在实体肿瘤方面CAR-T取得了一定的研究进展,包括食管癌、胃癌、肝癌、结直肠癌、胰腺癌、胆管癌等。与血液瘤相比,实体瘤类型繁多、致病机制多样,靶标选择难度大,在研项目的靶点较为分散。整体来看,Mesothelin、HER2、EGFR、GPC3、GD2、CD276、MUC1、Claudin 18.2(CLDN18.2)等是常见靶点。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-05414 | NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
NKG2D/CD314 Protein, Mouse, Recombinant (hFc)
|
Mouse | Baculovirus-Insect Cells |
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked typ... | |||
TMPY-05587 | EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated
EpCAM/TROP1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF... | |||
TMPY-05641 | B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
B7-H3 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor... |