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Search Results for " cell stabilizer "

18

抑制剂 & 化合物

2

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T8239	Cromoglicic acid	Others	Others
	Cromoglicic acid 可防止肥大细胞释放炎性化学物质，例如组胺。
T0211	Azelastine Azelastina,Astelin,Azelastinum,氮卓斯汀	SARS-CoV; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Microbiology/Virology; Neuroscience
	Azelastine (Azelastinum) 是一种选择性组胺 1 拮抗剂，可研究过敏性鼻炎、哮喘、糖尿病高脂血症和 SARS-CoV-2 。
T4566	Lodoxamide Lodoxamidum,洛草氨酸	GPR; Histamine Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Lodoxamide (Lodoxamidum) 是一种抗过敏药物，作为肥大细胞稳定剂，对治疗哮喘和过敏性结膜炎有效。
T15772	Lodoxamide tromethamine U-42585E	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Lodoxamide tromethamine 是一种的肥大细胞稳定剂，具有抗过敏特性，可用于治疗哮喘和过敏性结膜炎的研究。
T60028	MM41	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	MM41 是一种人类端粒和基因启动子 DNA 四链体稳定剂，对 MIA PaCa-2 胰腺癌细胞系的 IC50 <10 nM。
T21648	CP-31398 dihydrochloride CP 31398 dihydrochloride	p53	Apoptosis
	CP-31398 dihydrochloride 是一种 p53 稳定剂，可稳定 p53 的活性构象并促进具有突变型或野生型 p53 的癌细胞系中的 p53 活性。
T6488	Epinastine hydrochloride Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Epinastine hydrochloride (WAL-801CL HCl) 是抗组胺剂和肥大细胞稳定剂，是一种可口服的选择性组胺 H1 受体拮抗剂，可抑制 IL-8 释放，具有抗过敏作用。
T4470	Pyridostatin TFA	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	Pyridostatin TFA 是一种 G-四链体稳定剂，靶向原癌基因 Src，降低人乳腺癌细胞 SRC 蛋白水平和 SRC 依赖的细胞运动。它通过诱导复制和转录依赖的 DNA 损伤促进人类癌细胞生长停滞。
T19820	MOPS sodium salt MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt	Others	Others
	MOPS sodium salt (MOPS-Na) 在生物学中常用作缓冲剂。其中MOPS 缓冲液能使哺乳动物细胞培养基的 pH 值保持稳定。
T35841	5-Benzyloxygramine	Dopamine Receptor; 5-HT Receptor	GPCR/G Protein; Neuroscience
	5-Benzyloxygramine 是一种 N 蛋白、蛋白互作的原位稳定剂，具有抗病毒和稳定 N-NTD 蛋白的作用。它能够阻断多巴胺受体，可拮抗 5-HT 对大鼠子宫和兔耳的作用。
T30587	Brl 22321 Brl22321,Brl-22321
	Brl 22321 is a mast cell stabilizer.
T35319	Zy 15109 N-Acetyl-aspartyl magnesium glutamate,Zy15109,Magnesium N-acetyl-aspartylglutamate
	Zy 15109 can be used as inhaled mast cell stabilizer.
T31364	Dehydelone KOS1584,SK-10088,KOS-1584,R-1645,SK10088,R1645
	Dehydelone(KOS-1584, R-1645, SK-10088) is a microtubule stabilizer that may be used in the treatment of non-small cell lung cancer.
T38326	Cromolyn (sodium salt hydrate)
	Cromolyn is a chromone complex that acts as a mast cell stabilizer, preventing the release of histamine. Its mechanism of action is thought to involve an interference with the antigen-stimulated calcium transport across the mast cell membrane, thereby inhibiting mast cell release of histamine, leukotrienes, and other substances that cause hypersensitivity reactions.
T21462	Olopatadine Opatanol,Patanol,KW-4943A,KW-4679
	Olopatadine, an antihistamine, as well as anticholinergic and mast cell stabilizer, is used for the treatment of itching associated with allergic conjunctivitis (eye allergies). There is also a potential for Olopatadine to treat steroid rebound (red skin
T60366	Epinastine
	Epinastine (WAL801) 是一种抗组胺剂和肥大细胞稳定剂。Epinastine 是一种有效的，选择性的，口服活性的组胺 H1 受体 (histamine H1 receptor) 拮抗剂。Epinastine 还抑制人嗜酸性粒细胞释放 IL-8 并具有抗过敏作用。
T69059	Cromoglicate sodium hydrate
	Cromoglicic acid , cromolyn (USAN), cromoglycate (former BAN), or cromoglicate, is traditionally described as a mast cell stabilizer, and is commonly marketed as the sodium salt sodium cromoglicate or cromolyn sodium. This drug prevents the release of inflammatory chemicals such as histamine from mast cells. Because of their convenience (and perceived safety), leukotriene receptor antagonists have largely replaced it as the non-corticosteroid treatment of choice in the treatment of asthma. Cro...
T73336	Ketotifen 酮替芬,HC 20-511
	Ketotifen (HC 20-511)为第二代口服活性非竞争性组胺1(H1)受体阻滞剂兼肥大细胞稳定剂，能体外阻断6-磷酸葡萄糖酸脱氢酶(6-PGD)。其对SARS-CoV-2及流感病毒(Influenza virus)展现出抗病毒活性，适用于自身免疫性脑脊髓炎(EAE)与哮喘发作预防研究。

化合物

Cromoglicic acid

Cat.No: T8239

Target: Others

Cat.No: T0211

Synonym: Azelastina,Astelin,Azelastinum,氮卓斯汀

Target: SARS-CoV, Histamine Receptor

Cat.No: T4566

Synonym: Lodoxamidum,洛草氨酸

Target: GPR, Histamine Receptor

Lodoxamide tromethamine

Cat.No: T15772

Synonym: U-42585E

Target: Histamine Receptor

Cat.No: T60028

Target: DNA/RNA Synthesis

CP-31398 dihydrochloride

Cat.No: T21648

Synonym: CP 31398 dihydrochloride

Target: p53

Epinastine hydrochloride

Cat.No: T6488

Synonym: Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat

Target: 5-HT Receptor, Histamine Receptor

Pyridostatin TFA

Cat.No: T4470

Target: DNA/RNA Synthesis

MOPS sodium salt

Cat.No: T19820

Synonym: MOPS-Na,3-(N-morpholino)propanesulfonic acid sodium salt,3-吗啉丙磺酸钠盐,Sodium 3-Morpholinopropanesulfonate,4-Morpholinepropanesulfonic acid, sodium salt

Target: Others

5-Benzyloxygramine

Cat.No: T35841

Target: Dopamine Receptor, 5-HT Receptor

Cat.No: T30587

Synonym: Brl22321,Brl-22321

Cat.No: T35319

Synonym: N-Acetyl-aspartyl magnesium glutamate,Zy15109,Magnesium N-acetyl-aspartylglutamate

Cat.No: T31364

Synonym: KOS1584,SK-10088,KOS-1584,R-1645,SK10088,R1645

Cromolyn (sodium salt hydrate)

Cat.No: T38326

Cat.No: T21462

Synonym: Opatanol,Patanol,KW-4943A,KW-4679

Cat.No: T60366

Cromoglicate sodium hydrate

Cat.No: T69059

Cat.No: T73336

Synonym: 酮替芬,HC 20-511

Cat. No.	Product Name	Target	Signaling Pathways
T0968	Paclitaxel Taxol,紫杉醇,NSC 125973	Apoptosis; Microtubule Associated; Autophagy	Apoptosis; Autophagy; Cytoskeletal Signaling
	Paclitaxel (Taxol) 属于天然产物，是一种微管聚合物稳定剂。Paclitaxel 具有抗肿瘤活性；通过诱导有丝分裂停滞、细胞凋亡、细胞自噬等，导致细胞死亡。
T75573	Taccalonolide E
	Taccalonolide E 是一种微管稳定剂，诱导癌细胞凋亡 (apoptosis)。

天然产物

Cat.No: T0968

Synonym: Taxol,紫杉醇,NSC 125973

Target: Apoptosis, Microtubule Associated, Autophagy

Taccalonolide E

Cat.No: T75573

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