7
67
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T80583 |
Anti-Mouse 4-1BB Antibody (3H3)
|
||
Anti-Mouse4-1BBAntibody为针对小鼠4-1BB的IgG2a类抗体抑制剂,源自宿主Rat。 | |||
T76705 |
Utomilumab
PF 05082566,PF-2566 |
TNF | Apoptosis |
Utomilumab (PF 05082566) 是一种人源化靶向T 细胞共刺激受体4-1BB/CD137的 IgG2 抗体,也是一种 4-1BB/CD137 激动剂。Utomilumab 具有抗肿瘤活性,可用于研究晚期恶性肿瘤患者。 | |||
T80590 |
Cinrebafusp alfa
PRS 343 |
EGFR | Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors |
Cinrebafusp alfa (PRS 343) 是高亲和力 CD137/HER2 双特异性抗体融合蛋白,能结合重组人 HER2 (Kd=0.3 nM) 及人单体 CD137 (4-1BB; Kd=5 nM)。通过 HER2 导向的 4-1BB 聚集激活,Cinrebafusp alfa 促进 T 细胞的共刺激作用,增强 T细胞受体介导的活性,从而有效打击 HER2+ 实体瘤。 | |||
T76897 | Acasunlimab | ||
Acasunlimab (GEN1046) 是一种双特异性抗体 (bsAb),靶向PD-L1和4-1BB。Acasunlimab 通过有条件的4-1BB 刺激增强 T 细胞和 NK 细胞功能,同时构成性地阻断PD-1/PD-L1抑制轴。Acasunlimab 可用于癌症的研究。 | |||
T80578 |
Evunzekibart
ATOR-1017 |
||
Evunzekibart (ATOR-1017)是一种以Fc-γ受体为条件的4-1BB激动剂,属于IgG4亚型抗体。该化合物既可以作为单药疗法,也可与抗PD1治疗相结合,以发挥其抗肿瘤效果。 | |||
T76984 | Tecaginlimab | ||
Tecaginlimab (BNT-312) 是一种 Fc 惰性双特异性抗体,用于CD40和4-1BB 的双重靶向和条件刺激。Tecaginlimab 可以增强肿瘤特异性免疫的启动和再激活。 | |||
T82466 |
Englumafusp alfa
RG6076,CD19-4-1BBL,RO7227166 |
||
Englumafusp alfa (CD19-4-1BBL; RO7227166)是一款由CD19特异性抗体域与人41BBL的三聚体胞外域结合构成的融合蛋白。该化合物能够促进T细胞与NK细胞表面CD19特异性4-1BB的交联作用。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00033 |
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc)
CD137L,4-1BB-L,tumor nec... |
Human | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.9 kDa and the accession number is A0A0U5J8I0. | |||
TMPY-01743 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His)
4-1BB,tumor necrosis factor recep... |
Human | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.8 kDa and the accession number is Q07011. | |||
TMPY-05376 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc)
4-1BB,tumor necrosis factor recep... |
Human | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is Q07011. | |||
TMPJ-00139 |
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His)
4-1BBL,Tumor necrosis factor liga... |
Human | E. coli |
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 16-20 KDa and the accession number is P41273. | |||
TMPY-05594 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CDw137,CD137,4-1BB |
Human | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with hFc and Avi tag. The predicted molecular weight is 45.8 kDa and the accession number is Q07011. | |||
TMPY-05767 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His)
tumor necrosis factor receptor superfamily, member 9,AA4... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.00 kDa and the accession number is P20334. | |||
TMPJ-00141 |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc)
4-1BB ligand receptor,CD1 |
Cynomolgus | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60 KDa and the accession number is A9YYE7. | |||
TMPJ-00142 |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His)
CDw137,ILA,4-1BB ligand ... |
Cynomolgus | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 26-35 KDa and the accession number is A9YYE7. | |||
TMPY-06831 |
4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (hFc)
4-1BB-L,Ly63l,4-1 |
Mouse | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.41 kDa and the accession number is NP_033430.1. | |||
TMPJ-00140 |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
CD137,CDw137,4-1BB |
Cynomolgus | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Pro... | |||
TMPK-00147 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi)
T cell antigen ILA,ILA,4-1BB liga... |
Human | HEK293 Cells |
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & Avi) is expressed in HEK293 mammalian cells with... | |||
TMPY-00959 |
4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His)
4-1BBL,Cd137l,tumor necr... |
Mouse | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25 kDa and the accession number is P41274. | |||
TMPY-05819 |
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (Avi & Fc), Biotinylated
4-1BBL,4-1B... |
Human | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (Avi & Fc), Biotinylated is expressed in HEK293 mammalian cells with AVI and Fc tag. The predicted molecular weight is 47.98 kDa and the accession number is A0A0U5J8I0. | |||
TMPJ-00144 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (hFc & His)
CD137,4-1BB ligand recep... |
Human | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Pro... | |||
TMPJ-00138 |
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag)
Tumor necrosis factor ligand superfamily member 9,4... |
Human | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Human, Recombinant (His & Flag) is expressed in HEK293 mammalian cells with N-6xHis-Flag tag. The predicted molecular weight is 30 KDa and the accession number is P41273. | |||
TMPJ-00143 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, His & Avi), Biotinylated
ILA,4-1BB ligand receptor,T-cell ... |
Human | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is an inducible T cell surface protein belonging to the TNF receptor superfamily. It is a single-pass type I membrane protein which contains 4 TNFR-Cys repeats. The human and mouse proteins share 60% amino acid sequence identity. It is absent from naive T cells, but upregulated and continually expressed following T cell activation. It is a receptor for TNFSF9/4-1BBL, and possibly active during T cell activation. 4-1BB/CD137/TNFRSF9 Pro... | |||
TMPY-06528 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His)
tumor necrosis factor receptor superfamily, member 9,4 |
Human | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (soluble CD137, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.70 kDa and the accession number is Q07011. | |||
TMPY-06382 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated
tumor necrosis factor receptor superfamily, member 9,4 |
Human | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 20.54 kDa and the accession number is NP_001552.2. | |||
TMPK-00148 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, hFc & Avi), Biotinylated
TNFRSF9,FLJ43501,4-1... |
Human | HEK293 Cells |
4-1BB, is also known as CD137, is a type 2 transmembrane glycoprotein receptor belonging to the TNF superfamily.CD137 can be expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, CD137 expression is found on dendritic cells, B cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. 4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (aa 24-186, hFc & Avi), Biotinylated is expressed in HE... | |||
TMPY-05105 |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His), Biotinylated
CDw137,ILA,4-1BB,CD1... |
Human | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is Q07011. | |||
TMPY-06279 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated
Cd137,tumor necrosis factor receptor superfamily, m... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 19.00 kDa and the accession number is P20334. | |||
TMPY-06329 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated
CDw137,AI325004,Cd137,Ly63,tumor ... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-211, His&AVI), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.32 kDa and the accession number is NP_001070976.1. | |||
TMPY-05504 |
4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated
tumor necrosis factor receptor superfamily, member 9 |
Rhesus | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Rhesus, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is XP_005544945.1&NP_001253057.1. | |||
TMPY-02992 |
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (hFc)
tumor necrosis factor (ligand) superfamily, member 9 |
Rat | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.9 kDa and the accession number is Q80WE6. | |||
TMPY-02993 |
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (His)
tumor necrosis factor (ligand) superfamily, member 9 |
Rat | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24.8 kDa and the accession number is Q80WE6. | |||
TMPY-00230 |
4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (hFc)
tumor necrosis factor receptor superfamily, member 9 |
Canine | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43.9 kDa and the accession number is XP_850336.1. | |||
TMPY-03773 |
4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (His)
tumor necrosis factor receptor superfamily, member 9 |
Canine | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.4 kDa and the accession number is XP_850336.1. | |||
TMPY-05173 |
4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc)
tumor necrosis factor (ligand) superfamily, member 9 |
Cynomolgus | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is XP_015296398.1. | |||
TMPJ-00145 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (hFc)
Tumor necrosis factor receptor superfamily member 9,Tnfrsf9,... |
Mouse | HEK293 Cells |
Tumor necrosis factor receptor superfamily member 9(TNFRSF9) is a member of the tumor necrosis factor (TNF) receptor family. It can be induced by lymphocyte activation (ILA) and is expressed by activated T cells, but to a larger extent on CD8 than on CD4 T cells. In addition, TNFRSF9 expression is found on dendritic cells, follicular dendritic cells, natural killer cells, granulocytes and cells of blood vessel walls at sites of inflammation. As receptor for TNFSF9/4-1BBL, it can activate T cells... | |||
TMPY-05506 |
4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc), Biotinylated
tumor necrosis factor (ligand) superfamily, member 9 |
Cynomolgus | HEK293 Cells |
4-1BB Ligand/TNFSF9 Protein, Cynomolgus, Recombinant (hFc), Biotinylated is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47.8 kDa and the accession number is XP_015296398.1. | |||
TMPY-04719 |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
tumor necrosis factor receptor superfamily, member 9 |
Cynomolgus,Rhesus | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 44 kDa and the accession number is XP_005544945.1&NP_001253057.1. | |||
TMPY-04720 |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (His)
tumor necrosis factor receptor superfamily, member 9 |
Cynomolgus,Rhesus | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Cynomolgus, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.7 kDa and the accession number is XP_005544945.1&NP_001253057.1. | |||
TMPY-04995 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, rFc)
A930040I11Rik,tumor necrosis fact... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, rFc) is expressed in HEK293 mammalian cells with rFc tag. The predicted molecular weight is 46.1 kDa. | |||
TMPY-02330 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, hFc)
Cd137,A930040I11Rik,tumo... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 47 kDa and the accession number is Q8R037. | |||
TMPY-05031 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, His)
CDw137,4-1BB,AI32500... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (soluble form, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q8R037. | |||
TMPY-06794 |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-187, His & Avi), Biotinylated
tumor necrosis factor receptor superfamily, member 9,AA4... |
Mouse | HEK293 Cells |
4-1BB/CD137/TNFRSF9 Protein, Mouse, Recombinant (aa 1-187, His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 20.81 kDa and the accession number is NP_001070977.1. | |||
TMPY-00749 |
FGF-2 Protein, Human, Recombinant
fibroblast growth factor 2 (basic),FGF-2,FGFB,HBGF-2,BFGF |
Human | E. coli |
FGF-2 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.5 kDa and the accession number is P09038-4. | |||
TMPJ-00864 |
VEGF165 Protein, Human, Recombinant
Vascular Endothelial Growth Factor Isoform 165,血管内皮... |
Human | HEK293 Cells |
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimul... | |||
TMPK-00823 |
VEGF165 Protein, Human, Recombinant (His & Avi)
血管内皮生长因子,RP1-261G23.1,MVCD1 |
Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4. | |||
TMPY-04911 |
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated
vascular endothelial growth factor A,血管内皮生长因子 |
Human,Cynomolgus | HEK293 Cells |
VEGF165 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 23.1 kDa and the accession number is P15692-4. | |||
TMPY-02893 |
NT5C3A/NT5C3 Protein, Human, Recombinant
P5N1,P5N-1,hUMP1,NT5C3,cN-III,PSN... |
Human | E. coli |
NT5C3A (5'-Nucleotidase, Cytosolic IIIA) is a Protein Coding gene. This gene encodes a member of the 5'-nucleotidase family of enzymes that catalyze the dephosphorylation of nucleoside 5'-monophosphates. The encoded protein is the type 1 isozyme of pyrimidine 5' nucleotidase and catalyzes the dephosphorylation of pyrimidine 5' monophosphates. NT5C3A expression required both an intronic IFN-stimulated response element and the IFN-stimulated transcription factor IRF1. Overexpression of NT5C3A, but... | |||
TMPK-00424 |
CD45 Protein, Human, Recombinant (His & Avi), Biotinylated
LCA,LY5,EC 3.1.3.48,CD45,L-CA,T20... |
Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi... | |||
TMPK-00822 |
VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled
RP1-261G23.1,VEGFA,MGC70609,VEGF,... |
Human | HEK293 Cells |
Vascular endothelial growth factor (VEGF or VEGF-A), also known as vascular permeability factor (VPF), is a potent mediator of both angiogenesis and vasculogenesis in the fetus and adult. VEGF165 appears to be the most abundant and potent isoform, followed by VEGF121 and VEGF189. VEGF165 Protein, Human, Recombinant (His & Avi), FITC-Labeled is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 22.2 kDa and the accession number is P15692-4. | |||
TMPJ-00782 |
Amyloid Precursor Protein, Human, Recombinant (hFc)
Amyloid Precursor,Amyloid Precursor Protein 695,APP695 |
Human | HEK293 Cells |
Amyloid precursor protein (APP) is a type I membrane protein with several isoforms due to alternative splicing, performs physiological functions on the surface of neurons relevant to neurite growth, neuronal adhesion and axonogenesis. Of the three major splice isoforms of APP (APP695, APP751, and APP770) APP695 is the predominant neuronal form from which Amyloid beta peptide and transcriptionally-active cleaved intracellular domain of APP (AICD) are preferentially generated by selective process... | |||
TMPY-04754 |
CASK Protein, Human, Recombinant
CMG,LIN2,MRXSNA,CAMGUK,calcium/calmodulin-dependent serine p... |
Human | Baculovirus Insect Cells |
CASK Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 102.1 kDa and the accession number is O14936-4. | |||
TMPY-00225 |
CLEC9A Protein, Mouse, Recombinant (hFc)
C-type lectin domain family 9, member A,9830005G06Rik,DNGR-<... |
Mouse | HEK293 Cells |
CLEC9A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 52.1 kDa and the accession number is Q8BRU4-4. | |||
TMPY-01117 |
MRAP Protein, Human, Recombinant (hFc)
FALP,FGD2,melanocortin 2 receptor accessory protein,GCCD2,B2... |
Human | HEK293 Cells |
MRAP (Melanocortin 2 Receptor Accessory Protein) is a Protein Coding gene. This gene encodes a melanocortin receptor-interacting protein. It belongs to the MRAP family. MRAP, which contains a single transmembrane domain, has a unique structure, an antiparallel homodimer. MRAP is a single transmembrane domain accessory protein and a critical component of the hypothamo pituitary-adrenal axis. MRAP is highly expressed in the adrenal gland and is essential for adrenocorticotropin hormone (ACTH) rece... | |||
TMPJ-00233 |
CD200R1/CRTR2 Protein, Human, Recombinant (His)
Cell Surface Glycoprotein CD200 Receptor 1,OX2R,MOX... |
Human | HEK293 Cells |
Cell surface glycoprotein CD200 Receptor 1 (CD200R1) is the receptor for the CD200 (OX-2) membrane glycoprotein. CD200R1 contains one C2- type Ig-like domain and one V-type Ig-like domain within its extracellular domain and a PTB-signaling motif in cytoplasmic domain. CD200R1 and CD200 associate via their respective N-terminal Ig-like domains. CD200R1 is restricted primarily to mast cells, basophils, macrophages, and dendritic cells. It propagates inhibitory signals despite its lacking a cytopla... | |||
TMPK-00423 |
CD45 Protein, Human, Recombinant (His & Avi)
CD45R,LY5,EC 3.1.3.48,B220,CD... |
Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (His & Avi... | |||
TMPJ-01333 |
TEM8/ANTXR1 Protein, Human, Recombinant (His)
ATR,ANTXR1,TEM8,Tumor Endothelial Marker 8,Anthrax ... |
Human | HEK293 Cells |
Anthrax Toxin Receptor 1 (ANTXR1) is a single-pass type I membrane protein that belongs to the ATR family. ANTXR1 contains one VWFA domain and binds PA through the VWA domain. ANTXR1 is highly expressed in tumor endothelial cells. ANTXR1 plays a role in cell attachment and migration. ANTXR1 interacts with extracellular matrix proteins and the actin cytoskeleton, it mediates adhesion of cells to type 1 collagen and gelatin, reorganization of the actin cytoskeleton and promotes cell spreading. It ... | |||
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