1
43
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T13138 |
TGFBR1-IN-1
|
ALK | Angiogenesis; Tyrosine Kinase/Adaptors |
TGFBR1-IN-1 is an inhibitor of ALK5 (IC50 of 10-100 nM). |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-00500 |
Latent TGF beta 1 Protein, Mouse, Recombinant (His)
transforming growth factor, beta 1,TGF β1,Tgfb-1,TG... |
Mouse | HEK293 Cells |
Latent TGF beta 1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202. | |||
TMPJ-00249 |
TGF beta 1 Protein, Human, Recombinant (Avi), Biotinylated
TGF-Beta-1,TGFB1,Transforming Growth Factor β-1,Lat... |
Human | HEK293 Cells |
Transforming Growth Factor β-1 (TGFβ-1) is a secreted protein which belongs to the TGF-β family. TGFβ-1 is abundantly expressed in bone, articular cartilage and chondrocytes and is increased in osteoarthritis (OA). TGFβ-1 performs many cellular functions, including the control of cell growth, cell proliferation, cell differentiation and apoptosis. The precursor is cleaved into a latency-associated peptide (LAP) and a mature TGFβ-1 peptide. TGFβ-1 may also form heterodimers with other TGFβ family... | |||
TMPY-00413 |
Latent TGF beta 2 Protein, Mouse, Recombinant (His)
Tgfb-2,Tgf-beta2,TGF-beta 2,Tgf-β2,TGFB2,T... |
Mouse | HEK293 Cells |
TGF beta 2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090. | |||
TMPY-01133 |
Latent TGF beta 1 Protein, Human, Recombinant (His)
CED,DPD1,transforming growth factor, beta 1,TGF β1,LAP,转化生长因... |
Human | HEK293 Cells |
Latent TGF beta 1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2. | |||
TMPY-05313 |
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated
transforming growth factor, beta 1,transforming growth facto... |
Mouse | HEK293 Cells |
Latent TGF beta 1 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.7 kDa and the accession number is P04202. | |||
TMPJ-00622 |
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His)
转化生长因子,Transforming growth factor β-1,Latent TGF-β1,TGFB... |
Cynomolgus | HEK293 Cells |
Latent TGF-beta 1 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with N-6xHis tag. The predicted molecular weight is 11 and 35-45 KDa and the accession number is F7HCV5. | |||
TMPJ-00772 |
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated
Transforming growth factor β-1,Latent TGF-β1,TGFB1,... |
Mouse | HEK293 Cells |
Latent TGF-beta 1 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 35-45 KDa and the accession number is P04202. | |||
TMPY-05521 |
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated
TGFB,TGF β1,转化生长因子,TGF-beta 1,transforming growth f... |
Human | HEK293 Cells |
Latent TGF beta 1 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 42.4 kDa and the accession number is A0A499FJK2. | |||
TMPJ-00250 |
LAP (TGF-beta 1) Protein, Human, Recombinant (His & Avi), Biotinylated
transforming growth factor β1,TGFβ,CED,TGFB,TGF... |
Human | HEK293 Cells |
Transforming growth factor beta (TGFβ) family members are secreted in inactive complexes with a latency-associated peptide (LAP), a protein derived from the N-terminal region of the TGFβ gene product. Extracellular activation of these complexes is a critical step in regulation of TGFβ function in vivo. The TGFβ1 LAP is a ligand for the integrin αvβ6 and that αvβ6-expressing cells induce spatially restricted activition of TGFβ1. And LAP identifies a novel CD4+/CD25+ regulatory T cell subset with ... | |||
TMPJ-00254 |
TGF beta 3 Protein, Human/Mouse/Rat, Recombinant
Latency-associated peptide,TGF-beta-3,Transforming growth fa... |
Human,Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 3(TGFB3) is a member of a TGF -β superfamily which is defined by theirstructural and functional similarities. TGFB3 is secreted as a complex with LAP. This latent form of TGFB3becomes active upon cleavage by plasmin, matrix metalloproteases, thrombospondin -1, and a subset ofintegrins. It binds with high affinity to TGF- β RII, a type II serine/threonine kinase receptor. TGFB3 is involved incell differentiation, embryogenesis and development.It is believed to regu... | |||
TMPY-05314 |
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated
transforming growth factor β2,TGF β2,转化生长因子,Tgfb-2,... |
Mouse | HEK293 Cells |
TGF beta 2 Protein, Mouse, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 46.9 kDa and the accession number is P27090. | |||
TMPJ-00771 |
TGF beta 1 Protein, Mouse/Rat, Recombinant
TGFB,TGFbeta,CEDLAP,TGF-beta-1,TGF-beta 1 ... |
Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 1 (TGFβ1) is the prototype of a growing superfamily of peptide growth factors and plays a prominent role in a variety of cellular processes, including cell-cycle progression, cell differentiation, reproductive function, development, motility, adhesion, neuronal growth, bone morphogenesis, wound healing, and immune surveillance. TGF-β1, TGF-β2 and TGF-β3 signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II)... | |||
TMPJ-00255 |
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated
ARVD,TGF-β3,TGFB3,转化生长因子,TGF-beta3 |
Human | HEK293 Cells |
TGF beta 3 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P10600. | |||
TMPY-00990 |
Lefty-A Protein, Human, Recombinant (hFc)
LEFTYA,left-right determination factor 2,LEFTA,TGFB... |
Human | HEK293 Cells |
left-right determination factor 2 (Lefty2), also known as Left-right determination factor A (Lefty A), endometrial bleeding associated factor (left-right determination, factor A transforming growth factor-beta superfamily), and transforming growth factor beta-4, is a member of the TGF-beta family of proteins. This protein is secreted and plays a role in left-right asymmetry determination of organ systems during development. Lefty2/Lefty A may also play a role in endometrial bleeding. Mutations i... | |||
TMPJ-00258 |
TGF beta 2 Protein, Human, Recombinant
Glioblastoma-derived T-cell suppressor factor,TGF-β-2,Transf... |
Human | HEK293 Cells |
Transforming growth factor beta-2 (TGF-β2) is a secreted protein which belongs to the TGF-beta family. It is known as a cytokine that performs many cellular functions and has a vital role during embryonic development. The precursor is cleaved into mature TGF-beta-2 and LAP, which remains non-covalently linked to mature TGF-beta-2 rendering it inactive. It is an extracellular glycosylated protein. It is known to suppress the effects of interleukin dependent T-cell tumors. Defects in TGFB2 may be... | |||
TMPK-00259 |
Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TGF-beta3,TGFβ,TGF-β,TGF-β3,TGFB3,ARVD,TGFβ3,转化生长因子... |
Human | HEK293 Cells |
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with N-His tag. The predi... | |||
TMPK-00258 |
Latent TGF beta 3 Protein, Human, Recombinant (His)
TGFβ3,转化生长因子,TGF-β3,TGF-beta3,TGFβ,TGF-β,ARVD,TGFB3... |
Human | HEK293 Cells |
Transforming growth factor-betas (TGF-βs) are multifunctional cytokines that have been implicated in the regulation of a broad range of biological processes, including cell proliferation, cell survival, and cell differentiation. And transforming growth factor beta3 (TGFbeta3) is a key protein involved in scar-free healing observed in embryos. Latent TGF beta 3 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with N-His tag. The predicted molecular weight is 45.9 kDa and t... | |||
TMPJ-00261 |
TGF beta 2 Protein, Mouse/Rat, Recombinant
transforming growth factor β-2,BSC-1 cell growth inhibitor,G... |
Mouse,Rat | HEK293 Cells |
Transforming growth factor beta 2 (TGF-β2) is a member of TGF-beta superfamily that shares a characteristic cysteine knot structure. Mice with TGF-β2 gene deletion show defects in development of cardiac, lung, craniofacial, limb, spinal column, eye, inner ear and urogenital systems. All TGF-β isoforms signal via the same heteromeric receptor complex, consisting of a ligand binding TGF-β receptor type II (TβR-II), and a TGF-β receptor type I (TβR-I). Signal transduction from the receptor to the n... | |||
TMPY-04577 |
TGF beta 2 Protein, Rhesus, Recombinant (His)
TGF-beta 2,transforming growth factor beta 2,transforming gr... |
Rhesus | HEK293 Cells |
TGF beta 2 Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is F6ZJW6. | |||
TMPY-05157 |
TGFBR2 Protein, Human, Recombinant (His)
LDS2B,FAA3,TAAD2,MFS2,TGFR-2,TGFbeta-RII,transformi... |
Human | Baculovirus Insect Cells |
TGFBR2 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 17.8 kDa and the accession number is P37173. | |||
TMPJ-00256 |
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated
Transforming growth factor β-3,Latent TGF-β3,TGF-β-3,TGFβ3,<... |
Human | HEK293 Cells |
Latent TGF-beta 3 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 12 and 37-45 KDa and the accession number is P10600. | |||
TMPY-00231 |
TGF beta 2 Protein, Canine, Recombinant (His)
transforming growth factor β2,转化生长因子,TGF-beta 2,TGF-β2,T... |
Canine | HEK293 Cells |
TGF beta 2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 47 kDa and the accession number is A0A8C0RRP5. | |||
TMPJ-00260 |
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated
TGFB2,TGF-β-2,TGF-beta-2,Transforming growth factor... |
Human | HEK293 Cells |
Latent TGF-beta 2 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-8xHis-Avi tag. The predicted molecular weight is 13 and 39-50 KDa and the accession number is P61812. | |||
TMPJ-00259 |
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated
G-TSF,转化生长因子,Cetermin,Transforming growth factor beta-2 prop... |
Human | HEK293 Cells |
TGF beta 2 Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with N-Avi tag. The predicted molecular weight is 10-14 KDa and the accession number is P61812. | |||
TMPJ-00238 |
Lefty-A Protein, Human, Recombinant (His)
Endometrial bleeding-associated factor,TGFB4,TGF-β-... |
Human | HEK293 Cells |
Left-right determination factor 2(LEFTY2) is a secreted protein which belongs to the TGF-beta family. Lefty was first identified in a screen for undifferentiated cell-specific cDNAs from the P19 mouse embryonal carcinoma cells. Its mRNA expression on the left side of the developing embryo earned the name “Lefty”. The human orthologue was initially identified as Ebaf, Endometrial bleeding associated factor. Lefty contains the six cysteine residues that are conserved among TGF-β related proteins a... | |||
TMPY-05508 |
TGFBR2 Protein, Human, Recombinant (hFc)
TGFβ-RII,TGFbeta-RII,MFS2,AAT3,transforming growth ... |
Human | HEK293 Cells |
TGFBR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.2 kDa and the accession number is P37173. | |||
TMPY-05810 |
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated
RIIC,TAAD2,AAT3,TGFβ-RII,FAA3,transforming growth factor, β ... |
Human | HEK293 Cells |
TGFBR2 Protein, Human, Recombinant (His & hFc), Biotinylated is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 43.4 kDa and the accession number is P37173. | |||
TMPK-00305 |
TGFBR1 Protein, Human, Recombinant (mFc & Avi)
tbetaR-I,TGFβRI,TGFbetaRI,LDS2A,ALK-5,TGF-beta RI,t... |
Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is P36897-1. | |||
TMPY-01009 |
TGFBI Protein, Human, Recombinant (His)
CDG2,CSD,EBMD,CSD1,CDGG1,CSD3,transforming growth factor, be... |
Human | HEK293 Cells |
TGFBI is an RGD-containing protein that binds to type I, II and IV collagens. The RGD motif is found in many extracellular matrix proteins modulating cell adhesion and serves as a ligand recognition sequence for several integrins. TGFBI plays a role in cell-collagen interactions and may be involved in endochondral bone formation in cartilage. TGFBI is induced by transforming growth factor-beta and acts to inhibit cell adhesion. Mutations in TGFBI are associated with multiple types of corneal dys... | |||
TMPJ-00335 |
TGFBR2 Protein, Mouse, Recombinant (His)
TGFR-2,TGF-beta type II receptor,Transforming growth factor-... |
Mouse | HEK293 Cells |
TGFBR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 25-38 KDa and the accession number is Q62312-2. | |||
TMPK-00328 |
TGFBR2 Protein, Human, Recombinant (mFc & Avi)
TAAD2,LDS2B,LDS2,MFS2,TGFBR2,AAT3,LDS1B,TGFβR2,Tbet... |
Human | HEK293 Cells |
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi) is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The pred... | |||
TMPY-03082 |
TGFBR2 Protein, Rat, Recombinant (hFc)
transforming growth factor, β receptor II,transforming growt... |
Rat | HEK293 Cells |
TGFBR2 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 43 kDa and the accession number is P38438. | |||
TMPJ-00333 |
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc)
Transforming growth factor-β receptor type II,TbetaR-II,TGF-... |
Mouse | HEK293 Cells |
TGFBR2 Protein, Mouse, Recombinant (aa 24-184, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 60-75 KDa and the accession number is Q62312. | |||
TMPY-03649 |
TGFBR3 Protein, Human, Recombinant (His)
βglycan,betaglycan,transforming growth factor, beta receptor... |
Human | Baculovirus Insect Cells |
TGFBR3 Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 42.2 kDa and the accession number is Q03167-1. | |||
TMPK-00329 |
TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated
LDS2B,TbetaR-II,TGFβR2,LDS2,RIIC,TGF-β RII/TGFBR2,T... |
Human | HEK293 Cells |
The TGFBR2 gene provides instructions for making a protein called transforming growth factor-beta (TGF-β) receptor type 2. This receptor transmits signals from the cell surface into the cell through a process called signal transduction. Through this type of signaling, the environment outside the cell affects activities inside the cell such as stimulation of cell growth and division. TGFBR2 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi... | |||
TMPK-00306 |
TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated
TGFbetaRI,TGFBR1,ALK-5,SKR4,LDS2A,TGFB... |
Human | HEK293 Cells |
transforming growth factor beta receptor 1 (TGFBR1), a key stimulator of tumor proliferation and metastasis, was a direct target of miR‑98‑5p. miR‑98‑5p overexpression resulted in the downregulation of TGFBR1 and the suppression of the viability, proliferation, migration and invasion of A549 and H1299 cells. TGFBR1 Protein, Human, Recombinant (mFc & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-mFc-Avi tag. The predicted molecular weight is 38.2 kDa and the accession number is... | |||
TMPJ-00334 |
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc)
TGF-β receptor type II,Tgfbr2,TGF-β receptor type-2... |
Mouse | HEK293 Cells |
TGFBR2 Protein, Mouse, Recombinant (aa 24-159, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 55-65 KDa and the accession number is Q62312-2. | |||
TMPY-02224 |
TGFBR3 Protein, Mouse, Recombinant (His)
transforming growth factor, β receptor III,TBRIII,AW215636,t... |
Mouse | HEK293 Cells |
TGFBR3 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.3 kDa and the accession number is A0A0R4J097. | |||
TMPY-03171 |
TGFBR2 Protein, Rhesus, Recombinant (hFc)
transforming growth factor, β receptor II,transforming growt... |
Rhesus | HEK293 Cells |
TGFBR2 Protein, Rhesus, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.4 kDa and the accession number is H9YUL0. | |||
TMPJ-01178 |
TGFBR1 Protein, Mouse, Recombinant (hFc)
ALK-5,ALK-5ALK5,TGFβRI,tβR-I,LDS1A,TGFbetaRI,TG... |
Mouse | HEK293 Cells |
TGF-beta RI, also called ALK-5, is an approximately 55 kDa type I transmembrane serine/threonine receptor kinase. In the presence of TGF-beta, TGF-beta RI forms a complex with, and is phosphorylated by, TGF-beta RII. Phosphorylated TGF-beta RI can then transiently bind and phosphorylate Smad2 and Smad3. TGF-beta functions as a tumor suppressor by inhibiting the cell cycle in the G1 phase. Administration of TGF-beta is able to protect against mammary tumor development in transgenic mouse models i... | |||
TMPH-01952 |
SPRY2 Protein, Human, Recombinant (His & Myc)
|
Human | E. coli |
Antagonist of fibroblast growth factor (FGF) pathways via inhibition of FGF-mediated phosphorylation of ERK1/2. Thereby acts as an antagonist of FGF-induced retinal lens fiber differentiation, may inhibit limb bud outgrowth and may negatively modulate respiratory organogenesis. Inhibits TGFB-induced epithelial-to-mesenchymal transition in retinal lens epithelial cells. Inhibits CBL/C-CBL-mediated EGFR ubiquitination. SPRY2 Protein, Human, Recombinant (His & Myc) is expressed in E. coli expressio... | |||
TMPH-02135 |
SPRED1 Protein, Human, Recombinant (His & Myc & SUMO)
|
Human | E. coli |
Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase. Negatively regulates hematopoiesis of bone marrow. Inhibits fibroblast growth factor (FGF)-induced retinal lens fiber differentiation, probably by inhibiting FGF-mediated phosphorylation of ERK1/2. Attenuates actin stress fiber formation via inhibition of TESK1-mediated phosphorylation of cofilin. Inhibits TGFB-induced epithelial-to-mesenchymal transition in lens epithelial cells. SPRED1 Protein, Human, Reco... | |||
TMPJ-00325 |
BMPR1A/ALK-3 Protein, Human, Recombinant (hFc & His)
BMP Type-1A Receptor,Bone Morphogenetic Protein Receptor Typ... |
Human | HEK293 Cells |
Bone Morphogenetic Protein Receptor Type-1A (BMPR1A) belongs to the TKL Ser/Thr protein kinase family and TGFB receptor subfamily, including the type I receptors BMPR1A and BMPR1B and the type II receptor BMPR2. BMPR1A is a single-pass type I membrane protein and highly expressed in skeletal muscle. BMPR1A contains one GS domain and one protein protein kinase domain. BMPR1A is necessary for the extracellular matrix depostition by osteoblasts. BMPR1A can activate SMAD transcriptional regulators, ... |