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98

抑制剂 & 化合物

6

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T20543	Flurochloridone 氟咯草酮,R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401	Apoptosis; Reactive Oxygen Species	Apoptosis; Immunology/Inflammation; Metabolism; NF-κB
	Flurochloridone (R 40244) 是一种选择性除草剂。 Flurochloridone 诱导细胞凋亡并受线粒体功能障碍和氧化应激的调节。
T20573	Carbetamide Legurame,卡草胺,EPA Pesticide Chemical Code 259200,Carbetamid,11,561 RP,Carbetamex,Caswell No. 159B	Others	Others
	Carbetamide (Caswell No. 159B) 是一种除草剂，在土壤中具有良好的流动性。
T41244	Triticonazole	Antifungal	Microbiology/Virology
	Triticonazole 是一种三唑类农药。它具有杀菌和干扰内分泌作用。
T20669	Bentazone 苯达松,BAS 351-07H,EPA Pesticide Chemical Code 275200
	Paicaotan is a heterocyclic herbicide. It can removal broadleaf weeds and sedge in the soybean field.
T39849	Propargite	Parasite	Microbiology/Virology
	Propropgite 通过诱导 DNA 损伤来诱导 β 细胞坏死。它诱导 MIN6 细胞死亡的 IC50为 1 μM.。它可用于杀死螨虫。
T29000	Tralomethrin EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout
	Tralomethrin is used as a pyrethroid insecticide. It modifies the gating kinetics of the sodium channels in neurons, increases the length of time the channel remains open after a stimulus, thereby depolarizing the neuron for a longer period of time. This leads to uncontrolled spasms, paralysis, and eventual death.
T24172	Iodofenphos NSC-190998,EPA Pesticide Chemical Code 309700,Nuvanol N,NSC190998,NSC 190998
	Iodofenphos is an obsolete insecticide.
T23768	Azothoate Caswell No. 206A,L 1058,L-1058,EPA Pesticide Chemical Code 206100,L1058
	Azothoate is an insecticide agent.
T29981	Amidochlor Caswell No. 005B,EPA Pesticide Chemical Code 128001,MON 4620,MON 4621,Limit
	Amidochlor is a growth regulator.
T8383	Cyclopentolate Hydrochloride	AChR	Neuroscience
	Cyclopentolate Hydrochloride 是一种阿托品样毒蕈碱受体拮抗剂，是眼科常用的抗毒蕈碱剂，对睫状肌毒蕈碱受体的 pKB 值为 7.8。
T27794	λ-Cyhalothrin lambda-Cyhalothrin,Karate,λ-氯氟氰菊酯,Icon	Sodium Channel; Parasite	Membrane transporter/Ion channel; Microbiology/Virology
	λ-Cyhalothrin (Icon) 是广谱的 II 型合成除虫菊酯杀虫剂，含有 α-氰基，用于防治多种害虫。它是一种钠通道神经毒素，靶向中枢神经系统中神经元膜。
T40656	Chlorobenzuron	Others	Others
	Chlorobenzuron 是一种有效的几丁质合成酶抑制剂，具有杀虫的活性，可以抑制幼虫发育和蛹化的作用。
T20539	Pirimiphos-methyl R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic	AChE; Parasite	Microbiology/Virology; Neuroscience
	Pirimiphos-methyl (AI3-27699) 是一种速效有机磷杀虫剂和杀螨剂，对目标生物的乙酰胆碱酯酶有抑制作用。甲基嘧啶磷常用于农粮贮藏过程中甲虫、鼻甲虫、飞蛾和蝽蛄的防治。
T69692	BRD-K25923209
	BRD-K25923209 is a novel inhibitor of BAF transcriptional repression.
T14954	Chlorthal-dimethyl Dimethyl tetrachloroterephthalate	Others	Others
	Chlorthal-dimethyl (Dimethyl tetrachloroterephthalate) 用作农药中间体。
T0574	Diphenyl sulfide 二苯硫醚,Phenyl sulfide	Others	Others
	Diphenyl sulfide (Phenyl sulfide) 用作农药、医药、染料的中间体
T7867	Flutriafol	NMDAR; Antifungal	Microbiology/Virology; Neuroscience
	Flutriafol 是一种三唑类广谱杀菌试剂。
T4384	Halofenozide	Others	Others
	Halofenozide 是一种新的昆虫生长调节剂 (IGR)，具有苯甲酰肼结构，也是一种蜕皮激素 (ecdysteroid) 激动剂。可模拟天然昆虫蜕皮激素 20-羟基蜕皮激素的作用，
T0528	4-Fluoroanisole	Others	Others
	4-Fluoroanisole 是医药、农药、液晶材料的中间体。
T7431	1,4-Dichlorobenzene 1,4-二氯苯,p-Dichlorobenzene,para-dichlorobenzene	Others	Others
	1,4-Dichlorobenzene (p-Dichlorobenzene) 是一种防蛀剂，也可用作生产颜料和杀虫剂及消毒剂等的中间体。
T3493	Clofentezine Bisclofentazin,Acaristop,Apollo,四螨嗪	Others	Others
	Clofentezine (Apollo) 是生长抑制剂，对螨虫具有显著的致死作用。
T7440	p,p'-DDE p,p'-dichlorodiphenyldichloroethylene,4,4'-DDE,Dichlorodiphenyldichloroethylene,2，2-双（4-氯苯基）-1，1-二氯乙烯	Androgen Receptor; Drug Metabolite	Endocrinology/Hormones; Metabolism
	p,p'-DDE (p,p'-dichlorodiphenyldichloroethylene) 是持久性 DDT 的主要代谢物。4,4'-DDE 是一种有效的雄激素受体拮抗剂，IC50=5 μM，Ki=3.5 μM。
T5116	Iprodione	Others; Reactive Oxygen Species; Antifungal	Immunology/Inflammation; Metabolism; Microbiology/Virology; NF-κB; Others
	Iprodione 是一种二甲酰亚胺类的高度特异性杀菌剂，能通过产生自由氧自由基引起氧化损伤。
T0567	2-Amino-5-chlorobenzoic acid	Others; Amino Acids and Derivatives	Metabolism; Others
	2-Amino-5-chlorobenzoic acid 是杀虫剂 Chlordimeform 的代谢物。可用于制备缓解疾病的抗风湿药（DMARDs）。
T16044	Methoprene 烯虫酯,ZR-515	Others	Others
	Methoprene (ZR-515) 是一种保幼激素模拟物和一种生物杀虫剂。Methoprene 作为昆虫生长调节剂，干扰昆虫的生命周期并阻止其成熟或繁殖。
T20110	Ethylene thiourea ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲	Others	Others
	Ethylene thiourea (NCIC03372) 是一种用于水果和蔬菜生产的农药。它还用作基于质子化学交换依赖性饱和转移的 MRI 研究的新型造影剂。
T19739	Simazine Tafazine,Aquazine,Radocon,Herbex,西玛津	Others	Others
	Simazine (Tafazine) 是三嗪类除草剂，普遍用于农业、盆栽植物和树木的生产。它具有植物毒性，但对土壤微生物和藻类毒性较低。
T4055	Etoxazole	Others	Others
	Etoxazole 是一种杀螨剂/杀虫剂，通过抑制几丁质生物合成来控制螨虫。用作农药检测的标准。
T72049	4-N-Nonyloxyphenol 4-nonoxyphenol,p-Nonyloxyphenol
	4-N-Nonyloxyphenol (4-nonoxyphenol) 是一种基于高岭土纳米管的杂化光敏剂，是一种广泛使用的农药和内分泌干扰剂，可用于苯酚基农药的光降解。
T5627	Methoxychlor	Others	Others
	Methoxychlor 是一种有机氯农药，被认为是一种内分泌干扰物，会影响不同细胞模型中的 Ca²⁺ 稳态和细胞活力。
T0404	8-Hydroxyquinoline Hydroxyquinoline,8-Quinolinol,羟基喹啉,Oxine,8-羟基喹啉,8-Oxychinolin	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	8-Hydroxyquinoline (8-Quinolinol) 是单质子二齿螯合剂, 也是转录抑制剂，防腐剂，消毒剂和杀虫剂。
T19735	Flucycloxuron 氟螨脲,(E)-flucycloxuron,Andalin	Others	Others
	Flucycloxuron ((E)-flucycloxuron) 是一种甲壳素合成抑制剂，用作杀虫剂。在昆虫模型中，该抑制剂已被证明会影响几种生殖事件，例如产卵前的持续时间。
T19084	1-Naphthyl acetate	AChE	Neuroscience
	1-Naphthyl acetate 是一种有吸引力的生色底物，用于检测红细胞乙酰胆碱酯酶的活性。它具有检测有机磷农药中毒的潜力。
T19859	Nicosulfuron Milagro,Accent,Motivell,烟嘧磺隆	Others	Others
	Nicosulfuron (Milagro) 是一种磺酰脲类的选择性除草剂，常用作出苗后的除草剂，保护玉米作物免受杂草的侵害。它也能够降低乙酰乳酸合酶的活性。
T20595	Propiconazole CGA64250,CGA-64250,CGA 64250,Desmel
	Propiconazole is an agricultural pesticide.
T24248	Karetazan Ciobutide
	Karetazan is a pesticide agent.
T24249	Karsil Niagara-4562,Niagara 4562,Erlujixiancaoan,Niagara4562
	Karsil is an agricultural pesticide.
T25988	Proclonol R 8284,R-8284,Kilacar,R8284
	Proclonol is used as a pesticide.
T26006	Pyrolan NSC404297,NSC 404297,NSC-404297
	Pyrolan is used as a pesticide.
T24999	Acequinocyl AI3-29615,AI3 29615,AI329615
	Acequinocyl is used as a pesticide.
T24179	Isocil Hyvar,Herbicide 82
	Isocil is a pesticide.
T25008	AI3-15089 NSC5807,NSC 5807,NSC-5807
	AI3-15089 is used as an Experimental Pesticide.
T26125	Rovicurt Permethrin-tetramethrin mixt.
	Rovicurt is use as a pesticide.
T20249	Fenothiocarb Phenothiocarb,KCO-3001,Panocon
	Fenothiocarb is an agent of pesticide.
T27137	Decarbofuran Bayer 62863
	Decarbofuran is a carbamate pesticide.
T25138	Barthrin
	Barthrin is used as an Experimental Pesticide.
T23691	AI 3-25706 AI-3-25706,AI3-25706
	AI 3-25706 is a pesticide.
T31486	Dimethachlor Teridox
	Dimethachlor is a pesticide and herbicide used in wetland areas.
T23690	AI 3-25614 AI-3-25614,AI3-25614
	AI 3-25614 is a pesticide.
T20219	Bioresmethrin Penick-1390,Bioresmetrina,Penick 1390,Penick1390
	Bioresmethrin is a pesticide of synthetic pyrethroid.

化合物

Flurochloridone

Cat.No: T20543

Synonym: 氟咯草酮,R 40244,R-40244,R40244,EPA Pesticide Chemical Code 128401

Target: Apoptosis, Reactive Oxygen Species

Cat.No: T20573

Synonym: Legurame,卡草胺,EPA Pesticide Chemical Code 259200,Carbetamid,11,561 RP,Carbetamex,Caswell No. 159B

Target: Others

Cat.No: T41244

Target: Antifungal

Cat.No: T20669

Synonym: 苯达松,BAS 351-07H,EPA Pesticide Chemical Code 275200

Cat.No: T39849

Target: Parasite

Cat.No: T29000

Synonym: EPA Pesticide Chemical Code 121501,SAGA,HAG-107,HAG 107,Scout

Cat.No: T24172

Synonym: NSC-190998,EPA Pesticide Chemical Code 309700,Nuvanol N,NSC190998,NSC 190998

Cat.No: T23768

Synonym: Caswell No. 206A,L 1058,L-1058,EPA Pesticide Chemical Code 206100,L1058

Cat.No: T29981

Synonym: Caswell No. 005B,EPA Pesticide Chemical Code 128001,MON 4620,MON 4621,Limit

Cyclopentolate Hydrochloride

Cat.No: T8383

Target: AChR

Cat.No: T27794

Synonym: lambda-Cyhalothrin,Karate,λ-氯氟氰菊酯,Icon

Target: Sodium Channel, Parasite

Cat.No: T40656

Target: Others

Pirimiphos-methyl

Cat.No: T20539

Synonym: R 33986,甲基嘧啶磷,AI3-27699,Caswell No. 334B,PP511,Actelic

Target: AChE, Parasite

Cat.No: T69692

Chlorthal-dimethyl

Cat.No: T14954

Synonym: Dimethyl tetrachloroterephthalate

Target: Others

Diphenyl sulfide

Cat.No: T0574

Synonym: 二苯硫醚,Phenyl sulfide

Target: Others

Cat.No: T7867

Target: NMDAR, Antifungal

Cat.No: T4384

Target: Others

4-Fluoroanisole

Cat.No: T0528

Target: Others

1,4-Dichlorobenzene

Cat.No: T7431

Synonym: 1,4-二氯苯,p-Dichlorobenzene,para-dichlorobenzene

Target: Others

Cat.No: T3493

Synonym: Bisclofentazin,Acaristop,Apollo,四螨嗪

Target: Others

Cat.No: T7440

Synonym: p,p'-dichlorodiphenyldichloroethylene,4,4'-DDE,Dichlorodiphenyldichloroethylene,2，2-双（4-氯苯基）-1，1-二氯乙烯

Target: Androgen Receptor, Drug Metabolite

Cat.No: T5116

Target: Others, Reactive Oxygen Species, Antifungal

2-Amino-5-chlorobenzoic acid

Cat.No: T0567

Target: Others, Amino Acids and Derivatives

Cat.No: T16044

Synonym: 烯虫酯,ZR-515

Target: Others

Ethylene thiourea

Cat.No: T20110

Synonym: ETU,Imidazolidinethione,NCI C03372,NCIC03372,NCI-C03372,亚乙基硫脲

Target: Others

Cat.No: T19739

Synonym: Tafazine,Aquazine,Radocon,Herbex,西玛津

Target: Others

Cat.No: T4055

Target: Others

4-N-Nonyloxyphenol

Cat.No: T72049

Synonym: 4-nonoxyphenol,p-Nonyloxyphenol

Cat.No: T5627

Target: Others

8-Hydroxyquinoline

Cat.No: T0404

Synonym: Hydroxyquinoline,8-Quinolinol,羟基喹啉,Oxine,8-羟基喹啉,8-Oxychinolin

Target: Others, Antibacterial, Antibiotic

Cat.No: T19735

Synonym: 氟螨脲,(E)-flucycloxuron,Andalin

Target: Others

1-Naphthyl acetate

Cat.No: T19084

Target: AChE

Cat.No: T19859

Synonym: Milagro,Accent,Motivell,烟嘧磺隆

Target: Others

Cat.No: T20595

Synonym: CGA64250,CGA-64250,CGA 64250,Desmel

Cat.No: T24248

Synonym: Ciobutide

Cat.No: T24249

Synonym: Niagara-4562,Niagara 4562,Erlujixiancaoan,Niagara4562

Cat.No: T25988

Synonym: R 8284,R-8284,Kilacar,R8284

Cat.No: T26006

Synonym: NSC404297,NSC 404297,NSC-404297

Cat.No: T24999

Synonym: AI3-29615,AI3 29615,AI329615

Cat.No: T24179

Synonym: Hyvar,Herbicide 82

Cat.No: T25008

Synonym: NSC5807,NSC 5807,NSC-5807

Cat.No: T26125

Synonym: Permethrin-tetramethrin mixt.

Cat.No: T20249

Synonym: Phenothiocarb,KCO-3001,Panocon

Cat.No: T27137

Synonym: Bayer 62863

Cat.No: T25138

Cat.No: T23691

Synonym: AI-3-25706,AI3-25706

Cat.No: T31486

Synonym: Teridox

Cat.No: T23690

Synonym: AI-3-25614,AI3-25614

Cat.No: T20219

Synonym: Penick-1390,Bioresmetrina,Penick 1390,Penick1390

Cat. No.	Product Name	Target	Signaling Pathways
TN2132	Quinizarin 1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌	Others; DNA/RNA Synthesis; Antifungal	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; Microbiology/Virology; Others
	Quinizarin (1,4-Dihydroxyanthraquinone) 是一种杀菌剂和杀虫剂，可抑制肿瘤细胞生长。
T0051	Urethane Ethyl carbamate,Ethylurethane,Carbamic acid ethyl ester,氨基甲酸乙酯	Chloride channel; GABA Receptor; Antibacterial; GluR; NMDAR; AChR; Parasite	Membrane transporter/Ion channel; Microbiology/Virology; Neuroscience
	Urethane (Ethylurethane) 是多种食品中发酵形成的副产物，是氨基甲酸的乙酯，具有抑制细菌、海胆卵、原生动物和植物组织生长的作用。
T0311	Salicyl alcohol α,2-Toluenediol,o-Methylolphenol,2-Hydroxybenzyl alcohol,水杨醇,邻羟基苄醇,Saligenin,Saligenol,Diathesin	Others	Others
	Salicyl alcohol (2-Hydroxybenzyl alcohol) 是一种医药、香料、农药的合成中间体。
T40712	Diethyl fumarate	Others	Others
	Diethyl fumarate 是农药马拉硫磷的分解产物。 Diethyl fumarate 会在皮肤上引起非免疫性接触性荨麻疹。
T16042	Metaldehyde	BCL	Apoptosis
	Metaldehyde is used for snails and other gastropods pesticide against.
T36828	9(Z)-Tricosene
	(9Z)-Tricosene is a pheromone released by insects, including D. melanogaster, M. domestica (house fly), and A. mellifera L. (honey bee). In Drosophila, it induces aggregation behavior and is an oviposition guidance cue for females. Due to its aggregation-inducing activity, it is used as a bait pesticide to attract insects to traps. The mechanism of action in Drosophila is the activation of antennal basiconic Or7a receptors. It is also highly produced by honey bees during the waggle dance, which ...

天然产物

Cat.No: TN2132

Synonym: 1,4-Dihydroxyanthraquinone,1,4-二羟基蒽醌

Target: Others, DNA/RNA Synthesis, Antifungal

Cat.No: T0051

Synonym: Ethyl carbamate,Ethylurethane,Carbamic acid ethyl ester,氨基甲酸乙酯

Target: Chloride channel, GABA Receptor, Antibacterial, GluR, NMDAR, AChR, Parasite

Salicyl alcohol

Cat.No: T0311

Synonym: α,2-Toluenediol,o-Methylolphenol,2-Hydroxybenzyl alcohol,水杨醇,邻羟基苄醇,Saligenin,Saligenol,Diathesin

Target: Others

Diethyl fumarate

Cat.No: T40712

Target: Others

Cat.No: T16042

Target: BCL

Cat.No: T36828

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