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Cat. No.	Product Name	Target	Signaling Pathways
T39429	AHN 1-055 hydrochloride 3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	AHN 1-055 hydrochloride (3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride) 与多巴胺转运蛋白具有高亲和力，是多巴胺摄取抑制剂，IC50为 71 nM。
T8702	SKF-83566	Dopamine Receptor; 5-HT Receptor; AChR	GPCR/G Protein; Neuroscience
	SKF-83566 是一种具有血脑渗透性和口服活性的 D1 样多巴胺受体拮抗剂和一种较弱的竞争性 5-HT2 受体拮抗剂，Ki 为 11 nM。它是竞争性多巴胺转运蛋白抑制剂，可用于研究帕金森氏症和对尼古丁渴望的缓解的相关研究。
T1233	Oxolinic acid Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox	Dopamine Receptor; DNA/RNA Synthesis; Antibacterial; Antibiotic	Cell Cycle/Checkpoint; DNA Damage/DNA Repair; GPCR/G Protein; Microbiology/Virology; Neuroscience
	Oxolinic acid (Nidantin) 是一种抗生素，对革兰氏阴性菌和革兰氏阳性菌均有效，可研究急性和慢性尿路感染。它是一种 DNA/RNA 合成抑制剂，也是一种多巴胺摄取抑制剂，能刺激小鼠的活跃过度。
T0031L	Ziprasidone hydrochloride 盐酸齐拉西酮,齐拉西酮盐酸盐,CP-88059 hydrochloride,CP-88059,Ziprasidone HCl	Dopamine Receptor; 5-HT Receptor; Adrenergic Receptor; Norepinephrine; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Ziprasidone hydrochloride (CP-88059 hydrochloride) 是一种联合 5-HT（5-羟色胺）和多巴胺受体拮抗剂，具有抗精神病活性的强效作用。它也是去甲肾上腺素再摄取抑制剂。
T7341	Diclofensine Ro 8-4650,(+/-)-双氮奋兴	Dopamine Receptor; Monoamine Transporter	GPCR/G Protein; Membrane transporter/Ion channel; Neuroscience
	Diclofensine (Ro 8-4650) 是一种高效单胺再摄取抑制剂，在大鼠脑突触体中能够阻断多巴胺 (IC50=0.74 nM)、去甲肾上腺素 (IC50=2.3 nM) 和 5-羟色胺 (IC50=3.7 nM)。
T22508	3-CPMT Chlortropbenzyl hydrochloride,3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride,SL6057,Wy 2149,FC-1	Dopamine Receptor	GPCR/G Protein; Neuroscience
	3-CPMT (FC-1) 是一种多巴胺摄取抑制剂和一种有效的长效抗组胺剂。
T19337	GBR 12783 dihydrochloride GBR12783 2HCl	Others	Others
	GBR 12783 dihydrochloride (GBR12783 2HCl) 是一种特异性，有效且选择性的多巴胺摄取抑制剂，可抑制大鼠和小鼠纹状体突触小体对 [3H] 多巴胺 ([3H]dopamine) 的摄取，IC50值分别为 1.8 nM 和 1.2 nM。GBR 12783 dihydrochloride 还可改善大鼠记忆力并增加海马通路乙酰胆碱的释放。
T23234	Rimcazole dihydrochloride	Others	Others
	Rimcazole dihydrochloride 是 Rimcazole 的盐酸盐，是一种σ受体拮抗剂。Rimcazole dihydrochloride 还与多巴胺转运蛋白结合，抑制多巴胺的摄取。
T7070	Nomifensine maleate Nomifensine (maleate),诺米芬新马来酸盐,(±)-Nomifensine maleat	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Nomifensine maleate (Nomifensine (maleate)) 是一种多巴胺摄取的选择性抑制剂，可用于成人注意力缺陷障碍的研究。
T1568	Amoxapine 阿莫沙平,CL-67772	GlyT	Neuroscience
	Amoxapine (CL-67772) 是一种dibenzoxazepine 家族的四环抗抑郁药，常被归类为仲胺三环类抗抑郁药。
T1336	Benztropine mesylate Benzotropine mesylate,苯扎托品,Benzatropine mesylate,Benztropine methanesulfonate,甲磺酸苯扎托品	Dopamine Receptor; AChR; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Benztropine mesylate (Benztropine methanesulfonate) 是一种可口服的中枢性抗胆碱能剂，用于帕金森氏病的研究。它是抗组胺剂，抑制多巴胺的吸收。它也是人 D2多巴胺受体的变构拮抗剂，具有抗癌症干细胞的作用。
T41194	FFN 102 mesylate	Others	Others
	FFN 102 mesylate 是pH 响应型荧光假神经递质(FFN)，作为选择性多巴胺转运蛋白(DAT)和VMAT2底物。FFN 102 mesylate 与38个中枢神经系统受体(包括多巴胺和血清素受体)无明显结合。它的Ex-max在pH 值5时为340 nm，在pH 值7.5时为370 nm，在pH 值为5和7.5时，Em-max为435 nm。
T68070	Fezolamine	Norepinephrine	Neuroscience
	Fezolamine 是一种新型可口服的非三环类化合物，具有抗抑郁活性。它在体外阻断[3H]去甲肾上腺素的突触体摄取方面的选择性是摄取[4H]3-羟色胺或[3H]多巴胺的3至2倍。在使用单胺耗尽动物的经典行为测试中，它阻止了利血平和四苯的抑制作用。
T7153	Vanoxerine dihydrochloride GBR-12909 dihydrochloride,伐诺司林二盐酸盐,I893 dihydrochloride	Dopamine Receptor	GPCR/G Protein; Neuroscience
	Vanoxerine dihydrochloride (GBR-12909 dihydrochloride) 是一种竞争性的、有效的、选择性的多巴胺再摄取抑制剂，能够与多巴胺转运体 (DAT) 上的靶点结合。
T22799	GBR 13069 dihydrochloride	Others	Others
	GBR 13069 dihydrochloride is a dopamine uptake inhibitor.
T24712	Rimcazole
	Rimcazole is a sigma receptor antagonist. It also binds to the dopamine transporter and inhibiting dopamine uptake.
T71528	MCN-5908
	MCN-5908 is a dopamine uptake inhibitor.
T23718	Amfonelic Acid
	Amfonelic Acid is a dopamine uptake blocker.
T22877	JHW 007 hydrochloride	Others	Others
	JHW 007 hydrochloride is a Dopamine uptake inhibitor.
T24645	Piroheptine HCl Piroheptine Hydrochloride,Trimol
	Piroheptine HCl is an agent of anticholinergic that acts by inhibiting dopamine uptake and completely preventing loss of striatal dopamine in MPTP-treated mice.
T68727	GBR-13119
	GBR-13119 is a dopamine uptake inhibitor.
T68709	GBR-13098 dimethanesulfonate
	GBR-13098 dimethanesulfonate is an inhibitor of dopamine uptake.
T11371	GBR 12783	Others	Others
	GBR 12783 can improve memory performance and increase hippocampal acetylcholine release in rats. GBR 12783 is a specific, potent and selective dopamine uptake inhibitor that inhibits the [3H]dopamine uptake by rat and mice striatal synaptosomes with IC50s of 1.8 nM and 1.2 nM, respectively.
T23781	Benzatropine Akitan,Benztropine,NK 02,Cogentinol,Cogentine
	Benzatropine is a centrally active muscarinic antagonist. It also inhibits the uptake of dopamine. It has been used in the symptomatic treatment of Parkinson's Disease.
T28349	PD-89211 PD89211
	PD 89211 is a selective dopamine D4 receptor antagonist with high selectivity for the DA D4.2 receptor (> 800-fold) as compared to other hDA receptor subtypes, rat brain serotonin, and adrenergic receptors. In vitro, PD 89211 reverses quinpirole-induced [
T27689	JNJ-7925476 HCl JNJ-7925476,JNJ7925476,JNJ 7925476
	JNJ-7925476 HCl is a triple monoamine uptake inhibitor. JNJ-7925476 Salt blocks the dopamine transporter (DAT), norepinephrine transporter (NET) and serotonin transporter (SERT) in the central nervous system. The ED(50) values for JNJ-7925476 occupancy of
T37699	Org 24598
	Potent and selective inhibitor of the glial glycine transporter GlyT1b (IC50 = 6.9 nM). Displays negligible activity at GlyT-2, adrenoreceptors, dopamine, 5HT receptors and noradrenaline, dopamine, 5HT and GABA transporters (pIC50 in vivo. Chue et al (2013) Glycine reuptake inhibition as a new therapeutic approach in schizophrenia: focus on the glycine transporter 1 (GlyT1). Curr.Pharm.Des. 19 1311 PMID:23194655 \|Brown et al (2001) Discovery and SAR of org 24598-a selective glycine uptake inhibi...
T62008	Mazaticol
	Mazaticol 是一种抗胆碱剂，可以阻断毒蕈碱乙酰胆碱受体和胆碱能神经活动。Mazaticol 是有效的 3H-QNB 和 3H-PZ 结合抑制剂，对 M2 受体具有高亲和力。Mazaticol 抑制纹状神经末梢的多巴胺摄取。Mazaticol 在帕金森综合征种有研究价值。

化合物

AHN 1-055 hydrochloride

Cat.No: T39429

Synonym: 3α-Bis-(4-fluorophenyl) Methoxytropane hydrochloride

Target: Dopamine Receptor

Cat.No: T8702

Target: Dopamine Receptor, 5-HT Receptor, AChR

Cat.No: T1233

Synonym: Emyrenil,Nidantin,NSC 110364,恶喹酸,Dioxacin,Urinox

Target: Dopamine Receptor, DNA/RNA Synthesis, Antibacterial, Antibiotic

Ziprasidone hydrochloride

Cat.No: T0031L

Synonym: 盐酸齐拉西酮,齐拉西酮盐酸盐,CP-88059 hydrochloride,CP-88059,Ziprasidone HCl

Target: Dopamine Receptor, 5-HT Receptor, Adrenergic Receptor, Norepinephrine, Histamine Receptor

Cat.No: T7341

Synonym: Ro 8-4650,(+/-)-双氮奋兴

Target: Dopamine Receptor, Monoamine Transporter

Cat.No: T22508

Synonym: Chlortropbenzyl hydrochloride,3-[(4-chlorophenyl)-phenylmethoxy]-8-methyl-8-azabicyclo[3.2.1]octane hydrochloride,SL6057,Wy 2149,FC-1

Target: Dopamine Receptor

GBR 12783 dihydrochloride

Cat.No: T19337

Synonym: GBR12783 2HCl

Target: Others

Rimcazole dihydrochloride

Cat.No: T23234

Target: Others

Nomifensine maleate

Cat.No: T7070

Synonym: Nomifensine (maleate),诺米芬新马来酸盐,(±)-Nomifensine maleat

Target: Dopamine Receptor

Cat.No: T1568

Synonym: 阿莫沙平,CL-67772

Target: GlyT

Benztropine mesylate

Cat.No: T1336

Synonym: Benzotropine mesylate,苯扎托品,Benzatropine mesylate,Benztropine methanesulfonate,甲磺酸苯扎托品

Target: Dopamine Receptor, AChR, Histamine Receptor

FFN 102 mesylate

Cat.No: T41194

Target: Others

Cat.No: T68070

Target: Norepinephrine

Vanoxerine dihydrochloride

Cat.No: T7153

Synonym: GBR-12909 dihydrochloride,伐诺司林二盐酸盐,I893 dihydrochloride

Target: Dopamine Receptor

GBR 13069 dihydrochloride

Cat.No: T22799

Target: Others

Cat.No: T24712

Cat.No: T71528

Cat.No: T23718

JHW 007 hydrochloride

Cat.No: T22877

Target: Others

Piroheptine HCl

Cat.No: T24645

Synonym: Piroheptine Hydrochloride,Trimol

Cat.No: T68727

GBR-13098 dimethanesulfonate

Cat.No: T68709

Cat.No: T11371

Target: Others

Cat.No: T23781

Synonym: Akitan,Benztropine,NK 02,Cogentinol,Cogentine

Cat.No: T28349

Synonym: PD89211

JNJ-7925476 HCl

Cat.No: T27689

Synonym: JNJ-7925476,JNJ7925476,JNJ 7925476

Cat.No: T37699

Cat.No: T62008

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