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76

抑制剂 & 化合物

13

天然产物

4

同位素

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Cat. No.	Product Name	Target	Signaling Pathways
T38227	Quin C1	Others	Others
	Potent and selective FPR2 agonist (EC50 = 15 nM). Induces Ca2+ mobilization in FPR2 but not FPR1-transfected mast cells. Induces neutrophil chemotaxis and degranulation in vitro. Reduces neutrophil and lymphocyte counts in bronchoalveolar lavage fluid in a mouse lung injury model. Anti-inflammatory. Zhou et al (2007) Pharmacological characterization of a novel nonpeptide antagonist for formyl peptide receptor-like 1. Mol.Pharmacol. 72 976 PMID:17652444 \|Corminboeuf et al (2014) FPR2/ALXR agonist...
T4253	Skp2 Inhibitor C1 SKPin C1	Others; E1/E2/E3 Enzyme	Others; Ubiquitination
	Skp2 Inhibitor C1 (SKPin C1)(SKPin C1)是Skp2介导p27降解的特异性抑制剂。
T71600	Benazoline oxalate salt	Others	Others
	Benazoline oxalate salt is a pharmacological active compound that inhibits casein kinase Iε (CKIε) or CKIδ phosphorylation of the PER2 protein.
T36496	Conglobatin C1 Conglobatin C1	Others	Others
	Conglobatin C1 is a bacterial metabolite that has been found inStreptomycesMST-91080 and has anticancer activity.1It is cytotoxic to NS-1 mouse myeloma cells (IC50= 1.05 μg/ml) but not NFF human fibroblasts (IC50= >100 μg/ml). 1.Lacey, H.J., Booth, T.J., Vuong, D., et al.Conglobatins B-E: Cytotoxic analogues of the C2-symmetric macrodiolide conglobatinJ. Antibiot. (Tokyo)73(11)756-765(2020)
T125452	Dracoflavan C1	Others	Others

T125395	Tetromycin C1	Others	Others
	Tetromycin C1 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125395，CAS号为 205433-82-5。
T124222	Stichloroside C1	Others	Others
	Stichloroside C1 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T124222，CAS号为 78244-73-2。
T85307	Antibody conjugate C1	Others	Others

T18560	Propargyl-C1-NHS ester 4-戊炔酸琥珀亚胺酯,4-Pentynoic Acid Succinimidyl Ester	Others	Others
	Propargyl-C1-NHS ester (4-Pentynoic Acid Succinimidyl Ester) 是一种不可切割的 ADC 接头，可用于合成抗体偶联药物。
T76702	Sutimlimab	Complement System	Immunology/Inflammation
	Sutimlimab 是一种新型靶向补体蛋白 C1 的单克隆抗体。Sutimlimab 常当作 C1 抑制剂使用，用于治疗冷凝集素病相关溶血。
T21275	Azoxystrobin HSDB 7017,ICI-A 5504,Bankit,ICIA-5504,Amistar	Antifungal	Microbiology/Virology
	Azoxystrobin (Bankit) 是一种广谱杀菌剂。 Azoxystrobin 通过阻断细胞色素 b 和 c1 之间的电子转移来诱导 ROS 产生、细胞凋亡和线粒体呼吸。
T18494	NH2-PEG6-C1-Boc H2N-PEG6-CH2COOtBu,氨基-六聚乙二醇-乙酸叔丁酯	Others; PROTAC Linker	Others; PROTAC
	NH2-PEG6-C1-Boc (H2N-PEG6-CH2COOtBu) 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T18479	NH-bis(C1-Boc) 亚氨基二乙酸二异丁酯	Others	Others
	Boc-NH-C6-Br 是一种不可切割的接头，用于抗体-药物偶联物。
T17352	Acid-C1-PEG5-Boc	Others; PROTAC Linker	Others; PROTAC
	Acid-C1-PEG5-Boc 是一种属于 PEG 类的 PROTAC linker，可用于 PROTAC 分子的合成。
T62413	SARS-CoV-2 nsp13-IN-1	Others	Others
	SARS-CoV-2 nsp13-IN-1 (compound C1) 是一种 nsp13 (非结构蛋白 13) 的有效抑制剂。SARS-CoV-2 nsp13-IN-1 只抑制nsp13 ssDNA+ATPase (IC50: 6 μM)，不抑制 ssDNA-ATPase。SARS-CoV-2 nsp13-IN-1 能够用于研究 COVID-19。
T11205	ent-Ezetimibe ent-SCH 58235,ENT-依折麦布	Others	Others
	ent-Ezetimibe (ent-SCH 58235) 是 Ezetimibe 的 RRS 型对映体。其中Ezetimibe 是一种胆固醇吸收 (cholesterol-absorption) 抑制剂，是NPC1L1抑制剂，也是有效的Nrf2激活剂。
T25313	Detoxin C1 Detoxin calpha1	Others	Others
	Detoxin C1 is a selective blasticidin S antagonist.
T17940	Estrone-N-O-C1-amido ERα ligand 1	Others	Others
	Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα). Through a linker, Estrone-N-O-C1-amido (ERα ligand 1) forms a complex with the cIAP1 ligand Bestatin, leading to the creation of SNIPER[1].
T29081	UTA1inh-C1 UTA1-inh-C1,UTA1(inh)-C1	Others	Others
	UTA1inh-C1 is a novel inhibitor of kidney urea transporter UT-A1.
T17564	Biotin-PEG2-C1-aldehyde	Others	Others
	Biotin-PEG2-C1-aldehyde is a polyethylene glycol (PEG)-based linker utilized in synthesizing proteolysis targeting chimeras (PROTACs) [1].
T17903	Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH E3 ligase Ligand-Linker Conjugates 49,Cereblon Ligand-Linker Conjugates 14	Others	Others
	Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized compound, designed as an E3 ligase ligand-linker conjugate, integrating the cereblon ligand derived from Pomalidomide and a linker employed in PROTAC technology. This compound serves to facilitate targeted protein degradation through the modulation of E3 ligase activity, enabling the selective elimination of specific proteins of interest.
TP2439	Sarasinoside C1 Sarasinoside-C1
	Sarasinoside C1 is a norlanostane-triterpenoid oligoglycoside from the Palauan marine sponge Asteropus sarasinosum.
T39177	Bromoacetamide-PEG3-C1-acid Bromoacetamide-PEG3-C1-acid	Others	Others
	Bromoacetamide-PEG3-C1-acid is a PEG-based PROTAC linker utilized for PROTAC synthesis.
T39537	Mal-amido-PEG3-C1-NHS ester Mal-amido-PEG3-C1-NHS ester	Others	Others
	Mal-amido-PEG3-C1-NHS ester is a non-cleavable, three-unit polyethylene glycol (PEG) ADC linker utilized in the development of antibody-drug conjugates (ADCs).
T17546	Biotin-C1-PEG3-C3-amine TFA	Others	Others
	Biotin-C1-PEG3-C3-amine (TFA) is a polyethylene glycol (PEG) based linker that serves as a crucial component in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T39540	Propargyl-O-C1-amido-PEG3-C2-NHS ester Propargyl-O-C1-amido-PEG3-C2-NHS ester	Others	Others
	Propargyl-O-C1-amido-PEG3-C2-NHS ester is a non-cleavable 3-unit polyethylene glycol (PEG) linker employed for the chemical synthesis of antibody-drug conjugates (ADCs).
T69393	SID-7977382	Others	Others
	SID-7977382 is a complement factor C1 inhibitor.
T11251	Ezetimibe ketone EZM-K	Nrf2; NPC1L1	Immunology/Inflammation; Membrane transporter/Ion channel
	Ezetimibe, a compound known as a Niemann-Pick C1-like1 (NPC1L1) inhibitor and a potent Nrf2 activator, effectively inhibits cholesterol absorption. Additionally, Ezetimibe ketone (EZM-K) represents a phase-I metabolite of Ezetimibe.
T37913	Picoxystrobin	Others	Others
	Picoxystrobin, a prominent primary strobilurin fungicide, is extensively utilized for efficient plant disease management. By obstructing electron transfer at the Qo center of cytochrome b and c1, picoxystrobin effectively halts mitochondrial respiration[1].
T17384	Ald-Ph-amido-PEG3-C1-Boc	Others	Others
	Ald-Ph-amido-PEG3-C1-Boc is a polyethylene glycol (PEG) linker specific to antibody-drug conjugates (ADC).
T38977	Autophagy-IN-C1 Autophagy-IN-C1	Others	Others
	Autophagy-IN-C1是一种含有尿素的金鸡纳生物碱衍生物。Autophagy-IN-C1 不仅诱导肝细胞癌（HCC）细胞凋亡，而且阻断自噬。
T16520	Ph-Bis(C1-N-(C2-NH-Boc)2)	Others	Others
	Ph-Bis(C1-N-(C2-NH-Boc)2) is a versatile alkyl chain-derived linker employed in the synthesis of PROTACs[1].
T30678	C1-resveratrol C1resveratrol,C1 resveratrol	Others	Others
	C1 resveratrol is a novel multifunctional derivative of resveratrol, which is used to treat atrial fibrillation.
T39714	Mal-PEG3-C1-NHS ester Mal-PEG3-C1-NHS ester	Others	Others
	Mal-PEG3-C1-NHS ester is a non-cleavable linker incorporating a three-unit PEG moiety, employed specifically in the synthesis of antibody-drug conjugates (ADCs).
T14477	Azido-PEG8-C1-NHS ester	Others	Others
	Azido-PEG8-C1-NHS ester is a polyethylene glycol (PEG)-based linker, specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T18627	Tos-PEG3-O-C1-CH3COO PROTAC Linker 6	Others	Others
	Tos-PEG3-O-C1-CH3COO (PROTAC Linker 6) is a PEG-based linker compound that finds utility in the synthesis of PROTACs[1].
T39534	Mal-amido-PEG3-C1-PFP ester Mal-amido-PEG3-C1-PFP ester	Others	Others
	Mal-amido-PEG3-C1-PFP ester, a non-cleavable 3 unit PEG ADC linker, finds application in the synthesis of antibody-drug conjugates (ADCs).'
T18564	Propargyl-O-C1-amido-PEG4-C2-NHS ester	Others	Others
	Propargyl-O-C1-amido-PEG4-C2-NHS ester is a non-cleavable 4-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.
T16666	NH2-PEG3-C1-Boc PROTAC Linker 5	Others	Others
	NH2-PEG3-C1-Boc, also known as PROTAC Linker 5, is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
T82007	JH-131e-153	Others	Others
	JH-131e-153, 作为一种二酰基甘油(DAG)内酯，具有激活 Munc13-1 的功能，靶向其 C1 结构域。JH-131e-153 对 Munc13-1 激活效率表现为 WT>I590≈R592A≈W588A。值得注意的是，Munc13-1 的 C1 结构域与蛋白激酶 C (PKC) 在序列和结构上具有同源性。对于 Munc13-1 和 PKC 的激活效率，JH-131e-153 的效果排序为 PKCα>Munc13-1>PKCε。该化合物通过调节 Munc13-1，对神经元过程产生影响，因此可用于神经退行性疾病的相关研究。
T16629	Propargyl-PEG4-O-C1-Boc	Others	Others
	Propargyl-PEG4-O-C1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18615	Phenol-amido-C1-PEG3-N3 PROTAC Linker 21	Others	Others
	Phenol-amido-C1-PEG3-N3, also known as PROTAC Linker 21, is a PEG-based linker utilized for synthesizing PROTACs.
T39422	(S,R,S)-AHPC-C1-NH2 (S,R,S)-AHPC-C1-NH2	Others	Others
	(S,R,S)-AHPC-C1-NH2 is a synthesized conjugate for E3 ligase, combining the VHL ligand based on (S,R,S)-AHPC with a linker utilized in PROTAC technology.
T18530	PDP-C1-Ph-Val-Cit	Others	Others
	PDP-C1-Ph-Val-Cit is a cleavable ADC linker used for antibody-drug conjugates (ADCs).
T39215	Thalidomide-O-amido-C3-PEG3-C1-NH2 Thalidomide-O-amido-C3-PEG3-C1-NH2	Others	Others
	Thalidomide-O-amido-C3-PEG3-C1-NH2 is a synthesized conjugate compound that serves as an E3 ligase ligand-linker. It features a cereblon ligand based on Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology.
T18637	Boc-C1-PEG2-C4-Cl PROTAC Linker 1	Others	Others
	Boc-C1-PEG2-C4-Cl (PROTAC Linker 1) is a PEG-based compound utilized for the synthesis of PROTACs. This chemical compound serves as a linker in the development of PROTACs[1].
T11003	Desfluoro-ezetimibe	Others	Others
	Desfluoro-ezetimibe is the defluorinated impurity of ezetimibe. Ezetimibe is an effective, metabolically stable cholesterol absorption inhibitor. Ezetimibe is a Niemann-Pick C1-like1 (NPC1L1) inhibitor and an effective Nrf2 activator.
T14393	Azide-PEG3-C1-Ala	Others	Others
	Azide-PEG3-C1-Ala is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T18492	NH2-PEG5-C1-Boc	Others	Others
	NH2-PEG5-C1-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
T14850	C-NH-Boc-C-Bis-(C1-PEG1-PFP)	Others	Others
	C-NH-Boc-C-Bis-(C1-PEG1-PFP) is a polyethylene glycol (PEG)-derived PROTAC linker, which finds application in the synthesis of PROTACs[1].

化合物

Cat.No: T38227

Target: Others

Skp2 Inhibitor C1

Cat.No: T4253

Synonym: SKPin C1

Target: Others, E1/E2/E3 Enzyme

Benazoline oxalate salt

Cat.No: T71600

Target: Others

Cat.No: T36496

Synonym: Conglobatin C1

Target: Others

Cat.No: T125452

Target: Others

Cat.No: T125395

Target: Others

Stichloroside C1

Cat.No: T124222

Target: Others

Antibody conjugate C1

Cat.No: T85307

Target: Others

Propargyl-C1-NHS ester

Cat.No: T18560

Synonym: 4-戊炔酸琥珀亚胺酯,4-Pentynoic Acid Succinimidyl Ester

Target: Others

Cat.No: T76702

Target: Complement System

Cat.No: T21275

Synonym: HSDB 7017,ICI-A 5504,Bankit,ICIA-5504,Amistar

Target: Antifungal

NH2-PEG6-C1-Boc

Cat.No: T18494

Synonym: H2N-PEG6-CH2COOtBu,氨基-六聚乙二醇-乙酸叔丁酯

Target: Others, PROTAC Linker

Cat.No: T18479

Synonym: 亚氨基二乙酸二异丁酯

Target: Others

Acid-C1-PEG5-Boc

Cat.No: T17352

Target: Others, PROTAC Linker

SARS-CoV-2 nsp13-IN-1

Cat.No: T62413

Target: Others

Cat.No: T11205

Synonym: ent-SCH 58235,ENT-依折麦布

Target: Others

Cat.No: T25313

Synonym: Detoxin calpha1

Target: Others

Estrone-N-O-C1-amido

Cat.No: T17940

Synonym: ERα ligand 1

Target: Others

Cat.No: T29081

Synonym: UTA1-inh-C1,UTA1(inh)-C1

Target: Others

Biotin-PEG2-C1-aldehyde

Cat.No: T17564

Target: Others

Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH

Cat.No: T17903

Synonym: E3 ligase Ligand-Linker Conjugates 49,Cereblon Ligand-Linker Conjugates 14

Target: Others

Sarasinoside C1

Cat.No: TP2439

Synonym: Sarasinoside-C1

Bromoacetamide-PEG3-C1-acid

Cat.No: T39177

Synonym: Bromoacetamide-PEG3-C1-acid

Target: Others

Mal-amido-PEG3-C1-NHS ester

Cat.No: T39537

Synonym: Mal-amido-PEG3-C1-NHS ester

Target: Others

Biotin-C1-PEG3-C3-amine TFA

Cat.No: T17546

Target: Others

Propargyl-O-C1-amido-PEG3-C2-NHS ester

Cat.No: T39540

Synonym: Propargyl-O-C1-amido-PEG3-C2-NHS ester

Target: Others

Cat.No: T69393

Target: Others

Ezetimibe ketone

Cat.No: T11251

Synonym: EZM-K

Target: Nrf2, NPC1L1

Cat.No: T37913

Target: Others

Ald-Ph-amido-PEG3-C1-Boc

Cat.No: T17384

Target: Others

Autophagy-IN-C1

Cat.No: T38977

Synonym: Autophagy-IN-C1

Target: Others

Ph-Bis(C1-N-(C2-NH-Boc)2)

Cat.No: T16520

Target: Others

Cat.No: T30678

Synonym: C1resveratrol,C1 resveratrol

Target: Others

Mal-PEG3-C1-NHS ester

Cat.No: T39714

Synonym: Mal-PEG3-C1-NHS ester

Target: Others

Azido-PEG8-C1-NHS ester

Cat.No: T14477

Target: Others

Tos-PEG3-O-C1-CH3COO

Cat.No: T18627

Synonym: PROTAC Linker 6

Target: Others

Mal-amido-PEG3-C1-PFP ester

Cat.No: T39534

Synonym: Mal-amido-PEG3-C1-PFP ester

Target: Others

Propargyl-O-C1-amido-PEG4-C2-NHS ester

Cat.No: T18564

Target: Others

NH2-PEG3-C1-Boc

Cat.No: T16666

Synonym: PROTAC Linker 5

Target: Others

Cat.No: T82007

Target: Others

Propargyl-PEG4-O-C1-Boc

Cat.No: T16629

Target: Others

Phenol-amido-C1-PEG3-N3

Cat.No: T18615

Synonym: PROTAC Linker 21

Target: Others

(S,R,S)-AHPC-C1-NH2

Cat.No: T39422

Synonym: (S,R,S)-AHPC-C1-NH2

Target: Others

PDP-C1-Ph-Val-Cit

Cat.No: T18530

Target: Others

Thalidomide-O-amido-C3-PEG3-C1-NH2

Cat.No: T39215

Synonym: Thalidomide-O-amido-C3-PEG3-C1-NH2

Target: Others

Boc-C1-PEG2-C4-Cl

Cat.No: T18637

Synonym: PROTAC Linker 1

Target: Others

Desfluoro-ezetimibe

Cat.No: T11003

Target: Others

Azide-PEG3-C1-Ala

Cat.No: T14393

Target: Others

NH2-PEG5-C1-Boc

Cat.No: T18492

Target: Others

C-NH-Boc-C-Bis-(C1-PEG1-PFP)

Cat.No: T14850

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T2777	Ginsenoside Rg1 Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,人参皂苷Rg1,Panaxoside A,人参皂苷 Rg1,Ginsenoside A2	Apoptosis; Beta Amyloid; NF-κB	Apoptosis; Neuroscience; NF-κB
	Ginsenoside Rg1 (Panaxoside Rg1) 是人参的主要活性成分之一，可减少NF-κB 核易位。它改善认知功能受损，通过降低大脑Aβ水平来发挥作用。
TN2103	PROCYANIDIN C1 原花青素 C1,原花青素C1	Apoptosis	Apoptosis
	Procyanidin C1 是一种天然多酚，可造成 DNA 损伤，细胞周期停滞，诱导凋亡。它降低癌细胞中 Bcl-2 的蛋白水平，增强 BAX，caspase 3 和 9 的表达。
TN7077	Sinocrassoside C1	Others	Others
	Sinocrassoside C1 是中国景天（景天科）全植物的甲醇提取物。
T22598	Bafilomycin C1 巴菲霉素C1	Others	Others
	vacuolar H+-ATPases (V-ATPases) inhibitor
TN1660	Ganoderic acid C1 灵芝酸 C1,灵芝酸C1	IL Receptor; TNF; NF-κB; MAPK; COX; HIV Protease; DNA/RNA Synthesis	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Immunology/Inflammation; MAPK; Microbiology/Virology; Neuroscience; NF-κB; Proteases/Proteasome
	Ganoderic acid C1 是分离自 G. lucidum 中的天然产物，能够抑制小鼠巨噬细胞TNF-α 的生成。
T82713	Ciwujianoside C1
	Ciwujianoside C1, 一种从Acanthopanax senticosus叶中分离得到的皂苷，具有抑制体外胰腺脂肪酶活性的功能。
T19503	Papain	Others; Cysteine Protease	Others; Proteases/Proteasome
	Papain 是一种半胱氨酸蛋白酶，是肽酶 C1 家族中一员，在食品、医药、化妆品、纺织等具有广泛的应用。
T0437	Inosine INO 495,NSC 20262,肌苷	ROS; Endogenous Metabolite; Adenosine Receptor	GPCR/G Protein; Immunology/Inflammation; Metabolism; Neuroscience
	Inosine (NSC-20262) 是由腺苷分解代谢产生的一种内源性嘌呤核苷，是腺苷受体A1R 和A2AR 的激动剂，具有抗炎免疫调节，抗伤害和神经保护作用。
T4758	2'-Deoxycytidine Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物	Endogenous Metabolite	Metabolism
	2'-Deoxycytidine 是由胞嘧啶和脱氧核糖组成的DNA的主要核苷之一，抑制溴脱氧尿苷 (Brdu) 的生物效应。核苷仅由与嘌呤或嘧啶碱相连的戊糖组成，没有磷酸基团。当N1与脱氧核糖的C1连接时，由胞嘧啶和脱氧核糖形成脱氧核苷和核苷酸；脱氧胞苷单磷酸(dCMP)，脱氧胞苷二磷酸(dCDP)，脱氧胞苷三磷酸(dCTP)。CTP是RNA(核糖核酸)中胞苷的来源，脱氧胞苷三磷酸(dCTP)是DNA(脱氧核糖核酸)中脱氧胞苷的来源。
T8047	Menthyl acetate 乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-Menthyl acetate,L-Menthyl acetate	Others	Others
	Menthyl acetate 是一种可有效增强 5-氨基乙酰丙酸 (ALA) 皮肤渗透的 L-薄荷醇衍生物。
TN6583	Cistantubuloside C1
	Cistantubuloside C1 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN6583，CAS号为 620632-36-2。
T36990	Moenomycin Complex	Others	Others
	Moenomycin complex is a mixture of moenomycins A, A12, C1, C3 and C4, which are antibiotics isolated from several strains of Streptomyces that directly inhibit bacterial peptidoglycan glycosyltransferases. [1] The minimal inhibitory concentration of moenomycin A against various Gram-positive bacteria ranges from 1-100 nM.[1]
T14831	Bryostatin 1	HIV Protease; PKC	Chromatin/Epigenetic; Cytoskeletal Signaling; Microbiology/Virology; Proteases/Proteasome
	Bryostatin 1 is a natural macrolide isolated from the bryozoan Bugula neritina and is a CNS)permeable PKC modulator. Bryostatin 1 binds to the isolated C1 domain of Munc13-1 and the full-length Munc13-1 protein (Kis: 8.07 nM and 0.45 nM).

天然产物

Ginsenoside Rg1

Cat.No: T2777

Synonym: Sanchinoside C1,Panaxoside Rg1,Sanchinoside Rg1,人参皂苷Rg1,Panaxoside A,人参皂苷 Rg1,Ginsenoside A2

Target: Apoptosis, Beta Amyloid, NF-κB

Cat.No: TN2103

Synonym: 原花青素 C1,原花青素C1

Target: Apoptosis

Sinocrassoside C1

Cat.No: TN7077

Target: Others

Cat.No: T22598

Synonym: 巴菲霉素C1

Target: Others

Ganoderic acid C1

Cat.No: TN1660

Synonym: 灵芝酸 C1,灵芝酸C1

Target: IL Receptor, TNF, NF-κB, MAPK, COX, HIV Protease, DNA/RNA Synthesis

Ciwujianoside C1

Cat.No: T82713

Cat.No: T19503

Target: Others, Cysteine Protease

Cat.No: T0437

Synonym: INO 495,NSC 20262,肌苷

Target: ROS, Endogenous Metabolite, Adenosine Receptor

2'-Deoxycytidine

Cat.No: T4758

Synonym: Cytosine deoxyribonucleoside,2'-Deoxycytidine monohydrate,2(1H)-Pyrimidinone,Cytosine deoxyriboside,Deoxyribose cytidine,Deoxycytidine,2'-脱氧胞嘧啶核苷一水合物

Target: Endogenous Metabolite

Menthyl acetate

Cat.No: T8047

Synonym: 乙酸-L-孟酯,(1R)-(-)-Menthyl acetate,(-)-Menthyl acetate,L-Menthyl acetate

Target: Others

Cistantubuloside C1

Cat.No: TN6583

Moenomycin Complex

Cat.No: T36990

Target: Others

Cat.No: T14831

Target: HIV Protease, PKC

Cat. No.	Product Name	Target	Signaling Pathways
T35789	Palmitic acid-1-13C
	Palmitic acid-13C is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a 16-carbon saturated fatty acid. It comprises approximately 25% of human total plasma lipids.1 It increases protein levels of COX-2 in RAW 264.7 cells when used at a concentration of 75 μM.2 Palmitic acid is involved in the acylation of proteins to anchor membrane-bound proteins to the lipid bilayer.2,3,4,5,6 \|1. Santos, M.J., López-Jurado, M., Llopis, J., et a...
T35790	Palmitic acid-1,2,3,4-13C4 Palmitic Acid-13C (C1, C2, C3, and C4 labeled)
	Palmitic acid-13C (C1, C2, C3, and C4 labeled) is intended for use as an internal standard for the quantification of palmitic acid by GC- or LC-MS. Palmitic acid is a common 16-carbon saturated fat that represents 10-20% of human dietary fat intake and comprises approximately 25 and 65% of human total plasma lipids and saturated fatty acids, respectively.1,2Acylation of palmitic acid to proteins facilitates anchoring of membrane-bound proteins to the lipid bilayer and trafficking of intracellula...
T11250	Ezetimibe-d4 SCH 58235 D4	Others	Others
	Ezetimibe D4, a deuterium-labeled variant of Ezetimibe, functions as an inhibitor of Niemann-Pick C1-like1 (NPC1L1) and is recognized for its potent activation of Nrf2.
T37044	1,2-Dioleoyl-rac-glycerol-13C3 1,2-Dioleoyl-rac-glycerol-13C3
	1,2-Dioleoyl-rac-glycerol-13C3 is intended for use as an internal standard for the quantification of 1,2-dioleoyl-rac-glycerol by GC- or LC-MS. 1,2-dioleoyl-rac-glycerol is a diacylglycerol that contains oleic acid at the sn-1 and sn-2 positions. It effectively binds the C1 domain to activate conventional protein kinase C forms and serves as a substrate for diacylglycerol kinases and multisubstrate lipid kinase.1,2,3 \|1. Yamaguchi, Y., Shirai, Y., Matsubara, T., et al. Phosphorylation and up-reg...

同位素

Palmitic acid-1-13C

Cat.No: T35789

Palmitic acid-1,2,3,4-13C4

Cat.No: T35790

Synonym: Palmitic Acid-13C (C1, C2, C3, and C4 labeled)

Cat.No: T11250

Synonym: SCH 58235 D4

Target: Others

1,2-Dioleoyl-rac-glycerol-13C3

Cat.No: T37044

Synonym: 1,2-Dioleoyl-rac-glycerol-13C3

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