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Search Results for " rotenone "

9

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T13432	β-Apo-13-carotenone D3 D'Orenone D3	Others	Others
	β-Apo-13-carotenone D3 is the deuterium labeled β-Apo-13-carotenone. β-Apo-13-carotenone is an antagonist of RXRα.
T130419	6-Hydroxyrotenone
	6-Hydroxyrotenone 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T130419。
T25300	Dehydrorotenone
	Dehydrorotenone is a retinoid of Tephrosia egregia and has great antioxidant activity.
T13431	β-Apo-13-carotenone D'Orenone	Others	Others
	β-Apo-13-carotenone is a naturally occurring β-apocarotenoid, and is a RXRα antagonist.
T4446	Tebufenpyrad Pyranica,吡螨胺,MK239,Comanche	Mitochondrial Metabolism	Metabolism
	Tebufenpyrad (Comanche) 是一种重要的农业化学杀螨剂，其作用类似于已知的线粒体毒物 rotenone。
T0727	Piperonyl butoxide Pyrenone 606,ENT-14250,Ethanol butoxide,Butacide,增效醚	Others; Parasite	Microbiology/Virology; Others
	Piperonyl butoxide (Pyrenone 606) 是黄樟素的半合成衍生物, 用作农药制剂的一个组成部分, 它是杀虫剂增效剂。
T29792	AK-135
	AK-135 is a derivative of 1,4-naphthoquinone (Menadione). AK-135 has been shown to restore the electron flow in defective respiratory chain (hypoxia or rotenone) systems more effectively than Menadione.
T68547	SNJ-1945
	SNJ-1945 is a calpain inhibitor with more favorable retinal penetration, high oral bioavailability, and long half-life. SNJ1945 rescued defective function in lissencephaly. SNJ-1945 protects SH-SY5Y cells against MPP(+) and rotenone. SNJ-1945 reduces murine retinal cell death in vitro and in vivo. SNJ-1945 has good aqueous solubility, can prevents the heart from KCl arrest-reperfusion injury associated with the impairment of total Ca(2+) handling by inhibiting the proteolysis of alpha-fodrin a...
T79333	LZWL02003	Reactive Oxygen Species	Immunology/Inflammation; Metabolism; NF-κB
	LZWL02003为抗神经炎症化合物，对MPP+引起的神经元损害展示保护效果，有效降低ROS水平。此外，LZWL02003能改善鱼藤酮诱导的帕金森病(PD)大鼠模型在认知、记忆、学习及运动能力方面的缺陷。该化合物在神经退行性疾病的研究中具有应用潜力。

化合物

β-Apo-13-carotenone D3

Cat.No: T13432

Synonym: D'Orenone D3

Target: Others

6-Hydroxyrotenone

Cat.No: T130419

Dehydrorotenone

Cat.No: T25300

β-Apo-13-carotenone

Cat.No: T13431

Synonym: D'Orenone

Target: Others

Cat.No: T4446

Synonym: Pyranica,吡螨胺,MK239,Comanche

Target: Mitochondrial Metabolism

Piperonyl butoxide

Cat.No: T0727

Synonym: Pyrenone 606,ENT-14250,Ethanol butoxide,Butacide,增效醚

Target: Others, Parasite

Cat.No: T29792

Cat.No: T68547

Cat.No: T79333

Target: Reactive Oxygen Species

Cat. No.	Product Name	Target	Signaling Pathways
T2970	Rotenone Rotenon,鱼藤酮,Paraderil,Barbasco,Rotocide,Dactinol	Apoptosis; Dehydrogenase; Mitochondrial Metabolism; p53; Autophagy	Apoptosis; Autophagy; Metabolism
	Rotenone (Rotocide) 属于天然产物，是一种植物杀虫剂。Rotenone 是一种线粒体电子传递复合物 I 抑制剂，可以促进线粒体产生活性氧，并诱导细胞凋亡。
T11685	Isolongifolene 异长叶烯,(-)-Isolongifolene	Apoptosis; Others	Apoptosis; Others
	Isolongifolene ((-)-Isolongifolene) 是一种从调料九里香中分离的三环倍半萜烯，具有抗氧化，抗炎，抗癌和神经保护的特性。它通过调节 PI3K/AKT/GSK-3β 信号通路来减轻鱼藤酮诱导的氧化应激，线粒体功能障碍和细胞凋亡。
TN1586	Dihydrorotenone	Apoptosis; Mitochondrial Metabolism	Apoptosis; Metabolism
	Dihydrorotenone 是一种线粒体抑制剂，是天然杀虫剂。它通过触发内质网应激并激活 p38 信号通路来诱导人浆细胞凋亡，可能诱发帕金森综合症。
T34394	Rotenolone 12ALPHA-羟基鱼藤酮,Rotenolone I,12alpha-HYDROXYROTENONE	Others	Others
	Rotenolone (12alpha-HYDROXYROTENONE) 是鱼藤酮的代谢物，鱼藤酮是一种源自藤本植物和龙果属植物的天然化合物。
T81524	Peimisine 3-O-β-D-glucopyranoside
	Peimisine 3-O-β-D-glucopyranoside (compound 1) 是一种从单苞贝母鳞茎中分离得到的甾体生物碱。该化合物对鱼藤酮诱导的PC12细胞系神经毒性展现出中等程度的保护效果。
TN4635	Neoechinulin A	NADPH-oxidase; Beta Amyloid; ASK; IκB/IKK; p38 MAPK; TNF; NOS; NF-κB; COX; Prostaglandin Receptor	Apoptosis; GPCR/G Protein; Immunology/Inflammation; MAPK; Neuroscience; NF-κB
	Neoechinulin A has anti-inflammatory effect against LPS-stimulated RAW264.7 macrophages through inhibition of the NF-ÎºB and p38 MAPK pathways, it may block the phosphorylation of mitogen-activated protein kinase (MAPK) molecule p38, apoptosis signal-regu

天然产物

Cat.No: T2970

Synonym: Rotenon,鱼藤酮,Paraderil,Barbasco,Rotocide,Dactinol

Target: Apoptosis, Dehydrogenase, Mitochondrial Metabolism, p53, Autophagy

Cat.No: T11685

Synonym: 异长叶烯,(-)-Isolongifolene

Target: Apoptosis, Others

Dihydrorotenone

Cat.No: TN1586

Target: Apoptosis, Mitochondrial Metabolism

Cat.No: T34394

Synonym: 12ALPHA-羟基鱼藤酮,Rotenolone I,12alpha-HYDROXYROTENONE

Target: Others

Peimisine 3-O-β-D-glucopyranoside

Cat.No: T81524

Cat.No: TN4635

Target: NADPH-oxidase, Beta Amyloid, ASK, IκB/IKK, p38 MAPK, TNF, NOS, NF-κB, COX, Prostaglandin Receptor

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