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基于表型筛选实体化合物活性筛选 细胞增殖检测 细胞周期检测 细胞凋亡检测 药代动力学研究
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细胞因子和生长因子 •   细胞因子 •   生长因子 受体蛋白 •   Fc 受体 •   细胞因子和生长因子受体
CD 蛋白 •   T 细胞 CD 蛋白 •   B 细胞 CD 蛋白 免疫检查点蛋白 •   抑制性免疫检查点蛋白 •   刺激性免疫检查点蛋白
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Search Results for " fgfr4 "
Targets Recommended: FGFR

39

抑制剂 & 化合物

20

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
TQ0256 FGFR4-IN-1

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FGFR4-IN-1 是一种 FGFR4 抑制剂 (IC50:0.7 nM)。
T37425 FGFR4-IN-5

FGFR4-IN-5
FGFR4-IN-5, a covalent FGFR4 inhibitor, demonstrates potency and selectivity with an IC50 value of 6.5 nM. Exhibiting significant in vivo anti-tumor activity, it is applicable for research in hepatocellular carcinoma [1].
T11280 FGFR4-IN-4

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FGFR4-IN-4 is a FGFR4 inhibitor with anti-tumor activity.
T73121 FGFR4-IN-8

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FGFR4-IN-8 (Compound 7v) 是 ATP 竞争性、高选择性的 FGFR4 野生型及其突变体共价抑制剂，对 FGFR4、FGFR4V550L、FGFR4V550M 及 FGFR4C552S 的 IC50 值分别为 0.5、0.25、1.6、931 nM。该化合物能有效抑制 Hep3B 肝细胞癌细胞增殖，显示出显著的抑制效果，具有潜在的临床应用价值。
T64015 FGFR4-IN-6

FGFR4-IN-6 是一种共价的、可逆的 FGFR4 抑制剂 (IC50: 5.4 nM)，表现出良好的口服药代动力学特性。 在 Hep3B2.1-7 HCC 细胞系的异种移植小鼠模型中，FGFR4-IN-6 能够明显诱导肿瘤消退，且无明显的毒性。
T79880 FGFR4-IN-16

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FGFR4-IN-16 (CY-15-2)为FGFR-4选择性共价抑制剂，适用于癌症研究领域。
T63692 FGFR4-IN-7

FGFR4-IN-7 是共价的、可逆的 FGFR4 抑制剂 (IC50: 0.42 μM)，能够阻断 FGFR4 信号通路，进而诱导细胞凋亡 (apoptosis)。FGFR4-IN-7 能够用于研究肝癌 (HCC)。
T63704 FGFR4-IN-11

FGFR4-IN-11 是选择性的、有效的、共价结合的 FGFR4 抑制剂 (IC50: 2.1 nM)。FGFR4-IN-11 能够明显抑制 FGF19/FGFR4 信号通路，表现出抗癌效果。
T62682 FGFR4-IN-10

FGFR4-IN-10 (compound 5a) 是一种选择性的、有效的 FGFR4 抑制剂 (IC50: 70.7 nM)。FGFR4-IN-10 不能抑制其他 FGFR 家族成员 (即 FGFR1、FGFR2 和 FGFR3)。
T63662 FGFR4-IN-9

FGFR4-IN-9 是 FGFR4 的选择性抑制剂 (IC50: 75.3 nM)，能够有效抑制肝癌细胞的生长和血管生成。
T79271 FGFR4-IN-14

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FGFR4-IN-14（Compound 27i）是一种高效的FGFR4抑制剂，IC50值仅为2.4 nM。该化合物能够抑制包含V550L和N535K突变的细胞增殖，且在huh7、BaF3/ETV6-FGFR4-V550L和BaF3/ETV6-FGFR4-N535K细胞系中的IC50分别达到21 nM、2.5 nM和171 nM。在Huh7异种移植模型中，FGFR4-IN-14展现出了明显的抗肿瘤效果，适用于肝细胞癌（HCC）的相关研究。
T4235 Roblitinib

FGF-401

 FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Roblitinib (FGF-401) 是一种口服有效的，高选择性的FGFR4抑制剂(IC50:1.9 nM)，具有抗癌作用。
T3456 Fisogatinib

BLU554,BLU 554,BLU-554

 FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Fisogatinib (BLU-554) 是高效的、选择性的、口服具有活力的 FGFR4 抑制剂(IC50:5 nM)。它在依赖FGFR4信号传导的肝细胞癌模型中具有显著的抗肿瘤活性。
T2347 BLU9931

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
BLU9931 是高度选择性的，不可逆的成纤维细胞生长因子受体 4 抑制剂，其 IC50=3 nM，Kd=6 nM，具有抗肿瘤作用。
T12401 Pemigatinib

INCB054828

 FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Pemigatinib (INCB054828) 是一种口服具有活力的，选择性的 FGFR 抑制剂，能够作用于 FGFR1 (IC50:0.4 nM)，FGFR2 (IC50:0.5 nM)，FGFR3 (IC50:1.2 nM)，FGFR4 (IC50:30 nM)，有用于胆管癌的潜力。
T16364 Infigratinib phosphate

NVP-BGJ398 phosphate,BGJ-398 phosphate

 FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Infigratinib phosphate (BGJ-398 phosphate) 是 FGFR 抑制剂，对 FGFR1，FGFR2 和 FGFR3 的 IC50 分别为0.9，1.4 和 1 nM，比对 FGFR4 和 VEGFR2 的抑制性高40倍，对 Abl，Fyn，Kit，Lck 和 Lyn 几乎无活性。
T6024 Zoligratinib

FF284,CH5183284,Debio 1347

 FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Zoligratinib (CH5183284) 是一种口服具有活力的，选择性的FGFR 抑制剂，能够抑制FGFR1 (IC50:9.3 nM)，FGFR2 (IC50:7.6 nM)，FGFR3 (IC50:22 nM)，FGFR4 (IC50:290 nM)。
T3466 FIIN-3

EGFR; FGFR Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
FIIN-3 是FGFR 的不可逆抑制剂，对FGFR1、FGFR2、FGFR3和FGFR4的IC50值分别为13.1、21、31.4和35.3 nM。
T1975 Infigratinib

BGJ-398,NVP-BGJ398

 Apoptosis; FGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Infigratinib (NVP-BGJ398) 是一种 FGFR 家族抑制剂，抑制 FGFR1，FGFR2，FGFR3和 FGFR4的 IC50分别为 0.9 nM，1.4 nM，1 nM，60 nM。
T7738 H3B-6527

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
H3B-6527 是一种在 FGF19 驱动的肝细胞癌中有效且选择性的 FGFR4 抑制剂，具有抗肿瘤活性。
T2361 LY2874455

LY 2874455,LY-2874455

 VEGFR; FGFR Angiogenesis; Tyrosine Kinase/Adaptors
LY2874455 是pan-FGFR 抑制剂，能够抑制FGFR1 (IC50:2.8 nM)，FGFR2 (IC50:2.6 nM)，FGFR3 (IC50:6.4 nM)，FGFR4 (IC50:6 nM)。
T6836 FIIN-2

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FIIN2 是一种 FGFR 的不可逆抑制剂，能够抑制 FGFR1 (IC50:3.1 nM)，FGFR2 (IC50:4.3 nM)，FGFR3 (IC50:27 nM) 和 FGFR4 (IC50:45 nM)。
TQ0015 PRN1371

c-Fms; FGFR; CSF-1R Angiogenesis; Tyrosine Kinase/Adaptors
PRN1371 是一种高效的、选择性的FGFR1-4和CSF1R 抑制剂，对FGFR1，FGFR2，FGFR3，FGFR4 和 CSF1R 的IC50值分别为 0.6，1.3，4.1，19.3 和 8.1 nM。
T1948 AZD4547

VEGFR; FGFR Angiogenesis; Tyrosine Kinase/Adaptors
AZD4547 是FGFR 家族抑制剂，能够作用于FGFR1 (IC50:0.2 nM)，FGFR2 (IC50:2.5 nM)，FGFR3 (IC50:1.8 nM) 和FGFR4 (IC50:165 nM)。
T37426 FIIN-1

FGFR irreversible inhibitor-1

 FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FIIN-1 (FGFR irreversible inhibitor-1) 是一种不可逆具有选择性的 FGFR 抑制剂，对 FGFR1、FGFR2、FGFR3、FGFR4、 Flt1、Flt14 的 Kd 分别为 2.8、6.9、5.4、120 ，32和120 nM。FIIN-1 对FGFR1、FGFR2、FGFR3和FGFR4 具有抑制作用， IC50 分别是 9.2，6.2，11.9 和 189 nM。
T5473 ASP5878

ASP-5878

 FGFR Angiogenesis; Tyrosine Kinase/Adaptors
ASP5878 是一种 FGFR 1 (IC50:0.47 nM)、FGFR 2 (IC50:0.6 nM)、FGFR 3 (IC50:0.74 nM)、和 FGFR 4 (IC50:3.5 nM)的抑制剂，具有口服活性，具有潜在的抗肿瘤作用。
T79257 FGFR-IN-11

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
FGFR-IN-11（compound I-5）是一款具备口服活性的共价pan-FGFR抑制剂，对FGFR1至FGFR4的IC50值分别为9.9 nM、3.1 nM、16 nM和1.8 nM。该化合物能够在纳摩尔水平有效抑制多种肿瘤细胞的增殖，并在荷瘤小鼠模型中显著地抑制肿瘤生长。
T70258 Roblitinib citrate

Roblitinib citrate is an inhibitor of human fibroblast growth factor receptor 4 (FGFR4) with potential antineoplastic activity.
T3726 Erdafitinib

厄达替尼,JNJ-42756493

 Apoptosis; FGFR Angiogenesis; Apoptosis; Tyrosine Kinase/Adaptors
Erdafitinib (JNJ-42756493) 是一种喹喔啉衍生物，是一种具有口服活性的FGFR 家族抑制剂，抑制FGFR1/2/3/4活性的IC50分别为1.2、 2.5、3.0和5.7 nM。
T73316 FGFR-IN-9

FGFR-IN-9 是一种有效的、可逆的、具有口服活性的FGFR 抑制剂，对FGFR4WT、FGFR3、FGFR4V550L、FGFR2 和FGFR1的IC50分别为 17.1、29.6、30.7、46.7 和 64.3 nM。
T79850 Irpagratinib

ABSK011

 FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Irpagratinib (ABSK011)是一种靶向FGFR4(IC50<10 nM)的口服活性酪氨酸激酶抑制剂，可抑制FGFR4自磷酸化并阻断其信号转导至下游途径。在小鼠、大鼠和狗的PK研究中，Irpagratinib表现出高暴露量，并在皮下异种移植肿瘤模型中展示抗肿瘤活性。
T79871 S6K2-IN-1

FGFR Angiogenesis; Tyrosine Kinase/Adaptors
S6K2-IN-1（化合物2）为S6K2抑制剂（IC50：22 nM），并对FGFR4亦有抑制作用（IC50：216 nM）。该化合物在小鼠肝微粒体中展现出良好的稳定性。
T62653 FGFR-IN-2

FGFR-IN-2 (compound 1) 是一种有效的 FGFR 抑制剂，能够作用于 FGFR1 (IC50: 7.3 nM)、FGFR2 (IC50: 4.3 nM)、FGFR3 (IC50: 7.6 nM) 和 FGFR4 (IC50: 11 nM)。FGFR-IN-2 具有潜力进行癌症研究。
T72749 E7090 succinate

E7090 succinate 是具有口服活性的、选择性的、有效的 FGFR1/2/3抑制剂，其对 FGFR1/2/3/4 的 IC50值分别为 0.71 nM、0.50 nM、1.2 nM 和120 nM。
T73179 HDAC-IN-50

HDAC-IN-50是一种口服活性的有效FGFR和HDAC双重抑制剂，其IC50值针对FGFR1、FGFR2、FGFR3、FGFR4、HDAC1、HDAC2、HDAC6、HDAC8分别为0.18、1.2、0.46、1.4、1.3、1.6、2.6、13 nM。该化合物能诱导(Apoptosis)及使细胞周期在G0/G1期停滞，降低pFGFR1、pERK、pSTAT3的表达，展现出抗肿瘤活性。
T7611 ODM-203

VEGFR; FGFR Angiogenesis; Tyrosine Kinase/Adaptors
ODM-203 是 FGFR 和 VEGFR 家族的抑制剂，具有显著的抗肿瘤活性，能够诱导抗肿瘤免疫。
T83911 CYY292

CYY292是一种针对PDGFRα、PDGFRβ、FGFR1、-2和-3的抑制剂（IC50分别为5.35、4.6、28、28和78 nM）。该化合物对这些激酶的选择性高于FGFR4（IC50 > 1,000 nM），但也能抑制c-Kit、VEGFR2、VEGFR1和胰岛素样生长因子1受体（IGF-1R；IC50分别为67、33、36和75 nM），以及EGFR、布鲁顿酪氨酸激酶（BTK）、细胞周期依赖性激酶4（Cdk4）/cyclin D3和MET（IC50分别为128、198、214和396 nM）。CYY292抑制MG-63、U2OS、MNNG/HOS和Saos-2骨肉瘤细胞的增殖（IC50分别为0.84、0.76、1.36和0.72 µM）。在0.3和0.5 µM的浓度下，它抑制U87MG和LN-229胶质母细胞瘤细胞的迁移和侵袭。CYY292（30 mg/kg）在U87MG原位小鼠异种移植模型中降低肿瘤体积并增加生存率。
T5044 Futibatinib

TAS120,FGFR-IN-1

 FGFR Angiogenesis; Tyrosine Kinase/Adaptors
Futibatinib (FGFR-IN-1) 是口服具有活力的、选择性强的、高生物利用度的、不可逆的 FGFR 抑制剂。它抑制突变型和野生型 FGFR2，且 IC50相似(wild-type FGFR2=0.9 nM; V5651=1-3 nM; N550H=3.6 nM; E566G=2.4 nM)。
T27234 E7090

E-7090,E 7090
E-7090 is a fibroblast growth factor receptor inhibitor. E-7090 is a selective inhibitor of the tyrosine kinase activities of FGFR1, -2, and -3.

化合物

FGFR4-IN-1
Cat.No: TQ0256
Synonym:
Target: FGFR
FGFR4-IN-5
Cat.No: T37425
Synonym: FGFR4-IN-5
Target:
FGFR4-IN-4
Cat.No: T11280
Synonym:
Target: FGFR
FGFR4-IN-8
Cat.No: T73121
Synonym:
Target: FGFR
FGFR4-IN-6
Cat.No: T64015
Synonym:
Target:
FGFR4-IN-16
Cat.No: T79880
Synonym:
Target: FGFR
FGFR4-IN-7
Cat.No: T63692
Synonym:
Target:
FGFR4-IN-11
Cat.No: T63704
Synonym:
Target:
FGFR4-IN-10
Cat.No: T62682
Synonym:
Target:
FGFR4-IN-9
Cat.No: T63662
Synonym:
Target:
FGFR4-IN-14
Cat.No: T79271
Synonym:
Target: FGFR
Roblitinib
Cat.No: T4235
Synonym: FGF-401
Target: FGFR
Fisogatinib
Cat.No: T3456
Synonym: BLU554,BLU 554,BLU-554
Target: FGFR
BLU9931
Cat.No: T2347
Synonym:
Target: FGFR
Pemigatinib
Cat.No: T12401
Synonym: INCB054828
Target: FGFR
Infigratinib phosphate
Cat.No: T16364
Synonym: NVP-BGJ398 phosphate,BGJ-398 phosphate
Target: FGFR
Zoligratinib
Cat.No: T6024
Synonym: FF284,CH5183284,Debio 1347
Target: FGFR
FIIN-3
Cat.No: T3466
Synonym:
Target: EGFR, FGFR
Infigratinib
Cat.No: T1975
Synonym: BGJ-398,NVP-BGJ398
Target: Apoptosis, FGFR
H3B-6527
Cat.No: T7738
Synonym:
Target: FGFR
LY2874455
Cat.No: T2361
Synonym: LY 2874455,LY-2874455
Target: VEGFR, FGFR
FIIN-2
Cat.No: T6836
Synonym:
Target: FGFR
PRN1371
Cat.No: TQ0015
Synonym:
Target: c-Fms, FGFR, CSF-1R
AZD4547
Cat.No: T1948
Synonym:
Target: VEGFR, FGFR
FIIN-1
Cat.No: T37426
Synonym: FGFR irreversible inhibitor-1
Target: FGFR
ASP5878
Cat.No: T5473
Synonym: ASP-5878
Target: FGFR
FGFR-IN-11
Cat.No: T79257
Synonym:
Target: FGFR
Roblitinib citrate
Cat.No: T70258
Synonym:
Target:
Erdafitinib
Cat.No: T3726
Synonym: 厄达替尼,JNJ-42756493
Target: Apoptosis, FGFR
FGFR-IN-9
Cat.No: T73316
Synonym:
Target:
Irpagratinib
Cat.No: T79850
Synonym: ABSK011
Target: FGFR
S6K2-IN-1
Cat.No: T79871
Synonym:
Target: FGFR
FGFR-IN-2
Cat.No: T62653
Synonym:
Target:
E7090 succinate
Cat.No: T72749
Synonym:
Target:
HDAC-IN-50
Cat.No: T73179
Synonym:
Target:
ODM-203
Cat.No: T7611
Synonym:
Target: VEGFR, FGFR
CYY292
Cat.No: T83911
Synonym:
Target:
Futibatinib
Cat.No: T5044
Synonym: TAS120,FGFR-IN-1
Target: FGFR
E7090
Cat.No: T27234
Synonym: E-7090,E 7090
Target:
Species：
Human (10)
Rhesus (3)
Chicken (2)
Mouse (2)
Rat (2)
Rabbit (1)
Expression System：
HEK293 Cells (14)
E. coli (4)
Baculovirus Insect Cells (1)
P. pastoris (Yeast) (1)
Tag：
C-His-Avi (4)
C-His (3)
His (3)
Tag Free (2)
hFc (2)
C-hFc (1)
His, GST (1)
His, hFc (1)
N-10xHis, C-Myc (1)
N-6xHis (1)
Cat. No. Product Name Species Expression System
TMPK-00378 FGFR4 beta Protein, Human, Recombinant (His & Avi)

JTK2,CD334,FGFR4 β,FGF R4

Human HEK293 Cells
FGFR4 beta Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1.
TMPK-00380 FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated

FGFR4,TKF,FGFR4 β,FGF R<...

 Human HEK293 Cells
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1.
TMPY-02112 FGFR4 Protein, Human, Recombinant (His)

TKF,JTK2,CD334,fibroblast growth factor receptor

Human HEK293 Cells
FGFR4 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1.
TMPK-01322 FGFR4 Protein, Rhesus macaque, Recombinant (His)

TKF,JTK2,FGF R4,CD334,FGFR-4<...

 Rhesus HEK293 Cells
FGFR4 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 39.66 kDa and the accession number is XP_028705775.1.
TMPK-00379 FGFR4 Protein, Human, Recombinant (His & Avi)

CD334,FGFR4,TKF,FGF R4,<...

 Human HEK293 Cells
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
TMPK-00381 FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated

CD334,FGFR-4,FGFR4

Human HEK293 Cells
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
TMPY-03683 FGFR4 Protein, Rhesus, Recombinant (His)

fibroblast growth factor receptor 4

 Rhesus HEK293 Cells
FGFR4 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.8 kDa and the accession number is XP_001087243.1.
TMPY-00974 FGFR4 Protein, Mouse, Recombinant (His)

Fgfr-4,fibroblast growth factor receptor <...

 Mouse HEK293 Cells
FGFR4 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is A0A0R4IZY3.
TMPY-02635 FGFR4 Protein, Rat, Recombinant (hFc)

fibroblast growth factor receptor 4

 Rat HEK293 Cells
FGFR4 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is Q498D6.
TMPY-00806 FGFR4 Protein, Human, Recombinant (hFc)

fibroblast growth factor receptor 4,CD334,...

 Human HEK293 Cells
FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is P22455-1.
TMPY-03322 FGFR4 Protein, Rhesus, Recombinant (hFc)

fibroblast growth factor receptor 4

 Rhesus HEK293 Cells
FGFR4 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.6 kDa and the accession number is XP_001087243.1.
TMPY-02862 FGFR4 Protein, Rat, Recombinant (His)

fibroblast growth factor receptor 4

 Rat HEK293 Cells
FGFR4 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.3 kDa and the accession number is Q498D6.
TMPY-01019 FGFR4 Protein, Mouse, Recombinant (His & hFc)

Fgfr-4,fibroblast growth factor receptor <...

 Mouse HEK293 Cells
FGFR4 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67 kDa and the accession number is A0A0R4IZY3.
TMPY-06037 FGFR4 Protein, Human, Recombinant (His), Biotinylated

CD334,TKF,JTK2,fibroblast growth factor receptor

Human HEK293 Cells
FGFR4 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22455-1.
TMPY-02907 FGF-19 Protein, Human, Recombinant

fibroblast growth factor 19,FGF19

 Human E. coli
FGF19, also known as FGF-19, is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF19 interacts with FGFR1, FGFR2, FGFR3 and FGFR4. Affinity between fibroblast growth factors (FGFs) and their receptors is increased by KL, KLB and heparan sulfate glycosaminoglyca...
TMPY-03104 FGF-17 Protein, Human, Recombinant

fibroblast growth factor 17,HH20,FGF-13,FGF-17

 Human E. coli
FGF-13, also known as FGF17, belongs to the fibroblast growth factor (FGF) family. Members of this family show broad mitogenic and cell survival activities, and play a role in a variety of biological processes including embryonic development cell growth, morphogenesis, tissue repair, tumor growth and invasion. FGF-13 is preferentially expressed in the embryonic brain. It interacts with FGFR3 and FGFR4. FGF-13 plays an important role in the regulation of embryonic development and as signaling mol...
TMPH-03203 FGFb Protein, Rabbit, Recombinant (His & SUMO)

Rabbit E. coli
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Binds to integrin ITGAV:ITGB3. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. Mediates phosphorylation of ERK1/2 and thereby promotes retinal lens fiber differentiation. FGFb Protein, Rabbit, Recombinant (His & SUMO) is expressed in E. coli exp...
TMPH-00369 FGF-2 Protein, Chicken, Recombinant (His & Myc)

Chicken E. coli
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 23.8 kDa and the accession number is P48800.
TMPH-00368 FGF-2 Protein, Chicken, Recombinant (His)

Chicken P. pastoris (Yeast)
Acts as a ligand for FGFR1, FGFR2, FGFR3 and FGFR4. Also acts as an integrin ligand which is required for FGF2 signaling. Plays an important role in the regulation of cell survival, cell division, cell differentiation and cell migration. Functions as a potent mitogen in vitro. Can induce angiogenesis. FGF-2 Protein, Chicken, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.3 kDa and the accession number is P48800.
TMPY-02240 STAT1 Protein, Human, Recombinant (His & GST)

IMD31A,IMD31B,IMD31C,STAT91,CANDF7,signal transducer and act...

 Human Baculovirus Insect Cells
STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands, including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. It is a signal transducer and transcription activator that mediates cellular responses to interferons (IFNs),...

重组蛋白

FGFR4 beta Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00378
Species: Human
Expression System: HEK293 Cells
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00380
Species: Human
Expression System: HEK293 Cells
FGFR4 Protein, Human, Recombinant (His)
Cat.No: TMPY-02112
Species: Human
Expression System: HEK293 Cells
FGFR4 Protein, Rhesus macaque, Recombinant (His)
Cat.No: TMPK-01322
Species: Rhesus
Expression System: HEK293 Cells
FGFR4 Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00379
Species: Human
Expression System: HEK293 Cells
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00381
Species: Human
Expression System: HEK293 Cells
FGFR4 Protein, Rhesus, Recombinant (His)
Cat.No: TMPY-03683
Species: Rhesus
Expression System: HEK293 Cells
FGFR4 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00974
Species: Mouse
Expression System: HEK293 Cells
FGFR4 Protein, Rat, Recombinant (hFc)
Cat.No: TMPY-02635
Species: Rat
Expression System: HEK293 Cells
FGFR4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-00806
Species: Human
Expression System: HEK293 Cells
FGFR4 Protein, Rhesus, Recombinant (hFc)
Cat.No: TMPY-03322
Species: Rhesus
Expression System: HEK293 Cells
FGFR4 Protein, Rat, Recombinant (His)
Cat.No: TMPY-02862
Species: Rat
Expression System: HEK293 Cells
FGFR4 Protein, Mouse, Recombinant (His & hFc)
Cat.No: TMPY-01019
Species: Mouse
Expression System: HEK293 Cells
FGFR4 Protein, Human, Recombinant (His), Biotinylated
Cat.No: TMPY-06037
Species: Human
Expression System: HEK293 Cells
FGF-19 Protein, Human, Recombinant
Cat.No: TMPY-02907
Species: Human
Expression System: E. coli
FGF-17 Protein, Human, Recombinant
Cat.No: TMPY-03104
Species: Human
Expression System: E. coli
FGFb Protein, Rabbit, Recombinant (His & SUMO)
Cat.No: TMPH-03203
Species: Rabbit
Expression System: E. coli
FGF-2 Protein, Chicken, Recombinant (His & Myc)
Cat.No: TMPH-00369
Species: Chicken
Expression System: E. coli
FGF-2 Protein, Chicken, Recombinant (His)
Cat.No: TMPH-00368
Species: Chicken
Expression System: P. pastoris (Yeast)
STAT1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-02240
Species: Human
Expression System: Baculovirus Insect Cells
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