在实体肿瘤方面CAR-T取得了一定的研究进展,包括食管癌、胃癌、肝癌、结直肠癌、胰腺癌、胆管癌等。与血液瘤相比,实体瘤类型繁多、致病机制多样,靶标选择难度大,在研项目的靶点较为分散。整体来看,Mesothelin、HER2、EGFR、GPC3、GD2、CD276、MUC1、Claudin 18.2(CLDN18.2)等是常见靶点。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-05106 | Glypican 3/GPC3 Protein, Human, Recombinant (His), Biotinylated
Glypican 3/GPC3 Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 |
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed... | |||
TMPY-05117 | EpCAM/TROP1 Protein, Human, Recombinant (hFc), Biotinylated
EpCAM/TROP1 Protein, Human, Recombinant (hFc), Biotinylated
|
Human | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF... | |||
TMPY-05152 | TROP-2 Protein, Rat, Recombinant (His)
TROP-2 Protein, Rat, Recombinant (His)
|
Rat | HEK293 |
TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide va... | |||
TMPY-05211 | EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)
EGFR Protein, Human, Recombinant (Isoform vIII, aa 1-375, His)
|
Human | Baculovirus-Insect Cells |
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in... | |||
TMPY-05258 | EGFR Protein, Human, Recombinant (Isoform Viii, hFc)
EGFR Protein, Human, Recombinant (Isoform Viii, hFc)
|
Human | Baculovirus-Insect Cells |
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in... | |||
TMPY-05279 | B7-H3 Protein, Human, Recombinant (hFc), Biotinylated
B7-H3 Protein, Human, Recombinant (hFc), Biotinylated
|
Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor... | |||
TMPY-05315 | HER2/ERBB2 Protein, Human, Recombinant (His & Avi), Biotinylated
HER2/ERBB2 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... | |||
TMPY-05368 | HER2/ERBB2 Protein, Human, Recombinant (hFc), Biotinylated
HER2/ERBB2 Protein, Human, Recombinant (hFc), Biotinylated
|
Human | HEK293 |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... | |||
TMPY-05382 | VEGFR2/KDR Protein, Cynomolgus, Recombinant (His)
VEGFR2/KDR Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-05433 | B7-H3 Protein, Mouse, Recombinant (hFc)
B7-H3 Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor... | |||
TMPY-05441 | HGFR/c-Met Protein, Human, Recombinant (hFc)
HGFR/c-Met Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is over... | |||
TMPY-05583 | CD70 Protein, Human, Recombinant (hFc & Avi), Biotinylated
CD70 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept... | |||
TMPY-05601 | EpCAM/TROP1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
EpCAM/TROP1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF... | |||
TMPY-05603 | ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated
ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
ROR1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 with His and AVI tag. The predicted molecular weight is 45.2 kDa. Accession num... | |||
TMPY-05607 | HGFR/c-Met Protein, Human, Recombinant (His & Avi), Biotinylated
HGFR/c-Met Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is over... | |||
TMPY-05610 | VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-05612 | EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated
EGFR Protein, Human, Recombinant (aa 1-645, His & Avi), Biotinylated
|
Human | HEK293 |
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in... | |||
TMPY-05637 | EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated
EGFR Protein, Human, Recombinant (aa 1-378, His & Avi), Biotinylated
|
Human | Baculovirus-Insect Cells |
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in... | |||
TMPY-05639 | ROR2 Protein, Human, Recombinant (His & Avi), Biotinylated
ROR2 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
ROR2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 with His and AVI tag. The predicted molecular weight is 44.6 kDa. Accession num... | |||
TMPY-05657 | VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (hFc), Biotinylated
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... |