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Search Results for " vastatin "

Targets Recommended: Drug Metabolite

81

抑制剂 & 化合物

5

天然产物

1

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
TQ0045	2-Hydroxy atorvastatin calcium salt	Drug Metabolite	Metabolism
	2-Hydroxy atorvastatin calcium salt 是 Atorvastatin 钙盐的羟基代谢物，Atorvastatin 是一种有效的 HMG-CoA 还原酶抑制剂 (IC50 = 8 nM)。
T12652	(Rac)-5-Keto Fluvastatin 5-Ketofluvastatin,3-Hydroxy-5-Keto Fluvastatin,rac 5-Keto Fluvastatin	Others	Others
	(Rac)-5-Keto Fluvastatin (rac 5-Keto Fluvastatin) 是 Fluvastatin 的杂质，Fluvastatin 是一种 HMG-CoA 还原酶的抑制剂。
T1487	Fluvastatin sodium XU 62320 sodium,XU-62-320,氟伐他汀钠,Fluvastatin sodium salt	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Fluvastatin sodium (Fluvastatin sodium salt) salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂，IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激，是一种常用的降胆固醇剂。
T21405	Fluvastatin Canef,XU-62320,Vastin,Cranoc,Lescol	HMG-CoA Reductase	Metabolism
	Fluvastatin (XU-62320) 是一种具有高效性和竞争性的 HMG-CoA 还原酶抑制剂（IC50 ：8 nM），可通过依赖 Nrf2 通路抑制血管平滑肌细胞免受氧化应激，用于降低血浆胆固醇水平和预防心血管疾病。
T12490	Pitavastatin lactone	Others	Others
	Pitavastatin lactone 是 Pitavastatin 在人体中的主要代谢产物。Pitavastatin 是 HMG-CoA 还原酶竞争性抑制剂。
T20887	Atorvastatin Sodium Lipitor	LDL; Aquaporin; HMG-CoA Reductase	Membrane transporter/Ion channel; Metabolism
	Atorvastatin Sodium (Lipitor) 是一种HMG-CoA 还原酶的竞争性抑制剂，增加肝细胞上低密度脂蛋白（LDL）受体的表达。Atorvastatin sodium 处理抑制水汽蛋白4来减轻缺血性脑水肿。
T10324	Anhydrosimvastatin Dehydro simvastatin,脱水辛伐他汀	HMG-CoA Reductase	Metabolism
	Anhydrosimvastatin (Dehydro simvastatin) 是 Simvastatin 的一种杂质。其中Simvastatin 是竞争性的 HMG-CoA 还原酶抑制剂。
T14342	Atorvastatin lactone	HMG-CoA Reductase	Metabolism
	Atorvastatin lactone 是一种 Atorvastatin 的前药。其中 Atorvastatin 是口服具有活力的 3- 羟基 -3- 甲基戊二酰辅酶 A 还原酶抑制剂。
T24865	Tenivastatin L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid	ROS; HMG-CoA Reductase	Immunology/Inflammation; Metabolism
	Tenivastatin (Simvastatin acid) 是一种抗高脂血症的 HMG-CoA 还原酶抑制剂，抑制活性氧 (ROS) 产生，可用于研究原发性高脂血症。
T25285	Dalvastatin RG-12561,RG 12561,RG12561	HMG-CoA Reductase	Metabolism
	Dalvastatin (RG-12561) 是一种可口服的 HMG-CoA 还原酶和降胆固醇合成的抑制剂。Dalvastatin 竞争性地抑制大鼠肝脏HMG-CoA还原酶，IC50值为3.4 nmol / l。 Dalvastatin 在在大鼠实验中，抑制肝切片中的胆固醇生物合成，ED50值为0.9。
T13131	Tert-Buthyl Pitavastatin	HMG-CoA Reductase	Metabolism
	tert-Buthyl Pitavastatin 是 Pitavastatin 的代谢产物。其中Pitavastatin 是HMG-CoA 还原酶抑制剂。
T2534	Pitavastatin calcium P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,匹伐他汀钙,NK-104	Apoptosis; Mitophagy; Endogenous Metabolite; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Pitavastatin calcium (NK-104) 是一种羟甲基戊二酰-CoA 还原酶抑制剂。它在 HepG2 细胞中抑制乙酸合成胆固醇的IC50为 5.8 nM。它是高效的肝细胞低密度脂蛋白胆固醇受体诱导剂。具有抗癌活性。
T1510	Rosuvastatin calcium ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙	Potassium Channel; HMG-CoA Reductase; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Rosuvastatin calcium (ZD4522) 是肝羟甲基戊二酰辅酶 A 还原酶的选择性和竞争性抑制剂，具有抗血脂活性。它降低成熟 hERG 的表达以及热休克蛋白 70 与 hERG 蛋白的相互作用，还降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流，延迟心脏复极化，来延长动作电位持续时间和校正 QT 间期间隔。
T25276	Crilvastatin PMD387,PMD 387,PMD-387	HMG-CoA Reductase	Metabolism
	Crilvastatin (PMD 387) 是一种新型非竞争性羟甲基戊二酰辅酶 A 还原酶抑制剂，具有降胆固醇活性，可抑制遗传性高胆固醇血症大鼠的胆固醇吸收。
T1676	Rosuvastatin 罗伐他汀,ZD 4522,瑞舒伐他汀	Potassium Channel; HMG-CoA Reductase; Autophagy	Autophagy; Membrane transporter/Ion channel; Metabolism
	Rosuvastatin (ZD 4522) 是一种抗血脂药，可竞争性抑制羟甲基戊二酰辅酶 A 还原酶，用于降低血浆胆固醇水平和预防心血管疾病。它降低低密度脂蛋白胆固醇、甘油三酯和 C-反应蛋白水平。它阻断人类醚-a-go-go 相关基因电流，IC50为 195 nM，延迟心脏复极化，延长动作电位持续时间和校正 QT 间期间隔。
T3116	Atorvastatin hemicalcium salt Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,阿托伐他汀钙,Sortis	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Atorvastatin hemicalcium salt (Atorvastatin Calcium) 是一种口服有效的 HMG-CoA 还原酶抑制剂，可用作降低胆固醇的药物。它抑制人 SV-SMC 增殖和侵袭，IC50分别为 0.39 μM 和 2.39 μM。
T19918	Lovastatin hydroxy acid sodium 6-α-Methylcompactin sodium,Lovastatin Na,Lovastatin Sodium,Mevinolin sodium
	Lovastatin Sodium is an HMG-CoA reductase inhibitor.
T72101	Atorvastatin hemicalcium trihydrate 阿托伐他汀半钙三水合物,阿托他伐汀半钙三水合物
	Atorvastatin hemicalcium trihydrate 是一种具有口服活性的 HMG-CoA 还原酶抑制剂，具有有效降低血脂的能力。Atorvastatin hemicalcium trihydrate 以 IC50值分别为 0.39 μM 和 2.39 μM 来抑制人 SV-SMC 细胞的增殖和侵袭。
T40913	3α-Hydroxy pravastatin sodium
	3α-Hydroxy pravastatin sodium, the primary metabolite of Pravastatin, is a potent competitive inhibitor of HMG-CoA reductase.
T10402	Atorvastatin Epoxy Tetrahydrofuran Impurity	Others	Others
	Atorvastatin Epoxy Tetrahydrofuran Impurity is an impurity isolated oxidative degradation products of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor.
T12283	O-Methyl Atorvastatin hemicalcium	Others	Others
	O-Methyl Atorvastatin is an impurity of Atorvastatin that is an orally active inhibitor of 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) reductase, has the ability to effectively decrease blood lipids.
T10400	Atorvastatin acetonide tert-butyl ester	Others	Others
	Atorvastatin acetonide tert-butyl ester is a useful pharmaceutical intermediate in the preparation of Atorvastatin salts. Atorvastatin is an HMG-CoA reductase inhibitor.
T10120	3-Oxo Atorvastatin	Others	Others
	3-Oxo Atorvastatin is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T71492	Atorvastatin strontium
	Atorvastatin strontium is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia.
T10401	Atorvastatin acetonide	Others	Others
	Atorvastatin acetonide is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T10235	Acetyllovastatin	Others	Others
	Acetyllovastatin (acetate of Lovastatin) presents a moderate inhibitory effect against the acetylcholinesterase (IC50: 79 μg/mL). Lovastatin displays antifungal activity and suppresses the proliferation of a number of transformed cell lines.
T10126	(3R,5R)-Rosuvastatin	Others	Others
	(3R,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).
T38249	2-Hydroxy atorvastatin lactone
	2-Hydroxy atorvastatin lactone, a metabolite of Atorvastatin, is an orally active HMG-CoA reductase inhibitor that efficiently reduces blood lipids [1][2].
T15099	Desfluoro-atorvastatin	Others	Others
	Desfluoro-atorvastatin is an Atorvastatin impurity. Atorvastatin is an orally active inhibitor of HMG-CoA reductase. It has the ability to effectively decrease blood lipids.
T81257	Rosuvastatin zinc salt Rosuvastatin zinc
	Rosuvastatin zinc salt (Rosuvastatin zinc)，为Rosuvastatin的含锌盐形态，属于HMG-CoA还原酶抑制剂类药物，常用于动脉粥样硬化的研究领域。
T19551	Rosuvastatin D6 Calcium	Others	Others
	Rosuvastatin D6 Calcium is deuterium labeled Rosuvastatin, which is a competitive HMG-CoA reductase inhibitor(IC50 of 11 nM).
T11306	Fluvastatin D6 sodium XU 62-320 (D6)	Others	Others
	Fluvastatin sodium is a first fully synthetic, competitive HMG-CoA reductase inhibitor with an IC50 of 8 nM.Fluvastatin D6 sodium is deuterium labeled Fluvastatin sodium.
T10129	(3S,5R)-Fluvastatin sodium (3S,5R)-XU 62-320	Others	Others
	(3S,5R)-Fluvastatin sodium is the (3S,5R)-enantiomer of Fluvastatin. Fluvastatin is a first fully synthetic, competitive HMG-CoA reductase inhibitor (IC50: 8 nM). Fluvastatin protects vascular smooth muscle cells against oxidative stress through the Nrf2-
T10132	(3S,5S)-Pitavastatin calcium	Others	Others
	(3S,5S)-Pitavastatin calcium is the 3-epimer of Pitavastatin which is a potent HMG-CoA reductase inhibitor.
T69178	Rosuvastatin lactone
	Rosuvastatin lactone is the lactone form of the HMG-CoA reductase inhibitor rosuvastatin. It is found in vivo following rosuvastatin administration. Rosuvastatin lactone is an inhibitor of the cytochrome P450 (CYP) isoforms CYP2C9.1 and CYP2C9.3 (IC50s = 8.52 and 4.1 µM, respectively).
T63430	Rosuvastatin Sodium
	Rosuvastatin Sodium 是竞争性HMG-CoA 还原酶 (HMGCR) 抑制剂 (IC50: 11 nM)，能够有效阻断hERG 电流 (IC50: 195 nM)。Rosuvastatin Sodium 可以有效减少低密度脂蛋白 (LDL) 胆固醇，甘油三酯和 C- 反应蛋白水平。Rosuvastatin Sodium 能够减少成熟 hERG 的表达，并抑制及热休克蛋白 70 (Hsp70) 与 hERG 蛋白的相互作用。
T38920	Atrovastatin-PEG3-FITC Atrovastatin-PEG3-FITC
	Atrovastatin-PEG3-FITC (compound S31) functions as a ligand in fluorescence anisotropy assay. Its primary role is as a KRAS-PDEδ interaction inhibitor.
T71705	Glenvastatin
	Glenvastatin 是一种HMG-CoA 还原酶抑制剂，具有吡啶基结构。
T15127	Difluoro atorvastatin Fluoroatorvastatin	Others	Others
	Difluoro atorvastatin is an Atorvastatin impurity. Atorvastatin is an orally active HMG-CoA reductase inhibitor and it has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation and invasion (IC50s: 0.39 μM and
TMIH-0242	Fluvastatin-d6 Sodium Salt
	Fluvastatin-d6 Sodium Salt 是 Fluvastatin Sodium Salt 的氘代化合物。Fluvastatin Sodium Salt 的 CAS 号为 93957-55-2。Fluvastatin sodium salt 是羟甲基戊二酰辅酶 A 还原酶的竞争性抑制剂，IC50为 8 nM。它通过依赖 Nrf2 的抗氧化通路保护血管平滑肌细胞免受氧化应激，是一种常用的降胆固醇剂。
T12488	Pitavastatin D4 NK-104 D4	Others	Others
	Pitavastatin D4 is deuterium labeled Pitavastatin. Pitavastatin is a potent inhibitor of HMG-CoA reductase.
T10127	(3R,5S)-Atorvastatin sodium	Others	Others
	(3R,5S)-Atorvastatin sodium is an impurity of Atorvastatin. Atorvastatin is an HMG-CoA reductase inhibitor and has the ability to effectively decrease blood lipids.
T71560	Atorvastatin magnesium trihydrate
	Atorvastatin magnesium trihydrate is used primarily for lowering blood cholesterol and for prevention of events associated with cardiovascular disease. Like all statins, atorvastatin works by inhibiting HMG-CoA reductase, an enzyme found in liver tissue that plays a key role in production of cholesterol in the body.Atorvastatin is also used for the treatment of dyslipidemia.
T21080	(3S,5S)-Atorvastatin ent-Atorvastatin,3S,5S-Atorvastatin,(3S,5S)-阿托伐他汀
	ent-Atorvastatin is a selective and competitive inhibitor of HMGCR (HMG-CoA reductase).
T39036	(3R,5S)-Fluvastatin (3R,5S)-Fluvastatin,(3R,5S)-XU 62-320 free acid
	(3R,5S)-Fluvastatin, the 3R,5S-isomer of Fluvastatin (XU 62-320 free acid), stands as the inaugural fully synthetic, competitive inhibitor of HMG-CoA reductase, exhibiting an IC50 value of 8 nM. It safeguards vascular smooth muscle cells from oxidative stress by activating the Nrf2-dependent antioxidant pathway.
T10403	Atorvastatin ethyl ester	Others	Others
	Atorvastatin ethyl ester, a derivative of Atorvastatin, exhibits potent inhibition of 9-cis-RA-induced Gal4 reporter activity.
T7072	Pitavastatin
	Pitavastatin (NK-104) 是有效的羟甲基戊二酰-CoA(HMG-CoA)还原酶抑制剂。Pitavastatin 抑制乙酸合成胆固醇，在 HepG2 细胞中的IC50为 5.8 nM。Pitavastatin 是一种高效的肝细胞低密度脂蛋白胆固醇 (LDL-C) 受体诱导剂。Pitavastatin 具有抗动脉粥样硬化、抗哮喘、抗骨关节炎、抗肿瘤、神经保护、肝保护和肾保护等作用。
T13380	(Z)-Pitavastatin calcium	Others	Others
	(Z)-Pitavastatin calcium is the Z-Isomer of Pitavastatin hemicacium. Pitavastatin calcium is a potent of hydroxymethylglutaryl-CoA (HMG-CoA) reductase.
T72155	(Rac)-3′-Hydroxy simvastatin
	(Rac)-3′-Hydroxy simvastatin 是一种 Simvastatin 代谢物。Simvastatin 是一种竞争性的 HMG-CoA 还原酶抑制剂，Ki 值为 0.2 nM。
T10131	(3S,5R)-Rosuvastatin	Others	Others
	(3S,5R)-Rosuvastatin is the (3R,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor (IC50: 11 nM).

化合物

2-Hydroxy atorvastatin calcium salt

Cat.No: TQ0045

Target: Drug Metabolite

(Rac)-5-Keto Fluvastatin

Cat.No: T12652

Synonym: 5-Ketofluvastatin,3-Hydroxy-5-Keto Fluvastatin,rac 5-Keto Fluvastatin

Target: Others

Fluvastatin sodium

Cat.No: T1487

Synonym: XU 62320 sodium,XU-62-320,氟伐他汀钠,Fluvastatin sodium salt

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T21405

Synonym: Canef,XU-62320,Vastin,Cranoc,Lescol

Target: HMG-CoA Reductase

Pitavastatin lactone

Cat.No: T12490

Target: Others

Atorvastatin Sodium

Cat.No: T20887

Synonym: Lipitor

Target: LDL, Aquaporin, HMG-CoA Reductase

Anhydrosimvastatin

Cat.No: T10324

Synonym: Dehydro simvastatin,脱水辛伐他汀

Target: HMG-CoA Reductase

Atorvastatin lactone

Cat.No: T14342

Target: HMG-CoA Reductase

Cat.No: T24865

Synonym: L-654969,L654969,Simvastatin acid,L 654969,Simvastatin hydroxy acid

Target: ROS, HMG-CoA Reductase

Cat.No: T25285

Synonym: RG-12561,RG 12561,RG12561

Target: HMG-CoA Reductase

Tert-Buthyl Pitavastatin

Cat.No: T13131

Target: HMG-CoA Reductase

Pitavastatin calcium

Cat.No: T2534

Synonym: P-872441,nisvastatin,itavastatin,Pitavastatin hemicalcium,匹伐他汀钙,NK-104

Target: Apoptosis, Mitophagy, Endogenous Metabolite, HMG-CoA Reductase, Autophagy

Rosuvastatin calcium

Cat.No: T1510

Synonym: ZD 4522 Calcium,ZD4522,Rosuvastatin hemicalcium,瑞舒伐他汀钙

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Cat.No: T25276

Synonym: PMD387,PMD 387,PMD-387

Target: HMG-CoA Reductase

Cat.No: T1676

Synonym: 罗伐他汀,ZD 4522,瑞舒伐他汀

Target: Potassium Channel, HMG-CoA Reductase, Autophagy

Atorvastatin hemicalcium salt

Cat.No: T3116

Synonym: Lipitor,Atorvastatin hemicalcium,Atorvastatin Calcium,CI-981,阿托伐他汀钙,Sortis

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Lovastatin hydroxy acid sodium

Cat.No: T19918

Synonym: 6-α-Methylcompactin sodium,Lovastatin Na,Lovastatin Sodium,Mevinolin sodium

Atorvastatin hemicalcium trihydrate

Cat.No: T72101

Synonym: 阿托伐他汀半钙三水合物,阿托他伐汀半钙三水合物

3α-Hydroxy pravastatin sodium

Cat.No: T40913

Atorvastatin Epoxy Tetrahydrofuran Impurity

Cat.No: T10402

Target: Others

O-Methyl Atorvastatin hemicalcium

Cat.No: T12283

Target: Others

Atorvastatin acetonide tert-butyl ester

Cat.No: T10400

Target: Others

3-Oxo Atorvastatin

Cat.No: T10120

Target: Others

Atorvastatin strontium

Cat.No: T71492

Atorvastatin acetonide

Cat.No: T10401

Target: Others

Acetyllovastatin

Cat.No: T10235

Target: Others

(3R,5R)-Rosuvastatin

Cat.No: T10126

Target: Others

2-Hydroxy atorvastatin lactone

Cat.No: T38249

Desfluoro-atorvastatin

Cat.No: T15099

Target: Others

Rosuvastatin zinc salt

Cat.No: T81257

Synonym: Rosuvastatin zinc

Rosuvastatin D6 Calcium

Cat.No: T19551

Target: Others

Fluvastatin D6 sodium

Cat.No: T11306

Synonym: XU 62-320 (D6)

Target: Others

(3S,5R)-Fluvastatin sodium

Cat.No: T10129

Synonym: (3S,5R)-XU 62-320

Target: Others

(3S,5S)-Pitavastatin calcium

Cat.No: T10132

Target: Others

Rosuvastatin lactone

Cat.No: T69178

Rosuvastatin Sodium

Cat.No: T63430

Atrovastatin-PEG3-FITC

Cat.No: T38920

Synonym: Atrovastatin-PEG3-FITC

Cat.No: T71705

Difluoro atorvastatin

Cat.No: T15127

Synonym: Fluoroatorvastatin

Target: Others

Fluvastatin-d6 Sodium Salt

Cat.No: TMIH-0242

Pitavastatin D4

Cat.No: T12488

Synonym: NK-104 D4

Target: Others

(3R,5S)-Atorvastatin sodium

Cat.No: T10127

Target: Others

Atorvastatin magnesium trihydrate

Cat.No: T71560

(3S,5S)-Atorvastatin

Cat.No: T21080

Synonym: ent-Atorvastatin,3S,5S-Atorvastatin,(3S,5S)-阿托伐他汀

(3R,5S)-Fluvastatin

Cat.No: T39036

Synonym: (3R,5S)-Fluvastatin,(3R,5S)-XU 62-320 free acid

Atorvastatin ethyl ester

Cat.No: T10403

Target: Others

Cat.No: T7072

(Z)-Pitavastatin calcium

Cat.No: T13380

Target: Others

(Rac)-3′-Hydroxy simvastatin

Cat.No: T72155

(3S,5R)-Rosuvastatin

Cat.No: T10131

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0683	Mevastatin Compactin,ML236B,美伐他汀	Apoptosis; Antibacterial; Antibiotic; HMG-CoA Reductase; Autophagy; Lipid	Apoptosis; Autophagy; Metabolism; Microbiology/Virology
	Mevastatin (ML236B) 是他汀类 HMG-CoA 还原酶抑制剂。它是一种降脂药，可诱导细胞凋亡，将癌细胞阻滞在 G0/G1期。它还可增加内皮型一氧化氮合酶的 mRNA 和蛋白质水平。它有抗肿瘤活性，用于心血管疾病的研究。
T0672	Pravastatin sodium CS-514 Sodium,普伐他汀钠,CS-514 (sodium)	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Pravastatin sodium (CS-514 (sodium)) 是一种 HMG-CoA 还原酶抑制剂，抑制甾醇合成，IC50 为 5.6 μM。
T1207	Lovastatin MK-803,洛伐他汀,Mevinolin	Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Lovastatin (MK-803) 是一种 HMG-CoA 还原酶抑制剂，用于降低胆固醇。
T0687	Simvastatin 辛伐他汀,MK-0733,MK 733	Apoptosis; Mitophagy; Ferroptosis; HMG-CoA Reductase; Autophagy	Apoptosis; Autophagy; Metabolism
	Simvastatin (MK 733) 是一种 HMG-CoA 还原酶抑制剂 (Ki=0.2 nM)，具有口服活性。Simvastatin 具有降血脂活性，可以抑制肝脏产生胆固醇，还可以用于预防心血管疾病。
T16885	Simvastatin acid ammonium 辛伐他汀铵盐,Tenivastatin ammonium	Others	Others
	Simvastatin ammonium is an active metabolite of simvastatin lactone mediated. Simvastatin ammonium reduces indoxyl sulfate-mediated reactive oxygen species and modulates OATP3A1 expression in cardiomyocytes and HEK293 cells transfected with the OATP3A1 ge

天然产物

Cat.No: T0683

Synonym: Compactin,ML236B,美伐他汀

Target: Apoptosis, Antibacterial, Antibiotic, HMG-CoA Reductase, Autophagy, Lipid

Pravastatin sodium

Cat.No: T0672

Synonym: CS-514 Sodium,普伐他汀钠,CS-514 (sodium)

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T1207

Synonym: MK-803,洛伐他汀,Mevinolin

Target: Ferroptosis, HMG-CoA Reductase, Autophagy

Cat.No: T0687

Synonym: 辛伐他汀,MK-0733,MK 733

Target: Apoptosis, Mitophagy, Ferroptosis, HMG-CoA Reductase, Autophagy

Simvastatin acid ammonium

Cat.No: T16885

Synonym: 辛伐他汀铵盐,Tenivastatin ammonium

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-00921	COL8A1 Protein, Human, Recombinant (His) Vastatin,Endothelial Collagen,Collagen Alpha-1(VIII...	Human	HEK293 Cells
	Collagen alpha-1(VIII) chain, also known as endothelial collagen, C3orf7 and COL8A1, can be cleaved into vastatin chain. COL8A1 is a short chain collagen and a major component of the basement membrane of the corneal endothelium. COL8A1 forms homotrimers, or heterotrimers in association with alpha 2(VIII) type collagens. Four homotrimers can form a tetrhedron stabilized by central interacting C-terminal NC1 trimers. COL8A1 contains one C1q domain and is primarily expressed in the subendothelium o...

重组蛋白

COL8A1 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00921

Species: Human

Expression System: HEK293 Cells

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