在实体肿瘤方面CAR-T取得了一定的研究进展,包括食管癌、胃癌、肝癌、结直肠癌、胰腺癌、胆管癌等。与血液瘤相比,实体瘤类型繁多、致病机制多样,靶标选择难度大,在研项目的靶点较为分散。整体来看,Mesothelin、HER2、EGFR、GPC3、GD2、CD276、MUC1、Claudin 18.2(CLDN18.2)等是常见靶点。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPK-00578 | ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated
ROR2 Protein, Human, Recombinant (aa 34-403, His & Avi), Biotinylated
|
Human | HEK293 Cells |
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl... | |||
TMPK-00579 | ROR2 Protein, Human, Recombinant (hFc)
ROR2 Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl... | |||
TMPK-00645 | VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)
VEGFR2/KDR Protein, Rhesus macaque, Recombinant (His)
|
Rhesus | HEK293 Cells |
Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, t... | |||
TMPK-00666 | CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)
CD27 Ligand/CD70 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 Cells |
CD70, also named CD27 ligand (CD27L), is a type II transmembrane glycoprotein belonging to the TNF superfamily (TNFSF) and has been designated TNFSF7. CD70 is a... | |||
TMPK-00679 | EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant
EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant
|
Cynomolgus,Rhesus | HEK293 Cells |
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 2... | |||
TMPK-00680 | EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
EpCAM/TROP1 Protein, Cynomolgus/Rhesus macaque, Recombinant (His)
|
Cynomolgus,Rhesus | HEK293 Cells |
Epithelial Cellular Adhesion Molecule (EpCAM), also known as KS1/4, gp40, GA733-2, 17-1A, and TROP‑1, is a 40 kDa transmembrane glycoprotein that consists of a 2... | |||
TMPK-00689 | EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
EGFRVIII Protein, Human, Recombinant (His & Avi), PE-Labeled
|
Human | HEK293 Cells |
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with E... | |||
TMPK-00690 | EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled
EGFRVIII Protein, Human, Recombinant (His & Avi), FITC-Labeled
|
Human | HEK293 Cells |
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with E... | |||
TMPK-00691 | EGFRVIII Protein, Human, Recombinant (His & Avi)
EGFRVIII Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with E... | |||
TMPK-00692 | EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated
EGFRVIII Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 Cells |
The epidermal growth factor receptor (EGFR) is overexpressed in a variety of human epithelial tumors, often as a consequence of gene amplification. Tumors with E... | |||
TMPK-00828 | Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
Mucin-1/MUC1 Isoform Y Protein, Human, Recombinant (hFc)
|
Human | HEK293 Cells |
MUC1, the transmembrane glycoprotein Mucin 1, is usually found to be overexpressed in a variety of epithelial cancers playing an important role in disease progre... | |||
TMPK-00902 | EGFR Protein, Rhesus macaque, Recombinant (His)
EGFR Protein, Rhesus macaque, Recombinant (His)
|
Rhesus | HEK293 Cells |
EGFR Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.8 kDa and the accessi... | |||
TMPK-01016 | B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
|
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet ... | |||
TMPK-01017 | B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)
B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)
|
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet ... | |||
TMPK-01018 | B7-H3 Protein, Human, Recombinant (aa 29-245, His)
B7-H3 Protein, Human, Recombinant (aa 29-245, His)
|
Human | HEK293 Cells |
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet ... | |||
TMPK-01359 | CA125/MUC16 Protein, Human, Recombinant (His & Avi)
CA125/MUC16 Protein, Human, Recombinant (His & Avi)
|
Human | HEK293 Cells |
CA125/MUC16 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 31.3 kDa and the... | |||
TMPK-01365 | CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His & AVI), Biotinylated
CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His & AVI), Biotinylated
|
Human | HEK293 Cells |
CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His & AVI), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecu... | |||
TMPK-01366 | CA125/MUC16 Protein, Human, Recombinant (aa 12660-12923, His & AVI), Biotinylated
CA125/MUC16 Protein, Human, Recombinant (aa 12660-12923, His & AVI), Biotinylated
|
Human | HEK293 Cells |
CA125/MUC16 Protein, Human, Recombinant (aa 12660-12923, His & AVI), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecu... | |||
TMPK-01376 | TROP-2 Protein, Mouse, Recombinant (aa 25-270, His)
TROP-2 Protein, Mouse, Recombinant (aa 25-270, His)
|
Mouse | HEK293 Cells |
Trop-2,also known as epithelial glycoprotein-1 antigen (EGP-1),is a protein that in humans is encoded by the TACSTD2 gene.Mutations of this gene result in gelati... | |||
TMPK-01394 | CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His)
CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His)
|
Human | HEK293 Cells |
CA125/MUC16 Protein, Human, Recombinant (aa 12783-13467, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 76.17 kDa ... |