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Search Results for " ifn-β "

Targets Recommended: Others IFNAR

33

抑制剂 & 化合物

3

天然产物

20

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T11630	IFN alpha-IFNAR-IN-1 hydrochloride	Others; IFNAR	Immunology/Inflammation; Others
	IFN alpha-IFNAR-IN-1 hydrochloride 是 IFN-α 和 IFNAR 相互作用的抑制剂。 IFN alpha-IFNAR-IN-1 hydrochloride 抑制 BM-pDCs 的 MVA 诱导的 IFN-α 反应，IC50 为 2-8 μM。
T12933	SM-276001	TLR; COX	Immunology/Inflammation; Neuroscience
	SM-276001 是可口服的干扰素诱导剂，是选择性TLR7激动剂，可以诱导抗肿瘤免疫反应。
T76637	IFN-γ Antagonist 1
	IFN-γAntagonist 1 (AYCRDGKIGPPKLDIRKEEKQI)，一种干扰素γ (IFN-γ) 拮抗剂，通过抑制IC50约为35 μM的IFN-γ诱导的HLR/DR抗原在Colo 205细胞上的表达展现作用。该化合物在免疫调节领域具有潜在应用。
T76638	IFN-γ Antagonist 1 acetate
	IFN-γAntagonist 1 (AYCRDGKIGPPKLDIRKEEKQI) acetate 作为一种干扰素 γ (IFN-γ) 拮抗剂，能够在 Colo 205 细胞中抑制 IFN-γ诱导的 HLR/DR 抗原表达，其 IC50 值约为 35 μM，显示出在免疫调节中的潜在应用价值。
T73486	RIG012	Others	Others
	RIG012 是一种有效的 RIG-I 抑制剂，用 NADH 偶联 ATPase 测得 IC50 值为 0.71 μM。RIG012 对 IFN-β 和 ISG hRsad2 表达有抑制作用。
T22142	RO8191 RO4948191,CDM-3008	HCV Protease; HBV; JAK; IFNAR; STAT	Angiogenesis; Chromatin/Epigenetic; Immunology/Inflammation; JAK/STAT signaling; Microbiology/Virology; Proteases/Proteasome; Stem Cells
	RO8191 (CDM-3008) 是干扰素 (IFN) 受体激动剂。它直接与 IFNα/β 受体 2 结合，激活 IFN 刺激的基因表达和 JAK/STAT 磷酸化。它通过具有干扰素样活性发挥 cccDNA 调节剂作用，并具有抗 HBV 活性。
T0097	MRT67307 MRT67307 HCl	IκB/IKK; Autophagy	Autophagy; NF-κB
	MRT67307 是一种IKKε和TBK-1的双抑制剂，IC50分别为 160 和 19 nM。它抑制细胞自噬，也可抑制ULK1和ULK2，IC50分别为 45 和 38 nM。
T5521	Bropirimine U-54461,溴匹立明	TLR	Immunology/Inflammation
	Bropirimine (U-54461) 是 toll 样受体 7(TLR7)的合成激动剂，可通过 TLR7 介导 IFN-β 的产生抑制破骨细胞前体细胞向破骨细胞分化。它是一种生物反应调节剂，通过诱导淋巴因子起作用，在膀胱和上尿路的原位移行细胞癌中具有抗癌活性。
T38162	STING18
	STING18 is a competitive ligand of stimulator of interferon genes (STING; IC50 = 0.068 μM in a radioligand binding assay).1 It inhibits cGAMP-induced IFN-β production (IC50 = 11 μM) but does not stimulate IFN-β production (EC50 = >30 μM) in THP-1 cells. \|1. Siu, T., Altman, M.D., Baltus, G.A., et al. Discovery of a novel cGAMP competitive ligand of the inactive form of STING. Med. Chem. Lett. 10(1), 92-97 (2019).
T76930	Bifarcept
	Bifarcept为一种针对干扰素受体I型(IFN-RI)的重组抗体，能与IFN-β结合，从而延长其在血清中的半衰期。
T64280	ODN 2216
	ODN 2216 是一种 TLR9 (toll-like receptor 9) 配体或激动剂，能够诱导产生大量的 IFN-α 和 IFN-β。ODN 2216 可以利用 pDC (浆细胞样 DC) 诱导 IFN-α，以及利用 DC (树突状细胞) 产生IL-12 (p40)。ODN 2216 能够间接的、在 IFN-α/β 介导下刺激外周血单核细胞 (PBMC) 产生 IFN-γ。ODN 2216 可以激活 NK 细胞，诱导 IFN-γ 产生 TCR 触发的 CD4+T 细胞。
T26895	BRD0476 BRD-0476,ML 187,ML187,ML-187,BRD 0476
	BRD0476 is a suppressor of pancreatic β-cell apoptosis. BRD0476 inhibits interferon-gamma (IFN-γ)-induced Janus kinase 2 (JAK2) and signal transducer and activation of transcription 1 (STAT1) signaling to promote β-cell survival. BRD0476 inhibits JAK-STAT
T38158	StA-IFN-1
	StA-IFN-1 is an inhibitor of the interferon (IFN) induction pathway with an IC50 value of 4.1 μM in a GFP reporter assay for IFN induction similar to TPCA-1 , which specifically inhibits the IKKβ component of the IFN induction pathway. It does not show inhibitory activity in a GFP reporter assay for IFN signaling in which ruxolitinib , which is specific for the IFN signaling component JAK1, is active. StA-IFN-1 reduces the levels of IFN-β, but not ISG MxA, mRNA, suggesting that it is selective f...
T71839	ATV399
	ATV399 is an inhibitor of iNOS dimerization which protects against Cytokine-Induced rat β-cell dysfunction, thereby inhibiting cleaved caspase-9 activation and subsequent β-cell apoptosis induced by a combination of IL-1β, IFN-γ, and high glucose.
T38329	CU-76
	CU-76 is an inhibitor of cyclic GMP-AMP synthase (cGAS; IC50= 0.24 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. CU-76 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas, R., Sun, L., Anderson, R., et al.Discovery of small-molecule cyclic GMP-AMP sy...
T38328	CU-32
	CU-32 is an inhibitor of cyclic GMP-AMP (cGAMP) synthase (cGAS; IC50= 0.45 μM).1It reduces DNA-, but not Sendai virus-, induced dimerization of IFN regulatory factor 3 in THP-1 cells, indicating selectivity for the cGAS DNA sensing pathway over the RIG-I-MAVS RNA sensing pathway. It is also selective for cGAS over toll-like receptors (TLRs) at 50 μM. CU-32 decreases IFN-stimulatory DNA-induced production of IFN-β in THP-1 cells when used at concentrations of 10, 30, and 100 μM. 1.Padilla-Salinas...
T39778	Influenza A virus-IN-1
	Influenza A virus-IN-1, a dihydropyrrolidones derivative, is a highly effective inhibitor of various subtypes of influenza A virus (IAV) with IC 50 values ranging from 3.11 μM to 7.13 μM. It effectively suppresses IAV replication and enhances the expression of key antiviral cytokines, such as IFN-β, and the antiviral protein MxA.
T69898	NG25 trihydrochloride
	NG25 trihydrochloride is a type II kinase inhibitor that inhibits MAP4K2 and TAK1. It also inhibits the Src family kinases Src and LYN and Abl family kinases as well as CSK, FER, and p38α. NG 25 prevents TNF-α-induced IKKα/β phosphorylation and IκB-α degradation in L929 cells. It inhibits secretion of IFN-α and IFN-β induced by CpG type B and CL097, respectively. NG 25 decreases cell viability of HCT116KRASWT, and to a greater degree of HCT116KRASG13D, colorectal cancer cells in a concentration...
T75092	STING agonist-24
	STINGagonist-24 (CF504) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING，增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。
T75093	STING agonist-25
	STINGagonist-25 (CF505) 是一种非核苷酸小分子 STING 激动剂。STINGagonist-23 激活 STING，增加 STING、TBK1和 IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。
T75096	STING agonist-28
	STINGagonist-28 (CF510) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING，增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。
T75094	STING agonist-26
	STINGagonist-26 (CF508) 是一种非核苷酸小分子STING 激动剂。STINGagonist-23 激活STING，增加STING、TBK1和IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和CCL-5的水平。STINGagonist-23 表现出抗SARS-CoV 系列的活性。
T75091	STING agonist-23
	STINGagonist-23 (CF502) 是一种非核苷酸小分子 STING 激动剂。STINGagonist-23 激活 STING，增加 STING、TBK1和 IRF3的磷酸化。STINGagonist-23 可促进肿瘤细胞中 IFN-β、IL-6、CXCL-10、TNF-α、ISG-15和 CCL-5的水平。STINGagonist-23 表现出抗 SARS-CoV 系列的活性。
T83841	STING Agonist D61 D61,Stimulator of Interferon Genes Agonist D61
	STING激动剂D61（D61）是干扰素基因刺激剂(STING)的激动剂。它在基于细胞的分析中诱导IFN3诱导的分泌性碱性磷酸酶(SEAP)报告基因和IFN-β诱导的报告基因的表达（EC50分别为52.9和116 nM）。D61（4, 6, 和8 µM）增加了编码IFN-β和化学因子（C-X-C基序）配体10（CXCL10）的mRNA的表达以及TANK结合激酶1（TBK1）、IRF3和STING在THP-1单核细胞中的磷酸化。在体内，D61（每隔一天0.25 mg/kg）在CT26小鼠结肠癌模型中减少肿瘤体积，而不影响体重。
T38161	STING Agonist C11 STING Agonist C11
	STING agonist C11 is an agonist of the stimulator of interferon genes (STING) pathway.1 It induces secretion of type I IFN from THF and MM6 cells when used at a concentration of 50 μM. STING agonist C11 induces phosphorylation of IFN regulatory factor 3 (IRF3) and increases expression of IFIT1 and viperin, but not IL-1β, IL-6, or IL-8 in THF cells in a STING-dependent manner. It reduces viral titers of chikungunya, Venezuelan equine encephalitis, o'nyong-nyong, Mayaro, and Ross River viruses gro...
T38091	3'3'-cGAMP (sodium salt)
	3'3'-cGAMP is a second messenger produced in bacteria by specific dinucleotide cyclases. It contains canonical 3'5'-phosphodiester bonds and regulates chemotaxis, colonization, and other cellular functions. 3'3'-cGAMP shows weaker binding to the adapter protein stimulator of interferon genes (STING; Kd = 1.04 μM) than 2'2'-cGAMP and 2'3'-cGAMP but has similar binding affinity to 3'2'-cGAMP (Kd = 1.61 μM) and cyclic di-GMP . 3'3'-cGAMP induces IFN-β mRNA expression in L929 cells (EC50 = 40.5 nM).
T36779	NG 25 (hydrochloride hydrate)
	NG 25 is a type II kinase inhibitor that inhibits MAP4K2 and TAK1 (IC50s = 21.7 and 149 nM, respectively).1It also inhibits the Src family kinases Src and LYN (IC50s = 113 and 12.9 nM, respectively) and Abl family kinases (IC50s = 75.2 nM), as well as CSK, FER, and p38α (IC50s = 56.4, 82.3, and 102 nM, respectively). NG 25 (100 nM) prevents TNF-α-induced IKKα/β phosphorylation and IκB-α degradation in L929 cells. It inhibits secretion of IFN-α and IFN-β induced by CpG type B and CL097, respectiv...
T38160	STING Agonist 1a
	STING agonist 1a is an agonist of stimulator of interferon genes (STING).1It induces expression of an IRF-inducible SEAP reporter gene in a cell-based assay (EC50= 16.77 μM). STING agonist 1a (12.5-100 μM) induces expression of IFN-β, IL-6, and chemokine (C-X-C motif) ligand 10 (CXCL10) in THP-1 cells, an effect that can be reversed by STING knockout or the STING inhibitor H-151 . 1.Hou, H., Yang, R., Liu, X., et al.Discovery of triazoloquinoxaline as novel STING agonists via structure-based vir...
T35654	2'2'-cGAMP (sodium salt)
	2'2'-cGAMP is a synthetic dinucleotide (CDN) that contains non-canonical 2'5'-phosphodiester bonds. It binds to the adapter protein stimulator of interferon genes , which is a component of the innate immune response that activates the type I interferon pathway when bound to cyclic dinucleotides. 2'2-cGAMP shows weaker binding to STING than 2'3'-cGAMP but binds more strongly than 3'3'-cGAMP , cyclic di-GMP , or 3'2'-cGAMP, which bind in the micromolar range (Kds = 1.04, 1.21, or 1.61 μM, respecti...
T36461	CAY10748 CAY10748
	CAY10748 is an agonist of stimulator of interferon genes (STING; IC50= 0.3794 μM in a competition binding assay).1It activates STING in STING-expressing, but not STING knockout, THP-1 cells (EC50s = 0.287 and >100 μM, respectively, in a reporter assay). It induces phosphorylation of STING at the serine in position 366, as well as phosphorylation of TBK1 and IFN regulatory factor 3 (IRF3), indicating activation of the STING-TBK1-IRF3 signaling pathway. CAY10748 increases the secretion of IFN-β an...
T10065	2',3'-cGAMP 2'-3'-cyclic GMP-AMP	STING; cGAS	Immunology/Inflammation
	2',3'-cGAMP (2'-3'-cyclic GMP-AMP) 是细胞天然免疫中第二信使，在DNA结合条件下由 cGAMP 合成酶 (cGAS) 催化形成。2',3'-cGAMP 可与 STING 结合形成二聚体，诱导干扰素-β（IFN-β）及其他细胞因子的产生和表达。
T83775	STING Agonist 12L Stimulator of Interferon Genes Agonist 12L
	STING激动剂12L是一种刺激干扰素基因(STING)的激动剂。它与野生型STING结合(IC50 = 1.15 µM)，以及STING的R232、AQ和Q变体(IC50分别为1.06、0.61和1.12 µM)，并在THP-1和RAW 264.7细胞中诱导报告基因表达(EC50分别为0.38和12.94 µM)。STING激动剂12L (5 µM)在THP-1细胞中诱导IFNB1、CXCL10和IL6 mRNA的表达。在体内，STING激动剂12L (10 mg/kg)提高了血浆IFN-β水平，并且在B16/F10小鼠黑色素瘤模型中减少了肿瘤体积和肺转移灶的数量。
T36996	MSA-2 dimer
	MSA-2 dimer is a selective, orally active non-nucleotide STING agonist (Kd=145 μM) with long-term antitumor and immunogenic activity. MSA-2 dimer is bound to STING as a non-covalent dimer exhibiting higher permeability than cyclic dinucleotide[1]. MSA-2 dimer (60 mg/kg; p.o.; 50 days) inhibits tumor growth and prolongs overall survival[1]. MSA-2 dimer (40 mg/kg; s.c.; 25 days) induces complete tumor regression[1].MSA-2 dimer (60 mg/kg; p.o.; 4 hours) increases proinflammatory cytokine (IFN-β) le...

化合物

IFN alpha-IFNAR-IN-1 hydrochloride

Cat.No: T11630

Target: Others, IFNAR

Cat.No: T12933

Target: TLR, COX

IFN-γ Antagonist 1

Cat.No: T76637

IFN-γ Antagonist 1 acetate

Cat.No: T76638

Cat.No: T73486

Target: Others

Cat.No: T22142

Synonym: RO4948191,CDM-3008

Target: HCV Protease, HBV, JAK, IFNAR, STAT

Cat.No: T0097

Synonym: MRT67307 HCl

Target: IκB/IKK, Autophagy

Cat.No: T5521

Synonym: U-54461,溴匹立明

Target: TLR

Cat.No: T38162

Cat.No: T76930

Cat.No: T64280

Cat.No: T26895

Synonym: BRD-0476,ML 187,ML187,ML-187,BRD 0476

Cat.No: T38158

Cat.No: T71839

Cat.No: T38329

Cat.No: T38328

Influenza A virus-IN-1

Cat.No: T39778

NG25 trihydrochloride

Cat.No: T69898

STING agonist-24

Cat.No: T75092

STING agonist-25

Cat.No: T75093

STING agonist-28

Cat.No: T75096

STING agonist-26

Cat.No: T75094

STING agonist-23

Cat.No: T75091

STING Agonist D61

Cat.No: T83841

Synonym: D61,Stimulator of Interferon Genes Agonist D61

STING Agonist C11

Cat.No: T38161

Synonym: STING Agonist C11

3'3'-cGAMP (sodium salt)

Cat.No: T38091

NG 25 (hydrochloride hydrate)

Cat.No: T36779

STING Agonist 1a

Cat.No: T38160

2'2'-cGAMP (sodium salt)

Cat.No: T35654

Cat.No: T36461

Synonym: CAY10748

Cat.No: T10065

Synonym: 2'-3'-cyclic GMP-AMP

Target: STING, cGAS

STING Agonist 12L

Cat.No: T83775

Synonym: Stimulator of Interferon Genes Agonist 12L

Cat.No: T36996

Cat. No.	Product Name	Target	Signaling Pathways
T10065L	2',3'-cGAMP sodium 2'-3'-cyclic GMP-AMP sodium	STING; cGAS	Immunology/Inflammation
	2',3'-cGAMP sodium (2'-3'-cyclic GMP-AMP sodium) 是细胞天然免疫中第二信使，在DNA结合条件下由 cGAMP 合成酶 (cGAS) 催化形成。2',3'-cGAMP sodium 可与 STING 结合形成二聚体，诱导干扰素-β（IFN-β）及其他细胞因子的产生和表达。
T14854	Caerulomycin A 浅蓝霉素,Cerulomycin,Caerulomycin	Antifungal	Microbiology/Virology
	Caerulomycin A (Caerulomycin) 是抗真菌和抗细菌化合物，能够诱导 T 细胞的产生。它能够抑制 IFN-γ 诱导的 STAT1 通路，从而增强 TGF-β-Smad3 信号通路。它可用于自身免疫病的研究。
TN6366	Lupinalbin A 鲁冰花
	Lupinalbin A as the most potent estrogen receptor α- and aryl hydrocarbon receptor agonist in Eriosema laurentii de Wild. (Leguminosae). It exerts anti-inflammatory effects via the inhibition of pro-inflammatory cytokines and blocking of IFN-β/STAT1 pathw

天然产物

2',3'-cGAMP sodium

Cat.No: T10065L

Synonym: 2'-3'-cyclic GMP-AMP sodium

Target: STING, cGAS

Cat.No: T14854

Synonym: 浅蓝霉素,Cerulomycin,Caerulomycin

Target: Antifungal

Cat.No: TN6366

Synonym: 鲁冰花

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04799	IFNAR2 Protein, Human, Recombinant (His), Biotinylated IFN-R,interferon (α, β and Ω) receptor 2,<...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-03145	IFN-beta Protein, Human, Recombinant IFN-β,interferon, β1, fibroblast,...	Human	CHO Cells
	IFN-beta Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 20 kDa and the accession number is P01574.
TMPY-00831	IFN-beta Protein, Human, Recombinant (hFc) IFNB,IFN-β,Interferon beta,interf...	Human	HEK293 Cells
	IFN-beta Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is A0A7R8GV38.
TMPY-03467	IFN-beta Protein, Mouse, Recombinant Ifb,IFN-β,interferon, beta 1, fibroblast,干...	Mouse	HEK293 Cells
	IFN-beta Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 20.3 kDa and the accession number is P01575.
TMPY-02647	IFNAR1 Protein, Human, Recombinant (His) interferon (alpha, beta and omega) receptor 1,IFN-α...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 48.6 kDa and the accession number is P17181-1.
TMPK-00889	IFNAR2 Protein, Human, Recombinant (aa 27-243, His) IFN-alpha/beta R2,IFNAR2,IFNbR2,<...	Human	HEK293 Cells
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Human, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-His t...
TMPK-00637	IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) β receptor10,IFNbR2,IFN α/β	Cynomolgus	HEK293 Cells
	Although interferon (IFN)-α is known to exert immunomodulatory and antiproliferative effects on dendritic cells (DCs) through induction of protein-coding IFN-stimulated genes (ISGs), little is known about IFN-α-regulated miRNAs in DCs. Since several miRNAs are involved in regulating DC functions, it is important to investigate whether IFN-α's effects on DCs are mediated through miRNAs as well. IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His) is expressed in HEK293 mammalian cells with C-...
TMPK-00342	IFNAR1 Protein, Mouse, Recombinant (His & Avi) IFN-α-REC,IFN-R-1,IFNAR1,IFN<...	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 46.9 kDa and the accession number is P33896.
TMPK-00326	IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated IFN-alpha/β R1,IFN-α/β R...	Human	HEK293 Cells
	IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPK-00325	IFNAR1 Protein, Human, Recombinant (His & Avi) AVP,IFN-alpha-REC,IFN-α/β R1,...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.2 kDa and the accession number is P17181-1.
TMPK-00343	IFNAR1 Protein, Mouse, Recombinant (hFc) AVP,IFNBR,IFN-alpha/β R1,IFN<...	Mouse	HEK293 Cells
	IFNAR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weight is 72.5 kDa and the accession number is P33896.
TMPY-01642	IFNAR2 Protein, Human, Recombinant (His) IFNARB,IFNABR,interferon (α, β an...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.2 kDa and the accession number is P48551-1.
TMPY-01640	IFNAR2 Protein, Human, Recombinant (hFc) interferon (α, β and ω) receptor 2,IFNABR,...	Human	HEK293 Cells
	IFNAR2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 51.8 kDa and the accession number is P48551-1.
TMPK-00101	IL-6 Protein, Cynomolgus, Recombinant (His) CDF,BSF-2,白介素,IL6,HGF,白细胞介素,Interleukin-6,HSF,MGI-2A,IFN...	Cynomolgus	HEK293 Cells
	IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 receptor and glycoprotein.
TMPY-02456	IFN-beta Protein, Mouse, Recombinant (hFc) Ifb,interferon, β1, fibroblast,IFN-β	Mouse	HEK293 Cells
	IFN-beta Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.7 kDa and the accession number is P01575.
TMPJ-00331	IFNAR1 Protein, Rhesus macaque, Recombinant (His) IFN-al,CRF2-1,IFN-alpha/beta receptor 1,hu...	Rhesus	HEK293 Cells
	Interferon‑alpha/beta receptor 1 (IFN‑ alpha / beta R1), also known as IFNAR1, are present in all tissues and even on the surface of most IFN-resistant cells. Isoform 1, isoform 2 and isoform 3 are expressed in the IFN-alpha sensitive myeloma cell line U266B1. Isoform 2 and isoform 3 are expressed in the IFN-alpha resistant myeloma cell line U266R. Isoform 1 is not expressed in IFN-alpha resistant myeloma cell line U266R. It interacts with STAT1 and STAT2, the interaction requires its phosphory...
TMPY-02634	IFNAR1 Protein, Human, Recombinant (hFc) interferon (α, β and Ω) receptor 1,IFNBR,A...	Human	HEK293 Cells
	IFNAR1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 74 kDa and the accession number is P17181-1.
TMPY-03828	IFN-beta Protein, Rhesus, Recombinant (mFc) interferon, beta 1, fibroblast,干扰素,interferon, β1, ...	Rhesus	HEK293 Cells
	IFN-beta Protein, Rhesus, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.4 kDa and the accession number is G7NFX1.
TMPJ-01371	Limitin Protein, Mouse, Recombinant (His) Ifnz,Lmtn,IFN-z,IFN-ζ,BGIF,interf...	Mouse	HEK293 Cells
	Limitin, also called IFN-ζ, is a secreted interferon (IFN)-like glycoprotein. Limitin has approximately 30% sequence homology with IFN-α, IFN-β, and IFN-ω and binds to the IFN-α/β receptors. Like IFN-α and IFN-β, limitin has antiproliferative, immunomodulatory, and antiviral properties, it is unique in lacking influence on myeloid and erythroid progenitors. Similar dose requirement between limitin and IFN-α was observed for the enhancement of cytotoxic T lymphocyte activity, the augmentation of ...
TMPJ-00780	IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His) Interferon α-K,Interferon α-6,IFN α6,Interferon α-5...	Human	HEK293 Cells
	Interferon α-6 (IFN-α6) is a secreted protein which belongs to the α/β interferon family. IFN-α6 is produced by macrophages, expressed at low level, only 1.0% of the average gene in this release. IFN-α6 contains interferon alpha, beta and delta domain. IFN-α has antiviral activities. Interferon stimulates the production of two enzymes: a protein kinase and an oligoadenylate synthetase.

重组蛋白

IFNAR2 Protein, Human, Recombinant (His), Biotinylated

Cat.No: TMPY-04799

Species: Human

Expression System: HEK293 Cells

IFN-beta Protein, Human, Recombinant

Cat.No: TMPY-03145

Species: Human

Expression System: CHO Cells

IFN-beta Protein, Human, Recombinant (hFc)

Cat.No: TMPY-00831

Species: Human

Expression System: HEK293 Cells

IFN-beta Protein, Mouse, Recombinant

Cat.No: TMPY-03467

Species: Mouse

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (His)

Cat.No: TMPY-02647

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (aa 27-243, His)

Cat.No: TMPK-00889

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Cynomolgus, Recombinant (aa 27-243, His)

Cat.No: TMPK-00637

Species: Cynomolgus

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (His & Avi)

Cat.No: TMPK-00342

Species: Mouse

Expression System: HEK293 Cells

IFNAR1, Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00326

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00325

Species: Human

Expression System: HEK293 Cells

IFNAR1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-00343

Species: Mouse

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (His)

Cat.No: TMPY-01642

Species: Human

Expression System: HEK293 Cells

IFNAR2 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-01640

Species: Human

Expression System: HEK293 Cells

IL-6 Protein, Cynomolgus, Recombinant (His)

Cat.No: TMPK-00101

Species: Cynomolgus

Expression System: HEK293 Cells

IFN-beta Protein, Mouse, Recombinant (hFc)

Cat.No: TMPY-02456

Species: Mouse

Expression System: HEK293 Cells

IFNAR1 Protein, Rhesus macaque, Recombinant (His)

Cat.No: TMPJ-00331

Species: Rhesus

Expression System: HEK293 Cells

IFNAR1 Protein, Human, Recombinant (hFc)

Cat.No: TMPY-02634

Species: Human

Expression System: HEK293 Cells

IFN-beta Protein, Rhesus, Recombinant (mFc)

Cat.No: TMPY-03828

Species: Rhesus

Expression System: HEK293 Cells

Limitin Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01371

Species: Mouse

Expression System: HEK293 Cells

IFN-alpha 6/IFNA6 Protein, Human, Recombinant (His)

Cat.No: TMPJ-00780

Species: Human

Expression System: HEK293 Cells

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