在实体肿瘤方面CAR-T取得了一定的研究进展,包括食管癌、胃癌、肝癌、结直肠癌、胰腺癌、胆管癌等。与血液瘤相比,实体瘤类型繁多、致病机制多样,靶标选择难度大,在研项目的靶点较为分散。整体来看,Mesothelin、HER2、EGFR、GPC3、GD2、CD276、MUC1、Claudin 18.2(CLDN18.2)等是常见靶点。
Cat. No. | Product Name / Synonyms | Species | Expression System |
---|---|---|---|
TMPY-06720 | TROP-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
TROP-2 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 |
TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide va... | |||
TMPY-06751 | Glypican 3/GPC3 Protein, Canine, Recombinant (His)
Glypican 3/GPC3 Protein, Canine, Recombinant (His)
|
Canine | HEK293 |
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed... | |||
TMPY-06770 | CD70 Protein, Mouse, Recombinant (His & Avi), Biotinylated
CD70 Protein, Mouse, Recombinant (His & Avi), Biotinylated
|
Mouse | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept... | |||
TMPY-06790 | CD70 Protein, Mouse, Recombinant (His)
CD70 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept... | |||
TMPY-06820 | Glypican 3/GPC3 Protein, Cynomolgus, Recombinant (His)
Glypican 3/GPC3 Protein, Cynomolgus, Recombinant (His)
|
Cynomolgus | HEK293 |
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed... | |||
TMPY-06825 | ROR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
ROR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 |
ROR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 with AVI and hFc tag. The predicted molecular weight is 70.53 kDa. Accession nu... | |||
TMPY-06827 | NKG2D/CD314 Protein, Human, Recombinant (mFc)
NKG2D/CD314 Protein, Human, Recombinant (mFc)
|
Human | Baculovirus-Insect Cells |
KLRK1 (Killer Cell Lectin Like Receptor K1) is a Protein Coding gene. NKG2D, also known as CD314, is an immune receptor that consists of two disulfide-linked typ... | |||
TMPY-06832 | Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-380, His)
Mucin-1/MUC1 Protein, Human, Recombinant (aa 1-380, His)
|
Human | HEK293 |
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glyc... | |||
TMPY-06833 | Mucin-1/MUC1 Protein, Human, Recombinant (aa 890-1158, His)
Mucin-1/MUC1 Protein, Human, Recombinant (aa 890-1158, His)
|
Human | HEK293 |
Mucin 1, cell surface-associated (MUC1) or polymorphic epithelial mucin (PEM) is a membrane-bound protein that is a member of the mucin family. Mucins are O-glyc... | |||
TMPY-06849 | EpCAM/TROP1 Protein, Human, Recombinant (mFc)
EpCAM/TROP1 Protein, Human, Recombinant (mFc)
|
Human | HEK293 |
Epithelial Cell Adhesion Molecule (EpCAM), also known as GA733-2 antigen, is a type I transmembrane glycoprotein composed of an extracellular domain with two EGF... | |||
TMPY-06850 | ROR2 Protein, Mouse, Recombinant (His)
ROR2 Protein, Mouse, Recombinant (His)
|
Mouse | HEK293 |
ROR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 with His tag. The predicted molecular weight is 42.64 kDa. Accession number: Q9Z138 | |||
TMPY-06856 | HER2/ERBB2 Protein, Cynomolgus, Recombinant (His & Avi)
HER2/ERBB2 Protein, Cynomolgus, Recombinant (His & Avi)
|
Cynomolgus | HEK293 |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... | |||
TMPY-06877 | Glypican 3/GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated
Glypican 3/GPC3 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
Glypican-3, also known as Intestinal protein OCI-5, GPC3, and OCI5, is a member of the glypican family. It belongs to the glypican family and is highly expressed... | |||
TMPY-06928 | FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
FOLR1 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transpo... | |||
TMPY-06929 | FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated
FOLR1 Protein, Human, Recombinant (His & Avi), Biotinylated
|
Human | HEK293 |
The protein encoded by FOLR1 gene is a member of the folate receptor family. Members of this gene family bind folic acid and its reduced derivatives, and transpo... | |||
TMPY-06953 | CD70 Protein, Human, Recombinant (His)
CD70 Protein, Human, Recombinant (His)
|
Human | HEK293 |
CD70, a member of the tumor necrosis factor superfamily, is restricted to activated T-and B-lymphocytes and mature dendritic cells. Binding of CD70 to its recept... | |||
TMPY-06958 | Nectin-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
Nectin-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated
|
Human | HEK293 |
Nectin-4 Protein, Human, Recombinant (hFc & Avi), Biotinylated is expressed in HEK293 with hFc and AVI tag. The predicted molecular weight is 62.65 kDa. Accessio... | |||
TMPY-06972 | TROP-2 Protein, Human, Recombinant (hFc)
TROP-2 Protein, Human, Recombinant (hFc)
|
Human | HEK293 |
TROP-2, also referred to as tumor-associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1, is a cell surface glycoprotein highly expressed in a wide va... | |||
TMPY-04684 | HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His)
HER2/ERBB2 Protein, Human, Recombinant (aa 1-195, His)
|
Human | HEK293 |
Human epidermal growth factor receptor 2 (HER2), also known as ErbB2, NEU, and CD340, is a type I membrane glycoprotein and belongs to the epidermal growth facto... | |||
TMPY-00742 | EGFR Protein, Human, Recombinant (His)
EGFR Protein, Human, Recombinant (His)
|
Human | HEK293 |
As a member of the epidermal growth factor receptor (EGFR) family, EGFR protein is type I transmembrane glycoprotein that binds a subset of EGF family ligands in... |