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39

抑制剂 & 化合物

19

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
TP1931L1	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)	cholecystokinin	GPCR/G Protein
	[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate ([D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate (96736-12-8 free base)) 是广谱神经肽反向激动剂和拮抗剂。 ghrelin 受体的强效完全反向激动剂(EC50 = 5.2 nM)；减少组成型生长素释放肽受体信号传导。它也是速激肽、缓激肽、CCK 和铃蟾肽受体的拮抗剂。在体外诱导细胞凋亡并抑制癌细胞生长。
T37436	C12-Ceramide N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine
	C12-Ceramide (C12 Ceramide (d18:1/12:0)) 是一种存在于先兆子痫妇女所生婴儿围绕脐带血管的保护膜的神经酰胺，是 C12 鞘磷脂被酸性鞘磷脂酶（ASM）水解后形成的，可用于评估 A 型或 B 型尼曼-皮克病患者血浆中的 ASM 活性水平。
T9691L	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate	Thyroid hormone receptor(THR)	Endocrinology/Hormones
	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate 是一种高效的甲状旁腺激素 (PTH) 拮抗剂，在牛肾皮质膜中的 Ki 值为 69 nM。
TP2239L	[D-Phe12]-Bombesin acetate [D-Phe12]-Bombesin acetate(108437-87-2 free base)	Bombesin Receptor	GPCR/G Protein
	[D-Phe12]-Bombesin acetate 抑制铃蟾素刺激的分泌。
TP1916L1	[D-Phe12,Leu14]-Bombesin acetate [D-Phe12,Leu14]-Bombesin acetate(108437-88-3 Free base)	Bombesin Receptor	GPCR/G Protein
	[D-Phe12,Leu14]-Bombesin acetate 抑制铃蟾素刺激的分泌。
T10458	Banoxantrone (D12) Banoxantrone D12,AQ4N D12	Others	Others
	Banoxantrone D12 (AQ4N D12) is the deuterium-labeled Banoxantrone. Banoxantrone is a bioreductive agent that can be reduced to a stable, DNA-affinity compound AQ4, which is a topoisomerase II inhibitor.
TP2239	[D-Phe12]-Bombesin	Others	Others
	Bombesin receptor antagonist
TP1916	[D-Phe12,Leu14]-Bombesin
	Bombesin receptor antagonist that inhibits bombesin binding to rat brain with an IC50 value of 2 μM. Inhibits amylase release in vitro (IC50 = 4 μM) and attenuates bombesin-mediated suppression of food intake in vivo.
T24046	WNK-IN-11-d3 WNK inhibitor-12,WNKIN12,WNK IN 12,WNK inhibitor 12,WNK-IN-12
	WNK-IN-12 is an effective, selective, and orally active WNK1 kinase inhibitor.
T9691	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)
	(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) 在生命科学相关研究中具有广泛的应用。
T13185	Topiramate D12 RWJ 17021 D12,McN 4853 D12	Others	Others
	Topiramate D12 is a deuterium labeled Topiramate. Topiramate is an agent of broad-spectrum antiepileptic. Topiramate is an antagonist of GluR5 receptor.
T19201	Banoxantrone-d12 dihydrochloride AQ4N D12 dihydrochloride	Others	Others
	Banoxantrone D12 (AQ4N D12) dihydrochloride is the deuterium-labeled Banoxantrone. Banoxantrone is a bioreductive agent that can be reduced to a stable, DNA-affinity compound AQ4, which is a topoisomerase II inhibitor.
T76612	(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide
	(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide (Compound 4) 是一种生长抑素类似物，对 SSTR5、SSTR3、SSTR2、SSTR1和 SSTR4的Kd 分别为 0.61、11.05、23.5、1200 和 >1000 nM。
T76602	(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)
	(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat) 作为一种CRF拮抗剂，能有效阻断IL-1a诱发的黄体生成素 (LH) 抑制作用。
T36648	Tucatinib hemiethanolate
	Tucatinib (Irbinitinib) hemiethanolate is a potent, orally active and selective HER2 inhibitor with an IC50 of 8 nM. Tucatinib hemiethanolate has nanomolar activity against purified HER2 enzyme and is approximately 500-fold selective for HER2 versus EGFR in cell-based assays. Tucatinib selectively inhibits the receptor tyrosine kinase HER2 relative to EGFR[1].Tucatinib blocks proliferation and the phosphorylation of HER2 and its downstream effector, Akt in HER2 overexpressing cell lines. In the ...
T35689	MTP 131 acetate	Others	Others
	MTP 131 acetate 是一种小的线粒体靶向四肽。
T64916	D(-)-Norvaline
	D(-)-Norvaline 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64916，CAS号为 2013-12-9。
T66872	(tert-Butoxycarbonyl)-D-cysteine
	(tert-Butoxycarbonyl)-D-cysteine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66872，CAS号为 149270-12-2。
T65254	N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine
	N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65254，CAS号为 50913-12-7。
T66686	n-Heptyl β-D-glucopyranoside
	n-Heptyl β-D-glucopyranoside 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66686，CAS号为 78617-12-6。
T65722	N-Boc-cis-4-Hydroxy-D-proline
	N-Boc-cis-4-Hydroxy-D-proline 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65722，CAS号为 135042-12-5。
T66743	Boc-4-tert-butyl-D-Phe-OH
	Boc-4-tert-butyl-D-Phe-OH 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66743，CAS号为 250611-12-2。
TF0087	n-Tridecyl-β-D-Maltopyranoside
	n-Tridecyl-β-D-Maltopyranoside 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 TF0087，CAS号为 93911-12-7。
T37010	D-threo Sphinganine (d18:0) D-threo Sphinganine (d18:0)
	D-threo Sphinganine (d18:0) is a synthetic bioactive sphingolipid and stereoisomer of sphinganine (d18:0) and L-erythro sphinganine (d18:0) . It induces autophagy in HCT116 cells when used at a concentration of 12 μM. D-threo Sphinganine (d18:0) is metabolized via sphinganine N-acyltransferase and sphinganine kinase in vivo in rat liver.
T66382	1-((2'-Carboxy-[1,1'-biphenyl]-4-yl)methyl)-4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylic acid
	1-((2'-Carboxy-[1,1'-biphenyl]-4-yl)methyl)-4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylic acid 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66382，CAS号为 884330-12-5。
T11269	FD-IN-1	Others	Others
	FD-IN-1 is a factor D (FD) inhibitor with an IC50 of 12 nM.FD-IN-1 also inhibits factor XIa (FXIa) and Tryptase β2 with IC50s of 7.7 and 6.5μM, respectively. Complement FD, a highly specific S1 serine protease, plays a central role in the alternative complement pathway of the innate immune system.
T37565	C6 D-threo Ceramide (d18:1/6:0) C6 D-threo Ceramide (d18:1/6:0)
	C6 D-threo Ceramide is a bioactive sphingolipid and cell-permeable analog of naturally occurring ceramides., C6 D-threo Ceramide is cytotoxic to U937 cells in vitro (IC50 = 18 μM). It is metabolically inactive and, unlike C6 L-erythro ceramide , C6 D-threo ceramide cannot be converted to C6 glucosylceramide by ceramide glucosyltransferase. C6 D-threo Ceramide promotes survival of isolated rat spinal neurons when used at concentrations up to 2.5 μM but induces cell death at concentrations greater...
T78508	Delmitide acetate RDP-58 acetate	IFNAR	Immunology/Inflammation
	Delmitide acetate (RDP58) 是一种 d-异构体十肽，具有抗炎活性和口服活性。该化合物能够抑制 TNF-α、IFN-γ 以及白细胞介素 (IL)-12 的生成，同时提高血红素加氧酶 1 的活性，可用于针对溃疡性结肠炎的研究。
T81451	PKCd (8-17)
	PKCd (8-17) 是源自蛋白激酶 C (PKC)d V1 结构域的生物活性肽。它能抑制由佛波醇 12-肉豆蔻酸酯 13-乙酸酯 (PMA) 诱导的 PKCd 易位和激活。此外，PKCd (8-17) 在降低心脏和脑细胞缺血损伤、促进成纤维细胞增殖、以及抑制小鼠移植冠状动脉疾病方面具有潜在应用。
T35683	2-deoxy-D-Glucose-13C6 2-deoxy-D-Glucose-13C6
	2-deoxy-D-Glucose-13C6is intended for use as an internal standard for the quantification of 2-deoxy-D-glucose by GC- or LC-MS. 2-deoxy-D-Glucose is a glucose antimetabolite and an inhibitor of glycolysis.1,2It inhibits hexokinase, the enzyme that converts glucose to glucose-6-phosphate, as well as phosphoglucose isomerase, the enzyme that converts glucose-6-phosphate to fructose-6-phosphate.32-deoxy-D-Glucose (16 mM) induces apoptosis in SK-BR-3 cells, as well as inhibits the growth of 143B oste...
T37540	Amycolatopsin B
	Amycolatopsin B is a bacterial metabolite originally isolated fromAmycolatopsisthat has anticancer activity.1It is cytotoxic to NCI H460 lung and SW620 colon cancer cells (IC50s = 0.28 and 0.14 μM, respectively). 1.Khalil, Z.G., Salim, A.A., Vuong, D., et al.Amycolatopsins A-C: Antimycobacterial glycosylated polyketide macrolides from the Australian soil Amycolatopsis sp. MST-108494J. Antibiot. (Tokyo)70(12)1097-1103(2017)
T35560	SAR502250
	SAR502250 is a potent, selective, ATP competitive, orally active and brain-penetrant inhibitor of GSK3, with an IC50 of 12 nM for human GSK-3β. SAR502250 displays antidepressant-like activity. SAR502250 can be used for the research of Alzheimer’s disease (AD)[1][2]. SAR502250 (0.01-1 μM; 36 h) attenuates the Aβ25-35-induced cell death in rat embryonic hippocampal neurons[2]. SAR502250 (1-100 mg/kg; a single p.o,) attenuates tau hyperphosphorylation in the cortex and spinal cord of transgenic mic...
T35840	4-Amino-6-chloro-1,3-benzenedisulfonamide
	4-Amino-6-chloro-1,3-benzenedisulfonamide is a carbonic anhydrase inhibitor.1 Formulations containing this compound are diuretics.2 4-Amino-6-chloro-1,3-benzenedisulfonamide is detected as a hydrolysis product of chlorothiazide in the urine.2 Diuretics, including chlorothiazide, have been abused as performance-enhancing drugs and masking agents in sports doping.3References1. Nishimori, I., Vullo, D., Minakuchi, T., et al. Carbonic anhydrase inhibitors: Cloning and sulfonamide inhibition studies ...
T37541	Amycolatopsin C
	Amycolatopsin C is a polyketide macrolide originally isolated fromAmycolatopsisthat has antimycobacterial and anticancer activities.1It is active againstM. bovisandM. tuberculosis(IC50s = 2.7 and 5.7 μM, respectively) but notB. subtilis,S. aureus,E. coli, orP. aeruginosa(IC50s = >30 μM for all). Amycolatopsin C is cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 10 and 5.9 μM, respectively). 1.Khalil, Z.G., Salim, A.A., Vuong, D., et al.Amycolatopsins A-C: Antimycobacterial ...
T37539	Amycolatopsin A
	Amycolatopsin A is a macrolide polyketide originally isolated fromAmycolatopsisthat has antimycobacterial and anticancer activities.1It is active againstM. bovisandM. tuberculosis(IC50s = 0.4 and 4.4 μM, respectively) but notB. subtilis,S. aureus,E. coli, orP. aeruginosa(IC50s = >30 μM for all). Amycolatopsin A is cytotoxic to SW620 colorectal and NCI H460 lung cancer cells (IC50s = 0.08 and 1.2 μM, respectively). 1.Khalil, Z.G., Salim, A.A., Vuong, D., et al.Amycolatopsins A-C: Antimycobacteria...
T35519	Aflatoxin B2-13C17 Aflatoxin B2-13C17
	Aflatoxin B2-13C17(AFB2-13C17) is intended for use as an internal standard for the quantification of AFB2by GC- or LC-MS. AFB2is a mycotoxin that has been found inA. terricola.1It induces hepatic autophagy and apoptosis in broiler chickens when administered at doses of 0.2, 0.4, and 0.8 mg/kg.2AFB2(0.5 and 1 mg/animal) also induces parenchymal cell hyperplasia in rats.3 1.Moubasher, A.H., el-Kady, I.A., and Shoriet, A.Toxigenic Aspergilli isolated from different sources in EgyptAnn. Nutr. Alimen...
T38286	C26 Sphingomyelin (d18:1/26:0) C26 Sphingomyelin (d18:1/26:0)
	C26 Sphingomyelin is a sphingolipid that has been found in serum and cell or brain extracts.1,2,3C26 sphingomyelin levels are increased in the serum of patients with hemophagocytic lymphohistiocytosis, an inflammatory condition characterized by excessive immune activation.3C26 sphingomyelin has been used a component of monolayers to study the influence of sphingomyelin acyl chain length on sphingomyelin-sterol interactions.4[Matreya, LLC.] 1.Wang, J.-R., Zhang, H., Yau, L.D., et al.Improved sphi...
T36215	17R(18S)-EpETE
	17R(18S)-EpETE is an oxylipin and a cytochrome P450 metabolite of eicosapentaenoic acid .1,217R(18S)-EpETE is an activator of large-conductance calcium-activated potassium (BKCa) channels, increasing the potassium current amplitude by 15-fold in isolated rat cerebral artery vascular smooth muscle cells (VSMCs) at +60 mV when used at a concentration of 50 nM.2It has negative chronotropic effects in isolated neonatal rat cardiomyocytes (NRCMs; EC50= ~1-2 nM) and prevents calcium-induced increases ...
T37847	Zonisamide-13C2,15N Zonisamide-13C2,15N
	Zonisamide-13C2,15N is intended for use as an internal standard for the quantification of zonisamide by GC- or LC-MS. Zonisamide is an antiepileptic agent.1 It selectively inhibits the repeated firing of sodium channels (IC50 = 2 μg/ml) in mouse embryo spinal cord neurons and inhibits spontaneous channel firing when used at concentrations greater than 10 μg/ml.2 In rat cerebral cortex neurons, zonisamide (1-1,000 μM) inhibits T-type calcium channels with a maximum reduction of 60% of the calcium...

化合物

[D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate

Cat.No: TP1931L1

Synonym: [D-Arg1,D-Phe5,D-Trp7,9,Leu11]-Substance P acetate(96736-12-8 free base)

Target: cholecystokinin

Cat.No: T37436

Synonym: N-Laurylsphingosine,C12 Ceramide (d18:1/12:0),N-Lauroyl-D-erythro-sphingosine

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine) acetate

Cat.No: T9691L

Target: Thyroid hormone receptor(THR)

[D-Phe12]-Bombesin acetate

Cat.No: TP2239L

Synonym: [D-Phe12]-Bombesin acetate(108437-87-2 free base)

Target: Bombesin Receptor

[D-Phe12,Leu14]-Bombesin acetate

Cat.No: TP1916L1

Synonym: [D-Phe12,Leu14]-Bombesin acetate(108437-88-3 Free base)

Target: Bombesin Receptor

Banoxantrone (D12)

Cat.No: T10458

Synonym: Banoxantrone D12,AQ4N D12

Target: Others

[D-Phe12]-Bombesin

Cat.No: TP2239

Target: Others

[D-Phe12,Leu14]-Bombesin

Cat.No: TP1916

Cat.No: T24046

Synonym: WNK inhibitor-12,WNKIN12,WNK IN 12,WNK inhibitor 12,WNK-IN-12

(D-Trp12,Tyr34)-pTH (7-34) amide (bovine)

Cat.No: T9691

Cat.No: T13185

Synonym: RWJ 17021 D12,McN 4853 D12

Target: Others

Banoxantrone-d12 dihydrochloride

Cat.No: T19201

Synonym: AQ4N D12 dihydrochloride

Target: Others

(D-Phe5,Cys6,11,N-Me-D-Trp8)-Somatostatin-14 (5-12) amide

Cat.No: T76612

(D-Phe12,Nle21,38,α-Me-Leu37)-CRF (12-41) (human, rat)

Cat.No: T76602

Tucatinib hemiethanolate

Cat.No: T36648

MTP 131 acetate

Cat.No: T35689

Target: Others

Cat.No: T64916

(tert-Butoxycarbonyl)-D-cysteine

Cat.No: T66872

N2-(tert-Butoxycarbonyl)-Nw-nitro-D-arginine

Cat.No: T65254

n-Heptyl β-D-glucopyranoside

Cat.No: T66686

N-Boc-cis-4-Hydroxy-D-proline

Cat.No: T65722

Boc-4-tert-butyl-D-Phe-OH

Cat.No: T66743

n-Tridecyl-β-D-Maltopyranoside

Cat.No: TF0087

D-threo Sphinganine (d18:0)

Cat.No: T37010

Synonym: D-threo Sphinganine (d18:0)

1-((2'-Carboxy-[1,1'-biphenyl]-4-yl)methyl)-4-methyl-2-propyl-1H-benzo[d]imidazole-6-carboxylic acid

Cat.No: T66382

Cat.No: T11269

Target: Others

C6 D-threo Ceramide (d18:1/6:0)

Cat.No: T37565

Synonym: C6 D-threo Ceramide (d18:1/6:0)

Delmitide acetate

Cat.No: T78508

Synonym: RDP-58 acetate

Target: IFNAR

Cat.No: T81451

2-deoxy-D-Glucose-13C6

Cat.No: T35683

Synonym: 2-deoxy-D-Glucose-13C6

Amycolatopsin B

Cat.No: T37540

Cat.No: T35560

4-Amino-6-chloro-1,3-benzenedisulfonamide

Cat.No: T35840

Amycolatopsin C

Cat.No: T37541

Amycolatopsin A

Cat.No: T37539

Aflatoxin B2-13C17

Cat.No: T35519

Synonym: Aflatoxin B2-13C17

C26 Sphingomyelin (d18:1/26:0)

Cat.No: T38286

Synonym: C26 Sphingomyelin (d18:1/26:0)

Cat.No: T36215

Zonisamide-13C2,15N

Cat.No: T37847

Synonym: Zonisamide-13C2,15N

Cat. No.	Product Name	Target	Signaling Pathways
TN5897	12-O-Methylinophyllum D
	12-O-Methylinophyllum D 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5897，CAS号为 40883-10-1。
TN1187	12-Hydroxyganoderic acid D 12-羟基灵芝酸 D,12-羟基灵芝酸D	Others	Others
	12-Hydroxyganoderic acid D is a natural product
TN6719	Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside	Others	Others
	Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside 是一种从阿拉伯茉莉中分离出来的天然产物。
TN6493	19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene
	19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene是一种天然产物，属于松科松属，其产品编号为 TN6493，CAS号为 1011714-20-7。19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene可用作对照参考。
TN6776	Cyaonoside B Cyaonoside B,川牛膝皂苷B	Others	Others
	Cyaonoside B 是一种皂苷，有一个葡萄糖醛酸连接到碳 C-3，能够从单胞菌中分离。
TN6734	Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside,槲皮素-3-O-葡萄糖基-(1-2)-L-鼠李糖苷,槲皮素 3-O-葡萄糖基 (1→2)鼠李糖苷	Others	Others
	Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside (Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside) 是 Shuxuenin 中的一种主要抗氧化剂。
TN4607	Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside	Others	Others
	Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4607，CAS号为 142449-93-2。
T83579	(12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-one
	(12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-one为cladosporium微生物[1]中发现的天然化合物。
T3889	Platycodin D	Prostaglandin Receptor; AMPK	Chromatin/Epigenetic; GPCR/G Protein; Immunology/Inflammation; PI3K/Akt/mTOR signaling
	Platycodin D 是从桔梗中分离得到的一种皂苷类天然产物，是AMPKα的激活剂，具有抗肥胖活性。它可刺激 TNF-α 合成或抑制 TNF-α mRNA 的降解。
T36914	2-Hydroxyanthraquinone	Others	Others
	2-Hydroxyanthraquinone 是一种天然产物，显示出抗肿瘤和免疫抑制活性。
TN4216	Hispidulin 4'-O-β-D-glucopyranoside Hispidulin 4'-O-beta-D-glucopyranoside	Others	Others
	Hispidulin 4'-O-β-D-glucopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4216，CAS号为 244285-12-9。
TN4052	Farrerol 7-O-β-D-glucopyranoside Farrerol 7-O-glucoside	Others	Others
	Farrerol 7-O-β-D-glucopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN4052，CAS号为 885044-12-2。
TN5753	Benzyl β-D-glucopyranoside 苄基-β-D-葡萄糖苷,Benzyl glucoside
	Benzyl β-D-glucopyranoside 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN5753，CAS号为 4304-12-5。
T72172	4,6-O-Ethylidene-α-D-glucose Ethylidene-glucose
	4,6-O-ethylidene-α-D-glucose (Ethylidene-glucose) 是一种葡萄糖衍生物，是竞争性的葡萄糖转运蛋白 1 (GLUT1) 面部结合部位抑制剂，对野生型 2-脱氧-D-葡萄糖转运的 Ki 值为 12 mM。
T19329	Fructo-oligosaccharide DP12/GF11 蔗果十二糖	Others	Others
	Fructo-oligosaccharide DP12/GF11 is a member of fructooligosaccharides (FOS) characterized by a degree of polymerization (DP) of 12. FOS compounds consist of 11 fructose units connected by (2→1)-β-glycosidic bonds, with a lone D-glucosyl unit located at the non-reducing end.
T75567	Cabenoside D
	Cabenoside D（化合物 8）是从苔藓根的甲醇提取物中分离的一种三萜苷，显示出对12-O-十四烷酰基激素-13-乙酸酯（TPA）诱导的小鼠炎症的抗炎活性，并能抑制TPA促使的Epstein-Barr病毒（EBV）早期抗原（EBV-EA）激活。
TN4683	Nyasol	ERK; IL Receptor; IκB/IKK; NOS; NF-κB; Akt; Antifection	Cytoskeletal Signaling; Immunology/Inflammation; MAPK; Microbiology/Virology; NF-κB; PI3K/Akt/mTOR signaling
	Nyasol may have potential to be developed as medicines for the treatment of allergies by inhibiting the activation of mast cells. Nyasol shows anti-inflammatory properties by inhibiting iNOS expression; it also has antifungal activity, it is significantly
T37272	9(S),12(S),13(S)-TriHOME
	9(S),12(S),13(S)-TriHOME is a linoleic acid-derived oxylipin that has diverse biological activities.1,2,3,4It has been found in various plants and is produced in human eosinophils in a 15-lipoxygenase-dependent, soluble epoxide hydrolase-independent manner.1,59(S),12(S)13(S)-TriHOME inhibits antigen-induced β-hexosaminidase release from RBL-2H3 mast cells (IC50= 28.7 μg/ml).2It inhibits LPS-induced nitric oxide (NO) production in BV-2 microglia (IC50= 40.95 μM).3In vivo, 9(S),12(S),13(S)-TriHOME...
T36954	Nemorosone
	Nemorosone is a polycyclic polyprenylated acylphloroglucinol (PPAP) originally isolated from C. rosea that has antiproliferative properties.1 Nemorosone inhibits growth of NB69, Kelly, SK-N-AS, and LAN-1 neuroblastoma cells (IC50s = 3.1-6.3 μM), including several drug-resistant clones, but not MRC-5 human embryonic fibroblasts (IC50 = >40 μM).2 It increases DNA fragmentation in LAN-1 cells in a dose-dependent manner, and decreases N-Myc protein levels and phosphorylation of ERK1/2 by MEK1/2. Nem...

天然产物

12-O-Methylinophyllum D

Cat.No: TN5897

12-Hydroxyganoderic acid D

Cat.No: TN1187

Synonym: 12-羟基灵芝酸 D,12-羟基灵芝酸D

Target: Others

Kaempferol-3-O-β-D-glucosyl(1-2)rhamnoside

Cat.No: TN6719

Target: Others

19-O-beta-D-carboxyglucopyranosyl-12-O-beta-D-glucopyranosyl-11,16-dihydroxyabieta-8,11,13-triene

Cat.No: TN6493

Cat.No: TN6776

Synonym: Cyaonoside B,川牛膝皂苷B

Target: Others

Quercetin-3-O-D-glucosyl]-(1-2)-L-rhamnoside

Cat.No: TN6734

Synonym: Quercetin 3-O-beta-D-glucosyl-(1->2)-rhamnoside,槲皮素-3-O-葡萄糖基-(1-2)-L-鼠李糖苷,槲皮素 3-O-葡萄糖基 (1→2)鼠李糖苷

Target: Others

Myricetin 3-O-beta-D-xylopyranosyl(1-2)-beta-D-glucopyranoside

Cat.No: TN4607

Target: Others

(12β)-20-(β-D-Glucopyranosyloxy)-12-hydroxydammar-24-en-3-one

Cat.No: T83579

Cat.No: T3889

Target: Prostaglandin Receptor, AMPK

2-Hydroxyanthraquinone

Cat.No: T36914

Target: Others

Hispidulin 4'-O-β-D-glucopyranoside

Cat.No: TN4216

Synonym: Hispidulin 4'-O-beta-D-glucopyranoside

Target: Others

Farrerol 7-O-β-D-glucopyranoside

Cat.No: TN4052

Synonym: Farrerol 7-O-glucoside

Target: Others

Benzyl β-D-glucopyranoside

Cat.No: TN5753

Synonym: 苄基-β-D-葡萄糖苷,Benzyl glucoside

4,6-O-Ethylidene-α-D-glucose

Cat.No: T72172

Synonym: Ethylidene-glucose

Fructo-oligosaccharide DP12/GF11

Cat.No: T19329

Synonym: 蔗果十二糖

Target: Others

Cat.No: T75567

Cat.No: TN4683

Target: ERK, IL Receptor, IκB/IKK, NOS, NF-κB, Akt, Antifection

9(S),12(S),13(S)-TriHOME

Cat.No: T37272

Cat.No: T36954

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