16
1
37
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T19850L |
Semaglutide Acetate
索玛鲁肽醋酸盐,Semaglutide Acetate(910463-68-2 Free base) |
Glucagon Receptor | GPCR/G Protein |
Semaglutide Acetate 是胰高血糖素样肽 1 (GLP-1) 受体的激动剂,可用于治疗 2 型糖尿病的研究。 | |||
T6125 |
Semagacestat
LY450139,塞美司他 |
Beta Amyloid; Gamma-secretase | Neuroscience; Proteases/Proteasome; Stem Cells |
Semagacestat (LY450139) 是一种γ-secretase 抑制剂,抑制β-amyloid(Aβ42),Aβ38和Aβ40,IC50分别为 10.9,12 和 12.1 nM,可用于研究阿尔茨海默病。 | |||
T2064 |
Semaxinib
司马沙尼,SU5416 |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
Semaxinib (SU5416) 是一种选择性的 VEGFR(Flk-1/KDR) 抑制剂,其 IC50=1.23 μM。 | |||
T19850 |
Semaglutide
索玛鲁肽,司美格鲁肽,索马鲁肽 |
Glucagon Receptor | GPCR/G Protein |
Semaglutide 是人胰高血糖素样肽-1受体激动剂,是一种人胰高血糖素样肽-1 的长效类似物。它有用于 2 型糖尿病研究的潜力。 | |||
T3574 |
Sematilide hydrochloride
司美利特,CK-1752A,CK-1752,Sematilide HCl |
Potassium Channel | Membrane transporter/Ion channel |
Sematilide hydrochloride (CK-1752) 是一种选择性的 IKr 通道阻滞剂。Sematilide 以浓度依赖性抑制延迟整流钾通道 (K+current),IC50为 25 μM。Sematilide 是一种 III 类抗心律不齐剂。 | |||
T2496 |
(Z)-Semaxinib
SU5416 |
VEGFR | Angiogenesis; Tyrosine Kinase/Adaptors |
(Z)-Semaxinib (SU5416) 是一种有效的选择性 VEGFR(Flk-1/KDR) 抑制剂 (IC50: 1.23 μM),对 VEGFR 的选择性是 PDGFRβ 的 20 倍,对 FGFR、InsR 和 EGFR 没有抑制作用。 Semaxanib 是一种具有潜在抗肿瘤活性的喹诺酮衍生物。 | |||
T21268L |
Semax acetate(80714-61-0 free base)
|
Others | Others |
Semax acetate(80714-61-0 free base) 是一种合成的促肾上腺皮质激素 (ACTH) 肽类似物,具有神经保护、镇痛和抗焦虑特性。 | |||
T35593 |
Semapimod tetrahydrochloride
CPSI-2364 tetrahydrochloride |
TLR; MAPK | Immunology/Inflammation; MAPK |
Semapimod tetrahydrochloride (CPSI-2364 tetrahydrochloride) 是一种合成鸟腙丝裂原活化蛋白激酶阻滞剂,也是促炎细胞因子生成抑制剂,干扰巨噬细胞和小胶质细胞功能。Semapimod tetrahydrochloride 可抑制 TLR4 信号传导,抑制 TNF-α、IL-1β 和 IL-6,可用于研究克罗恩病和其他炎症。 | |||
T12878 |
Semaglutide TFA (910463-68-2 free base)
Semaglutide TFA |
Glucagon Receptor | GPCR/G Protein |
Semaglutide TFA is a agonist of glucagon-like peptide-1 (GLP-1) receptor,with a potential for type 2 diabetes treatment. | |||
T79304 |
Semapimod
CPSI-2364,CNI-1493 free base |
||
Semapimod是一种抑制促炎细胞因子产生的化合物,具有抑制TNF-α、IL-1β和IL-6功能。它通过抑制巨噬细胞的p38 MAPK以及一氧化氮的生成发挥作用,并且能够抑制TLR4信号传导(IC50约为0.3 μM)。Semapimod对于治疗各类炎症和自身免疫性疾病显示出潜在效用。 | |||
T125571 |
Eriosematin A
|
||
Eriosematin A 是一种有用的有机化合物,可用于生命科学领域的相关研究,其产品编号为 T125571。 | |||
T34610 |
Semapimod hydrochloride dihydrate
|
||
Semapimod hydrochloride dihydrate is a biochemical. | |||
T12879 |
Sematilide
CK-1752 |
Others | Others |
Sematilide is a blocker of selective IKr channel. | |||
T21268 |
Semax
|
||
Semax is a synthetic peptide analog of adrenocorticotropic hormone (ACTH) that has neuroprotective, analgesic, and anxiolytic properties. | |||
T34610L |
Semapimod mesylate
Semapimod tetramesylate |
||
Semapimod mesylate is a biochemical. | |||
T81180 |
Semastatin-5B
|
||
Semastatin-5B是一种含有17个氨基酸的抗血管生成肽,源自带有I型血栓反应蛋白基序的蛋白。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T11223 | Eriosematin | Others | Others |
Eriosematin has anti-proliferative and apoptosis-inducing properties and is a compound extracted from the root of Flemingia philippinensis in the Philippines. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-01906 |
SEMA4D Protein, Human, Recombinant (His)
CD100,COLL4,C9orf164,semaphorin 4D,SEMAJ,c... |
Human | HEK293 Cells |
SEMA4D Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80.7 kDa and the accession number is AAH54500.1. | |||
TMPY-04625 |
SEMA3A Protein, Mouse, Recombinant (His)
SemD,Semad,Hsema-I,SEMA1,coll-1,<... |
Mouse | HEK293 Cells |
SEMA3A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 61.6 kDa and the accession number is A0A803Z7F8. | |||
TMPY-00124 |
SEMA3A Protein, Human, Recombinant (hFc)
sema domain, immunoglobulin domain (Ig), short basi... |
Human | HEK293 Cells |
SEMA3A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.7 kDa and the accession number is Q14563. | |||
TMPJ-01176 |
SEMA4C Protein, Mouse, Recombinant (hFc)
M-Sema F,Semaphorin-C-like 1,Sema... |
Mouse | HEK293 Cells |
Semaphorin-4C is a protein which belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. As cell surface receptor for PLXNB2, it plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. It required for normal brain development, axon guidance and cell migration, Probable signaling receptor which may play a role in myogenic differentiation through activation of the str... | |||
TMPK-00741 |
SEMA7A Protein, Human, Recombinant (His)
Semaphorin-L,SEMAK1,CD108,MGC126692,Se... |
Human | HEK293 Cells |
SEMA7A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is O75326-1. | |||
TMPK-01216 |
SEMA7A Protein, Mouse, Recombinant (His)
Sema7A,H-SEMA-K1,JMH,Semaphorin-K... |
Mouse | HEK293 Cells |
SEMA7A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 69.5 kDa and the accession number is Q9QUR8. | |||
TMPY-01843 |
SEMA6A Protein, Human, Recombinant (His)
HT018,VIA,sema domain, transmembrane domain (TM), a... |
Human | HEK293 Cells |
SEMA6A, the first identified class 6 semaphorin, is contributed to regulate vascular development and adult angiogenesis. SEMA6A could inhibit proliferation, migration, and invasion in different glioma cell lines. That SEMA6A may be a potential prognostic biomarker in the treatment of GBM. Among different semaphorins tested by reverse transcriptase-polymerase chain reaction in human immune cells, the expression of class 6 transmembrane semaphorin SEMA6A was restricted to dendritic cells (DCs). | |||
TMPJ-01293 |
SEMA3C Protein, Human, Recombinant (His)
Semaphorin-E,SEMA3C,SEMAE,Sem... |
Human | HEK293 Cells |
Semaphorin 3C is one of six Class 3 secreted semaphorins, which are potent chemorepellents, that play a role in axon and/or vascular guidance during development can be up-regulated in the process of tumor progression. Semaphorin 3C consists of a 20 amino acids signal sequence, a N-terminal Sema domain, a cysteine knot, a furine-type cleavage site, an Ig-like domain, and a C-terminal basic domain. Semaphorin 3C expressed highly in the heart, colon, skeletal muscle, small intestine, testis, ovary ... | |||
TMPJ-00395 |
SEMA4D Protein, Mouse, Recombinant (hFc)
Semacl2,Sema J,Semaphorin-C-like ... |
Mouse | HEK293 Cells |
SEMA4D is a member of the semaphorin family,contains one Ig-like C2-type domain, one PSI domain and one Sema domain. SEMA4D is strongly expressed in lymphoid tissues, especially in the thymus, as well as in the nervous tissues. However, SEMA4D is expressed at lower levels in testes, brain, kidney, small intestine, prostate, heart, placenta, lung and pancreas, but not in colon and liver. SEMA4D is a cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. S... | |||
TMPJ-01169 |
SEMA4A Protein, Mouse, Recombinant (His)
Semaphorin-4A,Semaphorin-B,Semab,... |
Mouse | HEK293 Cells |
Semaphorin-4A (SEMA4A) belongs to the semaphorin family which contains a Ig-like C2-type domain, a PSI domain and a Sema domain. SEMA4A is expressed from day 10 in the embryo, and low levels are found between days 10-12. SEMA4A is a cell surface receptor for PLXNB1, PLXNB2, PLXNB3 and PLXND1 that plays an important role in cell-cell signaling. It plays a role in priming antigen-specific T-cells, promotes differentiation of Th1 T-helper cells, and thereby contributes to adaptive immunity. SEMA4A ... | |||
TMPJ-00383 |
SEMA3A Protein, Human, Recombinant (His & Flag)
Hsema-III,SemD,SEMA3A,Semaphorin ... |
Human | HEK293 Cells |
emaphorin-3A is a secreted protein which belongs to the semaphorin family. Semaphorins are a family of secreted and cell-bound signaling molecules defined by the presence of a common 500 aa Sema domain.This protein can function as either a chemorepulsive agent, inhibiting axonal outgrowth, or as a chemoattractive agent, stimulating the growth of apical dendrites. In both cases, the protein is vital for normal neuronal pattern development. Increased expression of this protein is associated with s... | |||
TMPY-05780 |
SEMA4D Protein, Human, Recombinant (hFc)
coll-4,CD100,C9orf164,SEMAJ,M-sema-G,COLL4... |
Human | HEK293 Cells |
SEMA4D Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 105.95 kDa and the accession number is AAH54500.1. | |||
TMPY-02360 |
SEMA3A Protein, Mouse, Recombinant (hFc)
Semad,Hsema-I,coll-1,sema domain,... |
Mouse | HEK293 Cells |
SEMA3A Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 87.7 kDa and the accession number is O08665. | |||
TMPK-01379 |
SEMA4D Protein, Cynomolgus, Recombinant (His)
Semaphorin-4D,FLJ33485,FLJ46484,SEMA4D,FLJ... |
Cynomolgus | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression. SEMA4D Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 80.1 kDa and the accession number is A0A2K5TZC9. | |||
TMPK-00403 |
SEMA4D Protein, Human, Recombinant (His & Avi)
CD100,FLJ34282,SEMA4D,Semaphorin-4D,coll-4... |
Human | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression. SEMA4D Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 82.1 kDa and the accession number is Q92854-1. | |||
TMPK-00404 |
SEMA4D Protein, Human, Recombinant (His & Avi), Biotinylated
FLJ39737,CD100,SEMAJ,C9orf164,FLJ34282,M-sema |
Human | HEK293 Cells |
Semaphorin 4D (Sema4D) is a multifunctional protein widely expressed in an organism that plays an important role in the control of many physiological and pathological processes, including immunoregulation, neurogenesis, angiogenesis, and tumor progression. SEMA4D Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 82.1 kDa and the accession number is Q92854-1. | |||
TMPY-02006 |
SEMA4A Protein, Human, Recombinant (hFc)
CORD10,SEMAB,RP35,semaphorin 4A,SEMB |
Human | HEK293 Cells |
SEMA4A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 99 kDa and the accession number is Q9H3S1-1. | |||
TMPK-01034 |
SEMA4B Protein, Mouse, Recombinant (His)
SEMA4B,SemC,Semaphorin-C,MGC131831,Sem... |
Mouse | HEK293 Cells |
Semaphorin 4B (SEMA4B) inhibits the invasion of non-small cell lung cancer (NSCLC) through PI3K-dependent suppression of MMP9 activation. SEMA4B may induce FoxO1 nuclear retention through suppressing PI3K/Akt signaling pathway, which subsequently inhibited cell growth through the direct nuclear target of FoxO1, p21. A role of SEMA4B in suppressing NSCLC growth, besides its role in inhibiting cell metastasis, and highlights SEMA4B as a promising therapeutic target for NSCLC. | |||
TMPY-03152 |
SEMA5A Protein, Mouse, Recombinant (His)
5930434A13,serpin peptidase inhibitor, clade F,9130201M22Rik... |
Mouse | HEK293 Cells |
SEMA5A Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 85.1 kDa and the accession number is Q3UPZ0. | |||
TMPY-01857 |
SEMA4A Protein, Human, Recombinant (His)
SEMB,CORD10,semaphorin 4A,SEMAB,RP35 |
Human | HEK293 Cells |
SEMA4A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 73.4 kDa and the accession number is Q9H3S1-1. | |||
TMPY-02187 |
SEMA5A Protein, Human, Recombinant (hFc)
SEMAF,serpin peptidase inhibitor, clade F,semF |
Human | HEK293 Cells |
SEMA5A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 110.7 kDa and the accession number is Q13591. | |||
TMPH-03369 |
SEMA3A Protein, Rat, Recombinant (His)
|
Rat | E. coli |
May be involved in guiding growing axons towards their targets by forming a molecular boundary that instructs axons to engage in the formation of specific nerve tracts. Binds to neuropilin. Involved in the development of the olfactory system and in neuronal control of puberty. SEMA3A Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 90.6 kDa and the accession number is Q63548. | |||
TMPY-01570 |
SEMA5A Protein, Human, Recombinant (His)
serpin peptidase inhibitor, clade F,SEMAF,semF |
Human | HEK293 Cells |
SEMA5A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 107 kDa and the accession number is Q13591. | |||
TMPJ-01355 |
SEMA4G Protein, Human, Recombinant (His)
Semaphorin-4G,SEMA4G,KIAA1619 |
Human | HEK293 Cells |
Semaphorin-4G is belongs to the semaphorin family, contains 1 Ig-like C2-type domain, 1 PSI domain, 1 Sema domain. Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and ve... | |||
TMPY-01836 |
SEMA4D Protein, Mouse, Recombinant (His)
Semacl2,coll-4,CD100,semaphorin 4D,Sem... |
Mouse | HEK293 Cells |
SEMA4D Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80.2 kDa and the accession number is O09126. | |||
TMPJ-01349 |
SEMA4B Protein, Human, Recombinant (His)
SEMAC and SEMA4B,KIAA1745,Semapho... |
Human | HEK293 Cells |
The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. SEMA4B negatively regulates basophil-mediated Th2 and humoral memory responses. | |||
TMPY-00532 |
SEMA4D Protein, Rhesus, Recombinant (His)
semaphorin 4D |
Rhesus | HEK293 Cells |
SEMA4D Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 80.7 kDa and the accession number is A0A8J8Y3Y5. | |||
TMPY-03164 |
SEMA4D Protein, Rat, Recombinant (hFc)
semaphorin 4D |
Rat | HEK293 Cells |
SEMA4D Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 103.4 kDa and the accession number is A0A8I6G5Q1. | |||
TMPY-03095 |
SEMA4D Protein, Rat, Recombinant (His)
semaphorin 4D |
Rat | HEK293 Cells |
SEMA4D Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 77.8 kDa and the accession number is A0A8I6G5Q1. | |||
TMPH-02446 |
SEMA4D Protein, Rhesus macaque, Recombinant (His)
|
Rhesus | HEK293 Cells |
SEMA4D Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-10xHis tag. The predicted molecular weight is 81.9 kDa and the accession number is H9FNS0. | |||
TMPJ-01348 |
SEMA4B Protein, Human, Recombinant (hFc & His)
SEMAC,Semaphorin-4B,KIAA1745,SEMA... |
Human | HEK293 Cells |
Semaphorin-4B is a single-pass type I membrane protein. SEMA4B is a member of the semaphorin family. The class 4 semaphorins are integral membrane proteins that are widely expressed throughout the nervous system. SEMA4B is a single-pass type I membrane protein and contains one Ig-like C2-type (immunoglobulin-like) domain, one PSI domain and one Sema domain. Human SEMA4B is expressed in neurons. SEMA4B inhibits axonal extension by providing local signals to specify territories inaccessible for gr... | |||
TMPH-02077 |
Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc)
|
Human | HEK293 Cells |
Semaphorin-3G/SEMA3G Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPH-02074 |
Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His)
|
Human | E. coli |
Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His) is expressed in E. coli. | |||
TMPJ-00396 |
SEMA4D Protein, Human, Recombinant (aa 22-734, His)
A8,BB18,Semaphorin-4D,GR3,CD100 |
Human | HEK293 Cells |
Semaphorin-4D is also known as A8,BB18, GR3, CD100. Semaphorin-4D belongs to the semaphorin family containing 1 Ig-like C2-type domain, 1 PSI domain and 1 Sema domain. It is the cell surface receptor for PLXN1B and PLXNB2 that plays an important role in cell-cell signaling. It promotes the migration of cerebellar granule cells and of endothelial cells, regulates dendrite and axon branching and morphogenesis. Semaphorin-4D Plays a role in the immune system; Promotes signaling via SRC and PTK2B/P... | |||
TMPH-02076 |
Semaphorin-3F/SEMA3F Protein, Human, Recombinant (His & Myc)
|
Human | HEK293 Cells |
Semaphorin-3F/SEMA3F Protein, Human, Recombinant (His & Myc) is expressed in HEK293. | |||
TMPH-02075 |
Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc)
|
Human | Baculovirus Insect Cells |
Semaphorin-3B/SEMA3B Protein, Human, Recombinant (His & Myc) is expressed in Baculovirus. | |||
TMPJ-00415 |
HGFR/c-Met Protein, Human, Recombinant (aa 25-932, His & Avi), Biotinylated
SF receptor,HGF receptor,Scatter factor receptor,Tyrosine-pr... |
Human | HEK293 Cells |
Hepatocyte growth factor receptor (HGF R) is a glycosylated receptor tyrosine kinase that plays a central role in epithelial morphogenesis and cancer development. HGF R is synthesized as a single chain precursor which undergoes cotranslational proteolytic cleavage. Mature HGF R is a disulfide-linked dimer composed of a 50 kDa extracellular α chain and a 145 kDa transmembrane β chain. Proteolysis and alternate splicing generate additional forms of human HGF R which either lack of the kinase domai... |