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信号通路 血管生成 凋亡 自噬 细胞周期 表观遗传 细胞骨架
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代谢 微生物学 神经科学 NF-κB信号通路 氧化还原 PI3K/Akt/mTOR信号通路 蛋白酶体
干细胞 蛋白酪氨酸激酶 泛素化 PROTAC 其他
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Fragment片段库 高溶解性片段库 精选片段库 高溶解性多官能团片段化合物库 高溶解性卤化片段化合物库 药物片段库 Mini片段亲电杂环化合物库 高溶解性微型片段化合物库
类药性化合物库 多样性核心库Part2 多样性核心库Part1 药物靶点库 多样性核心预制库 Golden骨架库 Mini骨架库 化合物库深度定制
TargetMol Compound Library
天然产物库 高通量筛选天然产物库 特色天然产物库 天然产物衍生物库 虚拟筛选天然产物库
结构类型 萜类 类固醇 类黄酮 醌类 香豆素 木脂素 多糖和糖苷
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植物来源 列当科 水龙骨科 南洋杉科 报春花科 海金沙科 商陆科 买麻藤科
萝藦科 肉豆蔻科 鸭跖草科 交让木科 三白草科 海桐花科 五味子科 红厚壳科
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基于靶点筛选实体化合物活性筛选 分子结合&互作检测 酶学靶点活性检测 核受体靶点活性检测 GPCR靶点活性检测
基于表型筛选实体化合物活性筛选 细胞增殖检测 细胞周期检测 细胞凋亡检测 药代动力学研究
药物设计和结构优化 化合物定制合成 分子砌块 网络药理学平台 软件平台
细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白
CAR-T 细胞治疗靶点蛋白 •   血液恶性肿瘤靶点蛋白 •   实体瘤靶点蛋白 酶 •   氧化还原酶 •   转移酶
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搜索结果

Search Results for " t9 "
Targets Recommended: Parasite PI4K

9

抑制剂 & 化合物

1

天然产物

21

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T13246 UCT943

Parasite; PI4K Microbiology/Virology; PI3K/Akt/mTOR signaling
UCT943是恶性疟原虫PI4K 的抑制剂（IC50 = 23 nM）。
T3068 AT9283

J-504568

 Apoptosis; FLT; JAK; Bcr-Abl; Aurora Kinase; Autophagy Angiogenesis; Apoptosis; Autophagy; Cell Cycle/Checkpoint; Chromatin/Epigenetic; Cytoskeletal Signaling; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
AT9283 (J-504568) 是一种多靶点激酶抑制剂，抑制多种实体瘤在体内外的生长和存活，有效抑制Aurora A/B，JAK2/3，Abl (T315I)，和Flt3，IC50值范围为 1-30 nM。
T14841 BVT948

Phosphatase; P450; Histone Methyltransferase Chromatin/Epigenetic; Metabolism
BVT948 是一种蛋白酪氨酸磷酸酶抑制剂，还可以抑制赖氨酸甲基转移酶 SETD8 (KMT5A) 和几种细胞色素 P450 (P450) 同工型。
T5207 LIT927

LIT 927,LIT-927

 CXCR Autophagy; GPCR/G Protein; Immunology/Inflammation
LIT927 (LIT-927) 是一种具有口服活性的 CXCL12 中性配体（对于 CXCL12 与 CXCR4 的结合，Ki：267 nM）。
T4354 KPT9274

KPT-9274,KPT 9274,PAK4-IN-1

 NAMPT; PAK Cytoskeletal Signaling; Metabolism
KPT9274 (PAK4-IN-1) 是一种非竞争性的 PAK4 和 NAMPT 双重抑制剂（IC50= ~120 nM）。它是一种口服生物可利用的小分子。
T7302 CU-CPT9b

CU-CPT-9b,TLR8-specific antagonist 1

 TLR Immunology/Inflammation
CU-CPT9b (TLR8-specific antagonist 1) 是 toll 样受体 8 (TLR8) 的拮抗剂，Kd 为 21 nM。它抑制由 TLR8 激动剂 R-848 在过表达 TLR8 的 HEK-Blue 细胞中诱导的 NF-ĸB 活化，IC5​​0 值为 0.7 nM。
T76593 (Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)

'(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)' 为一种GnRH类似物，主要用于诱导养殖鱼类排卵和/或产卵。
T69227 GT951

GT951 is a EAAT2 activator.
T33616 NDT9520492

NDT 9520492,NDT-9520492
NDT9520492 is a bioactive chemical.

化合物

UCT943
Cat.No: T13246
Synonym:
Target: Parasite, PI4K
AT9283
Cat.No: T3068
Synonym: J-504568
Target: Apoptosis, FLT, JAK, Bcr-Abl, Aurora Kinase, Autophagy
BVT948
Cat.No: T14841
Synonym:
Target: Phosphatase, P450, Histone Methyltransferase
LIT927
Cat.No: T5207
Synonym: LIT 927,LIT-927
Target: CXCR
KPT9274
Cat.No: T4354
Synonym: KPT-9274,KPT 9274,PAK4-IN-1
Target: NAMPT, PAK
CU-CPT9b
Cat.No: T7302
Synonym: CU-CPT-9b,TLR8-specific antagonist 1
Target: TLR
(Des-Gly10,D-Ala6,Pro-NHEt9)-LHRH (salmon)
Cat.No: T76593
Synonym:
Target:
GT951
Cat.No: T69227
Synonym:
Target:
NDT9520492
Cat.No: T33616
Synonym: NDT 9520492,NDT-9520492
Target:
Cat. No. Product Name Target Signaling Pathways
T81052 T988C

(+)-T988C
T988C为一种七环ETP（epidithiodioxopiperazine）天然产物，对P388白血病细胞系培养细胞显示出显著的细胞毒性。

天然产物

T988C
Cat.No: T81052
Synonym: (+)-T988C
Target:
Species：
Human (10)
SARS-CoV-2 (10)
Cynomolgus (1)
Expression System：
HEK293 (17)
Baculovirus-Insect Cells (3)
Human Cells (1)
Tag：
His (12)
His,AVI (2)
N-His-Avi (2)
hFc (2)
C-hFc (1)
N-6His (1)
N-His (1)
Cat. No. Product Name Species Expression System
TMPY-05096 Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc)

CD71,T9,transferrin receptor,TFR1,p90,TRFR,TFR,TR

 Human HEK293
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system...
TMPY-01873 Transferrin Receptor/TFRC Protein, Human, Recombinant (His)

TFR1,p90,CD71,TFR,transferrin receptor,T9,TRFR,TR

 Human HEK293
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system...
TMPY-01897 PRSS3 Protein, Human, Recombinant (His)

PRSS4,TRY4,TRY3,RP11-176F3.3,T9,MTG,protease, serin...

 Human HEK293
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ...
TMPK-01261 Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His)

TFR,T9,CD71,TfR1,sTfR,TFRC,TR,p90

 Cynomolgus HEK293
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
TMPK-00376 Transferrin R/CD71 Protein, Human, Recombinant (hFc)

sTfR,CD71,TfR1,TFR,p90,TFRC,TR,T9

 Human HEK293
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
TMPJ-00378 Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)

p90,TfR,T9,Trfr,Transferrin receptor protein 1,TR

 Human Human Cells
Transferrin receptor protein 1 (TFRC) belongs to the peptidase M28 family that is synthesized as a 172 amino acid (aa). TFRC regulated by cellular iron levels through binding of the iron regulatory proteins, IRP1 and IRP2, to iron-responsive elements in the 3'-UTR. It binds one transferrin or HFE molecule per subunit and binds the HLA class II histocompatibility antigen, DR1. It Interacts with SH3BP3 and STEAP3, facilitates TFRC endocytosis in erythroid precursor cells. Cellular uptake of iron o...
TMPK-00375 Transferrin R/CD71 Protein, Human, Recombinant (His & Avi), Biotinylated

TFRC,sTfR,T9,p90,CD71,TR,TFR,TfR1

 Human HEK293
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
TMPK-00374 Transferrin R/CD71 Protein, Human, Recombinant (His & Avi)

p90,TFR,sTfR,T9,TFRC,TfR1,CD71,TR

 Human HEK293
The transferrin receptor (CD71) is known as a receptor for IgA1 on mesangial cells. The transcript and protein expression of glomerular CD71 was determined by real-time polymerase chain reaction and immunohistochemistry. Human mesangial cells (HMCs) were treated with sera from IgAN patients and expression levels of CD71 and inflammatory cytokine markers were compared according to disease status.
TMPY-05617 Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated

TRFR,p90,TR,TFR,CD71,TFR1,T9,transferrin receptor

 Human HEK293
Transferrin receptor protein 1, also known as transferrin receptor, Trfr, p9, CD71 and TFRC, is a single-pass type II membrane protein that belongs to the peptidase M28 family and M28B subfamily. TFRC / CD71 is a membrane-bound protein expressed in larger amounts in proliferating. The specific expression of TFRC can represent a diagnostic tool or a therapeutic target in solid tumours expressing this antigen. Transferrin receptor is necessary for development of erythrocytes and the nervous system...
TMPY-02845 CST9L Protein, Human, Recombinant (hFc)

bA218C14.1,CTES7B,UNQ1835,PRO3543,cystatin 9-like

 Human HEK293
Testatin is a member of the Cystatin family. Cystatins comprise genes that all show expression patterns that are strikingly restricted to reproductive tissue. Cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. There are typically about 115 amino acids in this family. They are largely acidic, contain four conserved cysteine residues known to form two disulfide bonds, may be glycosylated and/or phosphorylated, with similarity to fetuins, kininogens, stefins, ...
TMPY-06647 CHST9 Protein, Human, Recombinant (His)

GalNAc4ST2,carbohydrate (N-acetylgalactosamine 4-0) sulfotra...

 Human HEK293
CHST9 Protein, Human, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 17.66 kDa. Accession number: NP_113610.2
TMPY-06393 SARS-CoV-2 Spike S1+S2 Protein (L5F & T95I & D253G & S477N & E484K & D614G & A701V, His)

SARS-CoV-2 Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06251 SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His)

SARS-CoV-2 HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06443 SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06422 SARS-CoV-2 Spike S1 NTD Protein (T19R & T95I & G142D & 156-157 deletion & R158G, His)

SARS-CoV-2 HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06395 SARS-CoV-2 Spike S1 Protein (L5F & T95I & D253G & S477N & E484K & D614G, His)

SARS-CoV-2 HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06271 SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His)

SARS-CoV-2 Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06421 SARS-CoV-2 Spike S1 Protein (T95I & Y144S & Y145N & R346K & E484K & N501Y & D614G & P681H, His)

SARS-CoV-2 HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06287 SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His & Avi), Biotinylated

SARS-CoV-2 Baculovirus-Insect Cells
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06444 SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)

SARS-CoV-2 HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...
TMPY-06293 SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His & Avi), Biotinylated

SARS-CoV-2 HEK293
The spike (S) glycoprotein of coronaviruses contains protrusions that will only bind to certain receptors on the host cell. Known receptors bind S1 are ACE2, angiotensin-converting enzyme 2; DPP4, dipeptidyl peptidase-4; APN, aminopeptidase N; CEACAM, carcinoembryonic antigen-related cell adhesion molecule 1; Sia, sialic acid; O-ac Sia, O-acetylated sialic acid. The spike is essential for both host specificity and viral infectivity. The term 'peplomer' is typically used to refer to a grouping of...

重组蛋白

Transferrin Receptor/TFRC Protein, Human, Recombinant (hFc)
Cat.No: TMPY-05096
Species: Human
Expression System: HEK293
Transferrin Receptor/TFRC Protein, Human, Recombinant (His)
Cat.No: TMPY-01873
Species: Human
Expression System: HEK293
PRSS3 Protein, Human, Recombinant (His)
Cat.No: TMPY-01897
Species: Human
Expression System: HEK293
Transferrin R/CD71 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPK-01261
Species: Cynomolgus
Expression System: HEK293
Transferrin R/CD71 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00376
Species: Human
Expression System: HEK293
Transferrin Receptor/TFRC Protein, Human, Recombinant (aa 101-760, His)
Cat.No: TMPJ-00378
Species: Human
Expression System: Human Cells
Transferrin R/CD71 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00375
Species: Human
Expression System: HEK293
Transferrin R/CD71 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00374
Species: Human
Expression System: HEK293
Transferrin Receptor/TFRC Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-05617
Species: Human
Expression System: HEK293
CST9L Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02845
Species: Human
Expression System: HEK293
CHST9 Protein, Human, Recombinant (His)
Cat.No: TMPY-06647
Species: Human
Expression System: HEK293
SARS-CoV-2 Spike S1+S2 Protein (L5F & T95I & D253G & S477N & E484K & D614G & A701V, His)
Cat.No: TMPY-06393
Species: SARS-CoV-2
Expression System: Baculovirus-Insect Cells
SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His)
Cat.No: TMPY-06251
Species: SARS-CoV-2
Expression System: HEK293
SARS-CoV-2 Spike S1 Protein (T19R & T95I & G142D & Y145H & E156G & 157-158 deletion & A222V & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06443
Species: SARS-CoV-2
Expression System: HEK293
SARS-CoV-2 Spike S1 NTD Protein (T19R & T95I & G142D & 156-157 deletion & R158G, His)
Cat.No: TMPY-06422
Species: SARS-CoV-2
Expression System: HEK293
SARS-CoV-2 Spike S1 Protein (L5F & T95I & D253G & S477N & E484K & D614G, His)
Cat.No: TMPY-06395
Species: SARS-CoV-2
Expression System: HEK293
SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His)
Cat.No: TMPY-06271
Species: SARS-CoV-2
Expression System: Baculovirus-Insect Cells
SARS-CoV-2 Spike S1 Protein (T95I & Y144S & Y145N & R346K & E484K & N501Y & D614G & P681H, His)
Cat.No: TMPY-06421
Species: SARS-CoV-2
Expression System: HEK293
SARS-CoV-2 Spike S1+S2 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R & Q1071H, His & Avi), Biotinylated
Cat.No: TMPY-06287
Species: SARS-CoV-2
Expression System: Baculovirus-Insect Cells
SARS-CoV-2 Spike S1 Protein (T19R & T95I & E156G & 157-158 deletion & L452R & T478K & D614G & P681R, His)
Cat.No: TMPY-06444
Species: SARS-CoV-2
Expression System: HEK293
SARS-CoV-2 Spike S1 Protein (T95I & G142D & E154K & L452R & E484Q & D614G & P681R, His & Avi), Biotinylated
Cat.No: TMPY-06293
Species: SARS-CoV-2
Expression System: HEK293
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