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144

抑制剂 & 化合物

8

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T32907	L-Topaquinone L-Topaquinone residue,2',4',5'-Topaquinone
	L-Topaquinone is a metabolite of dopaquione, an important intermediate in melanogenesis.
T9344	3-Amino-2-oxazolidinone	Others; Endogenous Metabolite	Metabolism; Others
	3-Amino-2-oxazolidinone 是一种呋喃唑烷酮的代谢物 (metabolite)，可用作检测呋喃唑烷酮残留的一个指标。
T8375	ML-210 CID 49766530	Ferroptosis; GPX; Glutathione Peroxidase; Ras	Apoptosis; GPCR/G Protein; MAPK; Metabolism; oxidation-reduction
	ML-210 (CID 49766530) 是一种共价的选择性谷胱甘肽过氧化物酶 4 (GPX4) 抑制剂，EC50为 30 nM。它与 GPX4 硒代半胱氨酸残基结合，具有抗癌活性。
T3088	N-Ethylmaleimide 1-Ethyl-1H-pyrrole-2,5-dione,n-乙基马来酰亚胺,Ethylmaleimide,NEM	Cysteine Protease; DUB	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Proteases/Proteasome; Ubiquitination
	N-Ethylmaleimide (NEM) 是烷基化自由巯基的试剂，是一种半胱氨酸蛋白酶抑制剂，用于实验生化研究。它也是一种去泛素化酶抑制剂，特异性抑制线粒体中的磷酸盐转运。
TP1773L	PGLa acetate	Antibacterial; Antibiotic	Microbiology/Virology
	PGLa acetate 是 magainin 抗生素肽家族的 21 个残基成员。
TP1775L	LL-37, Human acetate(154947-66-7 free base)	Antibacterial	Microbiology/Virology
	LL-37, Human acetate(154947-66-7 free base) 是一种 37 个残基、两亲性、cathelicidin 衍生的抗菌肽，具有广谱的抗菌活性。
TP1365L	Parasin I acetate(219552-69-9 free base)	Antibacterial	Microbiology/Virology
	Parasin I acetate(219552-69-9 free base) 是一种从受伤鲶鱼 (Parasilurus asotus) 的皮肤粘液中分离出来的 19 个残基的强效抗菌肽。
TP1274	3X FLAG peptide
	The 3X FLAG Peptide is a synthetic peptide of 23 amino acid residue. The Asp-Tyr-Lys-Xaa-Xaa-Asp motif is repeated three times in the peptide.
T3175	LDHA-IN-4 AZ 33,AZ-33,LDHA Inhibitor,AZ33	Dehydrogenase	Metabolism
	LDHA-IN-4 (AZ33) 是乳酸脱氢酶 A 选择性抑制剂，IC50=0.5 μM，Kd=0.093 μM。
TP1410	Cecropin A	Antibacterial; Antibiotic	Microbiology/Virology
	Cecropin A 是37个氨基酸组成的线性多肽，表现出抗菌、抗炎和抗肿瘤的功效。
TP1737L	Urotensin II (114-124), human acetate Urotensin II (114-124), human acetate(251293-28-4 free base)	GPR	Endocrinology/Hormones; GPCR/G Protein
	Urotensin II (114-124), human acetate(251293-28-4 free base) 是一种 11 个氨基酸残基肽，是一种有效的血管收缩剂和孤儿受体 GPR14 的激动剂。
T29955	AMC-01 AMC01,AMC 01	Antiviral; PERK	Apoptosis; Immunology/Inflammation
	AMC-01 具有潜在的抗病毒活，可通过丝氨酸残基 51 的磷酸化诱导 eIF2-α 失活，这种作用具有剂量和时间依赖性。AMC-01 可用来研究动脉粥样硬化和帕金森综合征。
T38766L	Histone H3 (1-35) acetate	Others	Others
	Histone H3 (1-35) acetate 是组蛋白 H3 的 35 个残基肽。组蛋白 H3 是一种重要的蛋白质，在基因的动态和长期调控中发挥作用。
TP2057L	Camstatin acetate	NO Synthase	Immunology/Inflammation
	Camstatin acetate 结合钙调蛋白并抑制神经元一氧化氮合酶。它是 PEP-19 的单一钙调蛋白结合 IQ 基序的具有功能活性的 25 个残基片段。
T5146	Eptifibatide acetate (148031-34-9 free base) Eptifibatide acetate,依菲巴特醋酸盐	Others	Others
	Eptifibatide acetate (148031-34-9 free base) (Eptifibatide acetate) 是一种糖蛋白 IIb/IIIa 抑制剂类的抗血小板药物，是一种由 6 个氨基酸和一个巯基丙酰基残基构成的环状七肽。
TP1275	3X FLAG peptide TFA (402750-12-3 free base) 3X FLAG peptide TFA	Others	Others
	3X FLAG peptide TFA (402750-12-3 free base) (3X FLAG peptide TFA) 是一种含有 23 个氨基酸残基的合成肽。 Asp-Tyr-Lys-Xaa-Xaa-Asp 基序在肽中重复了 3 次。
T15735	Leptomycin B CI 940,LMB,来普霉素B	CRM1; Antibiotic; Antifungal	Membrane transporter/Ion channel; Microbiology/Virology
	Leptomycin B (LMB) 是一种抗真菌抗生素，可阻断真核细胞周期，抑制蛋白出核转运。Leptomycin 通过半胱氨酸残基处的共价修饰使 CRM1/exportin 1失活。它
TP1143L	Fibrinopeptide A, human acetate Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate	Others	Others
	Fibrinopeptide A, human acetate (Human fibrinopeptide A acetate)(25422-31-5 free base) 是一种 16 个残基的短多肽，由凝血酶从纤维蛋白原上切割下来。纤维蛋白肽 A (FPA) 由纤维蛋白原蛋白的 N 末端 Aα 区域在被凝血酶切割后产生。
TP1120L	IRBP acetate(211426-18-5 free base) Interphotoreceptor Retinoid Binding Protein Fragment IRBP	Others	Others
	IRBP acetate(211426-18-5 free base) (Interphotoreceptor Retinoid Binding Protein Fragment IRBP) 是一种含有 20 个残基的肽，是一种主要的致病表位。它存在于间质视觉色素结合蛋白肽（IRBP 161-180）的第一个同源重复序列中，可诱导葡萄膜炎后（EAU）。
T1006	Propantheline bromide Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl	AChR	Neuroscience
	Propantheline bromide (Pro-Banthine) 是一种抗毒蕈碱剂，用于研究多汗症，遗尿，胃肠和膀胱痉挛。
T17731L	CL2A-SN-38 DCA 1279680-68-0(free base)	Others	Others
	CL2A-SN-38 DCA 1279680-68-0(free base) 是一种药物-接头偶联物，由有效的 DNA 拓扑异构酶 I 抑制剂 SN-38 和接头 CL2A 组成，用于制造抗体药物偶联物 (ADC)。CL2A-SN-38 由有效的 DNA 拓扑异构酶组成I 抑制剂 SN-38 和接头 CL2A 以制造抗体药物偶联物 (ADC)。 CL2A-SN-38 对一系列人类实体瘤类型提供显着和特异性的抗肿瘤作用。 CL2A 是一种不可切割的复杂 PEG8 和含有三唑的 PABC-肽-mc 接头。 CL2A 可通过 pH 敏感性裂解，产生旁观者效应，并通过二硫键在半胱氨酸残基处结合抗体。
T19178	ACPK	Others	Others
	ACPK is a pyrrolysine analogue bearing an azide residue.
T20933	Bis(p-chlorophenyl)acetic acid Bis(p-chlorphenyl)essigsaeure,Bis(4-chlorophenyl)acetic acid,DDA (degradation product),DDA
	Bis(p-chlorophenyl)acetic acid is a standard for pesticide residue analysis.
TP2475	Kemptamide
	Kemptamide is a synthetic peptide with 13-residue.
T40528	Oxytocin free acid 9-Deamidooxytocin
	Oxytocin free acid, also known as 9-Deamidooxytocin, is an analog of oxytocin where the glycinamide residue at position 9 has been substituted with a glycine residue. Oxytocin, a pleiotropic peptide hormone, has wide-ranging implications for general health, adaptation, development, reproduction, and social behavior.
TP1282	PLP (139-151) PLP 139-151
	PLP (139-151) is amino acid residue residue 139 to 151 of myelin proteolipid protein (PLP). This peptide is used to induce relapsing-remitting (RR)-EAE model.
TP1830	SV40 large T antigen NLS
	SV40 large T antigen NLS is from Large T antigen residue 47 to 55, enables protein import into cell nucleus. This peptide is generated from Large T antigen residue 47 to 55.
T32548	Laminin B1 (1363-1383) Yosh4,Yosh 4,Yosh-4
	Laminin B1 (1363-1383) is the Residue 1363-1383 of the laminin B1 chain.
TP1415	Urotensin II (114-124), human TFA
	Urotensin II (114-124), human TFA, is an 11-amino acid residue peptide with a strong vasoconstrictor effect. This compound acts as an agonist for the orphan receptor GPR14.
T28135	NC043 NC 043,NC-043
	NC043 is an inhibitor of Wnt/β-catenin signaling, it forms a covalent bond with the Cys-516 residue of CARF.
TP2449	Argipressin, ala(10)-
	Argipressin, ala(10)- is a Decapeptide that differs from argipressin in the addition of an N-terminal Ala-residue.
TP1136	Secretin (28-54), human Human secretin
	Secretin (28-54), human, is a 27-amino acid residue peptide with a C-terminal amidation, acting on human secretin receptors.
T69080	T1001
	T1001 is an antagonist of hypoxia-inducible factor-2α subunit (HIF-2α) which displaces residue M252 from inside the HIF-2α PAS-B pocket toward the ARNT subunit to weaken heterodimerization.
TP1737	Urotensin II (114-124), human
	Urotensin II (114-124), human, is an 11-amino acid residue peptide that exhibits strong vasoconstrictor activity and acts as an agonist for the orphan receptor GPR14.
TP1745	Ceratotoxin A
	Ceratotoxin A is a 29-residue peptide extracted from the accessory gland secretion fluid, known for its potent antibacterial properties.
TP1699	SEB Domain (144-153) SEB Domain 144-153
	SEB Domain (144-153) peptide is Staphylococcal Enterotoxin B domain amino acid residue 163-172. SEB Domain (144-153) has been shown to inhibit transcytosis of multiple staphylococcal enterotoxins, SEA, SEE, and TSST-1.
TP1776	HIV-1 TAT 48-60
	HIV-1 TAT (48-60) is a cell-penetrating peptide derived from the human immunodeficient virus (HIV)-1 Tat protein residue 48-60. This is one of the cell-penetrating peptides generated from the human immunodeficient virus -1 Tat protein residue 48-60.
TP1119	Interphotoreceptor retinoid-binding protein(668-687) IRBP(668-687)
	Interphotoreceptor retinoid-binding protein(668-687)is an amino acid residue of human retinoid-binding protein(IRBP) 668-687, which can induce uveitis.
T41204	TAT-Gap19(I130A) TAT-Gap19(I130A)
	TAT-Gap19(I130A) is a control peptide for TAT-Gap19, a Cx43 hemichannel blocker. TAT-Gap19(I130A) consists of TAT-GAP19 with a I130A amino acid residue change at a key residue for GAP19 activity. In C6 glioma cells expression Cx43, TAT-GAP19(1130A) does not inhibit [Ca2+]i-triggered ATP release at 200 μM. TAT-Gap19(I130A) is cell permeable.
T15585	IRBP(668-687) (TFA) Interphotoreceptor retinoid-binding protein(668-687) TFA	Others	Others
	Interphotoreceptor retinoid-binding protein TFA is the amino acid residue 668 to 687 of human interphotoreceptor retinoid-binding protein (IRBP). It also induces uveitis.
T27766	Hymeglusin L659,699,L 659,699,L-659,699
	L-659,699, also known as hymeglusin, is a fungal β-lactone antibiotic that inhibits HMG-CoA synthase (IC50 = 0.12 μM) by covalently modifying the active Cys129 residue of the enzyme.
T31171	D714 D-714,D 714
	D714 is a weakly conserved palm subdomain residue (located far from the catalytic center) that, when replaced by alanine, impains the enzyme's replication in vivo and in vitro.
TP1365	Parasin I
	Parasin I is a potent 19-residue antimicrobial peptide isolated from the skin mucus of wounded catfish (Parasilurus asotus).
T33955	PF-6808472 OX-44,OX44,PF 6808472,OX 44,PF6808472
	PF-6808472 is a cell permeable covalent probe suitable for click chemistry designated to measure kinase selectivity in intact cells. PF-6808472 contains sulfonyl fluoride group, which react with conserved lysine residue within kinase ATP binding site.
TP1142	Fibrinopeptide A, human TFA Human fibrinopeptide A TFA
	Fibrinopeptide A, human is a 16-residue short polypeptide cleaved from fibrinogen by thrombin. Fibrinopeptide A, human locates at the NH2-termini of the Aα chain.The conversion of monomeric fibrinogen into polymeric fibrin is mediated by thrombin, which b
TP1462	MART-1 (26-35) (human) TFA (156251-01-3 free base) MART-1 (26-35) (human) TFA
	MART-1 (26-35) (human) TFA is an amino acid residue of 26-35 protein.
T31218	DBHDA
	DBHDA is a reagent to convert a Cys into a Dha moiety by reacting with a C-terminal Cys residue and thus allowing the use of recombinant Ubl G76C mutants to prepare probes.
TP1830L	SV40 large T antigen NLS acetate	Others	Others
	SV40 large T antigen NLS acetate 是从大 T 抗原残基 47 到 55，使蛋白质进入细胞核。
TP1394	{Val1}-Exendin-3/4
	{Val1}- exendin-3/4 is the first n-terminal 1-28 residue of exendin-4 peptide.
TP1358	Peptide M
	Peptide M is a synthetic Peptide, 50 aa, derived from streptococcus M protein, containing an additional c-terminal cysteine residue.

化合物

Cat.No: T32907

Synonym: L-Topaquinone residue,2',4',5'-Topaquinone

3-Amino-2-oxazolidinone

Cat.No: T9344

Target: Others, Endogenous Metabolite

Cat.No: T8375

Synonym: CID 49766530

Target: Ferroptosis, GPX, Glutathione Peroxidase, Ras

N-Ethylmaleimide

Cat.No: T3088

Synonym: 1-Ethyl-1H-pyrrole-2,5-dione,n-乙基马来酰亚胺,Ethylmaleimide,NEM

Target: Cysteine Protease, DUB

Cat.No: TP1773L

Target: Antibacterial, Antibiotic

LL-37, Human acetate(154947-66-7 free base)

Cat.No: TP1775L

Target: Antibacterial

Parasin I acetate(219552-69-9 free base)

Cat.No: TP1365L

Target: Antibacterial

3X FLAG peptide

Cat.No: TP1274

Cat.No: T3175

Synonym: AZ 33,AZ-33,LDHA Inhibitor,AZ33

Target: Dehydrogenase

Cat.No: TP1410

Target: Antibacterial, Antibiotic

Urotensin II (114-124), human acetate

Cat.No: TP1737L

Synonym: Urotensin II (114-124), human acetate(251293-28-4 free base)

Target: GPR

Cat.No: T29955

Synonym: AMC01,AMC 01

Target: Antiviral, PERK

Histone H3 (1-35) acetate

Cat.No: T38766L

Target: Others

Camstatin acetate

Cat.No: TP2057L

Target: NO Synthase

Eptifibatide acetate (148031-34-9 free base)

Cat.No: T5146

Synonym: Eptifibatide acetate,依菲巴特醋酸盐

Target: Others

3X FLAG peptide TFA (402750-12-3 free base)

Cat.No: TP1275

Synonym: 3X FLAG peptide TFA

Target: Others

Cat.No: T15735

Synonym: CI 940,LMB,来普霉素B

Target: CRM1, Antibiotic, Antifungal

Fibrinopeptide A, human acetate

Cat.No: TP1143L

Synonym: Fibrinopeptide A, human acetate(25422-31-5 free base),Human fibrinopeptide A acetate

Target: Others

IRBP acetate(211426-18-5 free base)

Cat.No: TP1120L

Synonym: Interphotoreceptor Retinoid Binding Protein Fragment IRBP

Target: Others

Propantheline bromide

Cat.No: T1006

Synonym: Neopepulsan,溴丙胺太林,Pro-Banthine,Neometantyl

Target: AChR

CL2A-SN-38 DCA 1279680-68-0(free base)

Cat.No: T17731L

Target: Others

Cat.No: T19178

Target: Others

Bis(p-chlorophenyl)acetic acid

Cat.No: T20933

Synonym: Bis(p-chlorphenyl)essigsaeure,Bis(4-chlorophenyl)acetic acid,DDA (degradation product),DDA

Cat.No: TP2475

Oxytocin free acid

Cat.No: T40528

Synonym: 9-Deamidooxytocin

Cat.No: TP1282

Synonym: PLP 139-151

SV40 large T antigen NLS

Cat.No: TP1830

Laminin B1 (1363-1383)

Cat.No: T32548

Synonym: Yosh4,Yosh 4,Yosh-4

Urotensin II (114-124), human TFA

Cat.No: TP1415

Cat.No: T28135

Synonym: NC 043,NC-043

Argipressin, ala(10)-

Cat.No: TP2449

Secretin (28-54), human

Cat.No: TP1136

Synonym: Human secretin

Cat.No: T69080

Urotensin II (114-124), human

Cat.No: TP1737

Cat.No: TP1745

SEB Domain (144-153)

Cat.No: TP1699

Synonym: SEB Domain 144-153

HIV-1 TAT 48-60

Cat.No: TP1776

Interphotoreceptor retinoid-binding protein(668-687)

Cat.No: TP1119

Synonym: IRBP(668-687)

TAT-Gap19(I130A)

Cat.No: T41204

Synonym: TAT-Gap19(I130A)

IRBP(668-687) (TFA)

Cat.No: T15585

Synonym: Interphotoreceptor retinoid-binding protein(668-687) TFA

Target: Others

Cat.No: T27766

Synonym: L659,699,L 659,699,L-659,699

Cat.No: T31171

Synonym: D-714,D 714

Cat.No: TP1365

Cat.No: T33955

Synonym: OX-44,OX44,PF 6808472,OX 44,PF6808472

Fibrinopeptide A, human TFA

Cat.No: TP1142

Synonym: Human fibrinopeptide A TFA

MART-1 (26-35) (human) TFA (156251-01-3 free base)

Cat.No: TP1462

Synonym: MART-1 (26-35) (human) TFA

Cat.No: T31218

SV40 large T antigen NLS acetate

Cat.No: TP1830L

Target: Others

{Val1}-Exendin-3/4

Cat.No: TP1394

Cat.No: TP1358

Cat. No.	Product Name	Target	Signaling Pathways
T4741	N-Formylglycine	Others; Endogenous Metabolite	Metabolism; Others
	N-Formylglycine 是内源性代谢产物的一种。
T13482	2'-O-Methyladenosine	Endogenous Metabolite	Metabolism
	2'-O-Methyladenosine 是甲基化腺嘌呤的残基，在正常人群和腺苷脱氨基酶缺乏病人的尿液中均可被检测到。它显示出独特的降血压活性。
T67867	Mycaminosyltylonolide	Antibacterial	Microbiology/Virology
	Mycaminosyltylonolide 是一种大环内酯类抗生素，它是 tyololide 在位置5上具有β - d -mycaminosyl 残基。Mycaminosyltylonolide 是一种有效的抗生素，具有抗菌活性和抑制荧光素酶的合成。
T5055	For-Met-OH fMet,N-甲酰甲硫氨酸,N-Formyl-L-methionine	Others; Endogenous Metabolite	Metabolism; Others
	For-Met-OH (N-Formyl-L-methionine) 是内源性代谢产物的一种。
T6599	N6-methyladenosine N6-甲基腺苷,N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A	Others; Influenza Virus; Endogenous Metabolite	Metabolism; Microbiology/Virology; Others
	N6-methyladenosine (NSC-29409) 是甲基化的腺嘌呤残基，苷是转移核糖核酸降解的内源性尿核苷产物。它是存在于所有高等真核生物中普遍的的信使 RNA 内部修饰，可修饰病毒 RNA，有抗病毒活性。
T83341	3α,4β-Galactotriose
	3α,4β-Galactotriose为一种半乳糖类化合物。
T75974	Cecropin A TFA
	Cecropin A TFA 是由 37 个氨基酸残基构成的线性抗菌肽，从 Hyalaphora cecropiapupae 得到，具有抗菌、抗炎和抗癌作用。
T82032	Isoglobotriaose Gala-3Galb-4Glc
	Isoglobotriaose (Gala-3Galb-4Glc)是哺乳动物组织中的一种糖鞘脂，属于球状三脂糖的类似物。其神经节苷脂衍生物isoglobotriaosylceramide特定分布于小肠非上皮细胞的残基中，而globotriaosylceramide则在两种细胞隔室中都有分布。

天然产物

N-Formylglycine

Cat.No: T4741

Target: Others, Endogenous Metabolite

2'-O-Methyladenosine

Cat.No: T13482

Target: Endogenous Metabolite

Mycaminosyltylonolide

Cat.No: T67867

Target: Antibacterial

Cat.No: T5055

Synonym: fMet,N-甲酰甲硫氨酸,N-Formyl-L-methionine

Target: Others, Endogenous Metabolite

N6-methyladenosine

Cat.No: T6599

Synonym: N6-甲基腺苷,N-Methyladenosine,6-Methyladenosine,NSC-29409,m6A

Target: Others, Influenza Virus, Endogenous Metabolite

3α,4β-Galactotriose

Cat.No: T83341

Cat.No: T75974

Isoglobotriaose

Cat.No: T82032

Synonym: Gala-3Galb-4Glc

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