实体瘤靶点蛋白

在实体肿瘤方面CAR-T取得了一定的研究进展，包括食管癌、胃癌、肝癌、结直肠癌、胰腺癌、胆管癌等。与血液瘤相比，实体瘤类型繁多、致病机制多样，靶标选择难度大，在研项目的靶点较为分散。整体来看，Mesothelin、HER2、EGFR、GPC3、GD2、CD276、MUC1、Claudin 18.2（CLDN18.2）等是常见靶点。

Species：

Expression System：

Tag：

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPY-01945	HER2/ERBB2 Protein, Rhesus, Recombinant (hFc) HER2/ERBB2 Protein, Rhesus, Recombinant (hFc)	Rhesus	HEK293
TMPY-01945	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto...
TMPY-01946	HER2/ERBB2 Protein, Rhesus, Recombinant (His) HER2/ERBB2 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
TMPY-01946	Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto...
TMPY-02068	HGFR/c-Met Protein, Canine, Recombinant (His) HGFR/c-Met Protein, Canine, Recombinant (His)	Canine	HEK293
TMPY-02068	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is over...
TMPY-02417	FOLR1 Protein, Canine, Recombinant (hFc) FOLR1 Protein, Canine, Recombinant (hFc)	Canine	HEK293
TMPY-02417	The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transpo...
TMPY-02666	TROP-2 Protein, Mouse, Recombinant (hFc) TROP-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
TMPY-02666	TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide va...
TMPY-02675	EGFR Protein, Mouse, Recombinant (hFc) EGFR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
TMPY-02675	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in...
TMPY-02678	VEGFR2/KDR Protein, Rat, Recombinant (His) VEGFR2/KDR Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-02678	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr...
TMPY-02736	VEGFR2/KDR Protein, Mouse, Recombinant (His) VEGFR2/KDR Protein, Mouse, Recombinant (His)	Mouse	HEK293
TMPY-02736	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr...
TMPY-02858	VEGFR2/KDR Protein, Mouse, Recombinant (hFc) VEGFR2/KDR Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
TMPY-02858	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr...
TMPY-02871	Mucin-1/MUC1 Protein, Human, Recombinant (mFc) Mucin-1/MUC1 Protein, Human, Recombinant (mFc)	Human	HEK293
TMPY-02871	Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glyc...
TMPY-02939	EpCAM/TROP1 Protein, Rat, Recombinant (His) EpCAM/TROP1 Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-02939	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF...
TMPY-02958	EGFR Protein, Rat, Recombinant (His) EGFR Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-02958	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in...
TMPY-03003	EpCAM/TROP1 Protein, Rat, Recombinant (hFc) EpCAM/TROP1 Protein, Rat, Recombinant (hFc)	Rat	HEK293
TMPY-03003	Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF...
TMPY-03129	CD70 Protein, Rat, Recombinant (hFc) CD70 Protein, Rat, Recombinant (hFc)	Rat	HEK293
TMPY-03129	CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept...
TMPY-03159	CD70 Protein, Rat, Recombinant (His) CD70 Protein, Rat, Recombinant (His)	Rat	HEK293
TMPY-03159	CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept...
TMPY-03202	VEGFR2/KDR Protein, Rat, Recombinant (hFc) VEGFR2/KDR Protein, Rat, Recombinant (hFc)	Rat	HEK293
TMPY-03202	VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr...
TMPY-03581	HGFR/c-Met Protein, Rat, Recombinant (hFc) HGFR/c-Met Protein, Rat, Recombinant (hFc)	Rat	HEK293
TMPY-03581	Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is over...
TMPY-03724	EGFR Protein, Canine, Recombinant (His) EGFR Protein, Canine, Recombinant (His)	Canine	Baculovirus-Insect Cells
TMPY-03724	As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in...
TMPY-03914	B7-H3 Protein, Rat, Recombinant (hFc) B7-H3 Protein, Rat, Recombinant (hFc)	Rat	HEK293
TMPY-03914	B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor...
TMPY-04068	ROR1 Protein, Human, Recombinant (hFc) ROR1 Protein, Human, Recombinant (hFc)	Human	HEK293
TMPY-04068	ROR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 with hFc tag. The predicted molecular weight is 69 kDa. Accession number: Q01973