在实体肿瘤方面CAR-T取得了一定的研究进展,包括食管癌、胃癌、肝癌、结直肠癌、胰腺癌、胆管癌等。与血液瘤相比,实体瘤类型繁多、致病机制多样,靶标选择难度大,在研项目的靶点较为分散。整体来看,Mesothelin、HER2、EGFR、GPC3、GD2、CD276、MUC1、Claudin 18.2(CLDN18.2)等是常见靶点。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-00128 | EGFR Protein, Rhesus, Recombinant (hFc)
EGFR Protein, Rhesus, Recombinant (hFc)
|
Rhesus | HEK293 |
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in... | |||
TMPY-00268 | B7-H3 Protein, Cynomolgus, Recombinant (hFc)
B7-H3 Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor... | |||
TMPY-00465 | HER2/ERBB2 Protein, Cynomolgus, Recombinant (hFc)
HER2/ERBB2 Protein, Cynomolgus, Recombinant (hFc)
|
Cynomolgus | HEK293 |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... | |||
TMPY-00533 | EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant (hFc)
|
Cynomolgus,Rhesus | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF... | |||
TMPY-00534 | EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant
EpCAM/TROP1 Protein, Cynomolgus, Rhesus, Recombinant
|
Cynomolgus,Rhesus | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF... | |||
TMPY-00543 | FOLR1 Protein, Rat, Recombinant (His)
FOLR1 Protein, Rat, Recombinant (His)
|
Rat | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transpo... | |||
TMPY-00546 | HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (hFc)
HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant (hFc)
|
Cynomolgus,Rhesus | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is over... | |||
TMPY-00622 | FOLR1 Protein, Canine, Recombinant (His)
FOLR1 Protein, Canine, Recombinant (His)
|
Canine | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transpo... | |||
TMPY-00634 | HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant
HGFR/c-Met Protein, Cynomolgus, Rhesus, Recombinant
|
Cynomolgus,Rhesus | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is over... | |||
TMPY-00643 | B7-H3 Protein, Human, Recombinant (hFc)
B7-H3 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
B7-H3 is a member of the B7 family of immune regulatory ligands that is thought to attenuate peripheral immune responses through co-inhibition. It plays an impor... | |||
TMPY-00718 | HGFR/c-Met Protein, Human, Recombinant (His & hFc)
HGFR/c-Met Protein, Human, Recombinant (His & hFc)
|
Human | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is over... | |||
TMPY-00745 | HER2/ERBB2 Protein, Human, Recombinant (hFc)
HER2/ERBB2 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... | |||
TMPY-00785 | EpCAM/TROP1 Protein, Human, Recombinant (hFc)
EpCAM/TROP1 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF... | |||
TMPY-00946 | TROP-2 Protein, Human, Recombinant (His & hFc)
TROP-2 Protein, Human, Recombinant (His & hFc)
|
Human | HEK293 |
TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide va... | |||
TMPY-01043 | EGFR Protein, Human, Recombinant (hFc)
EGFR Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in... | |||
TMPY-01044 | VEGFR2/KDR Protein, Human, Recombinant (hFc)
VEGFR2/KDR Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
VEGFR2 also called KDR or Flk-1, is identified as the receptor for VEGF and VEGFC and an early marker for endothelial cell progenitors, whose expression is restr... | |||
TMPY-01766 | EpCAM/TROP1 Protein, Mouse, Recombinant (His)
EpCAM/TROP1 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF... | |||
TMPY-01895 | HGFR/c-Met Protein, Mouse, Recombinant (hFc)
HGFR/c-Met Protein, Mouse, Recombinant (hFc)
|
Mouse | HEK293 |
Hepatocyte growth factor receptor (HGFR), also known as c-Met or mesenchymal-epithelial transition factor (MET), is a receptor tyrosine kinase (RTK) that is over... | |||
TMPY-01942 | HER2/ERBB2 Protein, Rat, Recombinant
HER2/ERBB2 Protein, Rat, Recombinant
|
Rat | HEK293 |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... | |||
TMPY-01943 | HER2/ERBB2 Protein, Rat, Recombinant (hFc)
HER2/ERBB2 Protein, Rat, Recombinant (hFc)
|
Rat | HEK293 |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... |