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75

抑制剂 & 化合物

23

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T10303	Aminoacyl tRNA synthetase-IN-1	Others	Others
	Aminoacyl tRNA synthetase-IN-1 is an inhibitor of bacterial aminoacyl tRNA synthetase (aaRS).
T74612	Aminoacyl tRNA synthetase-IN-2
	Aminoacyl tRNA synthetase-IN-2 (Compound 14) 是氨酰基-tRNA 合成酶 (aaRS) 抑制剂，可用于新型抗生素家族的开发。
T63688	Isoleucyl tRNA synthetase-IN-1
	Isoleucyl tRNA synthetase-IN-1 是选择性的、有效的靶向异亮基 tRNA 合成酶 (IleRS) 的抑制剂 (Ki: 88 nM)。
T9726	2’-OMe-Guanosine	Apoptosis; Nucleoside Antimetabolite/Analog	Apoptosis; Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2'-O-Methylguanosine 是一种修饰核苷，是tRNA 上的核苷在 tRNA 鸟苷-2’-o-甲基转移酶作用下产生的。2'-O-Methylguanosine 具有一定的促凋亡作用。
T63706	Isoleucyl tRNA synthetase-IN-2
	Isoleucyl tRNA synthetase-IN-2 是选择性的、有效的靶向异亮基 tRNA 合成酶 (IleRS) 的抑制剂 (Ki: 114 nM)。
T9533	BC-LI-0186 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide	Others	Others
	BC-LI-0186 (4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide) 是选择性抑制亮氨酸 tRNA 合成酶与 Ras 相关的 GTP 结合蛋白 D 相互作用(IC50=46.11 nM)。BC-LI-0186能有效抑制肿瘤相关 MTOR 突变体的特性和雷帕霉素耐药癌细胞的生长，能够用于肺癌的相关研究。
T41286	N6-Isopentenyladenosine	Endogenous Metabolite; Autophagy	Autophagy; Metabolism
	N6-Isopentenyladenosine 是甲羟戊酸途径的终产物，是一种具有抗黑色素瘤活性的自噬抑制剂。 N6-Isopentenyladenosine 是一种在细胞分裂素中发现的 RNA 修饰，可调节植物生长/分化，提高翻译的效率和准确性。
T16698	Pyronin Y C.I. 45005,派洛宁Y,派洛宁 Y,Pyronine G	Others	Others
	Pyronin Y (Pyronine G) 是一种可插入 RNA 的阳离子染料，可以靶向包括 RNA，DNA 和细胞器的细胞结构。它能够与双链核酸(尤其是 RNA) 形成荧光复合物，半定量分析细胞 RNA。它可用于活细胞中核糖核蛋白复合物的特定 RNA 亚种的鉴定。
T0788L	Spectinomycin dihydrochloride pentahydrate 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride pentahydrate (Spectogard) 是一种广谱氨基环糊精抗生素，可以抑制多种革兰氏阳性和革兰氏阴性生物的生长。
T78227	L-Methioninamide hydrochloride	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	L-Methioninamide hydrochloride 是一种有效的甲硫氨酰-tRNA 合成酶 (Methionyl-tRNA synthetase) 抑制剂，能够降低CDDP毒性。
T11919	LysRs-IN-1 9-carboxymethylguanine	Others	Others
	LysRs-IN-1是一种赖氨酰-tRNA 合成酶（LysRs）的抑制剂。
T19464	N6,N6-Dimethyladenosine N6,N6-二甲基腺苷	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	N6,N6-Dimethyladenosine 是存在于牛分枝杆菌 tRNA 中的一种修饰核糖核苷
T4045	Epetraborole hydrochloride GSK2251052 hydrochloride	Antibacterial	Microbiology/Virology
	Epetraborole hydrochloride (GSK2251052 hydrochloride) 是一个新型 LeuRS 抑制剂，通过绑定 leucyl-tRNA 合成酶终端的腺苷核糖抑制蛋白合成，可研究 Gram-negative 细菌引起的感染。
T11497	Ganfeborole HCl GSK3036656 HCl,GSK656 HCl	Antibacterial	Microbiology/Virology
	Ganfeborole HCl (GSK3036656 HCl) 是一种具有抗结核活性的小分子化合物，是结核分枝杆菌（Mtb）亮氨酰-tRNA 合成酶（LeuRS；IC50：0.2 μM）的抑制剂。
T8629	N-BENZYL-2-PHENYLETHYLAMINE	Others	Others
	N-BENZYL-2-PHENYLETHYLAMINE 是 rel+ Escherichia coli B Phe-tRNA 的抑制剂。
T3052	Sancycline Bonomycin,Norcycline,Sancyclinum,山环素,6-Demethyl-6-deoxytetracycline	Antibacterial	Microbiology/Virology
	Sancycline (Bonomycin) 是半合成四环素，通过可逆地结合 30S 核糖体亚基并通过阻断氨酰-tRNA 进入核糖体 A 位点来抑制蛋白质翻译。
T20121	L-Albizziin NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin,L-脲基丙氨酸	Glutaminase	Proteases/Proteasome
	L-Albizziin (L-beta-Ureidoalanine) 是一种巯基试剂，是一种谷氨酰胺酶抑制剂，可用于研究癌症。
T50026	Aquacycline	HSV	Microbiology/Virology
	Aquacycline 是一种广谱抗生素，通过抑制细菌中的蛋白质合成起作用。它可防止氨酰-tRNA 与复杂的 m-核糖体 RNA 结合。它还具有抗 HSV-1 活性。
T1569	Tigecycline 替加环素,GAR-936	ribosome; Antibacterial; Antibiotic; Autophagy	Autophagy; Microbiology/Virology
	Tigecycline (GAR-936) 是甘氨酰环素抗生素，对 Acinetobacter baumannii(A. baumannii) 的 MIC50和 MIC90分别为 1 和 2 mg/L。它对 E. coli(MG1655 菌株) 的平均抑制浓度 (MIC) 约 125 ng/ mL。
T8785	HALOFUGINONE LACTATE	DNA/RNA Synthesis; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Stem Cells
	HALOFUGINONE LACTATE 是 febrifugine 的卤化衍生物，它是一种天然的含有喹唑啉酮的化合物，存在于中草药 D. febrifuga 中。Halofuginone 以 ATP 依赖性方式抑制脯氨酰-tRNA 合成酶，Ki 为 18.3 nM。 Halofuginone 是 I 型胶原合成的特异性抑制剂，通过抑制 TGF-β 活性来减轻骨关节炎 (OA)
T8404	Kasugamycin hydrochloride hydrate Ksg (hydrochloride hydrate),春雷霉素盐酸盐一水合物	Antibacterial; Antibiotic	Microbiology/Virology
	Kasugamycin hydrochloride hydrate (Ksg (hydrochloride hydrate)) 是一种能结合 30s 和 70s 核糖体，但不能结合 50s 亚基的抗生素。它模拟 mRNA 核苷酸破坏 tRNA 结合并抑制典型翻译起始。
TNU0130	2'-O-Methyl-2-thiouridine	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	2'-O-Methyl-2-thiouridine 是一种存在于合成嗜热细菌tRNA中的嘌呤核苷类似物。2'-O-Methyl-2-thiouridine 对 A 的选择性高于未修饰的 U。
T31932	GJ071 oxalate GJ 071,GJ-071,GJ071	Others	Others
	GJ071 oxalate 是一种无义抑制剂。无义抑制剂（NonSups）诱导“读出”，即在提前终止密码子处选择近同源tRNA，并将相应的氨基酸插入新生多肽中。
T22774L	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)	Others	Others
	eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species](TFA) 是延伸因子 1 亚基。真核翻译延伸因子 1 alpha 1 (EEF1A1) 编码延伸因子 alpha 亚基的同种型- 1 复合物，负责将氨酰 tRNA 酶促递送至核糖体。这种亚型（α 1）在脑、胎盘、肺、肝、肾和胰腺中表达，另一种亚型（α 2）在脑、心脏和骨骼肌中表达。这种亚型在 66% 的 Felty 综合征患者中被鉴定为自身抗原。已发现该基因在许多染色体上具有多个拷贝，其中一些（如果不是全部）代表不同的假基因。
T11920	LysRs-IN-2	Others	Others
	LysRs-IN-2 is a lysyl-tRNA synthetase (KRS) inhibitor with IC50s of 0.13 μM and 0.015 μM for Cryptosporidium parvum lysyl-tRNA synthetase (CpKRS) and Plasmodium falciparum lysyl-tRNA synthetase (PfKRS), respectively.
T64165	Gln-AMS TFA
	Gln-AMS (TFA) 是一种 Ia 类型的氨酰基-tRNA 合成酶 (AARS) 抑制剂，对谷氨酰胺酰-tRNA 合成酶的Ki 值为1.32 μM。
T11434	GlyRS-IN-1	Others	Others
	GlyRS-IN-1 is an inhibitor of glycyl-tRNA synthase (GlyRS). It can inhibit the growth of bacteria.
T11403	Gln-AMS	Others	Others
	Gln-AMS is an inhibitor of aminoacyl-tRNA synthetases (AARS). It specifically binds to the A-domain located within the NRPS enzymes.
T26178	SB-217452 SB217452
	SB-217452 is a potent seryl tRNA synthetase inhibitor isolated from Streptomyces.
T71168	Epetraborole R-Mandelate
	Epetraborole R-Mandelate is a potent and selective leucyl-tRNA synthetase inhibitor.
T11403L	Gln-AMS TFA (209543-57-7 free base) Gln-AMS TFA	Others	Others
	Gln-AMS(TFA) inhibits glutaminyl-tRNA synthetase (GlnRS) with a Ki of 1.32 μM. Gln-AMS (TFA) is a type Ia aminoacyl-tRNA synthetase (AARS) inhibitor.
T26314	Valyl-ochratoxin A
	Valyl-ochratoxin A is a phenylalanyl moiety of ochratoxin A replaced by valine. It is a yeast valyl-tRNA synthetase inhibitor.
T61676	4-Piperidinecarboxamide
	4-Piperidinecarboxamide is a mycobacterial aspartyl-tRNA synthetase (AspS) inhibitor and a potential anti-tuberculosis (TB) agent [1].
T72349	Antibacterial agent 91
	Antibacterial agent 91 是一种氨酰基-tRNA 合成酶 (aaRS) 抑制剂，对 Salmonella enterica 苏氨酰-tRNA 合成酶 (SeThrRS) 的 IC50为 2.10 μM。Antibacterial agent 91 具有抗细菌活性。
T27088	CRS-3123 REP-3123,REP 3123,CRS 3123
	CRS-3123, a methionyl-tRNA synthetase inhibitor, is used potentially for the treatment of enteric infections.
T10365	Arg-AMS	Others	Others
	Arg-AMS is a potent arginyl tRNA synthetase inhibitor that displays tightly bound inhibitory characteristics for the A-domains in non-ribosomal peptide synthetases (NRPS) enzymes.
T40561	ThrRS-IN-2
	ThrRS-IN-2 is a threonyl-tRNA synthetase (ThrRS) inhibitor with an IC 50 value of 56.5 ± 3.5 μM.
T72303	Antibacterial agent 124
	Antibacterial agent 124 是一种有效的细菌脯氨酸-tRNA 合成酶 (ProRS) 抑制剂，对 Staphylococcus aureusProRS (SaProRS) 的 IC50为 0.18 μM。
T72350	Antibacterial agent 92
	Antibacterial agent 92 是一种氨酰基-tRNA 合成酶 (aaRS) 抑制剂，对 Salmonella enterica 苏氨酰-tRNA 合成酶 (SeThrRS) 的 IC50为 0.58 μM。Antibacterial agent 92 具有抗细菌活性。
T69741	DWN-12088 HCl
	DWN-12088 HCl is the salt form of DWN-12088 Free Base, an orally administered small molecule prolyl-tRNA synthetase (PRS) inhibitor
T63376	CB 168
	CB 168是有效的靶向异亮基 tRNA 合成酶 (IleRS) 选择性氨基酰基氨基酰芳基四唑抑制剂。
T71901	MP-1
	MP-1 is a covalent inhibitor of fumarate hydratase (FH) that exhibits cytotoxicity dependent on FH. MP-1 engages a functional cysteine in the Zn-finger domain of the tRNA methyltransferase enzyme TRMT1.
T10386	Asp-AMS	Others	Others
	Asp-AMS is a strong competitive inhibitor of the mitochondrial enzyme and also an aspartyl-tRNA synthetase inhibitor.
T33511	ms2i6A ms2i6-2-6,ms2i6 2 6
	ms2i6A is a mitochondrial tRNA-specific modification, which regulates efficient mitochondrial translation and energy metabolism in mammals.
T26001	Pulvomycin Antibiotic 1063Z
	Pulvomycin is a protein biosynthesis inhibitor preventing ternary complex formation between elongation factor Tu, GTP, and aminoacyl-tRNA.
T60405	GSK-3036656 free base GSK656 HCl,GSK 3036656,GSK656,GSK-3036656,GSK-656,GSK 656
	GSK656 (GSK3036656) 可有效抑制结核分枝杆菌 (Mtb) 亮氨酰-tRNA 合成酶 (LeuRS) (IC50 = 0.20 μM)，具有治疗结核病的潜力。
T21052	Lysidine 2-甲基咪唑啉,2-Methyl-2-iMidazoline	Nucleoside Antimetabolite/Analog	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Lysidine (2-Methyl-2-iMidazoline) 是在 tRNA 之外很少见到的核苷。 Lysidine 具有更好的翻译保真度。
T72351	Antibacterial agent 93
	Antibacterial agent 93是一种有效的氨酰基-tRNA 合成酶 (aaRS)抑制剂。Antibacterial agent 93 对一些革兰氏阳性和阴性细菌均显示出抗菌活性。
T60974	MetRS-IN-1
	MetRS-IN-1 (Compound 27) 是大肠杆菌甲硫氨酰-tRNA 合成酶 (MetRS) 抑制剂，IC50值为237 nM。
T11841	Leu-AMS R enantiomer	Others	Others
	Leu-AMS R enantiomer 是 Leu-AMS 的 R 对映体。 Leu-AMS 是一种有效的亮氨酰-tRNA 合成酶 (LRS) 抑制剂，可抑制细菌的生长。

化合物

Aminoacyl tRNA synthetase-IN-1

Cat.No: T10303

Target: Others

Aminoacyl tRNA synthetase-IN-2

Cat.No: T74612

Isoleucyl tRNA synthetase-IN-1

Cat.No: T63688

2’-OMe-Guanosine

Cat.No: T9726

Target: Apoptosis, Nucleoside Antimetabolite/Analog

Isoleucyl tRNA synthetase-IN-2

Cat.No: T63706

Cat.No: T9533

Synonym: 4-(2,3-dimethyl-5-oxo-4-propan-2-ylpyrazol-1-yl)-N-(2-phenoxyethyl)benzenesulfonamide

Target: Others

N6-Isopentenyladenosine

Cat.No: T41286

Target: Endogenous Metabolite, Autophagy

Cat.No: T16698

Synonym: C.I. 45005,派洛宁Y,派洛宁 Y,Pyronine G

Target: Others

Spectinomycin dihydrochloride pentahydrate

Cat.No: T0788L

Synonym: 盐酸大观霉素五水合物,Trobicin,Spectogard,Spectinomycin hydrochloride hydrate

Target: ribosome, Antibacterial, Antibiotic

L-Methioninamide hydrochloride

Cat.No: T78227

Target: DNA/RNA Synthesis

Cat.No: T11919

Synonym: 9-carboxymethylguanine

Target: Others

N6,N6-Dimethyladenosine

Cat.No: T19464

Synonym: N6,N6-二甲基腺苷

Target: Nucleoside Antimetabolite/Analog

Epetraborole hydrochloride

Cat.No: T4045

Synonym: GSK2251052 hydrochloride

Target: Antibacterial

Ganfeborole HCl

Cat.No: T11497

Synonym: GSK3036656 HCl,GSK656 HCl

Target: Antibacterial

N-BENZYL-2-PHENYLETHYLAMINE

Cat.No: T8629

Target: Others

Cat.No: T3052

Synonym: Bonomycin,Norcycline,Sancyclinum,山环素,6-Demethyl-6-deoxytetracycline

Target: Antibacterial

Cat.No: T20121

Synonym: NSC-132089,L-beta-Ureidoalanine,L-Albizziine,Albizzine,NSC 132089,Albizziin,L-脲基丙氨酸

Target: Glutaminase

Cat.No: T50026

Target: HSV

Cat.No: T1569

Synonym: 替加环素,GAR-936

Target: ribosome, Antibacterial, Antibiotic, Autophagy

HALOFUGINONE LACTATE

Cat.No: T8785

Target: DNA/RNA Synthesis, TGF-beta/Smad

Kasugamycin hydrochloride hydrate

Cat.No: T8404

Synonym: Ksg (hydrochloride hydrate),春雷霉素盐酸盐一水合物

Target: Antibacterial, Antibiotic

2'-O-Methyl-2-thiouridine

Cat.No: TNU0130

Target: Nucleoside Antimetabolite/Analog

Cat.No: T31932

Synonym: GJ 071,GJ-071,GJ071

Target: Others

eukaryotic translation elongation factor 1 alpha 1 (EEF1A1) (387-394) [Multiple species]（TFA)

Cat.No: T22774L

Target: Others

Cat.No: T11920

Target: Others

Cat.No: T64165

Cat.No: T11434

Target: Others

Cat.No: T11403

Target: Others

Cat.No: T26178

Synonym: SB217452

Epetraborole R-Mandelate

Cat.No: T71168

Gln-AMS TFA (209543-57-7 free base)

Cat.No: T11403L

Synonym: Gln-AMS TFA

Target: Others

Valyl-ochratoxin A

Cat.No: T26314

4-Piperidinecarboxamide

Cat.No: T61676

Antibacterial agent 91

Cat.No: T72349

Cat.No: T27088

Synonym: REP-3123,REP 3123,CRS 3123

Cat.No: T10365

Target: Others

Cat.No: T40561

Antibacterial agent 124

Cat.No: T72303

Antibacterial agent 92

Cat.No: T72350

Cat.No: T69741

Cat.No: T63376

Cat.No: T71901

Cat.No: T10386

Target: Others

Cat.No: T33511

Synonym: ms2i6-2-6,ms2i6 2 6

Cat.No: T26001

Synonym: Antibiotic 1063Z

GSK-3036656 free base

Cat.No: T60405

Synonym: GSK656 HCl,GSK 3036656,GSK656,GSK-3036656,GSK-656,GSK 656

Cat.No: T21052

Synonym: 2-甲基咪唑啉,2-Methyl-2-iMidazoline

Target: Nucleoside Antimetabolite/Analog

Antibacterial agent 93

Cat.No: T72351

Cat.No: T60974

Leu-AMS R enantiomer

Cat.No: T11841

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0895	Oxytetracycline 土霉素,Terramycin	ribosome; Endogenous Metabolite; Antibacterial; Antibiotic; HSV	Metabolism; Microbiology/Virology
	Oxytetracycline (Terramycin) 是一种四环素类抗生素。它强力抑制革兰氏阴性和革兰氏阳性细菌。它是一种蛋白质合成抑制剂，可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合，具有抗 HSV-1的活性。
T6624	Oxytetracycline Dihydrate 土霉素二水合物,地霉素,Terramycin Dihydrate	Others; Endogenous Metabolite; Antibacterial; Antibiotic; HSV	Metabolism; Microbiology/Virology; Others
	Oxytetracycline Dihydrate (Terramycin Dihydrate) 是一种四环素类抗生素，可抑制革兰氏阴性和革兰氏阳性细菌。它是一种蛋白质合成抑制剂，可阻止 aminoacil-tRNA 与复杂的核糖体 RNA 结合，还具有抗 HSV-1的活性。
T0788	Spectinomycin dihydrochloride 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Spectinomycin dihydrochloride (Actinospectacin) 是一种能与细菌核糖体的30S 亚基结合，干扰蛋白质合成的抗生素。
T21430	Oxytetracycline Hydrochloride Biosolvomycin,盐酸土霉素,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin	Antiviral; Endogenous Metabolite; Antibacterial; HSV	Immunology/Inflammation; Metabolism; Microbiology/Virology
	Oxytetracycline Hydrochloride (Dalimycin) 是由 Streptomyces rimosus 生产的，一种具有抗菌活性的四环素衍生物。它干扰氨酰-tRNA 与 mRNA-核糖体复合物的结合，从而阻止肽延伸并抑制蛋白质合成。
T6856	Halofuginone 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110	Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Stem Cells
	Halofuginone (RU-19110) 是Febrifugine 的衍生物，是一种竞争性脯氨酰-tRNA 合成酶抑制剂。它也是肺血管扩张剂，可激活Kv 通道并阻断电压门控、受体操作和存储操作的钙离子通道。它具有抗炎、抗癌、抗疟疾和抗纤维化作用。
T3524	Halofuginone hydrobromide 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐	Others; Calcium Channel; DNA/RNA Synthesis; Sodium Channel; Parasite; TGF-beta/Smad	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology; Others; Stem Cells
	Halofuginone hydrobromid 是Febrifugine 的衍生物，是竞争性脯氨酰-tRNA 合成酶抑制剂。它是 I 型胶原合成的特异性抑制剂，并通过抑制TGF-β活性可减轻骨关节炎。它具有抗疟疾、抗炎、抗癌、抗纤维化作用。
T19083	1-Methylinosine N1-Methylinosine,Inosine, 1-methyl,1-甲基肌苷	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	1-Methylinosine (N1-Methylinosine) 是在真核生物 tRNA 反密码子 3' 位 tRNA 的 37 位上发现的修饰核苷酸，具有代谢物的作用。
T19146	5,6-Dihydrouridine	Endogenous Metabolite	Metabolism
	5,6-Dihydrouridine 是一种修饰碱基，存在于真核生物、细菌和某些古细菌tRNA D 环的保守位置。
TN7106	2′-O-Methyluridine	Others	Others
	2'-O-methyluridine 是一种存在于古生菌、细菌和真核生物中的 rRNA、snRNA、snoRNA 和 tRNA 等 RNA 中的天然产物。
T0912L	Tetracycline Deschlorobiomycin,Tetracyclinum,Tetracyclin,四环素	Others; ribosome; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Tetracycline (Tetracyclin) 是一种对多种革兰氏阳性和革兰氏阴性细菌有抑制活性的广谱抗生素。
T7514	N2-Methylguanosine 2-甲鳥苷	Nucleoside Antimetabolite/Analog; Endogenous Metabolite	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Metabolism
	N2-Methylguanosine 是一种修饰核苷，出现在许多 tRNA 的几个特定位点。
T6447	Clindamycin Clinimycin,Sobelin,Chlolincocin,克林霉素	Antibacterial; Antibiotic	Microbiology/Virology
	Clindamycin (Sobelin) 从细菌核糖体中解离肽基-tRNA，破坏细菌蛋白质合成。它是一种半合成广谱抗生素，由母体化合物林可霉素化学修饰而成。
T4456	N4-Acetylcytidine N4-乙酰胞苷,N-Acetylcytidine	Others; Endogenous Metabolite	Metabolism; Others
	N4-Acetylcytidine (N-Acetylcytidine) 是内源性代谢产物的一种。
T5055	For-Met-OH fMet,N-甲酰甲硫氨酸,N-Formyl-L-methionine	Others; Endogenous Metabolite	Metabolism; Others
	For-Met-OH (N-Formyl-L-methionine) 是内源性代谢产物的一种。
T6599	N6-methyladenosine N6-甲基腺苷,N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A	Others; Influenza Virus; Endogenous Metabolite	Metabolism; Microbiology/Virology; Others
	N6-methyladenosine (NSC-29409) 是甲基化的腺嘌呤残基，苷是转移核糖核酸降解的内源性尿核苷产物。它是存在于所有高等真核生物中普遍的的信使 RNA 内部修饰，可修饰病毒 RNA，有抗病毒活性。
TL0005	3,5-O-Dicaffeoylquinic acid Isochlorogenic Acid A,(-)-3,5-二咖啡酰奎宁酸,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid	Others	Others
	3,5-O-Dicaffeoylquinic acid (Isochlorogenic Acid A) 能够改善由三甲基锡诱导的学习和记忆缺陷。
T0912	Tetracycline hydrochloride NCI-c55561,盐酸四环素,Tetracycline HCl	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Tetracycline hydrochloride (NCI-c55561) 是一种广谱抗生素，抑制多种革兰氏阳性和革兰氏阴性细菌。
TQ0193	N2,N2-Dimethylguanosine N2,N2-二甲基鸟苷	Endogenous Metabolite	Metabolism
	N2,N2-Dimethylguanosine 是尿核苷，是 tRNA 的初级代谢产物。
T2762	Kasugamycin hydrochloride Kasumin,盐酸春雷霉素	Antibacterial; Antibiotic; Antifungal	Microbiology/Virology
	Kasugamycin hydrochloride (Kasumin) 是一种能结合 30s 和 70s 核糖体，但不能结合 50s 亚基的抗生素。它模拟 mRNA 核苷酸以破坏 tRNA 结合并抑制经典翻译起始。
T1304	Chlortetracycline hydrochloride Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素	ribosome; Antibacterial; Antibiotic	Microbiology/Virology
	Chlortetracycline hydrochloride (Isphamycin) 是一种特异性钙离子载体抗生素, 抑制氨酰 tRNA 结合到核糖体。
T10582	Borrelidin Treponemycin	Others	Others
	Borrelidin (Treponemycin) is a bacterial and eukaryal threonyl-tRNA synthetase inhibitor. It is a macrolide antibiotic isolated from Streptomyces rochei.
T13304	Virginiamycin S1	Others	Others
	Virginiamycin S1 is a cyclic hexadepsipeptide antibiotic, inhibits bacterial protein synthesis at the level of aminoacyl-tRNA binding and peptide bond formation.
T34765	T6A N-(6-Nebularinylcarbamoyl)threonine,t 6 A,t-6-A,t(6)A,N6-Threonylcarbamoyladenosine	Others	Others
	T6A (N6-Threonylcarbamoyladenosine) 是一种广泛存在具有普遍保守性的核苷，是修饰所必需的化合物。T6A 存在于负责转运 ANN 密码子的 tRNA 中。

天然产物

Oxytetracycline

Cat.No: T0895

Synonym: 土霉素,Terramycin

Target: ribosome, Endogenous Metabolite, Antibacterial, Antibiotic, HSV

Oxytetracycline Dihydrate

Cat.No: T6624

Synonym: 土霉素二水合物,地霉素,Terramycin Dihydrate

Target: Others, Endogenous Metabolite, Antibacterial, Antibiotic, HSV

Spectinomycin dihydrochloride

Cat.No: T0788

Synonym: 淋必治,Spectinomycin 2HCl,盐酸奇霉素,Actinospectacin

Target: ribosome, Antibacterial, Antibiotic

Oxytetracycline Hydrochloride

Cat.No: T21430

Synonym: Biosolvomycin,盐酸土霉素,Oxytetracycline HCl,Oxytetracycline.HCl,Dalimycin,Oxytetracycline, Sodium Salt,Dalinmycin

Target: Antiviral, Endogenous Metabolite, Antibacterial, HSV

Cat.No: T6856

Synonym: 卤夫酮,常山酮,Tempostatin,empostatin,RU-19110

Target: Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

Halofuginone hydrobromide

Cat.No: T3524

Synonym: 卤夫酮溴氢酸盐,Tempostatin,RU-19110 (hydrobromide),Stenorol,常山酮溴酸盐

Target: Others, Calcium Channel, DNA/RNA Synthesis, Sodium Channel, Parasite, TGF-beta/Smad

1-Methylinosine

Cat.No: T19083

Synonym: N1-Methylinosine,Inosine, 1-methyl,1-甲基肌苷

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

5,6-Dihydrouridine

Cat.No: T19146

Target: Endogenous Metabolite

2′-O-Methyluridine

Cat.No: TN7106

Target: Others

Cat.No: T0912L

Synonym: Deschlorobiomycin,Tetracyclinum,Tetracyclin,四环素

Target: Others, ribosome, Antibacterial, Antibiotic

N2-Methylguanosine

Cat.No: T7514

Synonym: 2-甲鳥苷

Target: Nucleoside Antimetabolite/Analog, Endogenous Metabolite

Cat.No: T6447

Synonym: Clinimycin,Sobelin,Chlolincocin,克林霉素

Target: Antibacterial, Antibiotic

N4-Acetylcytidine

Cat.No: T4456

Synonym: N4-乙酰胞苷,N-Acetylcytidine

Target: Others, Endogenous Metabolite

Cat.No: T5055

Synonym: fMet,N-甲酰甲硫氨酸,N-Formyl-L-methionine

Target: Others, Endogenous Metabolite

N6-methyladenosine

Cat.No: T6599

Synonym: N6-甲基腺苷,N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A

Target: Others, Influenza Virus, Endogenous Metabolite

3,5-O-Dicaffeoylquinic acid

Cat.No: TL0005

Synonym: Isochlorogenic Acid A,(-)-3,5-二咖啡酰奎宁酸,(-)-3,5-Dicaffeoyl quinic acid,3,5-Dicaffeoylquinic Acid

Target: Others

Tetracycline hydrochloride

Cat.No: T0912

Synonym: NCI-c55561,盐酸四环素,Tetracycline HCl

Target: ribosome, Antibacterial, Antibiotic

N2,N2-Dimethylguanosine

Cat.No: TQ0193

Synonym: N2,N2-二甲基鸟苷

Target: Endogenous Metabolite

Kasugamycin hydrochloride

Cat.No: T2762

Synonym: Kasumin,盐酸春雷霉素

Target: Antibacterial, Antibiotic, Antifungal

Chlortetracycline hydrochloride

Cat.No: T1304

Synonym: Isphamycin,Chlortetracycline HCl,7-Chlorotetracycline hydrochloride,盐酸金霉素

Target: ribosome, Antibacterial, Antibiotic

Cat.No: T10582

Synonym: Treponemycin

Target: Others

Virginiamycin S1

Cat.No: T13304

Target: Others

Cat.No: T34765

Synonym: N-(6-Nebularinylcarbamoyl)threonine,t 6 A,t-6-A,t(6)A,N6-Threonylcarbamoyladenosine

Target: Others

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