其荧光可用于定量β-半乳糖糖苷酶的活性。它的激发光为570,发射光为580nm。 | |||
T6802 |
CFSE
5(6)-CFDA N-succinmidyl ester,Carboxyfluorescein succinimidyl ester,CFDA-SE,5(6)-羧基二乙酸荧光素琥珀酰亚胺酯,5(6)-Carboxyfluorescein diacetate succinimidyl ester |
Others | Others |
CFSE (CFDA-SE) 属于荧光染料,具有细胞膜渗透性。CFSE 可在活细胞内与胞内蛋白进行不可逆的结合,用于检测细胞增殖,标记的细胞呈绿色荧光,激发波长为 488 nm,发射波长为 518 nm。 | |||
T36352 |
Suc-Leu-Tyr-AMC
|
||
Suc-Leu-Tyr-AMC 是钙蛋白酶 I 和 II 以及木瓜蛋白酶(另一种半胱氨酸蛋白酶)的荧光底物,用于测量 20S 蛋白酶体的糜蛋白酶样肽酶活性(Ex-max:360 nm;Em-max:460 nm)。Suc-Leu-Tyr-AMC 也能被大肠杆菌的 Ti 蛋白酶裂解。 | |||
T22781L |
FFN 511 hydrochloride
FFN 511 hydrochloride(1004548-96-2 Free base) |
||
FFN 511 hydrochloride 是一种针对神经元囊泡单胺转运体 2 (VMA T2) 的荧光假神经递质 (FFNs)。FFN 511 hydrochloride 可抑制 5-羟色胺与含 VMA T2 的膜结合,可用于标记活体皮质-纹状体急性切片中的多巴胺能神经末梢。激发和发射最大值分别为 406 和 501 nm。 | |||
T14050 |
5-FAM
5-羧基荧光素,5-Carboxyfluorescein |
Others | Others |
5-FAM (5-Carboxyfluorescein) 是一种绿色荧光探针(Ex/Em 为 490 nm/520 nm),可用于肽,蛋白质和核苷酸的标记。 | |||
T19062 |
Sulforhodamine 101
磺基罗丹明101,磺基罗丹明 101,SR101 |
Others | Others |
Sulforhodamine 101 (SR101) 是一种两性罗丹明红色荧光染料 (excitation/emission: 586/605 nm),常用于神经元形态的研究,并作为星形胶质细胞的细胞类型选择性荧光标记物,在体内和切片制备中都有应用。 | |||
T36587 |
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt
|
Others | Others |
8-Aminopyrene-1,3,6-trisulfonic Acid sodium salt 是一种阴离子荧光染料,用作葡萄糖传感和检测其他糖类的报告分子。激发/发射光谱为 425/503 nm。 它可以在溶液中使用,也可以通过还原胺化连接醛官能化单体来固定,而不会显著改变荧光强度。 | |||
T41194 |
FFN 102 mesylate
|
Others | Others |
FFN 102 mesylate 是pH 响应型荧光假神经递质(FFN),作为选择性多巴胺转运蛋白(DAT)和VMAT2底物。FFN 102 mesylate 与38个中枢神经系统受体(包括多巴胺和血清素受体)无明显结合。它的Ex-max在pH 值5时为340 nm,在pH 值7.5时为370 nm,在pH 值为5和7.5时,Em-max为435 nm。 | |||
T23440 |
TC-N 22A
|
GluR | Neuroscience |
TC-N 22A 是一种作用力强的、可选择的、口服具有活性的、可以通过血脑屏障的 mGlu4 正向别构调节剂 (PAM)。TC-N 22A 在表达人 mGlu4 的 BHK 细胞中 EC50 表现为 9 nM。TC-N 22A 在激动和正向别构模型中对 mGlu 1、2、3、5 和 7 受体的活性表现很低 (EC50 >10 μM)。TC-N 22A 可以用于中枢神经系统疾病的研究。 | |||
T22043 |
BCATc Inhibitor 2
|
Others | Others |
BCATc Inhibitor 2 是选择性分支链氨基转移酶抑制剂,可用于神经退行性疾病的研究。能够抑制 rBCATc (IC50:0.2 μM),hBCATc (IC50:0.8 μM)、 rBCATm (IC50:3.0 μM)。其中BCATc 也称为 BCAT1,存在于细胞质基质中的亚型。 | |||
T20962 |
(S)-Baclofen
(+)-Baclofen,(L)-Baclofen |
||
(S)-Baclofen has effects on excitation in the ascending auditory pathway leading to it a potential reagent for the treatment of hyperactive auditory disorders such as hyperacusis and tinnitus. | |||
T18973 |
Di-8-ANEPPS
|
Others | Others |
Di-8-ANEPPS, a voltage-sensitive dye, demonstrates shifts in both its fluorescence excitation and emission spectra in response to changes in membrane potential (Vm). | |||
T71579 |
GOE-5438
|
||
GOE-5438 is a calcium antagonist that has been shown to inhibit the excitation and contraction of single cardiomyocytes. | |||
T41193 | FFN 270 | ||
FFN 270 is a fluorescent false neurotransmitter (FFN). Fluorescent substrate for NET and VMAT2. Labels noradrenergic neurons and their synaptic vesicles, and enables imaging of synaptic vesicle content release from specific axonal sitesin vivo. Selectively labels NA neurons over other monoamine and CNS targets. Exhibits two resolved absorption/excitation maxima depending on solvent pH (excitation maxima: 320 nm or 365 nm, emission maxima: 475 nm). | |||
T19053 |
Rhodamine 101 chloride
Rhodamine 640 chloride |
Others | Others |
Rhodamine 101 chloride is a bright fluorescent dye (excitation: 565 nm, emission: 595 nm). | |||
T34458 |
Ryanodol
|
||
Ryanodol is a complex diterpenoid that modulates intracellular calcium-ion release at ryanodine receptors, ion channels critical for skeletal and cardiac muscle excitation-contraction coupling and synaptic transmission. | |||
T39431 |
HKOCl-3
|
||
HKOCl-3 is a fluorescent probe characterized by its high sensitivity and selectivity for hypochlorous acid detection, featuring an excitation wavelength (Ex) of 490 nm and an emission wavelength (Em) of 527 nm. | |||
T19038 |
NIR-H2O2
|
Others | Others |
NIR-H2O2 is a cell-permeable near-infrared (NIR) fluorescent turn-on sensor. It responds to H2O2 with a large turn-on NIR fluorescence signal upon excitation in the NIR region. | |||
T33674 |
NIM-7
NIM7 |
||
NIM-7 is a fluorescent probe, allowing lipid droplets and lysosomes to be labelled simultaneously and with high specificity, being visualized readily through yellow and red fluorescence, using different excitation and detection channels. | |||
T31754 |
FD-1080
Heptamethine cyanine dye FD 1080,FD1080,Heptamethine cyanine dye FD1080,Heptamethine cyanine dye FD-1080 |
||
FD-1080 is a fluorophore with both excitation and emission in the NIR-II region for in vivo imaging. | |||
T71531 | Metamizil hydrochloride | ||
Metamizil hydrochloride is a cholinolytic agent -- an agent that blocks the transmission of excitation from cholinergic nerve fibers -- and an antagonist of the mediator acetylcholine. | |||
T39632 |
PB succiniMidyl ester
PB succiniMidyl ester,Ocean Blue, SE |
||
PB succiniMidyl ester (Ocean Blue, SE) is a fluorophore with the λ excitation/emission of ~405/455 nm. | |||
T78431 |
Ac-YVAD-AFC
|
||
Ac-YVAD-AFC为caspase-1特异性的荧光肽底物,具备激发波长400 nm及发射波长505 nm。 | |||
T18939 |
Cy2-SE (iodine)
CY2-SE,Cyanine2 Succinimidyl Ester |
Others | Others |
CY2-SE (Cyanine2 Succinimidyl Ester) is a dye for the labeling of amino-groups in oligonucleotides, peptides, and proteins (Excitation:492 nm, Emission: 510 nm). | |||
T37667 |
True Blue
|
||
True blue is a fluorescent neuronal retrograde tracer that labels the nucleus, nucleolus, cell body, proximal dendrites, and axons of neurons. It displays excitation/emission maxima of 373/404 nm, respectively. | |||
T41196 |
Phalloidin-FITC
|
||
Phalloidin-FITC is a green fluorescent cytoskeleton stain. Binds and labels F-actin. For most fluorescent imaging applications, cells should be fixed and permeablilized. Excitation/emission maxima λ ~496/516 nm. | |||
T71021 |
Fendiline
|
||
Fendiline is a coronary vasodilator that inhibits calcium function in muscle cells in excitation-contraction coupling; proposed as an antiarrhythmic and antianginal agent. | |||
T19041 |
Hoechst S 769121
Nuclear yellow |
Others | Others |
Hoechst S 769121 (Nuclear yellow) is a fluorescence dye that can bound to DNA (excitation/emission maxima ~335/495 nm). | |||
TD0029 |
Super Fluor 750
|
||
Super Fluor 750 dye is a bright, near-IR–fluorescent dye with excitation ideally suited for the 633 nm laser line or dye-pumped laser excitation. Super Fluor 750 dye is pH-insensitive over a wide molar range, helping ensure that you get stable signals in | |||
T41208 |
NB-caged Tyrosine hydrochloride
ONBY,NB-caged Tyrosine hydrochloride |
||
NB-caged Tyrosine hydrochloride is a L-Tyrosine caged with photosensitiveortho-nitrobenzyl side chain. Rapidly releases tyrosine when photolyzed (300-350 nm excitation). Is readily incorporated intoE.coliproteins via inclusion in growth media. |