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Search Results for " l tyrosine "

29

抑制剂 & 化合物

15

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T19922	L-m-Tyrosine L(-)mTyrosine,3-羟基-L-苯基丙氨酸,L (-) m Tyrosine,LmTyrosine,3-Hydroxy-L-Phenylalanine,L-(-)-m-Tyrosine	Others	Others
	L-m-Tyrosine (3-Hydroxy-L-Phenylalanine) 是一种非天然氨基酸。L-m-Tyrosine 在治疗帕金森病、关节炎和阿尔茨海默病方面显示出潜力。
T40846	3,5-Difluoro-L-tyrosine
	3,5-Difluoro-L-tyrosine is a functional and tyrosinase-resistant mimic of tyrosine, commonly utilized for evaluating the substrate specificity of protein tyrosine phosphatases (PTPs).
T40408	N-Pivaloyl-L-tyrosine
	N-Pivaloyl-L-tyrosine is an N-pivaloyl amino acid ester.
T36384	DL-Tyrosine-13C9,15N L-Tyrosine-13C9,15N
	L-Tyrosine-13C9,15N is intended for use as an internal standard for the quantification of L-tyrosine by GC- or LC-MS. L-Tyrosine is a non-essential amino acid.1It is produced by hydroxylation of phenylalanine by phenylalanine hydroxylase but can also be obtained from dietary sources or degradation of endogenous proteins, resulting in L-tyrosine release.1,2L-Tyrosine is a precursor in the biosynthesis of catecholamine neurotransmitters, melanins, and thyroid hormones.3Plasma, skeletal muscle, and...
T20698	Leucyltyrosine L-Leucyl-L-tyrosine
	Leucyltyrosine is a dipeptide.
T67308	3-Fluoro-L-tyrosine
	3-Fluoro-L-tyrosine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67308。
T126438	L-Tyrosine, methyl ester
	L-Tyrosine, methyl ester 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126438，CAS号为 1080-06-4。
T31162	Cysteinyltyrosine N-L-Cysteinyl-L-tyrosine,Cys-tyr
	Cysteinyltyrosine is a dipeptide composed of cysteine and tyrosine. It is an incomplete breakdown product of protein digestion or protein catabolism.
T20554	N-Benzoyltyrosine N-Benzoyl-L-tyrosine
	N-benzoyl tyrosine is a dipeptide.
T65730	N-Fmoc-3-nitro-L-tyrosine
	N-Fmoc-3-nitro-L-tyrosine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65730，CAS号为 136590-09-5。
T32675	Leucyl-leucyl-tyrosine L-Leu-L-leu-L-tyr
	Leucyl-leucyl-tyrosine is a bioactive chemical.
T124433	3-Nitro-L-tyrosine ethyl ester hydrochloride
	3-Nitro-L-tyrosine ethyl ester hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124433。
T65630	N-Benzoyl-L-tyrosine ethyl ester
	N-Benzoyl-L-tyrosine ethyl ester 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65630，CAS号为 3483-82-7。
T77237	N,O-Didansyl-L-tyrosine cyclohexylammonium
	N,O-Didansyl-L-tyrosine cyclohexylammonium 是一种有效的选择性胸苷酸合成酶 (TS) 抑制剂，作用于Escherichia coli，Lactobacillus casei 和人的 TS 的IC50值分别是 5.0，3.4 和 119 μM。
T40840	H-Tyr-Ala-OH H-Tyr-Ala-OH,Tyrosylalanine	Others	Others
	H-Tyr-Ala-OH (Tyrosylalanine) 是一种L-酪氨酸和L-丙氨酸组成的二肽。
T5467	SAR125844 SAR125884	Apoptosis; c-Met/HGFR	Apoptosis; Tyrosine Kinase/Adaptors
	SAR125844 是高度选择性可逆ATP 竞争性的MET 受体酪氨酸激酶抑制剂，其IC50值为4.2 nM。能抑制细胞中MET 的自磷酸化。
T41274	p-Fluoro-L-phenylalanine	Hydroxylase	Metabolism
	p-Fluoro-L-phenylalanine 是酪氨酸羟化酶的一种底物。它可以与大肠杆菌的 L-亮氨酸特异性受体结合，KD 为0.26 μM。
T11727	JPH203 dihydrochloride KYT-0353 dihydrochloride	Others	Others
	JPH203 dihydrochloride (KYT-0353 dihydrochloride) 是一种酪氨酸类似物，可作为 L 型氨基酸转运蛋白 1 (LAT1) 的选择性抑制剂，用于癌症研究。
T5473	ASP5878 ASP-5878	FGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	ASP5878 是一种 FGFR 1 (IC50:0.47 nM)、FGFR 2 (IC50:0.6 nM)、FGFR 3 (IC50:0.74 nM)、和 FGFR 4 (IC50:3.5 nM)的抑制剂，具有口服活性，具有潜在的抗肿瘤作用。
T3691	(Rac)-SAR131675 SAR131675	VEGFR	Angiogenesis; Tyrosine Kinase/Adaptors
	(Rac)-SAR131675 是一种有效的、选择性的VEGFR3抑制剂，其IC50=23 nM。
T2500	Cediranib AZD2171,NSC-732208,西地尼布	VEGFR; FLT; PDGFR; c-Kit; Autophagy	Angiogenesis; Autophagy; Tyrosine Kinase/Adaptors
	Cediranib (AZD2171) 是一种可口服的高选择性VEGFR2抑制剂，对Flt1、KDR、Flt4、PDGFRα、PDGFRβ和c-Kit 的IC50值分别为小于1、小于3、5、5、36和 2nM。
T27513	GW7845 GW 7845,GW-7845
	GW7845, an L-tyrosine derivative, is a PPAR-γ agonist.
T31410	D-Fluoromethyltyrosine F-18 BAY 86 9596,BAY 869596,BAY 86-9596,J2.566.882K,BAY-86-9596 F-18
	Fluoroethyl-l-tyrosine (18F) or 18F-FET is a neuro-oncology PET tracer.
T24039	Erbstatin
	Erbstatin is a tyrosine-protein kinase inhibitor. When combined with foroxymithine, it has antineoplastic activity against L-1210 leukemia.
T41208	NB-caged Tyrosine hydrochloride ONBY,NB-caged Tyrosine hydrochloride
	NB-caged Tyrosine hydrochloride is a L-Tyrosine caged with photosensitiveortho-nitrobenzyl side chain. Rapidly releases tyrosine when photolyzed (300-350 nm excitation). Is readily incorporated intoE.coliproteins via inclusion in growth media.
T19890	Tyrosyl-glycyl-glycine
	Tyrosyl-glycyl-glycine 是一种由脑啡肽酶释放的三肽，是一种代谢产物，由一个L-酪氨酸和两个甘氨酸残基按顺序连接而成。
T74045	H-Lys-Tyr-OH TFA
	H-Lys-Tyr-OH TFA (Lysyltyrosine TFA)为L-赖氨酸与L-酪氨酸构成的二肽。该化合物通过促进去甲肾上腺素与酪氨酸在大脑中的释放，用于预防神经系统疾病或提升大脑功能。
T71576	SIM010603
	SIM010603 is a structurally novel, oral, multi-targeted receptor tyrosine kinase inhibitor. SIM010603 inhibited stem cell factor receptor (Kit), vascular endothelial growth factor receptor-2 (VEGFR-2), platelet-derived growth factor receptor-β (PDGFR-β), glial cell line-derived neurotrophic factor receptor (Rearranged during Transfection; RET), and Fms-like tyrosine kinase-3 (FLT3) with IC(50) values between 5.0 and 68.1 nmol/l. SIM010603 inhibited the phosphorylation of PDGFR-β and VEGFR-2. Mor...
T71082	DW532
	DW532 is one of simplified analogues of hematoxylin that has shown broad-spectrum inhibition on tyrosine kinases and in vitro anti-cancer activities. DW532 inhibited EGFR and VEGFR2 in vitro kinase activity (the IC50 values were 4.9 and 5.5 μmol/L, respectively), and suppressed their downstream signaling. DW532 dose-dependently inhibited tubulin polymerization via direct binding to tubulin, thus disrupting the mitotic spindle assembly and leading to abnormal cell division. In a panel of human ca...

化合物

Cat.No: T19922

Synonym: L(-)mTyrosine,3-羟基-L-苯基丙氨酸,L (-) m Tyrosine,LmTyrosine,3-Hydroxy-L-Phenylalanine,L-(-)-m-Tyrosine

Target: Others

3,5-Difluoro-L-tyrosine

Cat.No: T40846

N-Pivaloyl-L-tyrosine

Cat.No: T40408

DL-Tyrosine-13C9,15N

Cat.No: T36384

Synonym: L-Tyrosine-13C9,15N

Cat.No: T20698

Synonym: L-Leucyl-L-tyrosine

3-Fluoro-L-tyrosine

Cat.No: T67308

L-Tyrosine, methyl ester

Cat.No: T126438

Cysteinyltyrosine

Cat.No: T31162

Synonym: N-L-Cysteinyl-L-tyrosine,Cys-tyr

N-Benzoyltyrosine

Cat.No: T20554

Synonym: N-Benzoyl-L-tyrosine

N-Fmoc-3-nitro-L-tyrosine

Cat.No: T65730

Leucyl-leucyl-tyrosine

Cat.No: T32675

Synonym: L-Leu-L-leu-L-tyr

3-Nitro-L-tyrosine ethyl ester hydrochloride

Cat.No: T124433

N-Benzoyl-L-tyrosine ethyl ester

Cat.No: T65630

N,O-Didansyl-L-tyrosine cyclohexylammonium

Cat.No: T77237

Cat.No: T40840

Synonym: H-Tyr-Ala-OH,Tyrosylalanine

Target: Others

Cat.No: T5467

Synonym: SAR125884

Target: Apoptosis, c-Met/HGFR

p-Fluoro-L-phenylalanine

Cat.No: T41274

Target: Hydroxylase

JPH203 dihydrochloride

Cat.No: T11727

Synonym: KYT-0353 dihydrochloride

Target: Others

Cat.No: T5473

Synonym: ASP-5878

Target: FGFR

(Rac)-SAR131675

Cat.No: T3691

Synonym: SAR131675

Target: VEGFR

Cat.No: T2500

Synonym: AZD2171,NSC-732208,西地尼布

Target: VEGFR, FLT, PDGFR, c-Kit, Autophagy

Cat.No: T27513

Synonym: GW 7845,GW-7845

D-Fluoromethyltyrosine F-18

Cat.No: T31410

Synonym: BAY 86 9596,BAY 869596,BAY 86-9596,J2.566.882K,BAY-86-9596 F-18

Cat.No: T24039

NB-caged Tyrosine hydrochloride

Cat.No: T41208

Synonym: ONBY,NB-caged Tyrosine hydrochloride

Tyrosyl-glycyl-glycine

Cat.No: T19890

H-Lys-Tyr-OH TFA

Cat.No: T74045

Cat.No: T71576

Cat.No: T71082

Cat. No.	Product Name	Target	Signaling Pathways
T0493	L-Tyrosine Tyrosine,P-Tyrosine,L-酪氨酸,L-p-Tyrosine,(S)-Tyrosine,酪氨酸	Amino Acids and Derivatives; Endogenous Metabolite	Metabolism
	L-Tyrosine ((S)-Tyrosine) 是一种非必需氨基酸，对后部皮层中柠檬酸合成酶具有抑制活性。
TN6749	3,5-Diiodo-L-tyrosine dihydrate	Others	Others
	3,5-Diiodo-L-tyrosine dihydrate 是一种天然产物。
T4890	3-Nitro-L-tyrosine 3-Nitrotyrosine,3-硝基-L-酪氨酸	Endogenous Metabolite	Metabolism
	3-Nitro-L-tyrosine (3-Nitrotyrosine) 在系统自免疫原性条件下，能够作无氮自由基修饰蛋白的生物标记物。
T5280	3-Chloro-L-Tyrosine 3-氯-L-酪氨酸,3-Chlorotyrosine,Chlorotyrosine	Others; Endogenous Metabolite	Metabolism; Others
	3-Chloro-L-Tyrosine (Chlorotyrosine) 是一种髓过氧化物酶催化氧化的特异性标志物，在从人动脉粥样硬化内膜分离的低密度脂蛋白中显著升高。
T5292	N-Acetyl-L-tyrosine N-乙酰-L-酪氨酸,N-Acetyltyrosine,Ac-Tyr-OH	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-L-tyrosine (Ac-Tyr-OH) 是一种来源于AA 乙酰酶作用下的酪氨酸，和芳香族氨基酸脱羧酶缺乏症以及酪氨酸血症有关，能够作为儿茶酚胺的前体，用于治疗神经递质。
T5568	H-Tyr(3-I)-OH 3-碘-L-酪氨酸,3-Iodo-L-tyrosine	Endogenous Metabolite	Metabolism
	H-Tyr(3-I)-OH (3-Iodo-L-tyrosine) 是酪氨酸羟化酶抑制剂和甲状腺激素的中间体。
T1653	Liothyronine Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine	Thyroid hormone receptor(THR); Endogenous Metabolite	Endocrinology/Hormones; Metabolism
	Liothyronine (Tresitope) 是一种有效的甲状腺激素，能够激活 β1 甲状腺激素受体 (TRβ1)。
T20555	Glycyltyrosine NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine
	Glycyltyrosine, a dipeptide composed of tyrosine and glycine, is an incomplete breakdown product of protein catabolism or protein digestion.
T3377	L-Phenylalanine L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine	Calcium Channel; Endogenous Metabolite; iGluR	Membrane transporter/Ion channel; Metabolism; Neuroscience
	L-Phenylalanine (3-Phenyl-L-alanine) 是分离自大肠杆菌的必需氨基酸，是 NMDARs(KB573 μM) 和非 NMDARs 的甘氨酸和谷氨酸结合位点的竞争性拮抗剂，用于食品香料和药品的生产中。它是一种电压依赖性 α2δ 亚基 Ca2+通道拮抗剂，Ki 为 980 nM。
T3737	3-(2,4-Dihydroxyphenyl)propanoic acid 3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid	Tyrosinase	Proteases/Proteasome
	3-(2,4-Dihydroxyphenyl)propanoic acid (Hydroumbellic acid) 是竞争性酪氨酸酶 (tyrosinase) 抑制剂，可抑制 L-Tyrosine 和 DL-DOPA，IC50和 Ki 分别为 3.02 μM 和 11.5 μM。
T4781	N-Acetyl-L-phenylalanine N-Ac-Phenylalanine,N-乙酰-L-苯丙氨酸	Others; Endogenous Metabolite	Metabolism; Others
	N-Acetyl-L-phenylalanine (N-Ac-Phenylalanine) 是一种大肠杆菌中的主要酰基氨基酸，由 L-苯丙氨酸和乙酰辅酶 A 合成。
T5290	(S)-2-Hydroxy-3-phenylpropanoic acid L-(−)-3-Phenyllactic acid,L-3-苯乳酸	Others; Endogenous Metabolite	Metabolism; Others
	(S)-2-Hydroxy-3-phenylpropanoic acid (L-(−)-3-Phenyllactic acid) 是苯丙氨酸的代谢产物。苯丙酮尿症患者体液中苯丙氨酸的水平升高。
T75563	Vanicoside E
	Vanicoside E 是一种抗氧化和抗癌剂。Vanicoside E 抑制L-Tyrosine 和L-DOPA，IC50为 45.23 μM 和 189.96 μM。
TN2288	Uralenol 乌拉尔醇	Others; Estrogen/progestogen Receptor; Tyrosinase	Endocrinology/Hormones; Others; Proteases/Proteasome
	Uralenol significantly shows the inhibitory activities against the PTP1B enzyme; it also shows inhibitory activities on mushroom tyrosinase using l-tyrosine as substrate( IC50 =49.5 μM). Uralenol shows potent anti-proliferation effects on ER-positive breast cancer MCF-7 cells in vitro.
TN3607	Catalpalactone	cAMP	GPCR/G Protein
	Catalpalactone exhibits high antitermitic, and cytotoxic activities, it exhibits potent inhibitory effects on lipopolysaccharide-induced NO synthesis in RAW 264.7 cells , with IC50 values of 9.80 microM. Catalpalactone can inhibit dopamine biosynthesis by

天然产物

Cat.No: T0493

Synonym: Tyrosine,P-Tyrosine,L-酪氨酸,L-p-Tyrosine,(S)-Tyrosine,酪氨酸

Target: Amino Acids and Derivatives, Endogenous Metabolite

3,5-Diiodo-L-tyrosine dihydrate

Cat.No: TN6749

Target: Others

3-Nitro-L-tyrosine

Cat.No: T4890

Synonym: 3-Nitrotyrosine,3-硝基-L-酪氨酸

Target: Endogenous Metabolite

3-Chloro-L-Tyrosine

Cat.No: T5280

Synonym: 3-氯-L-酪氨酸,3-Chlorotyrosine,Chlorotyrosine

Target: Others, Endogenous Metabolite

N-Acetyl-L-tyrosine

Cat.No: T5292

Synonym: N-乙酰-L-酪氨酸,N-Acetyltyrosine,Ac-Tyr-OH

Target: Others, Endogenous Metabolite

Cat.No: T5568

Synonym: 3-碘-L-酪氨酸,3-Iodo-L-tyrosine

Target: Endogenous Metabolite

Cat.No: T1653

Synonym: Tresitope,O-(4-Hydroxy-3-iodophenyl)-3,5-diiodo-L-tyrosine,碘噻罗宁,Triiodothyronine,三碘甲状腺原氨酸,L-3,3',5-Triiodothyronine,3,3',5-Triiodo-L-thyronine,Lyothyronine

Target: Thyroid hormone receptor(THR), Endogenous Metabolite

Cat.No: T20555

Synonym: NSC 118362,Gly Tyr,NSC-118362,Gly-Tyr,NSC118362,N-Glycyl-L-tyrosine

L-Phenylalanine

Cat.No: T3377

Synonym: L-苯丙氨酸,(S)-2-Amino-3-phenylpropionic acid,phenylalanine,3-Phenyl-L-alanine

Target: Calcium Channel, Endogenous Metabolite, iGluR

3-(2,4-Dihydroxyphenyl)propanoic acid

Cat.No: T3737

Synonym: 3-(2,4-二羟基苯)丙酸,Hydroumbellic acid,2,4-Dihydroxyhydrocinnamic acid

Target: Tyrosinase

N-Acetyl-L-phenylalanine

Cat.No: T4781

Synonym: N-Ac-Phenylalanine,N-乙酰-L-苯丙氨酸

Target: Others, Endogenous Metabolite

(S)-2-Hydroxy-3-phenylpropanoic acid

Cat.No: T5290

Synonym: L-(−)-3-Phenyllactic acid,L-3-苯乳酸

Target: Others, Endogenous Metabolite

Cat.No: T75563

Cat.No: TN2288

Synonym: 乌拉尔醇

Target: Others, Estrogen/progestogen Receptor, Tyrosinase

Cat.No: TN3607

Target: cAMP

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