在实体肿瘤方面CAR-T取得了一定的研究进展,包括食管癌、胃癌、肝癌、结直肠癌、胰腺癌、胆管癌等。与血液瘤相比,实体瘤类型繁多、致病机制多样,靶标选择难度大,在研项目的靶点较为分散。整体来看,Mesothelin、HER2、EGFR、GPC3、GD2、CD276、MUC1、Claudin 18.2(CLDN18.2)等是常见靶点。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-04128 | FOLR1 Protein, Rat, Recombinant (hFc)
FOLR1 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transpo... | |||
TMPY-04279 | B7-H3 Protein, Mouse, Recombinant (His), Biotinylated
B7-H3 Protein, Mouse, Recombinant (His), Biotinylated
|
Mouse | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor... | |||
TMPY-04284 | B7-H3 Protein, Rat, Recombinant (His)
B7-H3 Protein, Rat, Recombinant (His)
|
Rat | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor... | |||
TMPY-04379 | HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST)
HGFR/c-Met Protein, Human, Recombinant (aa 956-1390, His & GST)
|
Human | Baculovirus-Insect Cells |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is over... | |||
TMPY-04428 | ROR1 Protein, Human, Recombinant (aa 453-783, His & GST)
ROR1 Protein, Human, Recombinant (aa 453-783, His & GST)
|
Human | Baculovirus-Insect Cells |
ROR1 Protein, Human, Recombinant (aa 453-783, His & GST) is expressed in Baculovirus-Insect Cells with His and GST tag. The predicted molecular weight is 65.3 kD... | |||
TMPY-04497 | CD70 Protein, Mouse, Recombinant (mFc)
CD70 Protein, Mouse, Recombinant (mFc)
|
Mouse | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept... | |||
TMPY-04530 | VEGFR2/KDR Protein, Human, Recombinant (His & GST)
VEGFR2/KDR Protein, Human, Recombinant (His & GST)
|
Human | Baculovirus-Insect Cells |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-04538 | HER2/ERBB2 Protein, Human, Recombinant (aa 676-1255, His & GST)
HER2/ERBB2 Protein, Human, Recombinant (aa 676-1255, His & GST)
|
Human | Baculovirus-Insect Cells |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... | |||
TMPY-04585 | B7-H3 Protein, Cynomolgus, Recombinant (His)
B7-H3 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor... | |||
TMPY-04794 | VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, hFc)
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-04795 | VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
VEGFR2/KDR Protein, Human, Recombinant (Domain 1&2&3, His)
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-04796 | VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, His)
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-04802 | VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
VEGFR2/KDR Protein, Human, Recombinant (Domain 2&3, hFc)
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-04924 | VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated
VEGFR2/KDR Protein, Mouse, Recombinant (His), Biotinylated
|
Mouse | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-04940 | VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated
VEGFR2/KDR Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-04953 | EpCAM/TROP1 Protein, Human, Recombinant (His), Biotinylated
EpCAM/TROP1 Protein, Human, Recombinant (His), Biotinylated
|
Human | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF... | |||
TMPY-04955 | HER2/ERBB2 Protein, Human, Recombinant (His), Amine-Labeled Biotinylated
HER2/ERBB2 Protein, Human, Recombinant (His), Amine-Labeled Biotinylated
|
Human | HEK293 |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... | |||
TMPY-04977 | CD70 Protein, Human, Recombinant (mFc)
CD70 Protein, Human, Recombinant (mFc)
|
Human | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept... | |||
TMPY-04982 | CD70 Protein, Human, Recombinant (rFc)
CD70 Protein, Human, Recombinant (rFc)
|
Human | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept... | |||
TMPY-04986 | ROR1 Protein, Human, Recombinant, Biotinylated
ROR1 Protein, Human, Recombinant, Biotinylated
|
Human | HEK293 |
ROR1 Protein, Human, Recombinant, Biotinylated is expressed in HEK293. The predicted molecular weight is 42.8 kDa. Accession number: Q01973 |