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11

抑制剂 & 化合物

27

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T4318	EOC317 ACTB-1003,ACTB1003,ACTB 1003	VEGFR; FGFR; Tie-2	Angiogenesis; Tyrosine Kinase/Adaptors
	EOC317 (ACTB-1003) 是一种口服可用的激酶抑制剂，能够抑制 FGFR1 (IC50:6 nM)，VEGFR2 (IC50:2 nM) 和 Tie-2 (IC50:4 nM)。
T125114	Oleocanthal
	Oleocanthal 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125114。
T125374	Neocryptomerin
	Neocryptomerin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125374。
T19559	Seocalcitol EB 1089	Others	Others
	Seocalcitol is an analog of vitamin D, binds vitamin D receptor protein from human osteosarcoma MG-63 cells(Kd : 0.27 nM).
T124737	Neochlorogenin
	Neochlorogenin 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124737。
T37545	cis-9,10-Methyleneoctadecanoic Acid
	cis-9,10-Methyleneoctadecanoic acid is a cyclopropane fatty acid that has been found in bacteria and the digestive gland of P. globosa. It is a component of S. aureus cell membranes and levels decrease upon treatment with carvacrol. cis-9,10-Methyleneoctadecanoic acid is secreted by H. pylori and enhances histamine- and dibutyryl cAMP-stimulated acid secretion in isolated guinea pig parietal cells. It also activates protein kinase C (PKC) in a calcium-dependent manner.
T126006	Citreochlorol
	Citreochlorol 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T126006，CAS号为 135352-11-3。
T128733	9,10-Methyleneoctadecanoic acid
	9,10-Methyleneoctadecanoic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T128733。
T33631	Neocuproine Neocuproin
	Neocuproine 是一种铜（I）螯合剂，可增强电场刺激引起的输精管收缩的嘌呤能成分，常被用作配位试剂和铜离子检测剂。Neocuproine 与铜离子形成稳定的络合物，并可在某些化学反应和分析方法中起到催化作用。Neocuproine 作为铁和钴上的氧化还原活性配体平台，对NSC34细胞氧化损伤的保护作用。
T16283	Neocarzinostatin	5-HT Receptor	GPCR/G Protein; Neuroscience
	Neocarzinostatin is an effective DNA-damaging, anti-tumor antibiotic. It recognizes double-stranded DNA bulge and induces DNA double strand breaks (DSBs). Neocarzinostatin leads to apoptosis. Neocarzinostatin has potential for EpCAM-positive cancer treatment.
T35604	Osteocalcin (1-49) (human) (trifluoroacetate salt)
	Osteocalcin (1-49) is a non-collagenous peptide that is secreted by osteoblasts and odontoblasts and comprises 1-2% of the total protein in bone. Secretion of osteocalcin (1-49) is stimulated by 1,25-dihydroxy vitamin D and plasma levels increase in diseases that induce dysregulated bone turnover such as osteoporosis, Paget's disease, and primary hyperparathyroidism. Osteocalcin (1-49) is positively correlated with insulin sensitivity and negatively correlated with high blood glucose levels in w...

化合物

Cat.No: T4318

Synonym: ACTB-1003,ACTB1003,ACTB 1003

Target: VEGFR, FGFR, Tie-2

Cat.No: T125114

Cat.No: T125374

Cat.No: T19559

Synonym: EB 1089

Target: Others

Cat.No: T124737

cis-9,10-Methyleneoctadecanoic Acid

Cat.No: T37545

Cat.No: T126006

9,10-Methyleneoctadecanoic acid

Cat.No: T128733

Cat.No: T33631

Synonym: Neocuproin

Neocarzinostatin

Cat.No: T16283

Target: 5-HT Receptor

Osteocalcin (1-49) (human) (trifluoroacetate salt)

Cat.No: T35604

Cat. No.	Product Name	Target	Signaling Pathways
T5S1882	Songorine 准葛尔乌头碱,Napellonine,Zongorine,Bullatine G	Others; GABA Receptor	Membrane transporter/Ion channel; Neuroscience; Others
	Songorine (Napellonine) 是从乌头属中分离出的一种二萜生物碱，具有抗癌、抗心律不齐和抗炎活性。它是大鼠脑中的GABAA 受体拮抗剂，有用于上皮性卵巢癌的研究潜力。
TN1979	Neocnidilide 新蛇床内酯,新蛇床内酯,新川芎内酯	Antifungal	Microbiology/Virology
	Neocnidilide 是一种从川芎中提取的烷基邻苯二甲酸酯，具有抑制产生真菌毒素的真菌生长和杀虫。Neocnidilide 对 D. melanogaster 幼虫的LC50 值为 9.9 μmol/mL。它可以增强苯甲酸的皮肤渗透性。
TN5845	Neochlorogenic acid methyl ester 5-O-Caffeoylquinic acid methyl ester,Methyl 3-caffeoylquinate,GIP (1-39) acetate(725474-97-5 Free base),Methyl neochlorogenate,新绿原酸甲酯	Antioxidant; HBV	Microbiology/Virology; oxidation-reduction
	Neochlorogenic acid methyl ester (5-O-Caffeoylquinic acid methyl ester) 来源于毛蒿和黑色苦莓(Aronia melanocarpa)果实。Neochlorogenic acid methyl ester 显示出抗 HBV 活性、抗氧化活性和醌还原酶活性，CD 为 6.7 μM。
TN6797	Isoneochamaejasmin A	Others	Others
	Isoneochamaejasmin A 是一种双黄酮类化合物，是一种广泛使用的中药 stellera chamaejasme L. 干燥根中的主要活性成分之一。
TN1977	Neochamaejasmine B 新狼毒素B	Antifection	Microbiology/Virology
	Neochamaejasmin B 是一种提取自Stellera chamaejasme L.的双黄酮化合物。它在 C-2/C-3 和 C-2″/C-3″ 位置具有顺反几何结构。
T6S1538	Neochlorogenic acid 新绿原酸,trans-5-O-Caffeoylquinic acid,Neochlorogenate,金银花,5-O-Caffeoylquinic acid	TNF; NF-κB; COX; Antibacterial; Interleukin	Apoptosis; Immunology/Inflammation; Microbiology/Virology; Neuroscience; NF-κB
	Neochlorogenic acid (trans-5-O-Caffeoylquinic acid) 是在干果和其他植物中发现的一种多酚类天然产物，可抑制iNOS 和COX-2蛋白表达，抑制TNF-α和IL-1β产生，还抑制磷酸化的NF-κB p65和p38 MAPK 活化。
TN6324	Neochlorogenin 6-O-β-D-xylopyranosyl-(1→3)-β-D-quinovopyranoside
	Neochlorogenin 6-O-β-D-xylopyranosyl-(1→3)-β-D-quinovopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6324，CAS号为 184686-02-0。
TN6326	Neochlorogenin 6-O-α-L-rhamnopyranosyl-(1→3)-β-D-quinovopyranoside
	Neochlorogenin 6-O-α-L-rhamnopyranosyl-(1→3)-β-D-quinovopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6326，CAS号为 184686-01-9。
T16361	Nucleocidin NSC 521007,4'-Fluoro-5'-O-sulfamoyladenosine	NADPH	Metabolism
	Nucleocidin, an antitrypanosomal antibiotic, inhibits the transfer of labeled amino acids from S-RNA to protein.
TN6318	Neochlorogenin 6-O-β-D-quinovopyranoside
	Neochlorogenin 6-O-β-D-quinovopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6318，CAS号为 711025-86-4。
TN5602	Neocaesalpin L
	Neocaesalpin L is a natural product from Caesalpinia minax HANCE.
TN4633	Neocryptotanshinone II	NOS; NF-κB	Immunology/Inflammation; NF-κB
	Neocryptotanshinone inhibits lipopolysaccharide-induced inflammation in RAW264.7 macrophages by suppression of NF-ÎºB and iNOS signaling pathways.
TN6633	Methyl neochebulinate
	Methyl neochebulinate 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6633，CAS号为 1236310-34-1。
T83565	(2E)-Leocarpinolide F
	（2E）-Leocarpinolide F（化合物20），为从Sigesbeckia orientalis中提取的香叶鹤型倍半萜。
TN3242	7-O-Acetylneocaesalpin N	Others	Others
	7-O-Acetylneocaesalpin N 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3242，CAS号为 1309079-08-0。
TN5599	12-Demethylneocaesalpin F
	12-Demethylneocaesalpin F 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5599，CAS号为 1228964-10-0。
TN5601	Neocaesalpin O
	Neocaesalpin O is a natural product from Caesalpinia minax HANCE.
T81691	Neochilenin 3-O-Methylquercetin 4′-O-glucoside
	Neochilenin (3-O-Methylquercetin 4'-O-glucoside) 是一种从蜡菊亚科 (Cactaceae) 分离出的3-O-methylquercetin糖苷。
T81690	Neocucurbitacin A	STAT	JAK/STAT signaling; Stem Cells
	Neocucurbitacin A (compound 7)是一种从沉香果皮提取的STAT3抑制剂，常用于抗癌研究。
TN1980	Neocryptotanshinone	Others	Others
	Neocryptotanshinone inhibits rabbit platelet aggregation induced by arachidonic acid.
TN6418	7-Methoxyneochamaejasmine A
	7-Methoxyneochamaejasmine A has a strong inhibitory effect on Festuca rubra L. and Medicago sativa seedlings.
T81498	Phaeocaulisin E
	Phaeocaulisin E (Compound 5)，一种愈蓝烷型倍半萜类化合物，具有抑制LPS诱导的RAW 264.7巨噬细胞中NO生成的活性，其IC50值为10.3 μM。
T81941	Leocarpinolide F
	Leocarpinolide F，一天然提取自Siegesbeckia orientalis的类倍半萜烯。
TN1978	Neochebulagic acid 新诃黎勒酸	Others	Others
	Neochebulagic acid is a natural product
TMA0918	Neochamaejasmine A	Caspase	Apoptosis; Proteases/Proteasome
	Neochamaejasmin A can inhibit cellular (3)H-thymidine incorporation (IC 50 12.5 microg/mL) and subsequent proliferation of human prostate cancer LNCaP cells, it blocks cell cycle progression at the G1 phase by activating the p21 protein and ultimately pro
TN4634	Neocyclomorusin	Antifection	Microbiology/Virology
	Neocyclomorusin displays minimal inhibitory concentration (MIC) value of 4 ug/mL against Klebsiella pneumoniae ATCC11296, Enterobacter cloacae BM47.
T5S0167	Atractylenolide I 白术内酯 I,白术内酯I；苍术内酯I	IL Receptor; TNF; TLR; JAK; STAT	Angiogenesis; Apoptosis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Stem Cells
	Atractylenolide I 是从白术根中得到的一种倍半萜烯，具有神经保护、抗过敏、抗炎和抗癌等多种生物活性。它是一种TLR4拮抗剂，在 A375 细胞中，能够降低JAK2和STAT3的磷酸化水平。

天然产物

Cat.No: T5S1882

Synonym: 准葛尔乌头碱,Napellonine,Zongorine,Bullatine G

Target: Others, GABA Receptor

Cat.No: TN1979

Synonym: 新蛇床内酯,新蛇床内酯,新川芎内酯

Target: Antifungal

Neochlorogenic acid methyl ester

Cat.No: TN5845

Synonym: 5-O-Caffeoylquinic acid methyl ester,Methyl 3-caffeoylquinate,GIP (1-39) acetate(725474-97-5 Free base),Methyl neochlorogenate,新绿原酸甲酯

Target: Antioxidant, HBV

Isoneochamaejasmin A

Cat.No: TN6797

Target: Others

Neochamaejasmine B

Cat.No: TN1977

Synonym: 新狼毒素B

Target: Antifection

Neochlorogenic acid

Cat.No: T6S1538

Synonym: 新绿原酸,trans-5-O-Caffeoylquinic acid,Neochlorogenate,金银花,5-O-Caffeoylquinic acid

Target: TNF, NF-κB, COX, Antibacterial, Interleukin

Neochlorogenin 6-O-β-D-xylopyranosyl-(1→3)-β-D-quinovopyranoside

Cat.No: TN6324

Neochlorogenin 6-O-α-L-rhamnopyranosyl-(1→3)-β-D-quinovopyranoside

Cat.No: TN6326

Cat.No: T16361

Synonym: NSC 521007,4'-Fluoro-5'-O-sulfamoyladenosine

Target: NADPH

Neochlorogenin 6-O-β-D-quinovopyranoside

Cat.No: TN6318

Cat.No: TN5602

Neocryptotanshinone II

Cat.No: TN4633

Target: NOS, NF-κB

Methyl neochebulinate

Cat.No: TN6633

(2E)-Leocarpinolide F

Cat.No: T83565

7-O-Acetylneocaesalpin N

Cat.No: TN3242

Target: Others

12-Demethylneocaesalpin F

Cat.No: TN5599

Cat.No: TN5601

Cat.No: T81691

Synonym: 3-O-Methylquercetin 4′-O-glucoside

Neocucurbitacin A

Cat.No: T81690

Target: STAT

Neocryptotanshinone

Cat.No: TN1980

Target: Others

7-Methoxyneochamaejasmine A

Cat.No: TN6418

Phaeocaulisin E

Cat.No: T81498

Leocarpinolide F

Cat.No: T81941

Neochebulagic acid

Cat.No: TN1978

Synonym: 新诃黎勒酸

Target: Others

Neochamaejasmine A

Cat.No: TMA0918

Target: Caspase

Neocyclomorusin

Cat.No: TN4634

Target: Antifection

Atractylenolide I

Cat.No: T5S0167

Synonym: 白术内酯 I,白术内酯I；苍术内酯I

Target: IL Receptor, TNF, TLR, JAK, STAT

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