实体瘤靶点蛋白

在实体肿瘤方面CAR-T取得了一定的研究进展，包括食管癌、胃癌、肝癌、结直肠癌、胰腺癌、胆管癌等。与血液瘤相比，实体瘤类型繁多、致病机制多样，靶标选择难度大，在研项目的靶点较为分散。整体来看，Mesothelin、HER2、EGFR、GPC3、GD2、CD276、MUC1、Claudin 18.2（CLDN18.2）等是常见靶点。

Species：

Expression System：

Tag：

Cat. No.	Product Name / Synonyms	Species	Expression System
TMPK-00308	Nectin-4 Protein, Human, Recombinant (His & Avi) Nectin-4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00308	Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTI...
TMPK-00309	Nectin-4 Protein IgV Domain, Human, Recombinant (His & Avi) Nectin-4 Protein IgV Domain, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00309	Nectin-4 seems to be involved in cell adhesion through trans-homophilic and -heterophilic interactions, the latter including specifically interactions with NECTI...
TMPK-00314	B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00314	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet ...
TMPK-00315	B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00315	B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet ...
TMPK-00336	GPC3 Protein-VLP, Human, Recombinant GPC3 Protein-VLP, Human, Recombinant	Human	E. coli
TMPK-00336	Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size o...
TMPK-00337	GPC3 Protein-VLP, Human, Recombinant (aa 438-554) GPC3 Protein-VLP, Human, Recombinant (aa 438-554)	Human	HEK293
TMPK-00337	Glypican-3 is a protein ,which is encoded by the GPC3 gene in humans.The protein core of GPC3 consists of two subunits, where the N-terminal subunit has a size o...
TMPK-00413	ROR1 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi) ROR1 Protein, Human/Cynomolgus/Rhesus macaque, Recombinant (His & Avi)	Human,Cynomolgus,Rhesus macaque	HEK293
TMPK-00413	ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family w...
TMPK-00425	EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled EGFR Protein, Human, Recombinant (His & Avi), FITC-Labeled	Human	HEK293
TMPK-00425	The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein lig...
TMPK-00426	EGFR Protein, Human, Recombinant (His & Avi) EGFR Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00426	The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein lig...
TMPK-00427	EGFR Protein, Human, Recombinant (His & Avi), Biotinylated EGFR Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00427	The epidermal growth factor receptor is a transmembrane protein that is a receptor for members of the epidermal growth factor family of extracellular protein lig...
TMPK-00428	HER2/ErbB2 Protein, Human, Recombinant (His & Avi) HER2/ErbB2 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00428	ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kin...
TMPK-00429	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi) HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00429	ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kin...
TMPK-00430	HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated HER2/ERBB2 Domain 4 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	HEK293
TMPK-00430	ErbB2, also called Neu and Her2 (human epidermal growth factor receptor 2), is a type I membrane glycoprotein that is a member of the ErbB family of tyrosine kin...
TMPK-00454	VEGFR2/KDR Protein, Human, Recombinant (His & Avi) VEGFR2/KDR Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00454	Tyrosine-protein kinase that acts as a cell-surface receptor for VEGFA, VEGFB and PGF, and plays an essential role in the development of embryonic vasculature, t...
TMPK-00457	HGFR/c-Met Protein, Human, Recombinant (His & Avi) HGFR/c-Met Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00457	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein po...
TMPK-00499	HGFR/c-Met Protein, Cynomolgus, Recombinant (His) HGFR/c-Met Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-00499	c-Met, also called tyrosine-protein kinase Met or hepatocyte growth factor receptor (HGFR), is a protein that in humans is encoded by the MET gene.The protein po...
TMPK-00524	CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His) CA9/Carbonic Anhydrase IX Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-00524	CA9 is a member of the carbonic anhydrases' family, that is often expressed in cancer cells under hypoxic condition. CA9 expression potentially contributes to th...
TMPK-00566	ROR2 Protein, Cynomolgus, Recombinant (His) ROR2 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
TMPK-00566	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...
TMPK-00572	ROR1 Protein, Canine, Recombinant (His) ROR1 Protein, Canine, Recombinant (His)	Canine	HEK293
TMPK-00572	ROR1 (Receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase receptor-related 1 (NTRKR1), is a member of the ROR family w...
TMPK-00577	ROR2 Protein, Human, Recombinant (His & Avi) ROR2 Protein, Human, Recombinant (His & Avi)	Human	HEK293
TMPK-00577	ROR2 (Receptor Tyrosine Kinase-like Orphan Receptor 2) is a member of the ROR family of receptor tyrosine kinases and is important for skeletal development, incl...