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Search Results for " bronchodilator "

58

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T4983	Isoetharine mesylate salt Isoetarine mesilate,异丙肾上腺素甲磺酸盐	Others; Adrenergic Receptor	GPCR/G Protein; Neuroscience; Others
	Isoetharine mesylate salt (Isoetarine mesilate) 是一种 β-肾上腺素能受体激动剂。它还是能够上调 CYP450 表达的孕烷 X 受体(PXR) 激活剂。
T1056	Isoprenaline hydrochloride NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl,盐酸异丙肾上腺素	PI3K; Endogenous Metabolite; Adrenergic Receptor; PDE	GPCR/G Protein; Metabolism; Neuroscience; PI3K/Akt/mTOR signaling
	Isoprenaline hydrochloride (NCI-c55630) 是非选择性的β-肾上腺素能受体激动剂，有支气管扩张剂，外周血管扩张剂和心脏刺激活性。
T1584	Terbutaline Sulfate Terbutaline hemisulfate,硫酸叔丁宁按,硫酸特布他林	Antibacterial; Adrenergic Receptor; Antibiotic	GPCR/G Protein; Microbiology/Virology; Neuroscience
	Terbutaline Sulfate (Terbutaline hemisulfate) 是一种具有口服活性的 β2-肾上腺素能受体激动剂，是班布特罗的活性代谢物。它可研究哮喘。
T21389	Enprofylline Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum,恩丙茶碱	Others	Others
	Enprofylline (Enprofilina) 是具有选择性的 A2B 受体竞争性拮抗剂 (Ki:7 μM) ，也是磷酸二酯酶抑制剂。它可用于研究哮喘、慢性阻塞性肺疾病。
T17284	Zardaverine BY 290,B 84290	PDE	Metabolism
	Zardaverine (BY 290) 是一种可口服且具有选择性和有效性的 PDE3/4 抑制剂，具有支气管扩张活性和抗肝癌活性。Zardaverine 在血小板中的作用是通过PDE III同工酶介导，可用于研究急性肾衰竭呵呵慢性气流阻塞。
T27594	Ilmetropium iodide	Others	Others
	Ilmetropium iodide 是一种支气管扩张剂。
T30232	AWD 12-281 GSK 842470,GSK-842470,AWD12-281,AWD-12-281,GW 842470	PDE	Metabolism
	AWD 12-281 是一种选择性磷酸二酯酶 4 (PDE4) 抑制剂，具有抗炎活性和支气管扩张活性，用于研究慢性阻塞性肺疾病（COPD）。
T6896	Tolimidone 托利咪酮,NSC 314335,MLR-1023,CP-26154	Src	Angiogenesis; Tyrosine Kinase/Adaptors
	Tolimidone (NSC 314335) 是选择性的 Lyn kinase 变构激活剂，其 EC50=63 nM。
T9817	Isbufylline	Others	Others
	Isbufylline 具有显着的抗炎作用和支气管扩张剂活性。
T0248	Clorprenaline hydrochloride 盐酸氯丙那林,Clorprenaline HCl,NSC 334693	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Clorprenaline hydrochloride (Clorprenaline HCl) 是 β2-肾上腺素受体激动剂，与支气管扩张有关，可用于研究哮喘。
T35048	Verofylline CK 0383,Verofilina,CK-0383,Verofyllinum,CK0383	PDE	Metabolism
	Verofylline (Verofyllinum) 是一种可口服的长效多效取代甲基黄嘌呤支气管扩张剂，对 PDE4 具有抑制作用，可用于治疗哮喘疾病研究肥胖症。
T22245	Arformoterol Tartrate (R,R)-Formoterol tartrate,酒石酸福莫特罗	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Arformoterol Tartrate ((R,R)-Formoterol tartrate) 是一种长效 β2-肾上腺素能受体 (β2-AR) 激动剂，Kd=2.9 nM。它是一种 Formoterol 的 (R,R)-对映异构体，可用于慢性阻塞性肺疾病 (COPD) 的研究。
T21673	N-Isopropylnoratropine	Others	Others
	N-Isopropylnoratropine 是一种去甲托品衍生物，是生产异丙托溴铵(ipratropium) 的中间体，异丙托溴铵是一种通过抗胆碱能途径产生的阿托品样支气管扩张药。它用于检查异丙托溴铵的稳定性。
T1179	Tiotropium bromide Tiopropium,噻托溴铵,BA679 BR	AChR	Neuroscience
	Tiotropium bromide (BA679 BR) 是一种毒蕈碱乙酰胆碱受体拮抗剂，可阻断乙酰胆碱配体的结合。
T1139	Salbutamol Albuterol,沙丁胺醇,AH-3365	Adrenergic Receptor	GPCR/G Protein; Neuroscience
	Salbutamol (Albuterol) 是短效的 β2 肾上腺素受体激动剂，用于哮喘和慢性阻塞性肺疾病(COPD) 引发的支气管痉挛的研究。
T6707	Tiotropium Bromide hydrate BA-679 BR hydrate,BA 679BR,噻托溴铵一水合物	AChR	Neuroscience
	Tiotropium Bromide hydrate (BA-679 BR hydrate) 是长效的毒蕈碱受体拮抗剂，可用于治疗慢性阻塞性气道疾病 (COPD)。
T26236	Sulfonterol Sulfonterolum
	Sulfonterol is a Bronchodilator.
T25161	Bitolterol mesylate
	Bitolterol mesylate is a Bronchodilator.
T31684	Etafedrine HCl Novedrin hydrochloride,Nethamine,Nethamine hydrochloride,Etafedrine hydrochloride,Menetyl,Novedrin
	Etafedrine HCl, named Nethaprin, is a long-acting bronchodilator.
T34913	TR4161 TR 4161,TR-4161
	TR4161 is a prostaglandin bronchodilator of low tracheobronchial irritancy.
T34238	R 836 R836,R-836
	R 836 has bronchodilator effects.
T25153	BIIK-0277 Levalbuterol related compound E RS,BIIK 0277
	BIIK-0277 (Levalbuterol Related Compound E) is a β2-adrenoceptor agonist, bronchodilator, and tocolytic.
T19322	FKK	Others	Others
	FKK is an indazole derivative and also a novel bronchodilator.
T25499	Hexoprenaline
	Hexoprenaline is a stimulant of adrenergic beta 2 receptors used as a bronchodilator, antiasthmatic agent, and tocolytic agent.
T25398	Ethylnorepinephrine hydrochloride Butanefrine hydrochloride,Bronkephrine
	Ethylnorepinephrine hydrochloride is a unique bronchodilator.
T15498	HOKU-81 4-Hydroxytulobuterol	Others	Others
	HOKU-81is a new bronchodilator and is one of the metabolites of tulobuterol.
T27179	Diniprofylline Coreverum
	Diniprofylline, a phosphodiesterase inhibitor, has been used as a peripheral nervous system agent, a bronchodilator agent, and an anti-asthamtic agent.
T30265	Navafenterol saccharinate AZD8871 saccharinate,LAS-191351 saccharinate,LAS191351 saccharinate,AZD-8871 saccharinate
	AZD-8871 saccharinate is a dual-acting bronchodilator which may be useful in the treatment of Chronic Obstructive Pulmonary Disease (COPD).
T68083	ibuterol
	Ibuterol 是一种支气管扩张剂，是terbutaline 的前药
T25963	Pirbuterol hydrochloride
	Pirbuterol hydrochloride is a bronchodilator.
T70797	AQ-RA 721
	AQ-RA 721 is a selective muscarinic antagonist with high affinity for M1- and M3-receptors. AQ-RA 721 may be used as a bronchodilator.
T69697	Dioxethedrin HCl
	Dioxethedrin HCl is the ephedrine derivative. It is the beta-adrenergic agonist. As a bronchodilator and sympathomimetic agent is was used in antitussive syrup Bexol.
T27552	Hoquizil hydrochloride Hoquizil HCl,CP-14,185-1,CP-14185-1
	Hoquizil hydrochloride is a new bronchodilator with oral activity.
T36772	11-deoxy Prostaglandin F1β 11-deoxy Prostaglandin F1β
	11-deoxy PGF1β is a synthetic analog of PGF1β. In contrast to PGF2α and PGF1α, 11-deoxy PGF1β exhibits vasodepressor and bronchodilator activities in guinea pigs at a dose of 500 μg/kg.
T70854	Protokylol hydrochloride
	Protokylol hydrochloride is the salt form of Protokylol (free base) (Asmetil, Caytine, Palison, Ventaire), a β-adrenergic receptor agonist used as a bronchodilator in Europe and the United States. It is methylenedioxyphenyl-isoproterenol.
T21352	Salmefamol AHR-3929,AHR3929,AHR 3929
	Salmefamol is a beta-adrenergic agonist. It may also be used as a bronchodilator.
T31678	Espatropate UK-88060
	Espatropate is a bronchodilator with antimuscarinic activity.
T30240	AY 22093 AY-22,093
	AY 22093 is a prostanoic acid derivative with bronchodilator activity.
T68272	Batefenterol Succinate
	Batefenterol Succinate is a first-in-class inhaled bifunctional bronchodilator possessing muscarinic receptor antagonist and β2-adrenoceptor agonist properties.
T60502	Isoetharine hydrochloride
	Isoetharine (hydrochloride) (compound I) 是一种选择性和口服活性的短效β-肾上腺能受体激动剂，广泛用作吸入治疗研究中的支气管扩张剂。
T71575	Dioxifedrine
	Dioxifedrine is a beta-2 -adrenergic agonist with bronchodilator activity.
T22331	Fenoterol hydrobromide 非诺特罗氢溴酸盐,氢溴酸非诺特罗,Phenoterol hydrobromide	Others	Others
	Fenoterol hydrobromide, the hydrobromide salt of fenoterol, is a β2 adrenoreceptor agonist with bronchodilator activity.
T13899	Spirofylline	Others	Others
	Spirofylline is an agent of bronchodilator, has the potential for asthma and bronchitis and emphysema treatment.
T68312	Etanterol
	Etanterol is a phenethanolamine derivative and a β2 adrenoceptor agonist that was undergoing phase II trials in Italy as a bronchodilator with Valeas.
T4983L	Isoetharine Isoetarine,Bronkosol,Bronkometer,Etyprenalinum
	Isoetharine is a selective agonist of β2-adrenergic receptor used as a bronchodilator for emphysema, bronchitis, and asthma.
T16417	Oxitropium Bromide	AChR	Neuroscience
	Oxitropium bromide is a mAChR antagonist. It is used as an anticholinergic bronchodilator drug for the treatment of asthma and chronic obstructive pulmonary disease.
T71017	Picumeterol fumarate
	Picumeterol fumarate is a potent and selective beta2-adrenoceptor agonist that acts as a bronchodilator.
T69491	(E/Z)-Ensifentrine
	(E/Z)-Ensifentrine is a potent and selective PDE3/4 inhibitor. (E/Z)-Ensifentrine acts as a long-acting inhibitor of the phosphodiesterase enzymes PDE-3 and PDE-4, producing both bronchodilator and antiinflammatory effects. It is being developed by Verona Pharma as a potential treatment for asthma and hay fever, and is currently in clinical trials.
T21411L	Isoproterenol bitartrate
	Isoproterenol bitartrate is a beta-sympathomimetic and an isopropyl analog of Epinephrine, which acts on the heart, bronchi, skeletal muscle, and alimentary tract. It is used mainly as a bronchodilator and heart stimulant.
T70867	Soterenol
	Soterenol is an adrenergic beta-2 agonist used as bronchodilator and has a number of gastrointestinal side effects.

化合物

Isoetharine mesylate salt

Cat.No: T4983

Synonym: Isoetarine mesilate,异丙肾上腺素甲磺酸盐

Target: Others, Adrenergic Receptor

Isoprenaline hydrochloride

Cat.No: T1056

Synonym: NCI-c55630,Isoproterenol hydrochloride,Isoprenaline HCl,盐酸异丙肾上腺素

Target: PI3K, Endogenous Metabolite, Adrenergic Receptor, PDE

Terbutaline Sulfate

Cat.No: T1584

Synonym: Terbutaline hemisulfate,硫酸叔丁宁按,硫酸特布他林

Target: Antibacterial, Adrenergic Receptor, Antibiotic

Cat.No: T21389

Synonym: Enprofilina,3-propylxanthine,3-n-Propylxanthine,Enprofyllinum,恩丙茶碱

Target: Others

Cat.No: T17284

Synonym: BY 290,B 84290

Target: PDE

Ilmetropium iodide

Cat.No: T27594

Target: Others

Cat.No: T30232

Synonym: GSK 842470,GSK-842470,AWD12-281,AWD-12-281,GW 842470

Target: PDE

Cat.No: T6896

Synonym: 托利咪酮,NSC 314335,MLR-1023,CP-26154

Target: Src

Cat.No: T9817

Target: Others

Clorprenaline hydrochloride

Cat.No: T0248

Synonym: 盐酸氯丙那林,Clorprenaline HCl,NSC 334693

Target: Adrenergic Receptor

Cat.No: T35048

Synonym: CK 0383,Verofilina,CK-0383,Verofyllinum,CK0383

Target: PDE

Arformoterol Tartrate

Cat.No: T22245

Synonym: (R,R)-Formoterol tartrate,酒石酸福莫特罗

Target: Adrenergic Receptor

N-Isopropylnoratropine

Cat.No: T21673

Target: Others

Tiotropium bromide

Cat.No: T1179

Synonym: Tiopropium,噻托溴铵,BA679 BR

Target: AChR

Cat.No: T1139

Synonym: Albuterol,沙丁胺醇,AH-3365

Target: Adrenergic Receptor

Tiotropium Bromide hydrate

Cat.No: T6707

Synonym: BA-679 BR hydrate,BA 679BR,噻托溴铵一水合物

Target: AChR

Cat.No: T26236

Synonym: Sulfonterolum

Bitolterol mesylate

Cat.No: T25161

Cat.No: T31684

Synonym: Novedrin hydrochloride,Nethamine,Nethamine hydrochloride,Etafedrine hydrochloride,Menetyl,Novedrin

Cat.No: T34913

Synonym: TR 4161,TR-4161

Cat.No: T34238

Synonym: R836,R-836

Cat.No: T25153

Synonym: Levalbuterol related compound E RS,BIIK 0277

Cat.No: T19322

Target: Others

Cat.No: T25499

Ethylnorepinephrine hydrochloride

Cat.No: T25398

Synonym: Butanefrine hydrochloride,Bronkephrine

Cat.No: T15498

Synonym: 4-Hydroxytulobuterol

Target: Others

Cat.No: T27179

Synonym: Coreverum

Navafenterol saccharinate

Cat.No: T30265

Synonym: AZD8871 saccharinate,LAS-191351 saccharinate,LAS191351 saccharinate,AZD-8871 saccharinate

Cat.No: T68083

Pirbuterol hydrochloride

Cat.No: T25963

Cat.No: T70797

Dioxethedrin HCl

Cat.No: T69697

Hoquizil hydrochloride

Cat.No: T27552

Synonym: Hoquizil HCl,CP-14,185-1,CP-14185-1

11-deoxy Prostaglandin F1β

Cat.No: T36772

Synonym: 11-deoxy Prostaglandin F1β

Protokylol hydrochloride

Cat.No: T70854

Cat.No: T21352

Synonym: AHR-3929,AHR3929,AHR 3929

Cat.No: T31678

Synonym: UK-88060

Cat.No: T30240

Synonym: AY-22,093

Batefenterol Succinate

Cat.No: T68272

Isoetharine hydrochloride

Cat.No: T60502

Cat.No: T71575

Fenoterol hydrobromide

Cat.No: T22331

Synonym: 非诺特罗氢溴酸盐,氢溴酸非诺特罗,Phenoterol hydrobromide

Target: Others

Cat.No: T13899

Target: Others

Cat.No: T68312

Cat.No: T4983L

Synonym: Isoetarine,Bronkosol,Bronkometer,Etyprenalinum

Oxitropium Bromide

Cat.No: T16417

Target: AChR

Picumeterol fumarate

Cat.No: T71017

(E/Z)-Ensifentrine

Cat.No: T69491

Isoproterenol bitartrate

Cat.No: T21411L

Cat.No: T70867

Cat. No.	Product Name	Target	Signaling Pathways
TN1490	Chrysoeriol	ERK; p38 MAPK; Akt	Cytoskeletal Signaling; MAPK; PI3K/Akt/mTOR signaling
	Chrysoeriol 是一种天然黄酮，可从热带植物Coronopus didymus 中提取获得，具有强大的抗氧化功能，能够抑制脂质的过氧化。
T0625	Theobromine 3, 7-Dimethylxanthine,可可碱,3,7-Dimethylxanthine	Endogenous Metabolite; PDE; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Theobromine (3,7-Dimethylxanthine) 是在可可豆中发现的一种甲基黄嘌呤，抑制腺苷受体 A1 信号传导，用作支气管扩张剂和血管扩张剂。
TN1641	(-)-Fenchone	Others; Antioxidant; Antifungal	Microbiology/Virology; Others; oxidation-reduction
	(-)-Fenchone 是一种双环单萜类化合物，广泛分布于植物中，可从Foeniculum vulgare 和Peumus boldus 中提取。(-)-Fenchone 具有广泛的生物活性，包括抗氧化，伤口愈合，止泻，抗真菌，抗伤害感受和支气管扩张剂活性。(-)-Fenchone 是一种潜在的抗肿瘤化合物。
T5940	Proxyphylline 羟丙茶碱,7-(2-Hydroxypropyl)theophylline	PDE; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Proxyphylline (7-(2-Hydroxypropyl)theophylline) 是甲基黄嘌呤衍生物，可用作心脏活化剂、血管扩张剂和支气管扩张剂。
T0892	Diphylline 二羟丙茶碱,Dyphylline,Diprophylline	PDE; Adenosine Receptor	GPCR/G Protein; Metabolism; Neuroscience
	Diphylline (Diprophylline) 是一种A1/A2腺苷受体拮抗剂，也是环状核苷酸磷酸二酯酶抑制剂。它是一种黄嘌呤衍生物，具有支气管扩张和血管扩张作用，有用于治疗慢性支气管炎和肺气肿的潜力。
TN4303	Isokaempferide	ATPase; Potassium Channel; Calcium Channel; TNF; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Metabolism
	Isokaempferide shows hepatoprotective, antiproliferative, and anti-inflammatory effects, the anti-inflammatory effects can be explained, at least in part, by reducing neutrophil degranulation, myeloperoxidase activity, mediators as well as TNF-alpha secretion. Isokaempferide is used as a bronchodilator, can induce relaxation of guinea-pig isolated trachea.

天然产物

Cat.No: TN1490

Target: ERK, p38 MAPK, Akt

Cat.No: T0625

Synonym: 3, 7-Dimethylxanthine,可可碱,3,7-Dimethylxanthine

Target: Endogenous Metabolite, PDE, Adenosine Receptor

Cat.No: TN1641

Target: Others, Antioxidant, Antifungal

Cat.No: T5940

Synonym: 羟丙茶碱,7-(2-Hydroxypropyl)theophylline

Target: PDE, Adenosine Receptor

Cat.No: T0892

Synonym: 二羟丙茶碱,Dyphylline,Diprophylline

Target: PDE, Adenosine Receptor

Cat.No: TN4303

Target: ATPase, Potassium Channel, Calcium Channel, TNF, Prostaglandin Receptor

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