135
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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T21510 |
PSI
|
Proteasome | Proteases/Proteasome; Ubiquitination |
PSI 是蛋白酶体proteasome 抑制剂。它对原发性渗出性淋巴瘤 (PEL) 细胞的增殖具有抑制作用。它可用于 KSHV 相关淋巴瘤、卡波济氏肉瘤相关疱疹病毒 (KSHV) 感染的研究。 | |||
T2117 |
PSI-6206
2'-deoxy-2'-fluoro-2'-C-methyluridine,RO 2433,GS-331007 |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
PSI-6206 (RO 2433) 是 PSI-6130 的脱氨衍生物,PSI-6206 是一种选择性 HCV RNA 聚合酶抑制剂,低效抑制HCV 复制,EC90为 >100 μM。PSI-6130 是一种有效的选择性 HCV NS5B 聚合酶抑制剂。 | |||
T38485L |
Fmoc-Gly-Ser(psi(Me,Me)pro)-OH acetate
|
Others | Others |
Fmoc-Gly-Ser(psi(Me,Me)pro)-OH acetate 是一种二肽。 | |||
T38662 |
Fmoc-Gly-Thr(psi(Me,Me)pro)-OH
|
Others | Others |
Fmoc-Gly-Thr(psi(Me,Me)pro)-OH 是一个二肽。 | |||
T16675 |
PSI-352938
PSI-938 |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
PSI-352938 is an inhibitor of hepatitis C virus nucleotide. | |||
T16710 |
Mericitabine
R-7128,RG 7128,PSI 6130 diisobutyrate |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
Mericitabine (R-7128) 是一种核苷HCV NS5B 聚合酶抑制剂。它充当 RNA 链终止子并防止 RNA 转录物在复制过程中延伸。 | |||
T6676 |
Sofosbuvir
索非布韦,GS 7977,PSI-7977 |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
Sofosbuvir (GS 7977) 是一种丙型肝炎病毒聚合酶 NS5B 的尿苷单磷酸类似物抑制剂,用作治疗慢性丙型肝炎的抗病毒剂。 | |||
T12571 |
PSI-6206 13C,d3
Sofosbuvir metabolite GS-331007 13CD3,RO-2433 13CD3,PSI-6206 13CD3,GS-331007 13CD3 |
Others | Others |
PSI-6206 13CD3 is the deuterium labeled PSI-6206. PSI-6206 is a potent and selective HCV NS5B polymerase inhibitor. | |||
T12572 |
PSI-7409
|
Others | Others |
PSI-7409 is the active 5'-triphosphate metabolite of Sofosbuvir (PSI-7977). | |||
T16676 |
PSI-697
P-Selectin Inhibitor |
Others | Others |
PSI-697 is an inhibitor of oral P-selectin (IC50: 125 μM). | |||
T13852 | PSI-7409 tetrasodium | Others | Others |
PSI-7409 tetrasodium is an active 5'-triphosphate metabolite of sofosbuvir (PSI-7977)(IC50s of 1.6, 2.8, 0.7 and 2.6 μM for GT 1b_Con1, GT 2a_JFH1, GT 3a, and GT 4a NS5B polymerases, respectively). | |||
T39150 |
Fmoc-Val-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Val-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41117 |
Fmoc-Ile-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Ile-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T40175 |
Fmoc-Ala-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Ala-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T38535 |
Fmoc-Ile-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Ile-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T39301 |
Fmoc-Val-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Val-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41111 |
Fmoc-Leu-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Leu-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T20160 |
GS-566500
psi-352707,psi352707,psi 352707 |
||
GS-566500 is a compound of Sofosbuvir metabolite. | |||
T41009 |
Fmoc-Tyr(tBu)-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Tyr(tBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41118 |
Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Lys(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41050 |
Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Glu(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41067 |
Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Asn(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T40415 |
Fmoc-Leu-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Leu-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T33079 | Lys-psi(CH2NH)-trp(nps)-ome | ||
Lys-psi(CH2NH)-trp(nps)-ome peptide bond replaced by CH2NH group. | |||
T38485 |
Fmoc-Gly-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Gly-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41112 |
Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Asp(OtBu)-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41080 |
Fmoc-Trp(Boc)-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Trp(Boc)-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T39260 |
Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Gln(Trt)-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41120 |
Fmoc-Asn(Trt)-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Asn(Trt)-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T39045 |
Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Gln(Trt)-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41066 |
Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Asp(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41053 |
Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Lys(Boc)-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41049 |
Fmoc-Trp(Boc)-Ser(psi(Me,Me)pro)-OH
|
||
Fmoc-Trp(Boc)-Ser(psi(Me,Me)pro)-OH is a dipeptide. | |||
T41119 |
Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Glu(OtBu)-Thr(psi(Me,Me)pro)-OH is a dipeptide. | |||
T27440 |
GS-9851
GS9851,GS 9851,PSI 7851,PSI7851,PSI-7851 |
||
GS-9851, a HCV nonstructural protein 5B (NS5B) inhibitor, is used potentially for the treatment of HCV infection. | |||
T70118 |
PSI-112
|
||
PSI-112 is a fibrinolysis inhibitor. | |||
T74301 |
PSI-353661
|
||
PSI-353661 (GS-558093) 是一种嘌呤核苷酸类NS5B 聚合酶抑制剂,可抵抗HCV 感染。PSI-353661抑制野生型和 S282T 抵抗性复制子HCV 的EC90s 分别为 8 nM 和 11 nM。PSI-353661 可在人原代肝细胞中产生高浓度的活性三磷酸。 | |||
T75869 |
PSI TFA
|
||
PSI (TFA) 是一种有效的蛋白酶体proteasome 抑制剂。PSI (TFA) 抑制原发性渗出性淋巴瘤 (PEL) 细胞的增殖。PSI (TFA) 可用于卡波济氏肉瘤相关疱疹病毒 (KSHV) 感染和 KSHV 相关淋巴瘤的研究。 | |||
T125963 | Psi Cb | ||
T12954 |
Sofosbuvir 13CD3
GS-7977 13CD3,PSI-7977 13CD3 |
Others | Others |
Sofosbuvir 13CD3 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active HCV RNA replication inhibitor in the HCV replicon assay, with potent anti-hepatitis C virus (HCV) activity. | |||
T12955 |
Sofosbuvir D6
PSI-7977 D6,GS-7977 D6 |
Others | Others |
Sofosbuvir D6 is the deuterium labeled Sofosbuvir. Sofosbuvir is an active inhibitor of HCV RNA replication in the HCV replicon assay, demonstrates potent anti-hepatitis C virus (HCV) activity. | |||
T64451 |
Fmoc-Phe-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Phe-Thr(psi(Me,Me)pro)-OH 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T64451,CAS号为 1196703-48-6。 | |||
T66617 |
Fmoc-Ala-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Ala-Thr(psi(Me,Me)pro)-OH 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66617,CAS号为 252554-79-3。 | |||
T25550 |
Jmv 176
Jmv-176,Jmv176,Boc-tyr(SO3)-nle-psi-(coch2)-gly-trp-nle-asp-phe-NH2 |
||
Jmv 176 is a CCK agonist when first given and becomes a cholecystokinin antagonist after 3-4 hours. | |||
T66611 |
Fmoc-Ser(tBu)-Ser(psi(Me,Me)pro)-OH
|
||
T67193 |
Fmoc-Ser(tBu)-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Ser(tBu)-Thr(psi(Me,Me)pro)-OH 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T67193,CAS号为 1266350-99-5。 | |||
T66619 |
Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH
|
||
Fmoc-Tyr(tBu)-Thr(psi(Me,Me)pro)-OH 是一种有用的有机化合物,可用于生命科学领域的相关研究。其产品编号为 T66619,CAS号为 920519-31-9。 | |||
T70117 |
Cyclanoline (free base)
|
||
Cyclanoline (free base) is an acetylcholinesterase inhibitor | |||
T7615L |
Xenopsin 2TFA(51827-01-1(free base)
|
Others | Others |
Xenopsin 2TFA(51827-01-1(free base) 是一种以前从两栖动物皮肤中分离出来的神经降压素样八肽。 | |||
T6015 |
Cathepsin Inhibitor 1
|
Cysteine Protease | Proteases/Proteasome |
Cathepsin inhibitor 1 是Cathepsin 的选择性抑制剂,能够抑制CatL(pIC50:7.9)、CatL2(pIC50:6.7)、CatS(pIC50:6.0)、CatK(pIC50:5.5)和CatB(pIC50:5.2)。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T7607 |
PSI-6130
R 1656,2'-去氧-2'-氟-2'-C-甲基胞苷 |
HCV Protease | Microbiology/Virology; Proteases/Proteasome |
PSI-6130 (R 1656) 是高效选择性 HCV NS5B 聚合酶抑制剂,抑制 HCV 复制,IC50值为 0.6 μM。 | |||
TN7233 |
Pseudobaptigenin
Psi-baptigenin |
Others | Others |
Pseudobaptigenin (Psi-baptigenin) 是一种异黄酮,是一种黄酮类脂质分子,是在Pterocarpus marsupium、Dalbergia spruceana 中发现的一种天然产品。 | |||
T2864 |
Lycopene
番茄红素,ψ,ψ-Carotene |
Reactive Oxygen Species; ROS | Immunology/Inflammation; Metabolism; NF-κB |
Lycopene (ψ,ψ-Carotene) 是一种番茄及其产品和其他红色水果和蔬菜中天然存在的类胡萝卜素,具有抗氧化活性。 | |||
TQ0065 |
Pseudobufarenogin
伪异沙蟾毒精,ψ-Bufarenogin |
Others | Others |
Pseudobufarenogin (ψ-Bufarenogin) 是一种蟾蜍毒素提取物,活性背景未知。 | |||
TN2429 |
Capsiate
|
Antioxidant; TRP/TRPV Channel | Membrane transporter/Ion channel; oxidation-reduction |
Capsiate 是一种具有口服活性的 TRPV1 激动剂,是非刺激性辣椒素类似物,可作为抗过敏剂,具有抗炎、抗氧、降糖和抑制血管生成活性。 | |||
T8101 |
Nepsilon-Acetyl-L-lysine
|
Others; Endogenous Metabolite | Metabolism; Others |
Nepsilon-Acetyl-L-lysine 是一种氨基酸赖氨酸衍生物。 | |||
TN7079 |
coreopsin
Butein-4-O-β-D-glucopyranoside,金鸡菊苷 |
Others | Others |
Coreopsin(Butein-4-O-β-D-glucopyranoside) 是金鸡菊的主要成分之一。在中国传统上被用于治疗高血压和糖尿病以及降低体重和血脂。 | |||
T3S0970 |
Thermopsine
Thermospine,黄华碱 |
Antibacterial | Microbiology/Virology |
Thermopsine (Thermospine) 是从槐豆亚种的果实,豆荚和茎皮中分离出来的一种喹诺酮类生物碱,具有抗菌活性。 | |||
TN6872 |
Trypsin
|
Protease-activated Receptor | GPCR/G Protein |
Trypsin 是一种可从鱼类分离出的丝氨酸蛋白酶,可水解赖氨酸或精氨酸羧基侧蛋白质。Trypsin 具有抗炎活性,可通过 PDCoV 的 S 糖蛋白与 pAPN 的相互作用诱导 PDCoV 感染的细胞膜融合,可激活 PAR2 和 PAR4,促进细胞增殖和分化。Trypsin 可用于促进伤口愈合和研究神经源性炎症。 | |||
TQ0302 |
Thapsigargin
毒胡萝卜素 |
Apoptosis; SARS-CoV; Calcium Channel | Apoptosis; Membrane transporter/Ion channel; Metabolism; Microbiology/Virology |
Thapsigargin 属于天然产物,是一种肌/内质网 Ca2+ ATP 酶 (SERCA) 的抑制剂,也是一种内质网应激诱导剂。Thapsigargin 通过阻断细胞将钙泵入肌浆和内质网的能力来提高胞浆钙浓度。 | |||
TN5900 |
O-Methylcedrelopsin
6,7-Dimethoxy-8-prenylcoumarin |
||
O-Methylcedrelopsin may have vasorelaxing activity. | |||
T22187 |
Amidepsine A
|
||
Amidepsine A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 T22187,CAS号为 169181-28-6。 | |||
TSP-40962729 |
Kopsine
|
||
T13732 |
Hydroxy-Epsilon-Sanshool
|
Others | Others |
Hydroxy-Epsilon-Sanshool is an alkyl amide isolated from Zanthoxylum bungeanum. Hydroxy-Epsilon-Sanshool produces key tingling and numbing chemosensation. | |||
T80998 |
Thapsigargicin
Thapsigargicine |
||
Thapsigargicin(Thapsigargicine)作为肥大细胞和白细胞的激活剂,能诱导大鼠腹膜肥大细胞及人嗜碱性粒细胞释放组胺,并提升完整人血小板中的细胞质游离钙水平。 | |||
T39168 |
Epsilon-(gamma-glutamyl)-lysine
Epsilon-(gamma-glutamyl)-lysine,γ-Glu-ε-Lys,H-Glu(H-Lys-OH)-OH |
||
Epsilon-(gamma-glutamyl)-lysine is an N(6)-acyl-L-lysine derivative that forms bonds between extracellular matrix (ECM) components with the assistance of the enzyme tissue transglutaminase (tTg). These bonds are implicated in the pathogenesis of certain diseases like non-diabetic kidney and glaucoma filtration. | |||
TN5830 |
Campsiketalin
Rengyoxide dimethyl ketal |
||
Campsiketalin 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN5830,CAS号为 93675-96-8。 | |||
T83612 |
(-)-11,12-Methylenedioxykopsinaline
|
||
(-)-11,12-Methylenedioxykopsinaline (Compound 4) 是一种从Kopsia officinalis中提取的单萜吲哚类生物碱。 | |||
T81975 |
Kopsininic acid
|
||
Kopsininic acid, 源自Kopsia hainanensis的天然产物,主要用于类风湿性关节炎、咽炎、扁桃体炎和水肿的研究。 | |||
TN4093 |
Galeopsin
|
TNF | Apoptosis |
Galeopsin shows potential anti-inflammatory activity by inhibiting proinflammatory cytokine TNF-α, it has anti-proliferative effect on several cancer cell lines. | |||
T12448 |
Phomopsin A
|
Others | Others |
Phomopsin A is a cyclic hexapeptide mycotoxin isolated from the fungus Phomopsis leptostomiformis. | |||
TN3898 |
Drimiopsin D
|
Others | Others |
Drimiopsin D is a natural product from Scilla scilloides. | |||
TN6475 |
Ampelopsin G
|
||
Ampelopsin G 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6475,CAS号为 151487-09-1。 | |||
TN6474 | Ampelopsin F | ||
Ampelopsin F is a natural product from Ampelopsis brevipedunculata var. hancei. | |||
TN2624 | 14-Deoxy-epsilon-caesalpin | Others | Others |
14-Deoxy-epsilon-caesalpin is a natural product from Caesalpinia minax HANCE. | |||
T75568 | Z-Antiepilepsirine | ||
Z-Antiepilepsirine 是一种酰胺生物碱,存在于 Piper capense L.f 中。Z-Antiepilepsirine 显示抗疟原虫活性,对 PlasmodiumfalciparumW2 菌株的 IC50值为 27 µM。 | |||
TN3897 |
Drimiopsin C
|
Others | Others |
Drimiopsin C is a natural product from Scilla scilloides. | |||
TN5346 |
Psiguadial D
|
||
Psiguadial D shows significant cytotoxicity toward HepG2 and HepG2/ADM cells. | |||
T82038 |
Isocoreopsin
Flavanocorepsin |
||
Isocoreopsin (Flavanocorepsin)为源自Butea monosperma花的抗癌化合物。 | |||
TN4839 | Psidial A | Others | Others |
Psidial A shows activity to enzyme PTP1B; it also reduces tumor growth and stimulate uterus proliferation. | |||
TN6213 | Ampelopsin A | ||
Ampelopsin A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6213,CAS号为 130608-11-6。 | |||
TN3156 | 6-Dehydroxy-8-hydroxygaleopsinolone | Others | Others |
6-Dehydroxy-8-hydroxygaleopsinolone 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3156,CAS号为 87440-66-2。 | |||
T83155 | Agonodepside B | ||
Agonodepside B, 分离自非孢子丝状真菌F7524,是一种化合物。 | |||
TN6249 | (+)-Isoampelopsin F | ||
(+)-Isoampelopsin F 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN6249,CAS号为 354553-38-1。 | |||
T60741 | Dihydrocapsiate | ||
Dihydrocapsiate 可用于研究代谢疾病,是二氢 capsinoid 家族的一种化合物。Dihydrocapsiate 口服有效的 TRPV1激动剂。 | |||
T81976 |
Kopsinine
|
||
Kopsinine,一种二氢吲哚生物碱,来源于长春花提取。 | |||
TN3617 |
Cedrelopsin
|
Others | Others |
Cedrelopsin shows significant inhibition against A549 cells with IC50 values of 3.6-5.9 ug/mL. | |||
T82787 |
Calythropsin
|
||
Calythropsin是一种对有丝分裂产生微弱影响的细胞毒性查尔酮类化合物,该化合物可能还会影响微管蛋白的聚合。 | |||
TN3011 |
4,5-Diepipsidial A
|
Others | Others |
4,5-Diepipsidial A 是一种天然产物,可用于生命科学领域的相关研究。其产品编号为 TN3011,CAS号为 1219603-97-0。 | |||
T35770 |
Cylindrospermopsin
|
||
Cylindrospermopsin, a tricyclic uracil derivative, is a cyanobacterial toxin that was first discovered in an algal bloom contaminating a local drinking supply on Palm Island in Queensland, Australia after an outbreak of a mysterious disease. Cylindrospermopsin targets protein and glutathione synthesis in hepatocytes (IC50s = 1.3 and 2.4 µM, respectively), leading to cell death. [1] It has been shown to inhibit the activity of the uridine monophosphate synthase complex with a Ki value of 10 &... |