87
25
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T9016 |
AI-10-47
1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47 |
Others | Others |
AI-10-47 (1H-Benzimidazole, 2-(2-pyridinyl)-6-(trifluoromethoxy)-AI-10-47) 是 CBFβ-RUNX 结合的小分子抑制剂(IC50:3.2 μM)。 | |||
T15789 |
LTURM34
|
DNA-PK; PI3K; PI4K | DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling |
LTURM34 是一种 DNA-PK 抑制剂,IC50 为 34 nM。它在广泛的肿瘤细胞系中显示出有效的抗增殖活性,对 DNA-PK 的选择性比 PI3K 高 170 倍。 | |||
T8594 |
Pheneturide
2-PHENYLBUTYRYLUREA,S-46,Benuride,苯丁酰脲 |
Others | Others |
Pheneturide (Benuride) 是Phenobarbita l 脱羧后的产物,可阻止精神运动性癫痫发作。 | |||
T3658 |
Trifluridine/tipiracil hydrochloride mixture
Trifluridine-tipiracil hydrochloride mixture,TAS102,TAS-102,TAS 102 |
Nucleoside Antimetabolite/Analog; DNA/RNA Synthesis | Cell Cycle/Checkpoint; DNA Damage/DNA Repair |
Trifluridine/tipiracil hydrochloride mixture (TAS-102) 是一种新型口服组合药物,含有摩尔比为 2:1 的曲氟尿苷(TFT) 和盐酸替吡嘧啶 (TTP)。它主要通过抑制胸苷酸合酶 (TS) 和掺入 DNA 来显示抗肿瘤活性。 | |||
T6053 |
Turofexorate Isopropyl
XL335,FXR-450,WAY-362450,妥芬异丙酯 |
FXR; Autophagy | Autophagy; Metabolism |
Turofexorate Isopropyl (XL335) 是一种口服有效的,选择性 FXR 激动剂,EC50为 4 nM。 | |||
T1145 |
Diminazene Aceturate
|
Others; Serine Protease; Parasite | Microbiology/Virology; Others; Proteases/Proteasome |
Diminazene aceturate 是血管紧张素转化酶 2 的激活剂,具有强效抗炎特性。它还是一种抗锥虫药物,适用于牲畜。它主要生化机理是通过与富含腺嘌呤-胸腺嘧啶碱基对的位点发生特异性相互作用,以非插入方式与锥虫动子体 DNA 结合。 | |||
T10760 |
Ceramides Mixture
神经酰胺混合物,神经酰胺 |
Telomerase | DNA Damage/DNA Repair |
Ceramides Mixture 是表皮渗透屏障的主要脂质成分,参与生长抑制,细胞周期停滞和端粒酶活性的调节。它是一种内源性神经酰胺,由含羟基和非羟基脂肪酸的神经酰胺组成。 | |||
T1819 |
Nexturastat A
|
HDAC | Chromatin/Epigenetic; DNA Damage/DNA Repair |
Nexturastat A 是一种有效且特异性的 HDAC6 抑制剂,IC50: 5 nM。它的选择性是其他 HDAC 的 190 倍以上。 | |||
T71703L |
Isomer-Turosteride
Isomer-Turosteride(Isomer-137099-09-3) |
Reductase | Endocrinology/Hormones; Metabolism |
Isomer-Turosteride (Isomer-Turosteride(Isomer-137099-09-3)) 是一种新型 5α- 还原酶抑制剂。Isomer-Turosteride 在成年大鼠中的抗前列腺作用与抑制T向 DHT 的转化有关。Isomer-Turosteride引起前列腺 DHT 的降低,与 T 含量的继发性增加无关。Isomer-Turosteride 具有抗癌活性,可抑制肿瘤细胞的生长。 | |||
T19761 |
Sulfometuron-methyl
DXP 5648,DXP-5648,甲嘧磺隆,DXP5648 |
Antibacterial | Microbiology/Virology |
Sulfometuron-methyl (DXP-5648) 是一种除草剂,也是一种活性抗菌剂。它是乙酰乳酸合酶 II 的有效抑制剂,因此具有抗菌特性。 | |||
T66282 | 5-Norbornene-2-methylamine (mixture of isomers) | ||
5-Norbornene-2-methylamine (mixture of isomers) 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66282,CAS号为 95-10-3。 | |||
T28031 |
Meturedepa
AB-132,AB132,AB 132 |
||
Meturedepa is an antineoplastic agent. | |||
T13946 |
Turbinaric acid
|
Others | Others |
Turbinaric acid, a secosqualene carboxylic acid with cytotoxic properties, originates from the brown alga Turbinaria ornata. | |||
T75345 |
HKSOX-1m (5/6-mixture) (hydrobromide)
|
||
HKSOX-1m (5/6-mixture) hydrobromide 是靶向线粒体的 O2•−荧光探针(Ex/Em=509/534 nm; 绿色),具有极好的选择性,且在较大范围的 pH 值区间,细胞中即使有大量强氧化剂和还原剂的时候依然有效。 | |||
T38933 |
HKYellow-AM (6/12-mixture)
|
||
HKYellow-AM (6/12-mixture) is a fluorogenic probe, which can be used for sensitive and specific detection of peroxynitrite. | |||
T38082 |
Tunicamycin 15:1 Mixture
|
||
Tunicamycin 15:1 is a mixture of tunicamycin structural isomers that contain a 15-carbon N-acyl chain with variable branching patterns. The N-acyl chain incorporated into tunicamycins, like tunicamycin 15:1, is derived from the same pool of cellular branched-chain fatty acids (BCFAs) inStreptomycesand directly impacts the biological activity of each individual tunicamycin variant.1,2,3Purified tunicamycin 15:1 withiso,anteiso, or a mixture ofisoandanteisobranching configurations inhibit bacteria... | |||
T35983 |
Carotenoid Mixture
|
||
Carotenoid mixture is a mixture of carotenoids that contains the antioxidative and anti-inflammatory carotenoid capsanthin and the antioxidative vitamin A precursor β-carotene , as well as additional carotenoids and carotenoid esters.1,2,3,4 1.Kim, J.S., Lee, W.M., Rhee, H.C., et al.Red paprika (Capsicum annuum L.) and its main carotenoids, capsanthin and β-carotene, prevent hydrogen peroxide-induced inhibition of gap-junction intercellular communicationChem. Biol. Interact.254146-155(2016) 2.Na... | |||
T11216 |
Eplivanserin (mixture)
Eplivanserin mixture,SR-46349 (mixture) |
5-HT Receptor | GPCR/G Protein; Neuroscience |
Eplivanserin mixture is a selective serotonin reuptake inhibitor and a 5-HT2A receptor antagonist, | |||
T125635 |
Nocturnoside B
|
||
Nocturnoside B 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T125635,CAS号为 166604-02-0。 | |||
T35553 |
Ganglioside GQ1b Mixture (sodium salt)
|
||
Ganglioside GQ1b is a tetrasialoganglioside that contains two sialic acid residues linked to an inner galactose unit. It stimulates phosphorylation of several ecto-type protein kinase substrates on the surface of GOTO human neuroblastoma cells when used at a concentration of 5 nM. Ganglioside GQ1b promotes differentiation of murine embryonic stem cells (mESCs) to neuronal precursor and glial cells via activation of the ERK1/2 pathway. It also induces differentiation of murine keratinocytes throu... | |||
T35587 |
Ganglioside GD1a mixture (sodium salt)
Ganglioside B1 |
||
Ganglioside GD1a is a sialic acid-containing glycosphingolipid found in brain, erythrocytes, bone marrow, testis, spleen, and liver. [1] It can be shed from the surface of tumor cells into the microenvironment where it influences tumor-host cell interactions to promote tumor cell proliferation, invasion, and metastasis. Ganglioside GD1a (20 μM) also increases endothelial cell proliferation. Furthermore, ganglioside GD1a has been shown to act as a functional coreceptor for toll-like receptor 2 (T... | |||
TMIH-0426 |
Permethrin-d5 (cis/trans mixture)
|
||
Permethrin-d5 (cis/trans mixture) 是 Permethrin (cis/trans mixture) 的氘代化合物。 | |||
TMIH-0483 |
Ractopamine-d6 (Mixture of Diastereomers)
|
||
Ractopamine-d6 (Mixture of Diastereomers) 是 Ractopamine (Mixture of Diastereomers) 的氘代化合物。 | |||
T24994 |
MreB Perturbing Compound A22 hydrochloride
A22 hydrochloride,MreB Perturbing Compound A22 |
||
A22 is an inhibitor of MreB, an actin-like bacterial protein, and has been proved to be an antibiotic adjuvant. A22 inhibition of MreB disrupts the bacterial actin cytoskeleton, which can cause an increase in cell permeability and altered transport. | |||
T124118 | Iturin A8 | ||
Iturin A8 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124118,CAS号为 83856-07-9。 | |||
T73936 |
HKSOX-1 (5/6-mixture)
|
||
HKSOX-1 是一种荧光探针,用于成像和检测活细胞以及体内的内源性超氧化物。 HKSOX-1 对超氧阴离子自由基具有极好的选择性和敏感性。储存方式:避光。 | |||
TP2280 |
ovalbumin (324-338) [Gallus gallus]/[Coturnix coturnix]
|
Others | Others |
Ovalbumin is the main protein found in egg white, making up 60-65% of the total protein. Ovalbumin is an important protein in several different areas of research, including general studies of protein structure and properties. Ovalbumin is used for studies | |||
T36469 |
Atrazine Mercapturate
|
||
Atrazine mercapturate is a major, glutathione-derived metabolite of atrazine , an herbicide that is effective in controlling a broad range of weeds. Atrazine has been reported to cause cancer in certain laboratory animals, have diverse effects on the reproductive system in animals and humans, and disrupt the normal function of the endocrine system. Atrazine mercapturate is readily measured in urine samples. | |||
T124119 |
Iturin A2
|
||
Iturin A2 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124119,CAS号为 83785-07-3。 | |||
T37582 |
Ganglioside GM1 Mixture (ovine) (ammonium salt)
|
||
Ganglioside GM1is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue.1,2It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane.3It associates with growth factor receptors, including TrkA, TrkB, and the GDNF receptor complex containing Ret and GFRα, and is required for TrkA expression on the cell surface. Ganglioside GM1interacts with other proteins to increase calcium i... | |||
T124120 |
Iturin A4
|
||
Iturin A4 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T124120,CAS号为 83777-00-8。 | |||
T33032 |
Lynestrenol mixture with mestranol
|
||
Lynestrenol mixture with mestranol is a bioactive chemical. | |||
T30788 |
Cefoperasone mixture with sulbactam
Bacamp,Sulperazone,Cefactam,Jincetam |
||
Cefoperasone mixture with sulbactam is a bioactive chemical. | |||
T35552 |
Ganglioside GD3 Mixture (sodium salt)
|
||
Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases. It induces apoptosis in HuT-78 cutaneous T cell lymphoma cells in a concentration-dependent manner and disrupts the mitochondrial membrane potential when used at a concentration of 200 μM. Expression of ganglioside GD3 in GD3-negative SK-MEL-28-N1 malignant melanoma cells increa... | |||
T36862 |
Ganglioside GT1b Mixture (sodium salt)
Ganglioside GT1b Mixture (sodium salt),Ganglioside G1 Mixture |
||
Ganglioside GT1b is a trisialoganglioside that is characterized by having two sialic residues linked to the inner galactose unit. It binds to the neurotoxins botulinum toxin serotype A (BTxA), BTxA heavy chain, and tetanus toxin with IC50 values of 11, 0.74, and 7.2 μM, respectively.[1] Ganglioside GT1b-containing liposomes bind to the major coat protein VP1 from Merkel cell polyomavirus (MCPyV), which has been identified in Merkel cell carcinomas, identifying ganglioside GT1b as a putative MCP... | |||
T35930 |
Ganglioside GM2 Mixture (sodium salt)
|
||
Ganglioside GM2 is a glycosphingolipid component of cellular membranes, primarily the plasma membrane. Levels of ganglioside GM2 are elevated in the brain of patients with Sandhoff disease, as well as feline and mouse models of the disease. Ganglioside GM2 accumulates in the lysosomes of individuals with Tay-Sachs disease and GM2-activator deficiency, as well as in the CNS of patients with and animal models of mucopolysaccharide storage disorders and Niemann-Pick disease types A, C1, and C2. Gan... | |||
T31699 |
Ethinylestradiol mixture with Levonorgestrel
|
||
Ethinylestradiol mixture with Levonorgestrel is formulated with increasing dosages of levonorgestrel and ethinyl estradiol. | |||
T64298 |
Turoctocog alfa
|
||
Turoctocog alfa 是一种来源于中国仓鼠卵巢 (CHO) 细胞的重组凝血因子 VIII (FVIII)。Turoctocog alfa 能够用于研究 A 型血友病。 | |||
T64286 |
Quinidine polygalacturonate
|
||
Quinidine polygalacturonate 是一种有效的、选择性的、口服具有活力的细胞色素 P450db (cytochrome P450db) 抑制剂,也是一种有效的 K+通道 (K+channel) 阻断剂,其 IC50值为 19.9 μM,也能够诱导凋亡。Quinidine polygalacturonate 是一种抗心律失常剂,也能够用于研究疟疾。 | |||
T73956 | Amoxicillin trihydrate mixture with potassium clavulanate (4:1) | ||
Amoxicillin (trihydrate) mixture with potassium clavulanate (4:1) 是一种抗生素 (antibiotic),具有优良的口服吸收性及广谱抗菌作用。该化合物通过抑制细胞壁内多肽的生物合成来阻止细胞生长。 | |||
T74929 | Phytoene desaturase-IN-1 | ||
Phytoene desaturase-IN-1 是高效的PDS抑制剂(Kd: 65.9 μM),通过与Phe301残基形成π-π堆叠效应。该化合物显示出广谱的芽后除草活性,并能在白化病叶片中诱导PDS mRNA水平下降及八氢番茄红素与ROS累积,适用于农业生产。 | |||
T35588 |
Ganglioside GM3 Mixture (sodium salt)
|
||
Ganglioside GM3 is a monosialoganglioside that demonstrates antiproliferative and proapoptotic effects in tumor cells by modulating cell adhesion, proliferation, and differentiation. It suppresses angiogenesis and reduces proliferation and migration of human umbilical vein endothelial cells (HUVECs) when used at a concentration of 20 μM via inhibition of VEGFR2 and Akt phosphorylation. Ganglioside GM3 induces dissociation of the insulin receptor-caveolin-1 complex from lipid microdomains, functi... | |||
T31715 |
Ethynylestradiol mixture with lynestrenol
|
||
Ethynylestradiol mixture with lynestrenol is a drug/ therapeutic agent with reproductive effect. | |||
T66188 |
5-Norbornen-2-ol, mixture of endo and exo
|
||
5-Norbornen-2-ol, mixture of endo and exo 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66188,CAS号为 13080-90-5。 | |||
T126160 |
Apigenin 7-[rhamnosyl-(1->2)-galacturonide]
|
||
Apigenin 7-[rhamnosyl-(1->2)-galacturonide] 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126160。 | |||
T38027 |
Ganglioside GM2 Asialo Mixture
Ganglioside GM2 Asialo Mixture |
||
Ganglioside GM2 asialo (asialo- GM2) is a glycosphingolipid containing three monosaccharide residues and a fatty acid of variable chain length but lacking the sialic acid residue present on ganglioside M2. Asialo-GM2 levels are low-to-undetectable in normal human brain, but it accumulates in the brain of patients with Tay-Sachs and Sandhoff disease, which are neurodegenerative disorders characterized by deficiency of lysosomal β-hexosaminidase A and B, respectively. It also binds to various bact... | |||
T126060 |
Turmeronol B
|
||
Turmeronol B 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T126060。 | |||
T27858 |
LTURM-36
LTURM 36,LTURM36 |
||
LTURM-36 is a novel inhibitor of PI 3-kinase delta. | |||
T29628 |
Acyclovir mixture with hydrocortisone
Xerese,ME 609,ME609,ME-609,Lipsovir |
||
Acyclovir mixture with hydrocortisone is used for Herpes simplex labialis. | |||
T32226 |
Isoproturon-diflufenican mixt.
FR-1288,FR1288,Blutron plus,Blutron,FR 1288 |
||
Isoproturon-diflufenican mixt. is a herbicide. |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T80346 |
Tur1A
|
||
Tur1A,宽吻海豚源抗菌肽,通过结合核糖体并阻断蛋白质合成从起始阶段至延伸阶段的转变,抑制细菌蛋白质合成。 | |||
T3S1457 |
Palmaturbine
Palmatrubin,巴马亭红碱,Palmatrubine |
Others | Others |
Palmaturbine (Palmatrubine) 从T. sinensis 中分离,有高抗肿瘤活性。 | |||
T5680 |
Aloin(mixture of A&B)
芦荟素,葡糖基蒽酮,芦荟大黄素甙,芦荟苷 |
MMP; IL Receptor; Antibacterial; Antifungal | Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome |
Aloin (mixture of A&B) 是一种从芦荟中分离出来的蒽醌衍生物。它是刺激性粒细胞基质金属蛋白酶的有效抑制剂。它具有多种生物活性,如抗炎、抗菌、抗真菌、抗氧化、抗肿瘤、抗糖尿病和免疫活性。 | |||
T20550 |
Thiobarbituric acid
NSC4733,NSC 4733,4,6-二羟基-2-巯基嘧啶,NSC-4733 |
Antibacterial | Microbiology/Virology |
Thiobarbituric acid (NSC-4733) 具有抗菌活性。 | |||
T5583 |
Turanose
松二糖,D-(+)-Turanose |
Endogenous Metabolite | Metabolism |
Turanose (D-(+)-Turanose) 是天然存在于蜂蜜中的蔗糖异构体。它具有抗炎和调节脂肪形成的活性。它具有肥胖症和相关慢性病的研究潜力。 | |||
T4786 |
D-Ribose(mixture of isomers)
D-Ribose,D-(-)-Ribose,D-(-)-核糖 |
Others; Endogenous Metabolite | Metabolism; Others |
D-Ribose(mixture of isomers) (D-(-)-Ribose) 是 ATP 的糖部分,可作为能量增强剂,被广泛用作慢性疲劳综合症和心肌能量代谢的代谢疗法补充剂。它在蛋白质糖化中具有特性,能够 RAGE 依赖的方式诱导 NF-Κb 炎症。 | |||
TJO2795 |
D-Galacturonic acid hydrate
D-(+)-Galacturonic acid,D-半乳糖醛酸 |
Others; Endogenous Metabolite | Metabolism; Others |
D-Galacturonic acid hydrate 是内源性代谢产物的一种。 | |||
TN5196 |
Turmeronol A
|
Others | Others |
Turmeronol A and turmeronol B are inhibitors of soybean lipoxygenase, they inhibited soybean lipoxygenase at the IC50 values of 16 uM and 9 uM, respectively. | |||
T73954 | Leucinostatin (mixture of A&B) | ||
Leucinostatin (mixture of A&B) 是来自Paecilomyces lilacinus 的九肽类复合物,具有抗生素活性。 | |||
TN3775 |
Daturataturin A aglycone
|
Others | Others |
Daturataturin A aglycone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3775,CAS号为 904665-71-0。 | |||
TN2287 |
Turkesterone
|
Calcium Channel | Membrane transporter/Ion channel; Metabolism |
Turkesterone is a phytoecdysteroid possessing an 11alpha-hydroxyl group, also is an analogue of the insect steroid hormone 20-hydroxyecdysone. It has immunomodulating and antistress activity, can increase the adaptation capacity of mice under immobilization-induced stress conditions. | |||
T78488 |
Palmaturbine hydroxide
|
||
Palmaturbine hydroxide是从T. sinensis中分离出的化合物。 | |||
TN3774 |
Daturametelin I
|
Others | Others |
Daturametelin I 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3774,CAS号为 904667-65-8。 | |||
T78490 |
Polygalacturonic acid
Galacturonic acid polymer |
||
Polygalacturonic acid(Galacturonic acid polymer)为透明胶状物,构成细胞壁关键组分。该酸应用于制备银纳米颗粒(AgNPs),充当抗氧化剂与抗炎剂,防护细胞遭受ROS增高引起的损伤,并促进伤口愈合。Polygalacturonic acid纳米颗粒亦显示抗菌性能。 | |||
T40600 |
Iturin A
|
||
Iturin A is a chemical compound with potent antifungal properties against pathogenic yeast and fungi. It interacts with the cytoplasmic membrane of the target cell, leading to the formation of ion conducting pores. | |||
TN5371 |
8-Hydroxy-ar-turmerone
|
||
8-Hydroxy-ar-turmerone may exhibit antitumor activity against breast cancer cells via cell death and cell cycle arrest. | |||
TN3773 |
Daturabietatriene
|
Others | Others |
Daturabietatriene is a natural product from Pinus yunnanensis. | |||
T23505 |
Venturicidin A
|
Others | Others |
Venturicidin A is a macrolide antibiotic. | |||
T82300 |
Gluconasturtiin
|
||
Gluconasturtiin 作为P. maculipennis幼虫的摄食诱导剂,但其高浓度会对幼虫产生毒害效应。 | |||
TN3776 |
Daturataturin A
|
Others | Others |
Daturataturin A是一种天然产物,属于茄科曼陀罗属,其产品编号为 TN3776,CAS号为 133360-51-7。Daturataturin A可用作对照参考。 | |||
TN2932 |
3-Epiturraeanthin
|
Others | Others |
3-Epiturraeanthin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN2932,CAS号为 22415-24-3。 | |||
TN6570 |
Daturaolone
|
||
Daturaolone has potency in reducing the harmful effects or in maintaining the normal hepatic physiological mechanisms in both acute and chronic hepato-toxic induced liver damage in rats. Daturaolone also possesses in vivo anti-inflammatory and antinocicep | |||
T36044 |
17-hydroxy Venturicidin A
|
||
17-hydroxy Venturicidin A is a macrolide fungal metabolite originally isolated from Streptomyces. It has antibiotic activity against M. luteus, B. subtilis, and S. aureus and antifungal activity against V. dahlia, Fusarium, and C. tropicalis in a disc assay. | |||
TN6845 |
D-Galacturonic acid monohydrate
|
||
D-Galacturonic acid monohydrate is a natural product. | |||
T14317 |
ar-Turmerone
(+)-ar-Turmerone |
Others | Others |
ar-Turmerone ((+)-ar-Turmerone) is a major bioactive compound of the herb Curcuma longa with anti-tumorigenesis and anti-inflammatory activities[1][2][3]. ar-Turmerone ((+)-ar-Turmerone) exerts positive modulation on murine DCs, induces NSC proliferation. |