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Search Results for " ifn-alpha "
Targets Recommended: Others IFNAR

7

抑制剂 & 化合物

1

天然产物

60

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T11630 IFN alpha-IFNAR-IN-1 hydrochloride

Others; IFNAR Immunology/Inflammation; Others
IFN alpha-IFNAR-IN-1 hydrochloride 是 IFN-α 和 IFNAR 相互作用的抑制剂。 IFN alpha-IFNAR-IN-1 hydrochloride 抑制 BM-pDCs 的 MVA 诱导的 IFN-α 反应,IC50 为 2-8 μM。
T11630L IFN alpha-IFNAR-IN-1

Others Others
IFN alpha-IFNAR-IN-1 is a nonpeptidic, low-molecular-weight inhibitor of the interaction between IFN-α and IFNAR. It inhibits MVA-induced IFN-α responses by BM-pDCs (IC50: 2-8 μM).
T12933 SM-276001

TLR; COX Immunology/Inflammation; Neuroscience
SM-276001 是可口服的干扰素诱导剂,是选择性TLR7激动剂,可以诱导抗肿瘤免疫反应。
T81259 Rontalizumab

RhuMab IFNalpha,Anti-Human IFN alpha Recombinant Antibody

Rontalizumab为针对IFN-α的人源化IgG1型单克隆抗体,适用于系统性红斑狼疮研究领域。
TP1117 IFN-α Receptor Recognition Peptide 1

IRRP1

IFN-α Receptor Recognition Peptide 1 is a peptide of IFN-α associated with receptor interactions.
T16169 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride

N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride

Others; Proteasome; COX Immunology/Inflammation; Neuroscience; Others; Proteases/Proteasome; Ubiquitination
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride (N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride) 是胰蛋白酶样蛋白酶的抑制剂。 N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride 对 IFN-γ 活性具有抑制作用。
T76853 Ropeginterferon alfa-2b

Ropeginterferon alfa-2b (Ropeginterferon alfa-2b-njft) 为单聚乙二醇化IFN-α类化合物,主要应用于骨髓增性肿瘤研究领域。

化合物

IFN alpha-IFNAR-IN-1 hydrochloride
Cat.No: T11630
Synonym:
Target: Others, IFNAR
IFN alpha-IFNAR-IN-1
Cat.No: T11630L
Synonym:
Target: Others
SM-276001
Cat.No: T12933
Synonym:
Target: TLR, COX
Rontalizumab
Cat.No: T81259
Synonym: RhuMab IFNalpha,Anti-Human IFN alpha Recombinant Antibody
Target:
IFN-α Receptor Recognition Peptide 1
Cat.No: TP1117
Synonym: IRRP1
Target:
N-alpha-Tosyl-L-lysine chloromethyl ketone hydrochloride
Cat.No: T16169
Synonym: N-alpha-Tosyl-L-lysine_chloromethyl_ketone_hydrochloride
Target: Others, Proteasome, COX
Ropeginterferon alfa-2b
Cat.No: T76853
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN4334 Isotaxiresinol

TNF Apoptosis
Isotaxiresinol prevents d-GalN/LPS-induced hepatic injury by inhibiting hepatocyte apoptosis through the blocking of TNF-alpha and IFN-gamma production by activated macrophages and direct inhibition of the apoptosis induced by TNF-alpha. Isotaxiresinol ma

天然产物

Isotaxiresinol
Cat.No: TN4334
Synonym:
Target: TNF
Cat. No. Product Name Species Expression System
TMPJ-00746 IFN-alpha 2b/IFNA2 Protein, Human, Recombinant

干扰素,IFNA2,Interferon α-2,Interferon α-A,Interferon ...

Human E. coli
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences by only one or two positions. Naturally occurring variants also include proteins that are truncated by 10 amino acids at the ca...
TMPJ-00745 IFN-alpha 2a/IFNA2 Protein, Human, Recombinant

Interferon α-2,IFNA2,干扰素,IFN α2a,IFN

Human E. coli
At least 23 different variants of IFN-α are known. The individual proteins have molecular masses between 19-26 kDa and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes only differ in their sequences by one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carboxy-ter...
TMPY-04578 Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)

Interferon α1,IFN-alphaD,IFN-αD,<...

Human P. pastoris (Yeast)
Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 20.8 kDa and the accession number is L0N195.
TMPY-00638 Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)

IFN-αB,IFN-alphaB,interferon, α8,...

Human HEK293 Cells
Interferon alpha B/IFNA8 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.9 kDa and the accession number is A0A7R8C381.
TMPY-04799 IFNAR2 Protein, Human, Recombinant (His), Biotinylated

IFN-R,interferon (α, β and Ω) receptor 2,IFN

Human HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-02515 Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)

IFN-alphaJ,干扰素,IFNA-J,IFN

Human HEK293 Cells
Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 48 kDa and the accession number is P01567.
TMPY-02647 IFNAR1 Protein, Human, Recombinant (His)

interferon (alpha, beta and omega) receptor 1,I...

Human HEK293 Cells
IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1.
TMPY-02566 Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His)

干扰素,interferon, α4,MGC142200,interferon, alpha 4,IN...

Human Baculovirus Insect Cells
Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 20.7 kDa and the accession number is P05014.
TMPY-00265 Interferon alpha 2/IFNA2 Protein, Human, Recombinant

IFNAB,干扰素,IFNA2B,IFN-alpha

Human P. pastoris (Yeast)
Interferon alpha 2/IFNA2 Protein, Human, Recombinant is expressed in yeast. The predicted molecular weight is 19.3 kDa and the accession number is P01563.1.
TMPK-00075 IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)

IFN-α-1/13,IFN α1,IFN alpha

Human HEK293 Cells
IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 46.14 kDa and the accession number is P01562.
TMPK-00074 IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)

IFN-α-1/13,IFN alpha1,干扰素,Interfe...

Mouse HEK293 Cells
IFN-α, a cytokine expressed in human islets from individuals affected by type 1 diabetes, plays a key role in the pathogenesis of diabetes by upregulating inflammation, endoplasmic reticulum (ER) stress and MHC class I overexpression, three hallmarks of islet histology in early type 1 diabetes. IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 45.88 kDa and the accession number is P01572.
TMPJ-00747 IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant

IFN-Alpha-2,Interferon α-A,IFN α2...

Mouse E. coli
At least 23 different variants of Interferon-α are known. The individual proteins have molecular masses between 19-26 kD and consist of proteins with lengths of 156-166 and 172 amino acids. All IFN-α subtypes possess a common conserved sequence region between amino acid positions 115-151 while the amino-terminal ends are variable. Many IFN-α subtypes differ in their sequences at only one or two positions. Naturally occurring variants also include proteins truncated by 10 amino acids at the carbo...
TMPJ-00780 IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)

Interferon α-K,Interferon α-6,IFN α6,Interferon α-5...

Human HEK293 Cells
Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN-α6 contains interferon alpha, beta and delta domain. IFN-α has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPY-02347 IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc)

interferon, alpha 13,RP23-139P14.1,IFN-α 1...

Mouse HEK293 Cells
IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.5 kDa and the accession number is Q80SU4.
TMPY-03891 IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His)

IFN-α 13,干扰素,interferon, alpha 13,interfer...

Mouse HEK293 Cells
IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.5 kDa and the accession number is Q80SU4.
TMPY-03320 IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc)

IFN-α 13,干扰素,interferon, alpha 13,IFN<...

Cynomolgus HEK293 Cells
IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.4 kDa and the accession number is G7NFW4.
TMPY-03375 IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His)

IFNA13,干扰素,interferon, α13,interferon, alpha

Cynomolgus HEK293 Cells
IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 20.8 kDa and the accession number is G7NFW4.
TMPK-00342 IFNAR1 Protein, Mouse, Recombinant (His & Avi)

IFN-α-REC,IFN-R-1,IFNAR1,IFN<...

Mouse HEK293 Cells
IFNAR1 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number is P33896.
TMPK-00325 IFNAR1 Protein, Human, Recombinant (His & Avi)

AVP,IFN-alpha-REC,IFN-α/β R1,...

Human HEK293 Cells
IFNAR1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPK-00343 IFNAR1 Protein, Mouse, Recombinant (hFc)

AVP,IFNBR,IFN-alpha/β R1,IFN<...

Mouse HEK293 Cells
IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.
TMPK-00326 IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated

IFN-alpha/β R1,IFN-α/β R1,IFN...

Human HEK293 Cells
IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPY-00830 interferon alpha 5/IFNA5 Protein, Human, Recombinant (hFc)

IFN-α,INFA5,interferon, alpha 5,IFN

Human HEK293 Cells
interferon alpha 5/IFNA5 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.3 kDa and the accession number is A0A7R8C382.
TMPY-04855 interferon alpha 5/IFNA5 Protein, Human, Recombinant (His)

leIF G,IFN-alpha,interferon-α,INA5,IFN...

Human P. pastoris (Yeast)
interferon alpha 5/IFNA5 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21.1 kDa and the accession number is A0A7R8C382.
TMPK-00637 IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)

β receptor10,IFNbR2,IFN α/β R2,IFN

Cynomolgus HEK293 Cells
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-...
TMPK-00889 IFNAR2 Protein, Human, Recombinant (aa 27-243, His)

IFN-alpha/beta R2,IFNAR2,IFN<...

Human HEK293 Cells
Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Human, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-His t...
TMPY-03648 Interferon alpha B/IFNA8 Protein, Human, Recombinant

IFN-αB,IFN-alphaB,interferon,

Human HEK293 Cells
Interferon alpha B/IFNA8 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 38 kDa and the accession number is A0A7R8C381.
TMPY-01640 IFNAR2 Protein, Human, Recombinant (hFc)

interferon (α, β and ω) receptor 2,IFNABR,IFN

Human HEK293 Cells
IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1.
TMPY-01642 IFNAR2 Protein, Human, Recombinant (His)

IFNARB,IFNABR,interferon (α, β and ω) rece...

Human HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-04841 Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His)

interferon, alpha 7,interferon, α7,IFN-αJ,...

Human P. pastoris (Yeast)
Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His) is expressed in yeast with His tag. The predicted molecular weight is 21 kDa and the accession number is A0A7R8C383.
TMPY-02516 Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)

interferon, α10,interferon, alpha 10,IFN-<...

Human HEK293 Cells
Interferon alpha-10 (IFNA10) is a member of the interferon family. Interferons belong to the group of the regulatory glycoproteins, of low molecular mass. They are the products of infected cell-genome, but not virus, as a consequence of the cause answer by different inductors. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. They allow communication between cells to trigger the protective defenses of the immune system that eradicate pathogen...
TMPJ-00331 IFNAR1 Protein, Rhesus macaque, Recombinant (His)

IFN-al,CRF2-1,IFN-alpha/beta rece...

Rhesus HEK293 Cells
Interferon‑alpha/beta receptor 1 (IFNalpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory...
TMPY-00829 Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc)

interferon, α4,IFN-α4a,干扰素,interferon, alpha

Human HEK293 Cells
Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46 kDa and the accession number is P05014.
TMPY-02634 IFNAR1 Protein, Human, Recombinant (hFc)

interferon (α, β and Ω) receptor 1,IFNBR,AVP,IF...

Human HEK293 Cells
IFNAR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74 kDa and the accession number is P17181-1.
TMPY-06407 Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc)

IFN-αA,INFA2,干扰素,Interferon α2,IFNA2B,inte...

Human HEK293 Cells
Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.29 kDa and the accession number is P01563-1.
TMPY-03758 Vaccinia Virus B18R/B19R Protein (His)

VACV Baculovirus Insect Cells
B18R is a type I interferon (IFN)-binding protein, which is encoded by the B18R open reading frame in the WR (Western Reserve) strain of vaccinia virus. It is also known as B19R in the Copenhagen strain of Vaccinia. B18R exists in a soluble and a membrane-bound form. As a type I IFN receptor, B18R has a broad species specificity. It has high affinity for human IFN-alpha and also binds rabbit, bovine, rat, pig, and mouse IFN-alpha and IFN-beta. It has been shown that secreted B18R binds to un...
TMPH-01547 Interferon alpha 21/IFNA21 Protein, Human, Recombinant (His)

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPH-01544 Interferon alpha 14/IFNA14 Protein, Human, Recombinant (His & SUMO)

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.
TMPH-01545 Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His)

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.4 kDa and the accession number is P05015.
TMPH-01546 Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His)

Human E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.3 kDa and the accession number is P01571.
TMPH-00276 Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO)

Bovine E. coli
Produced by macrophages, IFN-alpha have antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase. Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 35.2 kDa and the accession number is P49877.
TMPU-00003 STAT2 Protein, Human, Recombinant (His)

Human E. coli
Signal transducer and activator of transcription that mediates signaling by type I IFNs (IFN-alpha and IFN-beta). Following type I IFN binding to cell surface receptors, Jak kinases (TYK2 and JAK1) are activated, leading to tyrosine phosphorylation of STAT1 and STAT2. The phosphorylated STATs dimerize, associate with ISGF3G/IRF-9 to form a complex termed ISGF3 transcription factor, that enters the nucleus. ISGF3 binds to the IFN stimulated response element (ISRE) to activate the transcription of...
TMPH-02273 JAK1 Protein, Human, Recombinant (His)

Human P. pastoris (Yeast)
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors.
TMPH-02272 JAK1 Protein, Human, Recombinant (E. coli, His)

Human E. coli
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors.
TMPJ-00961 STAT1 Protein, Human, Recombinant

Transcription Factor ISGF-3 Components p91/p84,STAT1,Signal ...

Human E. coli
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellul...
TMPK-00317 IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated

IL-18 R α,IL-1 R5,IL18Ra,IL-18Ra,CD218a,IL-18 R alpha

Human HEK293 Cells
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPK-00512 IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)

IL18R1,IL-1 Rrp,CD218a,IL18Ra,IL-18Ra,IL-18 R alpha...

Cynomolgus HEK293 Cells
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPK-00316 IL-18R alpha Protein, Human, Recombinant (His & Avi)

CD218a,IL-18 R1,IL1RRP,IL-18Ra,IL-18 R alpha,IL-1 R...

Human HEK293 Cells
Interleukin-18 (IL-18) is a member of the interleukin-1 family of cytokines produced constitutively by different cell types and by adipose tissue. Interleukin (IL)-18 was originally discovered as a factor that enhanced IFN-γ production from anti-CD3-stimulated Th1 cells, especially in the presence of IL-12. Upon stimulation with Ag plus IL-12, naïve T cells develop into IL-18 receptor (IL-18R) expressing Th1 cells, which increase IFN-γ production in response to IL-18 stimulation. IL-18R alpha Pr...
TMPH-02961 JAK1 Protein, Mouse, Recombinant (His)

Mouse E. coli
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors. JAK1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.1 kDa and the accession numb...
TMPJ-00930 VCAM-1 Protein, Mouse, Recombinant (hFc)

Vascular cell adhesion protein 1,Vcam1

Mouse HEK293 Cells
Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages). IL-1 beta, IL-4, TNF-alpha and IFN-gamma induced the expression of VCAM-1. The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interac...
TMPJ-00344 IL-18RAP Protein, Human, Recombinant (hFc & His)

IL-1R accessory protein-like,Interleukin-18 receptor β,C,IL1...

Human HEK293 Cells
IL-18RAP is a single-pass type I membrane protein and contains two Ig-like C2-type domains and one TIR domain, IL18RAP can be induced by IFN-alpha and IL12 in nature killer cells and T-cells. The coexpression of IL18R1 and IL18RAP is required for the activation of NF-kappa B and JNK in response to IL-18.Defects in IL18RAP are associated with Coeliac disease.
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重组蛋白

IFN-alpha 2b/IFNA2 Protein, Human, Recombinant
Cat.No: TMPJ-00746
Species: Human
Expression System: E. coli
IFN-alpha 2a/IFNA2 Protein, Human, Recombinant
Cat.No: TMPJ-00745
Species: Human
Expression System: E. coli
Interferon alpha 1/IFNA1 Protein, Human, Recombinant (His)
Cat.No: TMPY-04578
Species: Human
Expression System: P. pastoris (Yeast)
Interferon alpha B/IFNA8 Protein, Human, Recombinant (His)
Cat.No: TMPY-00638
Species: Human
Expression System: HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-04799
Species: Human
Expression System: HEK293 Cells
Interferon alpha 7/IFNA7 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02515
Species: Human
Expression System: HEK293 Cells
IFNAR1 Protein, Human, Recombinant (His)
Cat.No: TMPY-02647
Species: Human
Expression System: HEK293 Cells
Interferon alpha 4/IFNA4 Protein, Human, Recombinant (His)
Cat.No: TMPY-02566
Species: Human
Expression System: Baculovirus Insect Cells
Interferon alpha 2/IFNA2 Protein, Human, Recombinant
Cat.No: TMPY-00265
Species: Human
Expression System: P. pastoris (Yeast)
IFN-alpha 1/IFNA1 Protein, Human, Recombinant (hFc)
Cat.No: TMPK-00075
Species: Human
Expression System: HEK293 Cells
IFN-alpha 1/IFNA1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00074
Species: Mouse
Expression System: HEK293 Cells
IFN-alpha 2/IFNA2 Protein, Mouse, Recombinant
Cat.No: TMPJ-00747
Species: Mouse
Expression System: E. coli
IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00780
Species: Human
Expression System: HEK293 Cells
IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPY-02347
Species: Mouse
Expression System: HEK293 Cells
IFN-alpha 13/IFNA13 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-03891
Species: Mouse
Expression System: HEK293 Cells
IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (hFc)
Cat.No: TMPY-03320
Species: Cynomolgus
Expression System: HEK293 Cells
IFN-alpha 13/IFNA13 Protein, Cynomolgus, Recombinant (His)
Cat.No: TMPY-03375
Species: Cynomolgus
Expression System: HEK293 Cells
IFNAR1 Protein, Mouse, Recombinant (His & Avi)
Cat.No: TMPK-00342
Species: Mouse
Expression System: HEK293 Cells
IFNAR1 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00325
Species: Human
Expression System: HEK293 Cells
IFNAR1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPK-00343
Species: Mouse
Expression System: HEK293 Cells
IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00326
Species: Human
Expression System: HEK293 Cells
interferon alpha 5/IFNA5 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00830
Species: Human
Expression System: HEK293 Cells
interferon alpha 5/IFNA5 Protein, Human, Recombinant (His)
Cat.No: TMPY-04855
Species: Human
Expression System: P. pastoris (Yeast)
IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)
Cat.No: TMPK-00637
Species: Cynomolgus
Expression System: HEK293 Cells
IFNAR2 Protein, Human, Recombinant (aa 27-243, His)
Cat.No: TMPK-00889
Species: Human
Expression System: HEK293 Cells
Interferon alpha B/IFNA8 Protein, Human, Recombinant
Cat.No: TMPY-03648
Species: Human
Expression System: HEK293 Cells
IFNAR2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-01640
Species: Human
Expression System: HEK293 Cells
IFNAR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01642
Species: Human
Expression System: HEK293 Cells
Interferon alpha 7/IFNA7 Protein, Human, Recombinant (His)
Cat.No: TMPY-04841
Species: Human
Expression System: P. pastoris (Yeast)
Interferon alpha 10/IFNA10 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02516
Species: Human
Expression System: HEK293 Cells
IFNAR1 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPJ-00331
Species: Rhesus
Expression System: HEK293 Cells
Interferon alpha 4/IFNA4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00829
Species: Human
Expression System: HEK293 Cells
IFNAR1 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02634
Species: Human
Expression System: HEK293 Cells
Interferon alpha 2/IFNA2 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-06407
Species: Human
Expression System: HEK293 Cells
Vaccinia Virus B18R/B19R Protein (His)
Cat.No: TMPY-03758
Species: VACV
Expression System: Baculovirus Insect Cells
Interferon alpha 21/IFNA21 Protein, Human, Recombinant (His)
Cat.No: TMPH-01547
Species: Human
Expression System: E. coli
Interferon alpha 14/IFNA14 Protein, Human, Recombinant (His & SUMO)
Cat.No: TMPH-01544
Species: Human
Expression System: E. coli
Interferon alpha 16/IFNA16 Protein, Human, Recombinant (His)
Cat.No: TMPH-01545
Species: Human
Expression System: E. coli
Interferon alpha 17/IFNA17 Protein, Human, Recombinant (His)
Cat.No: TMPH-01546
Species: Human
Expression System: E. coli
Interferon alpha-G/IFNAG Protein, Bovine, Recombinant (His & SUMO)
Cat.No: TMPH-00276
Species: Bovine
Expression System: E. coli
STAT2 Protein, Human, Recombinant (His)
Cat.No: TMPU-00003
Species: Human
Expression System: E. coli
JAK1 Protein, Human, Recombinant (His)
Cat.No: TMPH-02273
Species: Human
Expression System: P. pastoris (Yeast)
JAK1 Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-02272
Species: Human
Expression System: E. coli
STAT1 Protein, Human, Recombinant
Cat.No: TMPJ-00961
Species: Human
Expression System: E. coli
IL-18R alpha Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00317
Species: Human
Expression System: HEK293 Cells
IL-18R alpha Protein, Cynomolgus, Recombinant (aa 22-329, His)
Cat.No: TMPK-00512
Species: Cynomolgus
Expression System: HEK293 Cells
IL-18R alpha Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00316
Species: Human
Expression System: HEK293 Cells
JAK1 Protein, Mouse, Recombinant (His)
Cat.No: TMPH-02961
Species: Mouse
Expression System: E. coli
VCAM-1 Protein, Mouse, Recombinant (hFc)
Cat.No: TMPJ-00930
Species: Mouse
Expression System: HEK293 Cells
IL-18RAP Protein, Human, Recombinant (hFc & His)
Cat.No: TMPJ-00344
Species: Human
Expression System: HEK293 Cells
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